Antibiotics - Mechanisms of Action (Classification) and Antibiotic Resistance

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  • Опубликовано: 10 июн 2024
  • Hey Friends,
    Antibiotics are a specific type of medicine directed against bacteria. Penicillin was the first available antibiotic on the market. There are multiple antibiotics such as Beta Lactams, Tetracycline or Rifamycin. All have different mechanisms of action. The overuse of antibiotics can promote mutations in the bacterial genome. When the mutation alters the protein structure of one of the antibiotic targets (enzymes e.g. Transpeptidase) by chance this can lead to antibiotic resistance. Multiresistent germs are extremely dangerous and we have to find new antibiotics to prevent to fight them but also be more responsible with the antibiotics we have!
    Best
    Henrik
    References:
    Good videos for medicine students:
    • Antibiotics: Cell Wall...
    • Antibiotic Classes in ...
    Papers and Reviews:
    aac.asm.org/content/64/3/e012...
    www.intechopen.com/books/anti...
    pubmed.ncbi.nlm.nih.gov/29109...
    pubmed.ncbi.nlm.nih.gov/23489...
    Thanks for watching and reading!
    If this video was helpful or entertaining or whatever, give it a thumbs up.
    Make sure to subscribe for more science-related short videos.
    Ciao
    Chapters:
    0:00 What are antibiotics?
    1:57 MoA: Inhibition of Cell Wall Synthesis
    3:17 MoA: Inhibition of Protein Synthesis
    4:42 MoA: Inhibition of Nucleic Acid Synthesis
    5:24 Wonder Drugs?
    5:48 Antibiotic Resistance
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Комментарии • 71

  • @bionicallychallenged7290
    @bionicallychallenged7290 3 года назад +12

    Thank you for that! Your videos have aided me in my writing. I've used your channel to start my research in a lot of areas regarding biopsychology.
    Thank you for your time!

    • @henrikslab
      @henrikslab  3 года назад +1

      Thank YOU and you´re welcome!

  • @sachingswamy
    @sachingswamy 3 года назад +8

    That's an amazing and simplistic explanation of the action of antibiotics and mainly #antibioticreistance

  • @genevieveemefaasare8352
    @genevieveemefaasare8352 2 года назад +3

    Great master piece . thanks a lot for sharing

  • @hannashanavas8074
    @hannashanavas8074 2 года назад +3

    Thank you so much. Explained very well👏👏

  • @mariasanchezmenjivar8432
    @mariasanchezmenjivar8432 2 года назад +1

    ¡Gracias! Excellent video, a hug from Honduras...

  • @earth2k66
    @earth2k66 2 месяца назад +5

    Bacteria: What doesn't kill me, makes me stronger.
    Bacteriophage: Nah, I'd win. 🗿

  • @suedolma7768
    @suedolma7768 4 месяца назад +1

    SO CLEAR. thank you

  • @simonidimitriadou7224
    @simonidimitriadou7224 3 года назад +11

    This is so helpful for my medical microbiology exam

  • @afsaneemami580
    @afsaneemami580 Год назад +1

    Thank you it was very useful. 🌼

  • @caaanelli4307
    @caaanelli4307 3 года назад +1

    Very helpful video!

  • @ChanTap-dp6tj
    @ChanTap-dp6tj 7 месяцев назад +1

    Thank you, you teaching good, continue

  • @Isabelangler
    @Isabelangler 3 года назад +1

    Great video my friend

  • @exildahkapasa8051
    @exildahkapasa8051 11 месяцев назад

    Thank you so much ,it really helped😊

  • @rosaamaldonado5760
    @rosaamaldonado5760 4 месяца назад +1

    Excellent video

  • @austinouda1886
    @austinouda1886 27 дней назад

    wow such a strong explanation\

  • @Asuthoshi
    @Asuthoshi 3 месяца назад +1

    Excellent 👍

  • @mominjaved7616
    @mominjaved7616 2 года назад +4

    Alhm du lillahh.. Allahh has given a very good explanation method👍👍👍👍

    • @edukee
      @edukee 2 года назад +6

      Allah has given nothing at all, I am a native Arabic speaker, was taught everything about Islam in school, forced to read the whole quran and ahadith, everything said about human body in Islam is outright wrong. stop taking credit from people's hard work with bullshit.

    • @meryemk.8344
      @meryemk.8344 Год назад +3

      @@edukee 👏🏼

  • @frenny9903
    @frenny9903 2 года назад +1

    good explaination

  • @madelineanabella6400
    @madelineanabella6400 5 месяцев назад +4

    I have never taken an antibiotic . I’ve always used superfoods etc to boost my immune system. Im sure I will need antibiotics at some point. It’s important to boost your immune system by eating as natural as possible, exercise and sleep ( not over sleep though unless you r sick. This has kept me from getting sick or if I am sick, it’s not long. I also take a multivitamin every day. My mom was a vitamin believer and always gave us a multivitamin every day. My brothers and parents were pretty healthy . I am blessed and hopefully can help other people with this info. I believe in antibiotics if they r needed. Bacteria infections r no joke.

    • @iishyxvietxboyii1
      @iishyxvietxboyii1 5 месяцев назад

      You’ve never had a bacterial infection after a cold or flu? I’m on Amoxicillin right now, lol.

