First comment I ever left on a youtube video, just wanna let you know that your lectures are really helping me a lot with biochemisty since they are well structured and easy to follow through. Plus your drawings are perfectly visible, which is definitly not the case for every ''youtube lecture''. Thanks a lot and keep up that good work!
Your lectures are literally my go to. You do the connections, you give the overview, there's no searching no pounding for answers. Thanks for your fantastic channel.
Can you recommend a RUclips vid on the differing mechanisms for absorption at the intestinal canal for each sugar to show the difference between sucrose and fructose uptake?
I thank you so much for all your efforts you do not stop saving my life every time I break down you are just up to it sir! you're making me loving biochemistry lol
i always end up looking at the comments half-way thru his videos to see if everyone else is as shook as i am by how easy he makes these hard ass concepts lmaoooo
Thank you very much for all your efforts put in making these comprehensible videos. I tried to study this topic from my Biochemistry textbook and the ppt I got from the lesson, but i just could not understand it. Thank you for explaining this process in a structured and a simple way.
Great lecture! for funsies/clinical tie in: the differences between nonclassical v. classical galactosemia. Since you also talked about fructose: essential fructosuria and hereditary fructose intolerance. (Not sure if you have a time limit on your lectures? Clinical ties in helps me remember the pathways better.)
Hi There! Question: Why is it called the Galactose-Fructose Pathway? It doesn't seem like fructose in involved. More seems like a Galactose-to-Glucose Pathway?
Amazing lecture, thank you! Just one question: At 13:32 the substrate of Phosphoglucomutase is presented as G-1-P. But didn't the previous reaction yield UDP glucose?
from what i understood, it just regenerated it (kinda in the way enzymes work, they aren’t used up in the yield reaction) so udp glucose just goes to exist in the cell, while phosphoglucomutase acts on the product of the second reaction - glucose 1-phosphate
Good afternoon, I'd very much like to understand where on the fructose metabolism is the flaw that leads to fructose malabsorption... I have fructose malabsorption, as well as lactose malabsorption, and i'm trying to learn what's happening to my body. I'd be very greatfull if you'd be kind enough to give me some instructions on the matter, for I'm having a hard time finding good material online, such as yours is.
I've heard that 80% of glucose goes to the muslces and 20% goes to the liver whereas Fructose is the exact opposite i.e. 80% to the liver and 20% to the muslces... does anybody know what the split for lactose is?
A year late but Galactose1p is converted to UDP Galactose via a UDP transferase. Then UDP galactose is epimerised to UDP glucose via epimerase. UDP glucose then dumps its UDP to another galactose and itself becomes G1P which then is converted to G6P by a mutase. So overall it's a cycle.
Reading some articles on mitochondria I keep seeing the claim that galactose produces no net ATP when fed into glycolysis. However, I can’t see what step is making its metabolism more costly (by 2 ATP!), can someone point it out?
+Ekene Okeke Mutases shift a group from one position to another within the SAME molecule while a transferase shifts a group from one molecule to a different molecule. Hope that helps
@@alicegillingham421 I hope that went well for you. I have just started a week ago, so step out if the way, miss, it's MY turn to suffer. Have you got any advice for the new recruit? Need I some antidepressants?
@@sammipanini it went really well, i recieved A+. Partly cause of the great teachers for sure. My advice is... repeat again and again and try to make a complete picture of how these processes cooperate within the body. And again, repeat! Tell me about your exam once you pass it)
@@alicegillingham421 That bioc A+ sure is one of the biggest flexes a person can have. Congrats :) I will make sure to keep your advise in mind. Will let you know when I pass it. But more importantly, I will also blame it on your advise if things go downhill for me. Cheers, Stranger. Take care.
First comment I ever left on a youtube video, just wanna let you know that your lectures are really helping me a lot with biochemisty since they are well structured and easy to follow through. Plus your drawings are perfectly visible, which is definitly not the case for every ''youtube lecture''. Thanks a lot and keep up that good work!
