The Cell Cycle and its Regulation
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- Опубликовано: 2 июл 2024
- Your cells have to divide when you're growing, to heal wounds, and to replace dead cells. But how do cells know when to divide and when not to divide? We can't have cells just growing willy-nilly! That's what cancer is, and that's bad. Luckily, cells obey something called the cell cycle, which is regulated by a variety of signaling molecules, which tell the cell when to divide and when to chill out. Let's look at the phases of this cycle and some of its regulatory mechanisms now.
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I am a tutor in physiology, physics, chemistry, and mathematics, and I must say you have a very special way of breaking down the information in a comprehensible, sequential manner that is just really enjoyable to hear and watch. You are definitely helping a lot of people with your linear, step-by-step methods. I've always been fond of cell signaling pathways and understanding them from start to finish. Very well organized!
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Jared Nicholas Really. what physiology do you teach? cell biology?
I agree. easy to understand. Good job Professor Dave. I'm also a Science Teacher.
@@ProfessorDaveExplainswhich type of cells? Just asking am not medical profession. Is it stem cells or lymphocytes?
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THANK YOOOOOOU. I looked everywhere for a decent video that explains this stuff! This video is clean and not a jumbled and crazy. PLEASE DONT STOP MAKING VIDEOS THEY'RE TOO GOOD!
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I've been struggling in class to understand the checkpoints and have had no luck in finding videos that explain how it works. I greatly appreciate your help and finally have a sense as to what is going on!
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This helped a little on the subject, thanks. I even learned some extra information!
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This was great.
So simplified!!
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this is great video! really helped me understanding cell cycle regulation! thanks!
I LOVE THIS TYPE OF CONTENT. THANK YOU. HIGH SCHOOL ALL OVER AGAIN BUT THIS TIME I'M FOCUSED AND INTERESTED.
its reassuring to see that the numbers in my textbook line up perfectly with the examples you give. you are quite literally on the same page.
I am astonished by how you explained it so well. Well done...
Farhan Ahmed yes i wish if it was in arabic bt this is good too
Thank you so much for this informative video
Man , that was well expained. Thank you!
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Thank you ...well explained.
It's well explained. Thank u
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Well explained, understandable and clear... Thank you prof. All your videos are very useful. I've been watching all of them.
This is so helpful!!
Thank youu
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Please make videos with more explanation ....request. Your videos are best .
İ wish to have you in my collage dude, i didn't just learn, i enjoyed it
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Quick question-
Chromosomes can be monads (a single chromatid) or dyads (sister chromatids held together by a centromere; a dyad has two identical strands of DNA held closely together in a location called the centromere). When a cell is in the G1 or Gap 1 Phase of their cell cycle, the nucleus contains monads but during the S phase the DNA is synthesized into the dyads that are seen in the G2 or Gap 2 phase.
*The strands are identical assuming that no copying errors (mutations) have occurred during the S phase of the cell cycle
Familiarize yourself with the conditions of a cell’s chromosomes during the G1 and G2 phases of the cell cycle.
The 4 phases of mitosis:
Prophase = chromosomes condense
Metaphase = chromosomes line up in the middle of the cell with reference to the two poles (the equatorial plate or metaphase plate) with each chromosome on its own spindle fiber (by itself)
Anaphase = separation of the chromosomes
Telophase = formation of two nuclear envelopes around the two chromosomal clusters and then the cell divides (cytokinesis)
Questions:
In humans, there are 46 chromosomes in the nucleus of a cell. When the cells are in the G1 phase the 46 chromosomes are 46 monads which are 46 single chromatids. During the S Phase the 46 monads become 46 dyads which are 46 sister chromatids that will split during the M Phase/Mitosis. What is in the nucleus of the cell after mitosis?
great video really helpful thanks a lot
OMG THIS IS SO HELPFUL 🌺🌺🌺
Well done 👍
Very clear thank you
Man I gotta love that iconic intro
In school, we watch the explanation videos. At home, I watch the debate videos.
perfect!!! sugestion: video about mosaicism
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Thank professor dave
Thank you!
@dave So Cyclins and kinases provide the signal to help the cell move along through the checkpoints...but how do they know the cells are "fit" to continue forward to the next phase.
At this point its not my degree, its our degree!
thanks for the content as always!!
You absolutely excellent.... Lacture
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You deserve way more subscribers
i agree! please tell your friends :)
Thanks King
Your videos are great, thank you! FYI, the word "kinase" is pronounced KAI-nase.
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Understood everything sir..😁
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one quick question dave. if nerve cells don't divide at all like you said, then how can doctors treat brain cancer? bcs, once the doctors get rid the tumor cells within the brain, don't they wait for certain amount of times so that the cells he cut form the new one. thanks
Controlled cellular multiplication. And age related healing and Cancer treatment.
Dude you are awesome! :D
The Best ever
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Can someone explain what the role of the Destruction-Box is ?
شكرا
While cells are just being cells, Prof Dave is being his usual compartmentalized messiah self :)
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I was asking my self how this signal are translated ??what is this signal??elecrones ??protons?? Need more detail...any way this is a very good channel respect from morocco
i talk about the signaling molecules in this clip! they interact with the genome to promote or inhibit gene expression. stay tuned for a future clip on regulation of gene expression.
Usually some proteins or hormones
0:12 looks like a big strong blue guy with red head. Noone you want to argue with trying to get into a club.
You gotta be using the campbell biology book
This is way better than crush-course.
5:00, 5:20, 5:52, 6:40!, 6:50!, 7:22!, 7:40!, 8:35, 9:44, 10:25, 10:51!, 11:08!
Even though I don't speak English, I understood the pictures.
Do cells grow during the g0 phase?
Todd pls!
hi taylor
hey hey joseph
Wow! This is great continent! Simple and accurate! Just consider revising your explanation on chromatin structure...As far as I know chromosomes only go supercoiled for cell division...the DNA is largely in a "loose" state for replication and storage... otherwise it couldn't be used. (I'm not considering heterochromatin here, of course)
Anyhow, great video!! :)
i think there is an error at 1:57
Hey Todd!! aha come on phagocyte! - haha I need to talk to people, I've been studying too long
1:03 Why are they called daughter cells? And not son cells, for example?
we call it daughter cell since only *female* can reproduce.. so as it will grow it will become a mother cell and divide further.
i love science
I just like the into
😍😍😍✨ Thanks
Why don't we just cut that skin part where cell is dividing rapidly?
How is this guy a professor. He is what, 32?
EDIT: Also way too good teacher for a professor, especially in Cellbiology.
Psst spoiler, he is just a Bachelor.
I'm 37, it's a RUclips channel, and I'm a science communicator with a BA and MS.
"Hey, Todd!"
Why nerve cells never divide?
something about chemical signaling, they must remain in the G0 state!
Professor Dave are you a good or a bad person?
I'm far from perfect, but I'd like to think I skew significantly towards good.
after studying biology in depth for many years I have slowly but surely started believing in a higher power. And after further research I have decided that there can only be 1 God responsible for the intricacy of the human body.
As long as you don't take it too far and become a YEC then that's perfectly fine I disagree strongly because of things like emergence but it's fine of that's what you wanna believe.
@@WokeandProud I do not understand what you mean by "taking it too far" secondly, things like emergence personally are not strong enough evidence to compensate for the incredible intricacy of the Universe and human physiology. However, I would not impose my beliefs on others. Although, there has to be a set of laws prohibiting homosexuality, illicit acitivities etc.
@@Osama_AlkadomiNo.