  • @Doraemon-mh2lk
    @Doraemon-mh2lk 2 года назад +2

    Thank youuu! 🤍🇳🇵

  • @RizwanKhan-co5ni
    @RizwanKhan-co5ni 6 месяцев назад +1

    Very good🎉

  • @abujafar7092
    @abujafar7092 Год назад +1

    Thank you so much❤

  • @pitkamatka
    @pitkamatka 2 года назад +8

    Great video! 💯 I'm just wondering whether cell wall synthesis disrupting antibiotics work on gram negative bacteria which have another layer of protection outside their cell wall. Also do you know, how do bacteria take up antibiotics that target their protein synthesis? 🤔

    • @madelineanabella6400
      @madelineanabella6400 5 месяцев назад

      That’s what I’m wondering also. They say by 2050 if there r not advancements 10 million people will die a year from infection because bacteria 🦠 has evolved to get past antibiotics.

  • @user-kr8dp4ji9r
    @user-kr8dp4ji9r 4 месяца назад +1

    Very nice

  • @amandaallen1898
    @amandaallen1898 3 месяца назад +1

    Good overall explanation, however please may I suggest an edit. Antibiotics make bacteria unstable not instable. This is the action that kills or severely disrupts bacterial proliferation.

    • @henrikslab
      @henrikslab  3 месяца назад +2

      "unstable" might be a better term here, I agree!

  • @jujum849
    @jujum849 2 года назад +1

    thank you!

  • @satyabratasvlog
    @satyabratasvlog 3 года назад +1

    VERY NICE

  • @mohammedal-hammadi5085
    @mohammedal-hammadi5085 3 года назад +1

    Thank you

  • @mominjaved7616
    @mominjaved7616 2 года назад +1

    Kindlyy make more n more vdeos on biotech

  • @venkybly
    @venkybly 4 месяца назад +1

    Tq for the info

  • @user-sk5wq5gc3b
    @user-sk5wq5gc3b Год назад +1

    great

  • @mominjaved7616
    @mominjaved7616 2 года назад +1

    I like ur videossss soooo mchhhh

  • @hakikamwambene7815
    @hakikamwambene7815 Год назад +1

    Thank u

  • @arkaprabhabhattacharya2517
    @arkaprabhabhattacharya2517 4 месяца назад +1

    You and “synthesis”
    Benedict Cumberbatch and “penguins”
    People and “Benedict Cumberbatch”

  • @zera2314
    @zera2314 2 года назад +66

    It's interesting how you pronounce synthesize perfectly, yet you pronounce synthesis as "thinthethis".

    • @virtue1495
      @virtue1495 Год назад +3

      😂😂😂

    • @daymarelc869
      @daymarelc869 Год назад +1

      Exactly

    • @barrowfull-qs2dk
      @barrowfull-qs2dk 6 месяцев назад

      Interesting how a ww2 wonder drug might produce the fabled super germ in man

    • @olga9555
      @olga9555 4 месяца назад

      This voice is computer generated. Early version probably, not perfect

    • @zera2314
      @zera2314 4 месяца назад

      @@olga9555 what? haha no it's not

  • @phillemonjeremia8296
    @phillemonjeremia8296 2 года назад +1

    Which antibiotic is more stronger?

    • @henrikslab
      @henrikslab  2 года назад +1

      depends on so many things... e.g. the bacterial strain

    • @phillemonjeremia8296
      @phillemonjeremia8296 2 года назад

      @@henrikslab which can cure syphilis within 2 months

    • @henrikslab
      @henrikslab  2 года назад

      @@phillemonjeremia8296 www.cdc.gov/std/syphilis/treatment.htm

  • @tarlinsaini7650
    @tarlinsaini7650 6 месяцев назад +2

    SYNTHESIS

  • @dott.yaacoubandergassenaqu3623
    @dott.yaacoubandergassenaqu3623 2 года назад

    #MedicalsystemImmanentrequest #PhilosophyorPoliticsMistakes

  • @sakalarichard784
    @sakalarichard784 Год назад +1

    👊👊👊👊👊👍👍👍👍💪💪💪💪💪

  • @abuturab3989
    @abuturab3989 Год назад +1

    If antibiotic does not work against viruses why doctor prescribe it for viral fever

    • @henrikslab
      @henrikslab  Год назад

      www.healthline.com/health/viral-fever#treatment
      This is very likely wrong of the doctor. If at all, viral fever should be treated in severe cases with antivirals (e.g. Tamiflu). Antibiotics should not be prescribed in case there is no bacterial infection.

  • @minhhunglam5347
    @minhhunglam5347 3 месяца назад +1

    Hi

  • @abdussamad5617
    @abdussamad5617 Год назад

    Yra Der takra ye kho ungriz ye sa ba awayo

  • @minhhunglam5347
    @minhhunglam5347 3 месяца назад +1

    Help me

  • @anitachavan1507
    @anitachavan1507 11 месяцев назад +1

    It was 1929 not 1928

    • @henrikslab
      @henrikslab  11 месяцев назад

      My sources say 1928:
      www.sciencemuseum.org.uk/objects-and-stories/how-was-penicillin-developed
      www.history.com/this-day-in-history/penicillin-discovered

  • @Rom.z
    @Rom.z 2 года назад +2

    جسق

  • @MedicalBroadcast
    @MedicalBroadcast 2 месяца назад +1

    Please be careful with antibiotics use.

  • @nilo5016
    @nilo5016 6 месяцев назад

    Dieser deutsche Akzent 😂

  • @minhhunglam5347
    @minhhunglam5347 3 месяца назад +1

    Help me