Видео

The first of a series of videos on brain development. This video introduces the topic broadly, discussing why we study neural development, introducing some common model systems, and outlining some of the steps involved in brain development.

Synaptic Vesicle Release

Glutaminergic synapses

Post-translational sorting to the Nucleus

A brief overview of post-translational sorting mechanisms, followed by a look at how most mitochondrial proteins are targeted to that organelle.

Synapses and Neurotransmitters: The Basics

A look at the pathways that carry gustatory information into the brain. We look at the key brain structures, their functions, and finish by looking at modulation of the pathways using input from other sensory modalities as well as based on experience.

Gustation 1 peripheral receptors

The video begins with an overview of the role of insulin in regulating blood sugar levels. Then it reviews the structure and activation of the insulin receptor, and the IRS-PI3K-Akt pathway. It shows how Akt can lead to insertion of GLUT4 vesicles into membranes, and then looks at the metabolic actions in liver and fat cells.

MAP Kinase Ras Raf Mek Erk signaling

GPCR Gai pathway

This video walks through the GPCR, G alpha s, adenylate cyclase signaling pathway. It examines the cellular events for each step. The video concludes with a look at how the pathway is inactivated and the role of arrestins in cell signaling.

A walk-through the g protein coupled IP3 DAG pathway. This is one of the common GPCR linked signaling pathways, and the video illustrates each of the players: how GPCRs activate Galpha subunits; how Galpha activates phospholipase C (PLC), how IP3 and DAG are produced, and their targets in the cell. Video includes two examples of this pathway is specific cell types degranulation of mast cells an...

Microfilaments: structure and function

Intermediate Filaments

Cytoskeleton introduction

Fermentation

Michaelis Menten and Lineweaver Burk plots

Electron transport chain and ATP synthase

Pyruvate oxidation and the TCA cycle

Mitochondria

Metabolism 3 regulating glycolysis

cellular metabolism 2

Cellular metabolism 1

action potential 1

Hypothalamic Pituitary Axis

Hormones overview and introduction

Hypothalamus

Somatosensory cortex organization and function