The Cell Cycle and its Regulation

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  • Опубликовано: 13 янв 2025

Комментарии • 158

  • @jarednicholas3180
    @jarednicholas3180 7 лет назад +343

    I am a tutor in physiology, physics, chemistry, and mathematics, and I must say you have a very special way of breaking down the information in a comprehensible, sequential manner that is just really enjoyable to hear and watch. You are definitely helping a lot of people with your linear, step-by-step methods. I've always been fond of cell signaling pathways and understanding them from start to finish. Very well organized!

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад +45

      thanks very much!

    • @Zetsuke4
      @Zetsuke4 4 года назад +3

      Jared Nicholas Really. what physiology do you teach? cell biology?

    • @jherlennemaeatupan7055
      @jherlennemaeatupan7055 4 года назад +1

      I agree. easy to understand. Good job Professor Dave. I'm also a Science Teacher.

    • @faridsaid9180
      @faridsaid9180 3 года назад

      @@ProfessorDaveExplainswhich type of cells? Just asking am not medical profession. Is it stem cells or lymphocytes?

    • @bernardkamau7017
      @bernardkamau7017 3 года назад

      @@Zetsuke4 aaa

  • @nitamac1312
    @nitamac1312 7 лет назад +89

    THANK YOOOOOOU. I looked everywhere for a decent video that explains this stuff! This video is clean and not a jumbled and crazy. PLEASE DONT STOP MAKING VIDEOS THEY'RE TOO GOOD!

  • @imanalkole919
    @imanalkole919 5 лет назад +34

    You need an award, sir! You are really helping me out understanding this on a basic level!

  • @mandabutangry1146
    @mandabutangry1146 5 лет назад +11

    I've been struggling in class to understand the checkpoints and have had no luck in finding videos that explain how it works. I greatly appreciate your help and finally have a sense as to what is going on!

  • @tella5357
    @tella5357 4 года назад +6

    Professor Dave is lit af man. I look at this channel for all my college classes. The way he explains is extraordinary.

  • @aquila6668
    @aquila6668 4 года назад +5

    This is what I always want from a discussion, there are always new trivias/facts added and goes beyond the surface of the lesson (defining terms, explaining what is already in the ppt, and whatnot).

  • @Asparagus-T
    @Asparagus-T 3 года назад +3

    Quick question-
    Chromosomes can be monads (a single chromatid) or dyads (sister chromatids held together by a centromere; a dyad has two identical strands of DNA held closely together in a location called the centromere). When a cell is in the G1 or Gap 1 Phase of their cell cycle, the nucleus contains monads but during the S phase the DNA is synthesized into the dyads that are seen in the G2 or Gap 2 phase.
    *The strands are identical assuming that no copying errors (mutations) have occurred during the S phase of the cell cycle
    Familiarize yourself with the conditions of a cell’s chromosomes during the G1 and G2 phases of the cell cycle.
    The 4 phases of mitosis:
    Prophase = chromosomes condense
    Metaphase = chromosomes line up in the middle of the cell with reference to the two poles (the equatorial plate or metaphase plate) with each chromosome on its own spindle fiber (by itself)
    Anaphase = separation of the chromosomes
    Telophase = formation of two nuclear envelopes around the two chromosomal clusters and then the cell divides (cytokinesis)
    Questions:
    In humans, there are 46 chromosomes in the nucleus of a cell. When the cells are in the G1 phase the 46 chromosomes are 46 monads which are 46 single chromatids. During the S Phase the 46 monads become 46 dyads which are 46 sister chromatids that will split during the M Phase/Mitosis. What is in the nucleus of the cell after mitosis?

  • @angiereneewellness6227
    @angiereneewellness6227 2 года назад +8

    Your videos are incredible and break down the most complex concepts into a step-by-step, comprehensive way. You are absolutely saving me in my biology course! Thank you!

  • @farhanahmed2508
    @farhanahmed2508 7 лет назад +47

    I am astonished by how you explained it so well. Well done...

    • @abdeljalilpr2033
      @abdeljalilpr2033 7 лет назад +3

      Farhan Ahmed yes i wish if it was in arabic bt this is good too

  • @Shub_inc
    @Shub_inc 5 лет назад +16

    Nicely explained Dave sir!
    You deserve more subscribers.
    I hope you will get at least 10M subscribers.
    Love from India

  • @lukamtc9188
    @lukamtc9188 8 месяцев назад +1

    its reassuring to see that the numbers in my textbook line up perfectly with the examples you give. you are quite literally on the same page.

  • @samjohn2984
    @samjohn2984 10 месяцев назад

    Your method of teaching and breaking down concepts is absolutely remarkable. I am a chemistry teacher and my school required me to teach biology and learning from your videos has literally taught me the whole course in a few simple videos😅. Remarkable explanation. Please keep up the good work.

