Big thank you to Prof Murphy and the team. I used the neurology playlist as a foundation for my part 1 residency exams in neurology. In addition to it I reviewed other topics covered on the channel. It was the best decision. I passed the exam and hopefully will start residency soon. My appreciation and respect to the team.
Masha Allah I'm from Somalia🇸🇴 We proud of You Me and My friends For your Hardworking Thank you For Your Helping us With Out you I'm sure that i can't know something About Medicine. Thank you.
The first question (at 18:36) is actually really smart. Kidney disorders can either increase (e.g. glomerulonephritis, diabetic nephropathy) or decrease glomerular capillary permeability. But, if the condition was associated with increased clearance (increased glomerular capillary permeability), there would probably be no need for dialysis => there likely is decreased clearance.
We just started pharmacology course in school, this is the first video I'm watching on it and I am so happy because it has killed every single fear I had about pharm. Thank you ninja nerd
Can you please do the rest of the pharmacology lessons this days please 🥺 .. I have exams after 2 weeks and your videos help a lot and facilitate the whole situation professor ! .. may Allah bless you and your beloved ones 🤍
You are delivering the most helpful and very educational material. Thank you on behalf of all! Let's support this channel by subscribing, liking, commenting! So worth!
Never understand pharmacokinetics during my years at uni..u just clear my confusion on this...I will enroll if offer online pharmacology courses..keep up with good work 👏
Zack kindly Make a video on Etiopathogenesis and immunehistochemistry on lukemias and lymphomas .. These 2 topic Are so confusing While we Are diagonstic a patient
Regarding the first question, wouldn't undergoing dialysis compensate for the pharmacokinetic alterations of the drug caused by the renal impairment, eventually leading to no change in half-life and necessary dosage?
60 hours (t 1/2 = 5) would best approximate the half life of the Drug Ninja since over 96% of the drug is cleared. At 48 hours, roughly 94% of the drug is removed. How is 48 hours considered a steady state when that is less than 95%? Enjoyed the video, nonetheless!
I love all your videos! My educator in icu refers us to your videos, I use them for university, clear and detailed enough. Thank you so much! 🙏🙏🙏🙏 lifesaver hahah Curious, are you NP or phd?
Zero-order kinetics is non-linear because the rate of elimination does not change proportionally with the drug concentration. As a result, small increases in dose can lead to disproportionate increases in drug concentration in the body. • Example: Phenytoin and ethanol at high concentrations.
Thanks for the video, however, something needs to be cleared up here. if they say a drug follows nonlinear kinetics it means Zero order kinetics. some one may be confused by the explanation
If she’s suffering from renal disease, doesn’t that mean that more of the drug will be eliminated in turn increasing clearance and decreasing half life?
Thank you so much! You are helping thousands graduate and be contributing health professionals to society. This is big. My heart is grateful.
We love you prof. Zach❤️❤️❤️❤️❤️❤️
This guy is absolutely amazing !!!
You’re the best Zach! Thanks for this 🙏🏽
Big thank you to Prof Murphy and the team. I used the neurology playlist as a foundation for my part 1 residency exams in neurology. In addition to it I reviewed other topics covered on the channel. It was the best decision. I passed the exam and hopefully will start residency soon. My appreciation and respect to the team.
You are really gifted. I've been following your lectures since you started.
👍
Masha Allah I'm from Somalia🇸🇴 We proud of You Me and My friends For your Hardworking Thank you For Your Helping us With Out you I'm sure that i can't know something About Medicine.
Thank you.
I was literally trying to study this yesterday.. thank you so much for all your videos, they are genuinely life savers!
The first question (at 18:36) is actually really smart. Kidney disorders can either increase (e.g. glomerulonephritis, diabetic nephropathy) or decrease glomerular capillary permeability. But, if the condition was associated with increased clearance (increased glomerular capillary permeability), there would probably be no need for dialysis => there likely is decreased clearance.
Your videos are more effective than reading the medical books
Please upload more than one video at least 2 to 3 videos of pharma per week 🙏
We just started pharmacology course in school, this is the first video I'm watching on it and I am so happy because it has killed every single fear I had about pharm. Thank you ninja nerd
even tho this came up after my pharmacology exam, its so nice to see more pharma for another students!!!
Can you please do the rest of the pharmacology lessons this days please 🥺 .. I have exams after 2 weeks and your videos help a lot and facilitate the whole situation professor ! .. may Allah bless you and your beloved ones 🤍
Same here 🥺🙏
Yes me too
Me too
how did your exam go?
@@bala3136😂😂😂😂😂😂😂
You make every subject of medicine my favorite you are just magical sir, thanks a lot 🙏
You are delivering the most helpful and very educational material. Thank you on behalf of all! Let's support this channel by subscribing, liking, commenting! So worth!
I wish you were my teacher!! Thank you for all your help!
This video helped me to understand the topic which was always difficult for me. Thank you ninja nerd
Zack … your lectures are inspiring me to go back to school.
