Antiarrhythmic Drugs

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  • Опубликовано: 16 июл 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd.org/lecture/ant...
    @1:05:28 The alpha subunit Inhibits AC while the beta-gamma subunit activates potassium channels.
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Antiarrhythmic Drugs. We begin this lecture by reviewing Cardiac Physiology which will be essential in order to understand how these antiarrhythmics work. We will then go through the 5 types of Antiarrhythmic Drugs which include: Sodium Channel Blockers (Type I AAD), Beta Blockers (Type II AAD), Potassium Channel Blockers (Type III AAD), Calcium Channel Blockers (Type IV AAD), Adenosine + Digoxin (Type V AAD). After discussing these classes of drugs mechanism of action and indications, we will then transition into each of these types of drugs adverse reactions. We conclude this lecture by going over practice problems for Antiarrhythmic Drugs that we will be reviewing with you. We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:07 Antiarrhythmic Drugs (AAD) Introduction
    1:35 Cardiac Physiology
    49:37 Beta Blockers (Type II AAD)
    57:05 Calcium Channel Blockers (Type IV AAD)
    1:01:03 Adenosine + Digoxin (Type V AAD)
    1:14:06 Sodium Channel Blockers (Type I AAD)
    1:31:54 Potassium Channel Blockers (Type III AAD)
    1:42:33 Indications for Antiarrhythmic Drugs
    2:02:04 Adverse Drug Reactions: Beta Blockers (Type II AAD)
    2:07:42 Adverse Drug Reactions: Calcium Channel Blockers (Type II AAD)
    2:09:42 Adverse Drug Reactions: Adenosine (Type V AAD)
    2:12:47 Adverse Drug Reactions: Digoxin (Type V AAD)
    2:20:10 Adverse Drug Reactions: Sodium Channel Blockers (Type I AAD)
    2:27:26 Adverse Drug Reactions: Potassium Channel Blockers (Type III AAD)
    2:33:36 Antiarrhythmic Drugs Practice Problems
    2:40:25 Comment, Like, SUBSCRIBE!
    Pharmacology Source:
    Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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Комментарии • 276

  • @zeebalz7038
    @zeebalz7038 Год назад +89

    You made this 5 days to my Pharmacology exams. You're a G

    • @Stanleeeeeee
      @Stanleeeeeee 3 месяца назад +1

      Mine is tomorrow 😭😭

  • @fanzone59
    @fanzone59 Год назад +66

    Almost 3 hours of a video= hard work= tremendously helpful and valuable information being given, thank you!

  • @joelfernandez3408
    @joelfernandez3408 Год назад +36

    This is hands down the best pharmacology/physiology channel on RUclips , thank you so much for making these Videos and keep them up!

  • @tosanetsano2070
    @tosanetsano2070 Год назад +73

    I was literally just taught this topic this morning in my pharmacology class. Thank you for all you do, you guys have been a tremendous help in getting me this far in pharmacy school🙇🏾‍♀️🙇🏾‍♀️❤️

    • @veenapriyadarsini
      @veenapriyadarsini Год назад

      I taught this topic to my students this mrng,i learn more from ur explanation

  • @shrutikaldhone8710
    @shrutikaldhone8710 Год назад +36

    Your lectures help to clear the concepts about the particular subject.... our vision becomes crystal clear. No matter how many times I read antiarrhythmics, I used to get confused and frustrated. But hey, after watching this full video, I feel a lot confident about the topic now!! I really admire the efforts you guys put in to teach the subject. And I adore your capability to learn, understand and then teach any topic that you present. I am following you since a year now, and not a single lecture was there where I got bored or neglected the teacher 😉. You have the mesmerizing capacity to keep your audience glued to your lecture till the very end, and very few people in the world harbor this captivating ability... you stimulate me to study hard and harder. I can't thank you enough. Love you guys! Be blessed always. And keep teaching!!!

