Michaelis Menten and Lineweaver Burk plots

[@RLL-404]

Thank you very much. I've watched several videos on the subject of lineweaver-burk plots, yet you are the first one that actually tells me how to fill in the graph by translating the [S] and V into 1/[S] and 1/[V]. I had a hunch that this would be the answer, but no examples. Greetings from the Netherlands

[@julietmbah3684]

This lecture is so straight to the point thank you ma'am

[@GabrGo]

It's been a week trying to study this and finally found someone that explained it flawlessly!
Truly Thank you!

[@emabro9]

This is the best explanation on RUclips for this!!! 🎉❤

[@wakandastore9625]

Best video on this topic! I have so many places and I understood nothing, thank God I found you, my exam is tomorrow and definitely this question will be there. So you have helped me to get closer to a Distinction in BSc Chemistry

[@brightonmudenda440]

I''ve been struggling for weeks to understand this. thanks for this video. very helpful.. :)

[@JhonCrocker]

You can explain very very well sussanah. Keep up your great work❤
Thank you so much

[@fennamadison341]

so helpful! really clear explanation, much better than my lecturers explanations.

[@lilybrady5635]

this was so helpful, saved me for my midsem

[@varunbhanushali6751]

You earned a subscriber here, Explained very nicely💯😊

[@topeoluwafemi2773]

Ma'am could you please explain how dissociation constant can be gotten from the graphs?

[@vijayaki]

Nice lecture but a small query: at 11:01 through 12:39 do you mean cell does not inhibit malic enzyme........As can be seen from the M-M curve aspartate increased the malic enzyme activity (isn't it non-inhibiting?). But, what you are saying from 11:01 to last, negates all about the aspartate activity.......Did I miss something? I wish to know if I am correct or wrong. Now I am more confused.

[@susannahhannaford353]

You are right. Aspartate is an activator and speeds up the rxn.I did mispeak there. Specifially -- the text at the top of the page at 11:25 should read, why would the cell want to activate malic enzyme when there is lots of aspartate.
As far as why... we normally think about the TCA cycle as a simple cycle without the off/ on ramps that allow the cell to feed other substrates into the cycle and to take out intermediates to use for other rxns.
If the cell has plenty of aspartate, then it can convert that aspartate into oxaloacetate and keep the TCA cycle running. That means the cell is free to redirect some of its malate in the side rxn catalazyed by malic enzyme. For example, the resulting pyruvate can be converted into several small amino acids (e.g., alanine) or used for other anabolic pathways.

[@vijayaki]

I like the way you simplyfied the whole L-B plot..
Great stuff in a short video.
Was potent and soundly put
It had everything in a nutshell
Kudos I appreciate your efforts and enthusiasm
Best
Vijay

[@talashpeygir2621]

I learned a lot. Appreciated a lot.

[@Kobs.A]

I love you, thank you so much

[@oluwolefemi5862]

Thanks for this lesson

[@sesethuhotele695]

Thank you 🙏

[@MugoMucangi]

wow turns out its so simple

[@itsme_poku]

Thank you very much! This lecture was very helpful.

[@benysmart1643]

Thank you very much

[@coreywhatareyoudoinghere6065]

Thank you so much my professor made this concept so difficult to understand

[@muzamilnazir624]

Very helpful..

[@jacintaobiefule1200]

Thanks very much

[@PempheroSikumbiri-cn5qf]

Very effective 🎉

[@joshuadavid2783]

👍👍👍👍 Thankssss

[@depressotiredo]

so fuckin helpful

[@julietmbah3684]

This lecture is so straight to the point thank you ma'am