Wonderful! Where were you? When I was in Grad school?
Excellent! Just excellent!
Thanks for a very helpful lectures. 💕
Loving this series
Definitely here to watch...about ⌚
You are great teacher forever...one love from Tanzania
Thank you very much, I can see that you put a lot of passion into teaching these topics!
Zach you are really a hero.
You made this so much more clear than my professor! You rock :)
Thank you so much, love from India 😊😊
Thank you so much for helping us out on basic pharmacology
You’re magical prof: Zach Murphy ❤❤
Thank you for your time and effort
I don’t have tests or anything. I just find pharmacology very interesting.
Can't wait to see this but I'm now only in 2nd year 🤣😁
Please teach us dynamic,,cholinergic,adenergic also sir
Love from India 🇮🇳
I LOVE YOU NINJA NERD ❤️❤️❤️❤️❤️❤️
Thank you so much Zach❤️❤️
Please do the next video about Diabetes Drugs🙏🙏
This is so helpful!! thank you!!!!
Powerful lesson, kindly make videos on anasthetic drugs as well, kindly waiting
Thank you ninja nerd
We love you so much professor you are our life saving machine we do appreciate your wonderful work sir 🙏🙏
This is amazing ! Thank you soooo muchhhhhh you are the bestttttttt!❤❤❤❤❤
amazing as usual
Thankyou so much Nija Nerd!
Perfectly said and easy to understand
Thank you sir god bless you ❤❤
my bro Vmax making a comeback
you the best sir thanks for making us pass God bless you
Thank you Ninja nerd😭
Thank you so much, it is so helping
Timely!
Thanks a lot 🙏 💓 💗
Sir kindly teach the various compartment models of drugs as well
U r amazing sir
We r proud of u...sir. from pakistan
thanks sir
so helpful thank you!!!
Ninja is dope !
Great sir
Amazing!
Thank You soo much bruv!
Wow,,,,,,,,amazing
Never understand pharmacokinetics during my years at uni..u just clear my confusion on this...I will enroll if offer online pharmacology courses..keep up with good work 👏
Zack kindly Make a video on Etiopathogenesis and immunehistochemistry on lukemias and lymphomas .. These 2 topic Are so confusing While we Are diagonstic a patient
Have you done episodes on parasitic infection?
Regarding the first question, wouldn't undergoing dialysis compensate for the pharmacokinetic alterations of the drug caused by the renal impairment, eventually leading to no change in half-life and necessary dosage?
I swear I had the same thoughts but I also think it’ll depend on if the drug is dialyzable or Non dialyzable. Anyone with a better idea?
You are the best
Please are you going to do more videos about pharmacology
thank u
60 hours (t 1/2 = 5) would best approximate the half life of the Drug Ninja since over 96% of the drug is cleared. At 48 hours, roughly 94% of the drug is removed. How is 48 hours considered a steady state when that is less than 95%? Enjoyed the video, nonetheless!
C Is my answer
you are hero
you explain it like you were the one who discovered it, wow
"What the frig, kabaam, done roasted" 😉🙏 thanks zach and ninja nerd team
amazing
Launch for us more videos on parasympathomimetic sir ❤❤
May I know where can we find more exercises like in the video? Thanks !!!
I like the drug Ninja ......
I love all your videos! My educator in icu refers us to your videos, I use them for university, clear and detailed enough. Thank you so much! 🙏🙏🙏🙏 lifesaver hahah
Curious, are you NP or phd?
Launch for us more videos on parasympathomimetic sir
Hi Zach, I read in Lippincott that zero-order kinetics is non-linear, and first-order kinetics is linear. Can you confirm?
Zero-order kinetics is non-linear because the rate of elimination does not change proportionally with the drug concentration. As a result, small increases in dose can lead to disproportionate increases in drug concentration in the body.
• Example: Phenytoin and ethanol at high concentrations.
The whole comment section: Thanking zach for helping them with their studies.
Me who came to check how soon I can take a drug test. 😐
Why do some drugs follow zero order elimination?
Is it because of chemistry or other factors?
same question
why are zero order kinetics called non linear kinetics even though their graph is linear
Love❤❤❤❤❤❤
Thanks for the video, however, something needs to be cleared up here. if they say a drug follows nonlinear kinetics it means Zero order kinetics. some one may be confused by the explanation
Done.✅
"I got you boo"🤣❤
🔥🔥🔥
good
If she’s suffering from renal disease, doesn’t that mean that more of the drug will be eliminated in turn increasing clearance and decreasing half life?
I think for your question no 1 option B will be the right answer.
Zach education
14:45 when he says “rate of eliminationl” , put it on 1.25 and it’s gonna sound like Eminem in his song “I’m not a afraid”.
Crazy how I wanted to escape mathematics through medicine
Thannnnnnkksssss
👋
Ninja ur Cool af 😎💞
But isn't first-order kinetics called linear, and zero-order non-linear?
❤️❤️
Why You never gets angry,whatever a student does?😘
U should start a university bruh
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ily