  • @VincentAubin-qz6kp
    @VincentAubin-qz6kp 3 месяца назад +5

    I've never seen a better description on the pharmacodynamics of the drugs and ways to remember them; perfect video for cramming for a test lol

  • @piyapatel3193
    @piyapatel3193 Год назад +8

    The excitement and enthusiasm to know this, rubs off!! Hats off to him🙌

  • @tanzeelakakroo9624
    @tanzeelakakroo9624 9 месяцев назад +4

    Hands down the best channel to ace any concept regarding any physiological concept . Can't believe u taught Arrythmias so well that no teacher or any other video on RUclips could have done
    "Thanks for existing Zach "❤

  • @sofiaperan4670
    @sofiaperan4670 Месяц назад +2

    literally the best teacher in the world.

  • @gabbygtz7801
    @gabbygtz7801 Год назад +9

    Congrats on 2m!!🥳🎉 u guys more than deserve it! from the bottom of my heart, thank you Zach and team for everything that you do! idk how I would be getting through PA school without ur help! Ninja nerd for life:)

  • @Cole-mb8dn
    @Cole-mb8dn Год назад +6

    This video is exactly what I needed for pharmacology rn! Crazy how Ninja Nerd just knows.

  • @nghiapham1644
    @nghiapham1644 Год назад +4

    This is GOLD! Your enthusiasm is palpable! Thank you very much!

  • @doskevin4882
    @doskevin4882 20 дней назад +1

    Quick tip to help you understand better:
    Inside of cell is more negative than outside of cell AT REST. This means they are polar. Opposite charges (the old saying polar opposites). When a cell depolarizes (de=not) the inside of the cell is becoming more positive meaning they are becoming less polar. When the cell depolarizes (re= again), it is becoming negative again back to the resting state of the cell.

  • @goseepy
    @goseepy Год назад +1

    Can't thank you enough for these easy-to-follow lectures. So many future patients will benefit from this knowledge.

  • @johnerskine9792
    @johnerskine9792 Год назад +3

    this is actually fantastic. It is genuine practical explanation and relevance to clinicians. It isnt regurgitating a textbook and you've really thought about how to teach. great work

  • @devrajlamichhane4499
    @devrajlamichhane4499 4 месяца назад +1

    This is the best description and way of teaching Cardiac physiology and arrhythmias..... Thank you Doctor for Hard-work.

  • @errrccc
    @errrccc 9 месяцев назад +1

    This just cleared a lot of my confusion about anti-arrhythmic drugs. Definitely worth to watch! Thank you so much!

  • @abdullahniaz7743
    @abdullahniaz7743 2 дня назад

    The very precious human being on the earth Ninja Nerd the great. Salute to ur way of delivering lecture.

  • @linaziad8914
    @linaziad8914 Год назад +3

    No words can describe my appreciation to you and your team thank you so much your videos are life saving thank you for all your effort

  • @user-pk5xp2ln5q
    @user-pk5xp2ln5q 11 месяцев назад +1

    I seriously don't know what i would do without your classes.

  • @felixquenneville981
    @felixquenneville981 Год назад +1

    As usual, you make a complex subject crystal clear! Sure your videos are longer than most, but it is so worth it!

  • @timothykruse8236
    @timothykruse8236 3 месяца назад

    I appreciate your videos. I'm a firefighter/Medic and I watch your videos periodically as a refresher. Your take on physiology and the way you teach fits my learning style perfectly.

  • @amandavitaglian5859
    @amandavitaglian5859 Год назад +2

    You explain these topics so well! SO helpful

  • @1998elif
    @1998elif 10 месяцев назад

    Im already finished with medschool but i still refresh with your videos.. amazing work thank you!!

  • @suboptimalzebra9284
    @suboptimalzebra9284 Год назад

    Great lecture; about to start ACP school and this helped a ton. Huge thank you; well worth the time!

