Sir Thank you so much for this video. This helped me lot while I was confiused with biochemistry examination. Thank you agin and again.we need more videos♥️
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Many thanks for your amazing explanation, no one explained it as you did , would you pls allow a transcript to show below the video for more focus , thank you
I have a quick question; if the alpha subunit has ATPase activity, what prevents the conversion of ATP to ADP before it can activate the Adenylyl Cyclase?
Hummm... Interesting question. Honestly I don't know the answer. It may be the association with the receptor itself or with beta-gamma complex. Or maybe the activity is intrinsically slower than the speed with which it goes to Adenylyl cyclase and activates it. But as a medical person we don't need further detail to understand other concepts. I have already covered every detail necessary to the best of my knowledge and understanding. So although the question is interesting, I am not excited to find out the answer. I am happy with my assumption 😝
Sir with the effect of adrenaline and noradrenaline the calcium ions will come out from sarcoplasmic reticul into the cytosol but u just said that it sequesters the ca2+ions into the sarcoplasmic reticulum
Yes, both statements are true. There is no conflict between the two. Under the influence of these hormones the SER becomes more loaded with calcium i.e. more Ca is sequestered in SER. This is at the basal level. And as this sequestered Ca is released during each impulse, more Ca is released. And this, as stated is during impulse. I hope it helps
Instead of mnemonics, I try to explain the core concept in a memorable way. You can consider visual metaphors as memory tricks. That being said, I do get thoughts of making mnemonics but if I ever do that, it will be secondary to my main way of teaching.
Literally the best video to knw how actually this G protein couples receptors work.. no need to see other videos on ths topic..thanks a dozen
Most welcome. Please share the channel with yours contacts to support us. Thank you. 😊
You made medical concepts easier to understand. More powers to you sir.
Thanx from Iraq 🇮🇶
Pharmacy student
I'm stunned how didactic this video is ! Amazing ! Keep the good job dude, I appreciate your effort !
Yes I will. Thank you 😊
Thankyou for the detailed explanation. The animated video made it even more fun to watch and understand better
Sir Thank you so much for this video. This helped me lot while I was confiused with biochemistry examination. Thank you agin and again.we need more videos♥️
Your videos are really easy to understand, interesting and helpful. Thank you so much for making such amazing videos🤩
Outstanding work 👍👍
so well explained, we can't thank you enough!
Great explain about g protein coupled receptors😊😊😊. Thanks sir
simple yet effective explanation. thank you
🤩 I am going to in love with your lecture
Thank you so much this video is so helpful for me to understand the physiology 🧡🔥
Fantastic illustrations and explanation
راجع جدا ❤ شكرا لك
this is amazing you made it very simple and understandable
thanks for your efforts
Thank you so very much, sir. You've helped me to understand this concept really well
Clear and practical video, thank you so much
Welcome 🤗
Thank you, very well explained and had nice animations :)
Thank you what a animation keep doing sir
Amazingly helpful. Thank you so much~
Sir we need more and more Vedios like this tq so much sir
Yes. I am working on it
@@NonstopNeuron 👍
So interesting sir
Underrated channel.
I need your support to grow. If you feel this channel deserves more, please share videos to all your contacts.It helps a lot in many ways. Thank you so much.
Amazing 😍
Mashaallah
Your illustrations are sooo cute🤣🤗🤗
I wanted this concept, thanks 🙏😇
Many thanks for your amazing explanation, no one explained it as you did , would you pls allow a transcript to show below the video for more focus , thank you
Captions are added to almost all the videos on the channel. You can turn them on or off as per your preference.
❤❤very interesting
Brilliant 👏🏻
Awesome ❤ most helpful
It's amazing 👏
Thanks so much
Amazing!!!!
Thanks for sharing. Its wonderful video
Thank you!
💖💖superb sir
Nice! I like the explanation
Really it's very good 😃😻
Very usefull lecture And very cleanly explained Thank u sir😍
I have a quick question; if the alpha subunit has ATPase activity, what prevents the conversion of ATP to ADP before it can activate the Adenylyl Cyclase?
Hummm... Interesting question. Honestly I don't know the answer. It may be the association with the receptor itself or with beta-gamma complex. Or maybe the activity is intrinsically slower than the speed with which it goes to Adenylyl cyclase and activates it. But as a medical person we don't need further detail to understand other concepts. I have already covered every detail necessary to the best of my knowledge and understanding. So although the question is interesting, I am not excited to find out the answer. I am happy with my assumption 😝
I am also assuming that you are a medical student. If you are a researcher or something, then you might need to go into further detail.
thank you so much my dear god...teach us more
absolutely amazing video!!!
Amazing video
Awesome!!!
Clear understanding ❤
Very well made👏
Wow amazing
Thank u so much sir.....👏
excellent explanation!!! thank you so much!!
Thank you so much.
Nice work
Thank you, so much !
how does sequstation of Ca into the sER cause increase in myocyte contractility? isn't it the opposite?
With sequestration more calcium can be released in cytosol with each impulse. So the contractility increases
Best💯🙂↕️
Superb
Thanks😊
Thank you
Thank you so much sir.
Most welcome
Sir with the effect of adrenaline and noradrenaline the calcium ions will come out from sarcoplasmic reticul into the cytosol but u just said that it sequesters the ca2+ions into the sarcoplasmic reticulum
Yes, both statements are true. There is no conflict between the two. Under the influence of these hormones the SER becomes more loaded with calcium i.e. more Ca is sequestered in SER. This is at the basal level. And as this sequestered Ca is released during each impulse, more Ca is released. And this, as stated is during impulse. I hope it helps
Thanks a lot
❤📚thanks
Very helpful
Thank you so much for made easy 😁...
It really helped me a lot
Thnq u sir ❤️
Very very useful❤️
Glad it was helpful!
Sir,small request - Plz make pnemonics to remember drugs🙏🙏
Instead of mnemonics, I try to explain the core concept in a memorable way. You can consider visual metaphors as memory tricks. That being said, I do get thoughts of making mnemonics but if I ever do that, it will be secondary to my main way of teaching.
Good video!
Thank you
Thank you thank you
thx u smmm
Well communicated
Beta gamma subhunit remain attached to gprotein?
No
@@NonstopNeuron okay and one more dobut why receptor use more than one g protein?
To integrate incoming signals. Watch this video: ruclips.net/video/aIZQ3ker0KE/видео.html
You will get the idea.
@@NonstopNeuron okay thanks
رائع جدا شكرا جزيلا لك
💗💗💗
❣️
How :0
Thank you