Your lectures are literally my go to. You do the connections, you give the overview, there's no searching no pounding for answers.
Thanks for your fantastic channel.
A testimony to good teaching. 5 years from the release of this video and still helping people like me get through the tough courses. Thank you!
You are a gentleman and a scholar
I love how the bonds are different colors so we can quickly tell what's what.
Thank you for all your hard work. These are super helpful.
Makes biochemistry really easy! Thank you!
These videos are a godsend. You are extremely good at simplifying and teaching complex subjects.
my biochem professor should be ashamed of herself after watching this
😂
thank you........your lectures make my medical school life easier.......from a suffering zimbabwean student
When I pass this BIC I’ll come back to your YT to give you a big thank youuuu, this is awesome!
You have all the lectures that I have to study for biochemistry. Thank you so much for preparing them!
slaytlardan bişey anlamayıp ben de buraya geldim
Wonderful explanations and diagrams . Thank u
you are my knight in shining armor, thank you so much for this helpful lecture
thank u, honestly and sincerely
You’ve helped me so much, so thank you for these helpful videos
Fantastic!
6 years later ...thank you✨
Outstanding as always 😊😊
Awesome man , your lectures are of great help 😊
Can you recommend a RUclips vid on the differing mechanisms for absorption at the intestinal canal for each sugar to show the difference between sucrose and fructose uptake?
I thank you so much for all your efforts you do not stop saving my life every time I break down you are just up to it sir! you're making me loving biochemistry lol
your videos are great and drawings are very clear THANK YOU
You are amazing .Thanks a lot.!!!
Thank you for this wonderful lecture. Really grateful!
Thank you! Very well explained and easy to follow.
Love your videos ! Explained precisely
you are the best ever
You're saving me in biochemistry 2-- thank you :)
+katie herbst yeah, me too. i watch his videos daily
this is fantastic
i always end up looking at the comments half-way thru his videos to see if everyone else is as shook as i am by how easy he makes these hard ass concepts lmaoooo
thank uu so much this was so useful !
Thank you very much for all your efforts put in making these comprehensible videos. I tried to study this topic from my Biochemistry textbook and the ppt I got from the lesson, but i just could not understand it. Thank you for explaining this process in a structured and a simple way.
Thanks a lot. You are a face saver !!!
Great lecture! for funsies/clinical tie in: the differences between nonclassical v. classical galactosemia. Since you also talked about fructose: essential fructosuria and hereditary fructose intolerance. (Not sure if you have a time limit on your lectures? Clinical ties in helps me remember the pathways better.)
quocodile yup they are quite important as well because as doctors you would need to know about it more as no patient will ask you the pathways
Thank you SO much!!
Thank you this helped me a lot
thank you so much
you are awesome!
Great video thanks!!
Very nice and simple explanation, thanks dude :)
Well Done. thank you.
Thanks..you are the best
ur just awesome..... 😀😀😀😀....
Thanks
Awesome 🤩
simple and helpful ☺ thank u sir
I wish if i could make another version of you and replace it with my current instructor :((( , you are really helpful and worth more subscriptions
oh my GOD. you SAVEDDDD me
thank you so much. it is very useful for my exercise . :)
Life saver
L E G E N D!! Thanks for your videos king!
U MAKE biochemistry understable tnk u sir
Hi There! Question: Why is it called the Galactose-Fructose Pathway? It doesn't seem like fructose in involved. More seems like a Galactose-to-Glucose Pathway?
It is because the glucose formed is also converted to fructose to continue with glycolysis
Might be glucose one phosphate will convert into fructose one phosphate and will follow the same pathway with he discuss earlier.
@AK LECTURES I think you meant galactose-glucose interconversion pathway
Coloured this man green,= he is from planet MARS.😍
Thanks !!!
MY LECTURES SAY SOMETHING ABOUT URONIC ACID PATHWAY AND I DON'T KNOW WHAT IT IS...CAN U MAKE A VIDEO??