  • @doc599
    @doc599 Год назад +1

    Besttttt lecture on RUclips i have watched alott of lectures but i didn't understand....it was sooo confusing topic but you made it look sooo simplee..... thank u zack❤

  • @IreneHeeney
    @IreneHeeney 6 месяцев назад

    Fantastic lecture! Thank you! I'm a pharmacist, and your lectures are my go-to for CPD

  • @lyuboslavlichev6454
    @lyuboslavlichev6454 6 месяцев назад

    Honestly , one of his best lectures . Amazing

  • @remolabarca4959
    @remolabarca4959 Год назад +4

    Awesome lesson as always....thank you all

  • @eyobtefera3210
    @eyobtefera3210 Год назад

    Hands down for this bewildering video. THANKS

  • @fightersoul6436
    @fightersoul6436 Год назад +1

    I can take only professor zach's classes continuously for hours, without losing focus for a min.... ✨✨✨...

  • @umurbatmaz9724
    @umurbatmaz9724 5 месяцев назад

    I love how you explean it with passion. Thanks man!

  • @linagudauskiene48
    @linagudauskiene48 Год назад

    The best teacher with the best teaching method l have ever seen

  • @physiokhankhan4729
    @physiokhankhan4729 Год назад +1

    You are great sir your lectures can make my concept really clear and i like the way that you teach to us
    Best wishes to you ✌❤

  • @nonamohemmed1129
    @nonamohemmed1129 Год назад +2

    Dude it's like you knew that I need this 😭😭😭😭😭
    Thanks ❤️❤️

  • @naziazazay1558
    @naziazazay1558 Год назад +6

    Your lectures are really informative Can you please make videos on pharmacology of other systems too? Thank you.

  • @mahfoudsmedicine8230
    @mahfoudsmedicine8230 Год назад +3

    I was waiting for this video, nothing to say but, you're the best.

  • @Seda1979
    @Seda1979 Год назад +1

    Good lecture Doc. I will say as someone who has taken both flecainide and currently propafenone this was very informative. HOWEVER, with propafenone it does have a minimum beta blockade effect as well. Grant it, it's not major but it's worth mentioning in full disclosure. I take propafenone for symptomatic pvcs, although now I am taking it post ablation,( which I had on March 17th this year while my heart recovers). Flecainide is a good drug, but it ran its course with me, (after 4yrs). I am 44yrs old. I thank GOD for my electrophysiologist who switched me from ditilazem to flecainide when he did. He is the same one who just did my cardiac ablation. NOTE: I had wpw, but that was ablated in 99 while I was a soldier at the young age of 20. Much of my pvcs came from that residual scar tissue from that first ablation. I hope and pray that I am done with ablations for the rest of my existence. GOD Bless.

  • @jakewong6943
    @jakewong6943 8 месяцев назад

    You are the best!! Thank you for these high quality and incredibly engaging videos. Always makes my day :)

  • @francescaitta4775
    @francescaitta4775 10 месяцев назад

    Thank you for this Masterful explanation! I have no words to say but Thank You

  • @RA-om8ck
    @RA-om8ck 11 месяцев назад

    Thank you Zach for your dedication and passion. I love details and you are a master in that! I always tell my class that if you want to get by learn the concepts, but if you want to make a difference or discover something learn the details. Hey I just discovered something - Double Quarter Pounder with Lecture and Fries Please. Mnemonic to remember the class I antiarrhythmic drugs. I love it!

  • @veronikakirienko4807
    @veronikakirienko4807 Год назад

    Great video with lots of information. Thank you!

  • @MemeMania001
    @MemeMania001 Месяц назад

    Your approach to this topic is a gem 💎

  • @franciscofierro758
    @franciscofierro758 3 месяца назад

    This is one of the most life saving videos I've ever seen. I'm gona donate something beceause this is better than paid stuff and its free. This channels and all the team are the best!!! Really gratefull.