  • @OtonashiIo
    @OtonashiIo 2 года назад +4

    Man I gotta love that iconic intro

  • @CrispyApplJackz
    @CrispyApplJackz Год назад

    I LOVE THIS TYPE OF CONTENT. THANK YOU. HIGH SCHOOL ALL OVER AGAIN BUT THIS TIME I'M FOCUSED AND INTERESTED.

  • @nickmachado-mejia578
    @nickmachado-mejia578 2 года назад +24

    thank you biology jesus

  • @gracedemalona9197
    @gracedemalona9197 7 лет назад +8

    You are fantastic! As simple as that! I can always go watch your videos, when I need 'the quick and dirty' version of a whole semester, I struggled understanding! And then so many things fall into place! Thank you Dave!

  • @sserwaddaderrick1523
    @sserwaddaderrick1523 Год назад +1

    I’m a first year student of molecular biology! Thank you professor 👨‍🏫

  • @john-paulchidili2327
    @john-paulchidili2327 Год назад

    This is remarkably impressive... Prof Dave, you have a unique talent of deconstructing complex subjects. WOW!

  • @aramhakobyan8549
    @aramhakobyan8549 2 года назад +3

    An excellent tutor with an excellent explaining skills. Thank you very much indeed for your tutorial videos Professor Dave!

  • @amanyasharon5227
    @amanyasharon5227 6 лет назад +5

    Well done Dave, this is a great presentation

  • @Genaralgear5
    @Genaralgear5 2 месяца назад

    Thank you I was worried I didn’t under stand how to do these and I was rushing to study and this helped a lot thank you

  • @davidkissser8011
    @davidkissser8011 7 лет назад +13

    you are great, thank you Dave!

  • @KingMB_XJ_Official
    @KingMB_XJ_Official Год назад +2

    In school, we watch the explanation videos. At home, I watch the debate videos.

  • @pastimepursuit7212
    @pastimepursuit7212 3 года назад +1

    5:00, 5:20, 5:52, 6:40!, 6:50!, 7:22!, 7:40!, 8:35, 9:44, 10:25, 10:51!, 11:08!

  • @randomarun2950
    @randomarun2950 7 лет назад +3

    This helped a little on the subject, thanks. I even learned some extra information!

  • @rhemaray-mbata8588
    @rhemaray-mbata8588 3 года назад +1

    you are saving my life right now thank youuuu

  • @reeleltahir8479
    @reeleltahir8479 3 года назад

    İ wish to have you in my collage dude, i didn't just learn, i enjoyed it

  • @jenniferblears192
    @jenniferblears192 5 лет назад +3

    Video saved for my upcoming January exam!! Love you.

  • @AxelZaore
    @AxelZaore 6 лет назад +2

    This is indredibly great explained. Thank you so much!

  • @rachel.258
    @rachel.258 5 лет назад +2

    You deserve way more subscribers

  • @heltiswelt
    @heltiswelt 2 года назад

    I really appreciate your tutorials, it helps me a lot. You deserve an award, Sir.

  • @risnelcopio2891
    @risnelcopio2891 2 года назад

    Thank you so much for this....now clearly understood...I can now prepare my presentation☺️...God bless🙏

  • @abigailwatson3330
    @abigailwatson3330 2 года назад +1

    At this point its not my degree, its our degree!
    thanks for the content as always!!

  • @nipunipoornima8902
    @nipunipoornima8902 4 года назад +3

    Well explained, understandable and clear... Thank you prof. All your videos are very useful. I've been watching all of them.

  • @embryophytelove
    @embryophytelove 5 лет назад +1

    Good tutorial as always, Dave!

  • @ThePetra136
    @ThePetra136 6 лет назад +1

    this is great video! really helped me understanding cell cycle regulation! thanks!

  • @somasundram2975
    @somasundram2975 3 года назад

    Please make videos with more explanation ....request. Your videos are best .

  • @holistic-honey
    @holistic-honey 3 года назад +2

    @dave So Cyclins and kinases provide the signal to help the cell move along through the checkpoints...but how do they know the cells are "fit" to continue forward to the next phase.

  • @rochelroma180
    @rochelroma180 4 года назад +2

    thank you professor dave

  • @nastehaibrahim3797
    @nastehaibrahim3797 6 лет назад +3

    Thank you so much for this informative video

  • @Bilbus7
    @Bilbus7 6 лет назад +2

    Thank you brother Dave!

  • @shadmehr8341
    @shadmehr8341 Год назад

    Very nice job Prof Dave!

  • @veraojemu5105
    @veraojemu5105 5 лет назад +1

    This was great.
    So simplified!!
    Thanks.

