Penicillin Mechanism of Action animation video

Penicillin pass through porins of gram negative bacterial cell wall. The penicillin then binds to penicillin binding protein linked the cell membrane to be activated. Active penicillin binds to and inactivate transpeptidase enzyme. As a result peptidoglycans NAM and NAG sugars are not cross-linked and the cell wall collapse

[@PharmacologyAnimation]

Dear friends, a new comprehensive animation video titled "Antibacterials" was uploaded at this channel. I would be pleased if you have a look at it and send me your feedback

[@christinbendorf92]

Tetrapeptide side chains are attached to NAM not NAG

[@masoomesadraei6695]

I was struggling to understand it with the teacher's paper.. But you simply explained everything in 3 minutes
Thank you

[@aliramadan3870]

Tetrapeptide is attached to NAM
These Tetrapeptides are linked together by pentaglycine cross-link with the aid of transpeptiase ( penicillin binding protein ) and Penicillin inhibits this enzyme .

[@FIFANATICS]

Yes, this is correct though in one book I'm reading, it says pentapeptide instead of tetrapeptide

[@Kyle-vp2dk]

Correction - PBP's are transpeptidases that link different segments of the peptidoglycans together.

[@mariamgad284]

But the chains of amino acids are between NAMs not NAGs..

[@viral_memes4u]

Yes obviously

[@viral_memes4u]

Absolutely right

[@Tina-bo1sf]

Make your own natural medicine. We know the mechanism of action. Find the plant that does the same and they can kiss our ars.

[@omarafaneh13]

دكتور جهاد ارجو الترجمة للغتك العربية هناك ما لا يقل عن اربع مئة الف عربي قد يستفيد كثير منهم من هذا الجهد المبارك.

[@PharmacologyAnimation]

ان شاء الله المرحلة القادمة تكون الترجمة الى اللعة العربية يا عمر

[@omarafaneh13]

فتح الله لك من خيره وبركاته.

[@marksteve8373]

@@omarafaneh13 You ought to know English in order to truly comprehend these concepts~

[@Daydreamer-qg7zv]

You simply explained it in just 3 minutes hats off to you❤

[@washimchowdhury2524]

Quite a good animation. Quick and on point! Thank you

[@user-fl9it7ie2c]

thx a lot for your compact lecture. My knowledge belongs to you

[@basrapharmd3320]

Keep it up... V precise and simple explanation.. ♥️

[@free_at_last8141]

Great overview of the subject, thanks for posting this.

[@MD-qy4fo]

Very simple and very well explained.Thanks.

[@nourai5653]

👍🏻👍🏻 Great

[@Cheeruppy6166]

Thank you very much helpful

[@kashifofficial5820]

Absolutely stunning Allah bless you

[@HassanAliNursing]

Amazing thank you

[@gjzztrrettmmggrrertzhgyena4950]

Great efforts..💖💖💖💖💖
Thanks Sir💦💦💦💦

[@ForeignerD]

Clarifies very well, thank you

[@abal-ashrafaffan3503]

Very short and precise.. thanks much

[@thousifbanu7485]

Gud explanation

[@user-if8my6hm6r]

isnt pentapeptide and cross linking located betw NAM?

[@Ausnapify]

I dont know

[@mmproduccionmusical1350]

could you write the source/journal article where you found this information?

[@arry9396]

Thank you so much❤

[@FarahAlshabot]

Thanks!

[@pnrking]

Really high-quality content and lessons
Appreciate that 🙏🏻❤

[@misse2359]

hocam gercekten cok aciklayiciydi. Ellerinize saglik

[@shadeeduliqaab]

Jazak Allahu khayran😍🥀

[@dawarhub4682]

Very informative ❤

[@ghaziturki9756]

Excellent work 💞💞💞💞💞

[@Suresh760-p7h]

5 amino acids chain come from nam( N acetyl muramic acid). Not from nag( N acetyl glucosamine.

[@888167]

why do the bacteria even have this PBP? Is there any positive function for the bacteria?

