This is literally the best visual representation and explanation I've found about cell wall synthesis Thank you so much for this! You're literally helping me pass my board exam
In E-coli, a gram negative bacteria, the tetrapeptide side chain at the third position contains ‘Meso-diaminopimelic acid’ and not L-lysine. And the covalent linkage is formed between D-alanine & meso-diaminopimelic acid.
Thanks a lot! The best video and the best explanation about this theme. Besides I'm italian and your English is so simple and understandable that I hadn't any difficult.
Hey, I would like some help, what about the change of hydrophilic->hydrophobic when binding to bactoprenol? also, missing the part of 5 glycin brought by tRNA binding to the L-Lys amino acid? could you clarify this part, please? @edukesh
Great video. A mild correction needed. In Gram negative bacteria, the third amino acid which is involved in cross linking with the 4 th amoino acid i.e D- Alinine, is Diaminopimellic acid and not L- Lysine. Thnaks.
But plz tell me How does this happen in 3D ? I mean the Nam is attached to another Nam ....adjacent .lower and above .....so does it make thress links in the same way ?
Hello! Great video! I think there's a misrepresentation error in the diagrams modeling the gram+ and gram- cell walls at 1:20. In these representations, the cross-links are shown between the two types of sugars, NAG and NAM, while they actually form between two NAM sugars. This could be confusing for young students who are encountering these concepts for the first time.
My medicinal chemistry exam is tomorrow, and I had some questions regarding the MOA of the drugs you mentioned and the cell wall itself, but thanks to you I understand everything now, so THANK YOU VERY MUCH! May God bless you 🙏🏻
This is the best explanation of this process that I've seen. It might be the only video I've seen about it actually. Thanks so much!
This is literally the best visual representation and explanation I've found about cell wall synthesis Thank you so much for this! You're literally helping me pass my board exam
I can't believe this lesson is free! It's perfectly explained, thank you!
In E-coli, a gram negative bacteria, the tetrapeptide side chain at the third position contains ‘Meso-diaminopimelic acid’ and not L-lysine. And the covalent linkage is formed between D-alanine & meso-diaminopimelic acid.
You are right. The tetrapeptide side chain should be L-Ala/D-Glu/DAP (Diaminopimelic acid)/D-Ala
Source: Sherris Medical Microbiology 8th Edition
Best explanation ever in socialmedia .. ❤
You explained it perfectly. Thank you! I finally understand NAG and NAM and how the cell wall is inhibited by antibiotics.
Glad to hear that. Thank you for your feedback!
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Your explanation is amazing!This is really the best explanation for the process I have ever seen!
Great video! Thank you for putting this together. It was well explained and the diagrams were very helpful.
Absolutely amazing explanation! Thank you for make it so clear
I'm watching this video again after 5 months. This is the only deep explanation of this topic in RUclips, thanks :)
Wow. You just blew my distance learning Covid mind. Thank you.
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Thank you for great video. Your explanation is absolutely fantastic!
GREAT VIDEO for a 2nd year med student! Thank you!
😍Thank you so much for this clear cut explanation. Needed it badly!!
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Great explanation, thanks. Only 1 clarification: bactoprenol is not a protein but a lipid, in particular an hydrophobic alcohol.
The best explanation of this work ever thank you so much!
Perfectly concise! Thank you!!!
Thanks a lot! The best video and the best explanation about this theme. Besides I'm italian and your English is so simple and understandable that I hadn't any difficult.
Thank you so much! Your explanation helps me immensely with my pharmacology studies.
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perfect demonstration indeed, thanks endlessly
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Very impressive. It is so well explained. Thank you so much. It helped me a lot!
Finally explanation for G+ peptidoglycan biosynthesis, but the whole video is great. Thank you!
a perfect way in explanation. so organized
Thank you so much. This video explained everything in a simple manner ❤️
Finally found the video on this topic.. Thankyou sir 😊
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Great explanation. Thank you very much!
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This video was perfect, thank you!
perfeito é vc, seu lindo
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Very helpful. Thanks a ton!
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with us☺️
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The best explanation . Thank u sir 😍😊
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Best best explanation!
Hey, I would like some help, what about the change of hydrophilic->hydrophobic when binding to bactoprenol?
also, missing the part of 5 glycin brought by tRNA binding to the L-Lys amino acid?
could you clarify this part, please? @edukesh
Excellent excellent!!👌👌👌👌👌👌
This is reallllyyyyy gooooddd thank u so so so much
Thanks, please keep making videos!!!!
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superb sir. detailed and clear explanation...
Thanks for this great video ❤️
what app did u use to record this video
sound quality is great
Much needed beautifully explained sir✨
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You deserve +100000 likes .thaank you soo much so helpfull
Nicely explained ...easy to understand!
Great video. A mild correction needed. In Gram negative bacteria, the third amino acid which is involved in cross linking with the 4 th amoino acid i.e D- Alinine, is Diaminopimellic acid and not L- Lysine. Thnaks.
Very good Explanation sir .. Really helpful 😊😊😊
Thanks. Very well done.
Best explanation ever seen
Great video!
Thank u so much 🥰💕..god bless
Thanks a lot u explained it really well i understood all the stuff😌
Great explaination sir!
🙏🙏
But plz tell me
How does this happen in 3D ?
I mean the Nam is attached to another Nam ....adjacent .lower and above .....so does it make thress links in the same way ?
Thank you!
Worth to watch 🤗🤗
it was so beneficial, thank you
Excellent explanation
Excellent job. Please make more videos.
Best explanation
I wanna understand the last slide if u mean that crosslinking in E.coli is differ than that in Staph??
Thanks so much!!
Great illustration
Great content
thank you very much
Nice one ....must watch . .
Thank you sir 🥰🥰 very much useful 🙏
Just a clarification. Bactoprenol is not a lipoprotein but a lipid.
hello which book is used as reference for this??
You help me I swear to god ❤️ thank bro
Awesome!
why there are only few lectures on your channel . how to access more lectures ?
how does the terminal d alanine helps in covalent bonding before being detached ??????????
Good explanation 👍
thank you!!!!!
Hello!
Great video!
I think there's a misrepresentation error in the diagrams modeling the gram+ and gram- cell walls at 1:20. In these representations, the cross-links are shown between the two types of sugars, NAG and NAM, while they actually form between two NAM sugars. This could be confusing for young students who are encountering these concepts for the first time.
Great video 👍
Nice and useful 👍😊
My medicinal chemistry exam is tomorrow, and I had some questions regarding the MOA of the drugs you mentioned and the cell wall itself, but thanks to you I understand everything now, so THANK YOU VERY MUCH! May God bless you 🙏🏻
Thank you for the kind comment. Good luck in the exam.
very well explained
well explained. bravo
Thank u so much
perfect❤
Thank you sir it was so helpgul