Resolving Chronic Inflammation using SPMs: A Two-Phase Approach with Ashley Koff RD

Practitioners, if specialized pro-resolving lipid mediators (SPMs) aren't already on your radar, you'll be a convert by the end of this New Frontiers episode.
In functional medicine, we excel at addressing inflammation through nutrition and lifestyle. However, brilliant researchers like Dr. Charles Serhan from Harvard Medical School have shown us that resolving inflammation requires a two-phase approach. We need to shift gears, rally the cleanup crew, start the repair process, and turn down the volume on the immune system. This transition from inflammation to resolution is exactly what our guest, Ashley Koff, RD, will discuss.
We'll explore why SPMs, discovered by Dr. Serhan, are crucial for healthy inflammation resolution and how Metagenics has developed a product using the patented Serhan method that has numerous clinical applications, from managing inflammation and pain to addressing neurodegenerative conditions, autoimmunity, and even infertility. We'll also delve into factors that influence our ability to convert omega-3 and -6 fatty acids into these superstar molecules, such as diet, genetics, inflammatory bias, and poor vagal tone.
This conversation is packed with clinical pearls for your practice and personal use. Enjoy.~DrK
Check out the show notes at www.drkarafitzgerald.com/fxme... for the full list of links and resources.
Guest Details
Ashley Koff RD is a 25+ year award-winning practitioner, developing and providing truly personalized solutions for patients, practitioners and organizations. Today, she helms a team at The Better Nutrition Program a company she founded in 2019 and is a fractional Chief Nutrition Officer for entities like Vitaboom.
Ashley Koff, RD - tinyurl.com/2drp29ky
Founder of The Better Nutrition Program - thebetternutritionprogram.com/
Phone: [phone]
Email: [e-mail]
Thank you to our sponsor
Metagenics: tinyurl.com/4um983ed
SPONSOR PROMO
*Get 15% off Metagenics SPM Active product only. Use codes SPMW624US (US) or SPMW624CAN (Canada) at tinyurl.com/4jc9np3y (Offer expires 7/15/24. Max order value $500. For consumer purchases only.)
Show Notes
Metagenics Institute: www.metagenicsinstitute.com/
NFFM Podcast: Specialized Pro-Resolving Mediators (SPMs): As Close to a Panpharmacon as We Can Get? tinyurl.com/4a249zvc
Latest Updates on Specialized Pro-Resolving Mediator (SPM) Science by Charles Serhan, PhD, DSc tinyurl.com/22c92dky
12/15-lipoxygenase activity promotes efficient inflammation resolution in a murine model of Lyme arthritis tinyurl.com/pm95x6vb
Fish Oil Supplementation Modulates Immune Function in Healthy Infants tinyurl.com/3cd434t3
Arachidonic acid supplementation transiently augments the acute inflammatory response to resistance exercise in trained men tinyurl.com/2fvjvdut
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[@mutantryeff]

SPMs have resolved a major inflammation issue from arthritis in my upper back. I was using a combination of tizanidine and oxycodone, but after my first day of using SPMs the use of this combination has been reduced to maybe approximately once a week. Currently taking 1g of SPM in the morning and 1g in the evening. Additionally, I sleep through the night.