[@PharmacologyAnimation]

I hope you will find your answer in the more detailed antibacterial video in my channel.
ruclips.net/video/Qah8-3QV9uE/видео.html

[@JustPharmacology]

These protein are not meant for pencillins but it is property of pencillins to bind them and that's why bacteria alter them and acquire resistance

[@Travelin_Man1]

One inaccuracy in the video is the representation of PBPs. Penicillin-binding proteins *are* the transpeptidases. They aren't separate molecules.

[@christinbendorf92]

Tetrapeptide side chains are attached to NAM not NAG

[@marksteve8373]

Great explanation! Thanks you :)

[@user-yk8tf9ye1u]

Why 1,3thiazol ring in cephalosporins do anti-MRSA activity

[@lunaanika5962]

Wonderful 👏👏👏

[@thabisonyawo500]

very useful video thanks

[@PickonesBrainHub]

There is only linkage between Nam to Nam

[@Official21708]

Thanks you sir 😊

[@hassinayazid99]

the cross-linkage is between NAM not NAG!

[@NQX10]

Amazing, thank you!

[@daouduni6006]

Thank you so much 🙏🏻

[@farahnaz1581]

nice explaination

[@btslove_forever]

Nice video tq sir

[@sumitsaini153]

Quite good 👍

[@MatTroiLuoi]

But penicillin doesnt work with Gram negative bacteria

[@PharmacologyAnimation]

Penicillins as a family have gram negative spectrum. I have just uploaded a new video titled Antibacterials, I would be pleased if you have a look at it.

[@BadBoy-uj3gg]

Thank you 🙏

[@shortsfootball360]

Great!!!

[@perdantpersonne1279]

Thank you sm for this video🤍

[@katetosh]

Why does penicillin not work on candida albicans? Is it due to it being made up of Chitin, not peptidoglycan? or is there more to it?

[@JustPharmacology]

Candida is fungus and cell wall is different, some what more complex ergosterol, glucan and chitin are targets

[@obioraokafor831]

Perfection

[@arjunraj7577]

very much helpful

[@ArmedBubble15]

Thankyou!

[@DrNBShridhar]

Please give permission to use them for education purpose..

[@PharmacologyAnimation]

You welcome to use them for education purpose at any time

[@DrNBShridhar]

Thanks

[@user-cb5su9yt5i]

What is the role of NAM and NAG?

[@anita26069]

thank you!!!

[@kundankumar-dj1qs]

Nice

[@sheryariqbal9697]

Please add subtitles

[@kyletang7]

The peptide cross-links should be between the peptides coming off of the NAMs, not NAGs. ruclips.net/video/a81nHSqQuvI/видео.html

[@smsma6655]

جميل

[@ghatrmmobile4137]

finE siR 💛💚💙❤🌺🥀🌹

[@user-ti3yf3op4c]

دكتور اعمل لنا بالعربي او حط الترجمة للعربية جزاك الله خيرا

[@PharmacologyAnimation]

ان شاء الله المرحلة القادمة تكون محاولة التعليق الصوتي باللغة الهربية على الفيديوهات

[@user-ti3yf3op4c]

@@PharmacologyAnimation ان شاء الله

[@roselinrathinasamy1411]

👍🏻👍🏻👍🏻

[@projectszymon5591]

why 40 old men prof, sounds like 13 years old girl

[@PharmacologyAnimation]

the narrator is a third year medical student girl

[@FIFANATICS]

Transpeptidase itself is one of PBPs
This guy is tripping

[@oliverharris6116]

A Level Biology 4TW

[@pathnis]

I almost got killed by doctors because of this stupid drug

[@tedmcmanus7166]

based

[@vamshikrishna7491]

Wrong mechanism of action

[@PharmacologyAnimation]

Why do you think it is wrong mechanism of action?

[@anshulsharma7627]

Yuk quality audio

[@NearCentury]

conner hagerman out.

[@sadiahaque8389]

Wrong