  • @SamaAhmed-ox3ed
    @SamaAhmed-ox3ed Месяц назад

    سبحان الله العظيم ❤
    سبحان الخالق ❤
    سبحان ارحم الراحمين ❤
    سبحان الهادي❤
    سبحان المصور اللطيف ❤

  • @peter.biedermann1756
    @peter.biedermann1756 6 лет назад +1

    Man , that was well expained. Thank you!

  • @ahamadaoukachioukachi7269
    @ahamadaoukachioukachi7269 4 года назад +2

    OMG THIS IS SO HELPFUL 🌺🌺🌺

  • @biadiciero
    @biadiciero 4 года назад

    perfect!!! sugestion: video about mosaicism

  • @epsilonecho1436
    @epsilonecho1436 3 года назад +1

    While cells are just being cells, Prof Dave is being his usual compartmentalized messiah self :)

  • @wassoun7934
    @wassoun7934 5 лет назад +1

    Amazing explanation thank you 🙂

  • @nalwogaphiona225
    @nalwogaphiona225 3 года назад +1

    It's well explained. Thank u

  • @janakmedicos9735
    @janakmedicos9735 4 года назад

    Controlled cellular multiplication. And age related healing and Cancer treatment.

  • @raanimalik4007
    @raanimalik4007 2 года назад

    just here to say man ur saving my butt. I love you

  • @mustaphasuso922
    @mustaphasuso922 2 года назад

    You have been carrying me since high school am am in university thanks

  • @AlexTrusk91
    @AlexTrusk91 4 года назад +2

    0:12 looks like a big strong blue guy with red head. Noone you want to argue with trying to get into a club.

  • @aelliyanti
    @aelliyanti 3 года назад

    Thank you so much for excellent explanation

  • @dahianaortiz6216
    @dahianaortiz6216 9 дней назад

    When does protein synthesis occur (transcription and translation) in relation to cell cycle.
    Mitosis happens all the time for some cell?
    Both meiosis cycles happens how many times in an organism life time? Once?

  • @winsorblue2428
    @winsorblue2428 4 года назад +2

    This is like watching Cr1TiKaL teach me about biology. Thanks!

  • @josefa8939
    @josefa8939 2 года назад

    Your videos are great, thank you! FYI, the word "kinase" is pronounced KAI-nase.

  • @polokocollen7072
    @polokocollen7072 6 лет назад +1

    Thank you ...well explained.

  • @AnzzCheatedOnMarkWithHaechan
    @AnzzCheatedOnMarkWithHaechan 4 года назад +1

    This is so helpful!!
    Thank youu

  • @vasilistoma7082
    @vasilistoma7082 Год назад

    great video really helpful thanks a lot

  • @jenniferwang946
    @jenniferwang946 4 года назад +1

    1:03 Why are they called daughter cells? And not son cells, for example?

    • @AnushkaSharma-ok2er
      @AnushkaSharma-ok2er 3 года назад +2

      we call it daughter cell since only *female* can reproduce.. so as it will grow it will become a mother cell and divide further.

  • @lennymusungu7506
    @lennymusungu7506 Месяц назад

    this is good. Love it

  • @Osama_Alkadomi
    @Osama_Alkadomi 3 года назад

    after studying biology in depth for many years I have slowly but surely started believing in a higher power. And after further research I have decided that there can only be 1 God responsible for the intricacy of the human body.

    • @WokeandProud
      @WokeandProud 3 года назад

      As long as you don't take it too far and become a YEC then that's perfectly fine I disagree strongly because of things like emergence but it's fine of that's what you wanna believe.

    • @Osama_Alkadomi
      @Osama_Alkadomi 3 года назад

      @@WokeandProud I do not understand what you mean by "taking it too far" secondly, things like emergence personally are not strong enough evidence to compensate for the incredible intricacy of the Universe and human physiology. However, I would not impose my beliefs on others. Although, there has to be a set of laws prohibiting homosexuality, illicit acitivities etc.

    • @e.m.5287
      @e.m.5287 Год назад

      ​@@Osama_AlkadomiNo.

  • @abdeljalilpr2033
    @abdeljalilpr2033 7 лет назад +1

    I was asking my self how this signal are translated ??what is this signal??elecrones ??protons?? Need more detail...any way this is a very good channel respect from morocco

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад +3

      i talk about the signaling molecules in this clip! they interact with the genome to promote or inhibit gene expression. stay tuned for a future clip on regulation of gene expression.

    • @thedisintegrador
      @thedisintegrador 7 лет назад

      Usually some proteins or hormones

  • @nu.ri22
    @nu.ri22 Год назад

    Thank you so much sir 🙏

  • @manjulaapm5551
    @manjulaapm5551 5 лет назад

    Thanks . It helped me a lot.