Can you please do a lecture on uronic acid pathway too?
7:25 for Galactose metabolism guys.
In step 2, why is the double-bonded oxygen on c1 rather than on c5?
the best
you are the best :-)
Why do we have a proton produced upon phosphorylation of fructose with it not being produced upon phosphorylation of glucose?
love it ~~~
Thankyouu ;)
Amazing lecture, thank you!
Just one question: At 13:32 the substrate of Phosphoglucomutase is presented as G-1-P. But didn't the previous reaction yield UDP glucose?
from what i understood, it just regenerated it (kinda in the way enzymes work, they aren’t used up in the yield reaction)
so udp glucose just goes to exist in the cell, while phosphoglucomutase acts on the product of the second reaction - glucose 1-phosphate
Why you don't speak about the vitamins
I would like to understand the vitamins from u.
Thanks for all what you have done
Good afternoon,
I'd very much like to understand where on the fructose metabolism is the flaw that leads to fructose malabsorption... I have fructose malabsorption, as well as lactose malabsorption, and i'm trying to learn what's happening to my body. I'd be very greatfull if you'd be kind enough to give me some instructions on the matter, for I'm having a hard time finding good material online, such as yours is.
you look and sound like Leonardo di caprio! Wow! :) keep going
I've heard that 80% of glucose goes to the muslces and 20% goes to the liver whereas Fructose is the exact opposite i.e. 80% to the liver and 20% to the muslces... does anybody know what the split for lactose is?
How does the fructose become a straight chain molecule, without any enzymatic reaction?
Where does the first UDP glucose come from before any of the “UDP galactose converting into UDP glucose” reactions?
A year late but Galactose1p is converted to UDP Galactose via a UDP transferase. Then UDP galactose is epimerised to UDP glucose via epimerase. UDP glucose then dumps its UDP to another galactose and itself becomes G1P which then is converted to G6P by a mutase. So overall it's a cycle.
Reading some articles on mitochondria I keep seeing the claim that galactose produces no net ATP when fed into glycolysis. However, I can’t see what step is making its metabolism more costly (by 2 ATP!), can someone point it out?
Why is it called the galactose-fructose interconversion pathway ?
For the screenshot! 10:59
difference between a transferase and a mutase?
+Ekene Okeke Mutases shift a group from one position to another within the SAME molecule while a transferase shifts a group from one molecule to a different molecule. Hope that helps
+AK LECTURES (Andrey K) thx
Hello, thank you for your lectures. I've got a question:
What happens to the UDP-galactose?
They got converted to UDP-glucose in step 3. I think is serves to regenerate reactants for step 2. 9 months too late lmao
@@sammipanini i took my biochemistry exam this summer, thank you)
@@alicegillingham421 I hope that went well for you. I have just started a week ago, so step out if the way, miss, it's MY turn to suffer. Have you got any advice for the new recruit? Need I some antidepressants?
@@sammipanini it went really well, i recieved A+. Partly cause of the great teachers for sure. My advice is... repeat again and again and try to make a complete picture of how these processes cooperate within the body. And again, repeat!
Tell me about your exam once you pass it)
@@alicegillingham421 That bioc A+ sure is one of the biggest flexes a person can have. Congrats :) I will make sure to keep your advise in mind. Will let you know when I pass it. But more importantly, I will also blame it on your advise if things go downhill for me. Cheers, Stranger. Take care.
Wow
25-3
some times the video become inclear while chromocast idont know why have you any idea
please turkish subtitles
Took a breath at 8:23
you caught me! ;-)
gdts
ru9
Why do I feel that I'm gonna fail whenever I watch all lectures D:
Ur lectures are great but I feel so dumb after watching :((
I really hope you passed
I lowkey got put off when i saw the writing in the back...
What?
lots of data on screen,,,,,,,,,,,,,
4:49 he put dixydroxy instead of dihydroxy do better man 🤫
thank you very much ...