  • @ehe3653
    @ehe3653 5 месяцев назад

    Thank you so much for this! the questions at the end is really fun to answer after studying

  • @inalaura9292
    @inalaura9292 Год назад

    Thank you for your lectures. We would like to see and hear clearer the names of drugs you are taking about. Best wishes from patients. 💐

  • @SamanPiroti
    @SamanPiroti 6 месяцев назад

    this lecture was amazing thank you so much Zach!

  • @learnplex4914
    @learnplex4914 9 месяцев назад

    Beautiful Explanation. Just Loved It❤️ You always make textbook reading very simple.

  • @Drqazi247
    @Drqazi247 Год назад

    super helpful!! I was going to teach this topic. This is Exactly the video I was looking for ❤️

  • @ryancottrell3609
    @ryancottrell3609 Год назад +1

    This is so helpful, thank you.

  • @sakshidahiya6802
    @sakshidahiya6802 Месяц назад

    you are amazing thanks for you great hardwork,you explain everything from scratch.your channel is best

  • @ametrinepatt
    @ametrinepatt Год назад +1

    I don't take pharmacology but love listening to your voice before class, calms my anxiety 😅

  • @evgeniyamiller4503
    @evgeniyamiller4503 9 месяцев назад

    Outstanding work! Thank you!

  • @user-zk1wo2wx4p
    @user-zk1wo2wx4p Год назад

    thank you so much Zach I was waiting for this video

  • @user-te3tk7jr9t
    @user-te3tk7jr9t 9 месяцев назад

    Thank you very much for all the help. ❤

  • @dastanmirzambetov6191
    @dastanmirzambetov6191 Год назад

    Your help made me interested in medicine more than before

  • @longoan7895
    @longoan7895 Год назад +1

    thank you for the lesson, sir! I hope there are more video of cardiology

  • @Thibxngwana
    @Thibxngwana 21 день назад

    You are an amazing teacher. Thank you so much

  • @andreatobartorres985
    @andreatobartorres985 2 месяца назад

    Amazing unique FANTASTIC VIDEO FOR ANTIARRITMYCS FOR MY STEP 1 thank you so much

  • @peterbarnabaskovacs7226
    @peterbarnabaskovacs7226 10 месяцев назад +1

    Protect this man at all costs!

  • @DavidTiptonJr
    @DavidTiptonJr Год назад +1

    Thanks for the content!

  • @dorian_arno
    @dorian_arno Год назад +3

    Can you kindly discuss the Anti-cancer Drugs? Btw I have my Biochemistry VIVA next week. All your Physiology videos helped me a lot. Thanks.😊

  • @HAIDERALI-he9fh
    @HAIDERALI-he9fh 2 дня назад

    Thank you for providing great concepts 🙂

  • @meimei9057
    @meimei9057 Год назад +1

    Thank you dear!Nice explantion!

  • @ilariaachillea
    @ilariaachillea Месяц назад

    all this useful knowledge for free, thank u so much

  • @makeupgroupiesofficial4434
    @makeupgroupiesofficial4434 6 месяцев назад

    EXCELLENT, EXCELLENT - THANKN YOU! I just became a member to download all the goods!

  • @akifgunay6650
    @akifgunay6650 Год назад +1

    great video, tremendous work.

  • @flowers44444444
    @flowers44444444 Год назад

    Your videos are very helpful thank you soooo much please continue presenting helpful videos 😊

  • @ughsirius
    @ughsirius Год назад

    THANK YOU SOOOO MUCH ZACH!!! YOU'RE THE BESTTT

  • @MyLe-xy1un
    @MyLe-xy1un 4 месяца назад

    I am learning so much, thank you good Sir.