  • @fluxonluck7712
    @fluxonluck7712 4 года назад

    Well done 👍

  • @fredpipsy3692
    @fredpipsy3692 3 года назад

    Thank professor dave

  • @Ihsannurulimansfd
    @Ihsannurulimansfd 4 года назад

    one quick question dave. if nerve cells don't divide at all like you said, then how can doctors treat brain cancer? bcs, once the doctors get rid the tumor cells within the brain, don't they wait for certain amount of times so that the cells he cut form the new one. thanks

  • @hacernurertunc4529
    @hacernurertunc4529 6 лет назад +2

    Even though I don't speak English, I understood the pictures.

  • @Truthfully-Dreamworld
    @Truthfully-Dreamworld 4 дня назад

    I have a test in one hour thanks 😊

  • @lilacrose6828
    @lilacrose6828 2 года назад

    You absolutely excellent.... Lacture

  • @deeblessings8547
    @deeblessings8547 2 года назад

    This is way better than crush-course.

  • @Osama_Alkadomi
    @Osama_Alkadomi 2 года назад

    You gotta be using the campbell biology book

  • @rosev6052
    @rosev6052 2 года назад

    i think there is an error at 1:57

  • @bioarh874
    @bioarh874 5 лет назад

    Can someone explain what the role of the Destruction-Box is ?

  • @katerihiga2087
    @katerihiga2087 5 лет назад

    Very clear thank you

  • @chinopopop
    @chinopopop 7 месяцев назад

    Thank you ❤️

  • @krishnabarge2837
    @krishnabarge2837 5 лет назад

    Understood everything sir..😁

  • @flintey360
    @flintey360 3 года назад

    Thanks King

  • @cindodo3854
    @cindodo3854 6 лет назад

    THANK YOU SO MUCH MAN!

  • @saketkumar4972
    @saketkumar4972 9 месяцев назад +1

    Why don't we just cut that skin part where cell is dividing rapidly?

  • @drnykterstein_
    @drnykterstein_ Месяц назад +1

    I always confuse you with penguinz0

  • @vailethmahenge9180
    @vailethmahenge9180 3 года назад

    Thanks 👍👍

  • @aasemahsan
    @aasemahsan 2 месяца назад

    Cyclin + CDK = MPF (Maturation promoting factor)
    Density dependent inhibition

  • @nyawirawaithaka4993
    @nyawirawaithaka4993 6 лет назад

    Thank you!

  • @lauramejia7103
    @lauramejia7103 6 лет назад +1

    Hey Todd!! aha come on phagocyte! - haha I need to talk to people, I've been studying too long

  • @WhirlwindHeatAndFlash
    @WhirlwindHeatAndFlash 2 года назад

    reminder to self:
    6:46

  • @sturgeondtd9522
    @sturgeondtd9522 4 года назад +1

    Lmao Kin-aces got me, it is usually pronounced kyn-ace

    • @angeliquatata
      @angeliquatata 9 месяцев назад

      Okayyyy?? You want a cookie??

  • @simplicitas5113
    @simplicitas5113 4 года назад

    How is this guy a professor. He is what, 32?
    EDIT: Also way too good teacher for a professor, especially in Cellbiology.
    Psst spoiler, he is just a Bachelor.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 года назад +1

      I'm 37, it's a RUclips channel, and I'm a science communicator with a BA and MS.

  • @lighttecdark3504
    @lighttecdark3504 9 месяцев назад

    Dude you are awesome! :D

  • @carolinelhouvum2251
    @carolinelhouvum2251 4 года назад

    Thank you thank you

  • @joshtickner3339
    @joshtickner3339 Год назад

    Do cells grow during the g0 phase?

    • @hawialmaw7367
      @hawialmaw7367 2 месяца назад

      Nope, G0 phase simply means undividing phase or a phase where cells are at rest

  • @Unicornbeauty1234
    @Unicornbeauty1234 5 месяцев назад

    Thank u bro

  • @pastimepursuit7212
    @pastimepursuit7212 3 года назад

    1:57 it's actually "We, humans, ..." sorry not sorry lol

  • @StudyHoursV2
    @StudyHoursV2 3 месяца назад

    Watched understanding 3/5- all dna in a chromsome is copied, wrote down notes in my bio textbook, so I will refer back to that when studying (im a bit lazy to copy down everything i learnt)

  • @ilhamhasan8950
    @ilhamhasan8950 7 лет назад +1

    شكرا

  • @henrytai4030
    @henrytai4030 6 лет назад +1

    hi taylor

  • @SrTBP
    @SrTBP 6 лет назад

    Wow! This is great continent! Simple and accurate! Just consider revising your explanation on chromatin structure...As far as I know chromosomes only go supercoiled for cell division...the DNA is largely in a "loose" state for replication and storage... otherwise it couldn't be used. (I'm not considering heterochromatin here, of course)
    Anyhow, great video!! :)