  • @wt8965
    @wt8965 7 месяцев назад

    Thanks for the explanation god sent

  • @warwar5380
    @warwar5380 Год назад

    love your devotion

  • @hasanmustafa915
    @hasanmustafa915 Год назад

    Great video great explanation thank you for your effort 👍

  • @AadilKhan-mb5ic
    @AadilKhan-mb5ic Год назад +1

    Outstanding ❤

  • @yachiapatel
    @yachiapatel Год назад +6

    Can't be blessed enough to be born in the era where we have You 🌠🧿. You are our true Ninja, who just support and help us achieve our goals that too with ease. People with ninja nerd family always ask for more n more blessings for you Mr. Zach and may God shower all the love, gratitude and success to you 🥰🙌🎊
    And "as always until next time".💕

  • @ScottSchellhammer
    @ScottSchellhammer 2 месяца назад

    Micturition reflex. Do not forget the muscarinic cholinergic effect on m2 receptors of internal urethral sphincter to relax it from S2S3S4 intermediate zone lamina 7 thru pelvic plexus to urinate. Thank you very much
    2:19

  • @g.kgadri6655
    @g.kgadri6655 6 месяцев назад +1

    Guys, YOU ARE AWESOME.... IT IS ALL COMING TOGETHER NOW...!!!!!

  • @tamngoc6046
    @tamngoc6046 3 месяца назад

    Thank you very much Ninja Nerd

  • @chandanamedi3570
    @chandanamedi3570 Год назад +1

    Thank you very much ❤

  • @noornoora688
    @noornoora688 Год назад

    So helpful, thank you so much

  • @waris17
    @waris17 6 месяцев назад

    Just love your work man

  • @mosesibeabuchi6455
    @mosesibeabuchi6455 10 месяцев назад

    Thank you ninja you're a blessing.

  • @temidayoademokoya7572
    @temidayoademokoya7572 Месяц назад

    Love this video!!!

  • @Rasha.Ishtar
    @Rasha.Ishtar 7 месяцев назад

    Thank you Zach you are the best ❤

  • @Prismatic_rehaam
    @Prismatic_rehaam 9 месяцев назад

    U are a great person, great teacher with so much positivity. U are amazing. may Allah Almighty gives u more strength, power and fulfill all of your wishes . Great respect and love ❤

  • @roronoazoro3204
    @roronoazoro3204 Год назад

    Ninja nerds videos are the only videos that I like before I even watch the video

  • @johneid6242
    @johneid6242 Год назад +1

    i freaking love this man

  • @doskevin4882
    @doskevin4882 5 дней назад

    Bought the membership. Worth it for sure

  • @emmanuelelijah3133
    @emmanuelelijah3133 Год назад

    Wow I was thought this topic today in the afternoon in med school, I'm preparing to write pharmacology test by end of this month. I pray I pass coz there are lots of things to know like drugs and mechanism

  • @medicallyenhanced
    @medicallyenhanced Год назад

    thanks for all you do.

  • @admeliora3962
    @admeliora3962 8 месяцев назад

    i heckin' love prof. zach

  • @amiliashibu1875
    @amiliashibu1875 Год назад +1

    Thanks!

  • @rishiraj2548
    @rishiraj2548 Год назад +3

    2M+ subscribers!!! Achieved!!!👍

  • @evolvedone3493
    @evolvedone3493 Год назад +3

    Congrats on 2M I wish I could donate you but I will surely in future 👏👍🏻

  • @user-jf6jd7ls2g
    @user-jf6jd7ls2g 3 месяца назад

    I relly like the way you explain it, keep it up bro

  • @jben246
    @jben246 9 месяцев назад

    amazing lectures

  • @chrischologitas2409
    @chrischologitas2409 Год назад

    My god this is so well thought well done sir

  • @bdreamy1807
    @bdreamy1807 Год назад

    Brilliant dear Zach

  • @waqassalishah4102
    @waqassalishah4102 Год назад

    Thank you 🤗 appreciated
    Tomorrow that's our topic

  • @meghapatel1683
    @meghapatel1683 5 месяцев назад

    Thank you so much!!❤