G Protein Coupled Receptors | Nervous system physiology | NCLEX-RN | Khan Academy

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  • Опубликовано: 3 май 2014
  • Learn about how g protein coupled receptors work in the cell membrane. Created by William Tsai.
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Комментарии • 363

  • @ttaylorfaithh
    @ttaylorfaithh 8 лет назад +676

    why did the video zoom in so much i can't see~~!!

  • @msauthor4989
    @msauthor4989 3 года назад +228

    This guy taught me better in 12 minutes than my professor did in a 45 min class. Kudos dude.

    • @naveedkhankakar144
      @naveedkhankakar144 3 года назад +6

      and my one took more than an hour.

    • @sadah22
      @sadah22 3 года назад +4

      @@naveedkhankakar144 and mine took more than five hours 😫.

    • @fizazainab1526
      @fizazainab1526 3 года назад +3

      Hahahhaha we are in same category

    • @naveedkhankakar144
      @naveedkhankakar144 3 года назад +3

      @@fizazainab1526 hahahaha yup we are.

    • @fizazainab1526
      @fizazainab1526 3 года назад +2

      @@naveedkhankakar144 good luck for your future

  • @Mrjmaxted0291
    @Mrjmaxted0291 5 лет назад +167

    Besides the VERY MINOR flaw in remaining zoomed in during a certain segment this was a very succinct and well presented lesson on GPCRs. Thanks for posting it up, it's been a great overview to revising the key concepts.

  • @asmahaque8558
    @asmahaque8558 5 лет назад +189

    I HAVE SPENT 2 YEARS IN MED SCHOOL MANEUVERING MY WAY THROUGH COUJTLESS EXAMS AND VIVAS WITHOUT EVER REALLY UNDERSTANDING THIS! UNTIL TODAY! THANK YOU

    • @ozymandias5449
      @ozymandias5449 3 года назад +7

      this is me right now haha

    • @Urtoomuchjosh
      @Urtoomuchjosh 3 года назад +25

      thats kinda sad

    • @chenchoon8751
      @chenchoon8751 2 года назад +2

      Did you graduate yet? If so, congratz!

    • @godferymbadiwe4754
      @godferymbadiwe4754 Год назад

      How far
      I need a mentor. I just got into my first year of medical school

  • @DollyDomDom
    @DollyDomDom 3 года назад +61

    This was perfect! The only thing this video missed was that after ATP is converted to CAMP, CAMP then goes on to activate Protein Kinase A to THEN produce the physiological effects.

    • @gmmg834
      @gmmg834 Год назад +2

      Thank you for your contribution

    • @juliana-qf
      @juliana-qf Год назад +1

      to talk about this would be a specific video about the second messengers

  • @danjbundrick
    @danjbundrick 8 лет назад +133

    Except for the zooming error, this video was a spot on. Thank you. I heard that it was called "adenylyl cyclase" though.

    • @danjbundrick
      @danjbundrick 8 лет назад +2

      +Jai A Meyrick Thanks. I'll have to remember that.

    • @danielortega494
      @danielortega494 7 лет назад

      Daniel Bundrick g

    • @Vikramt08
      @Vikramt08 5 лет назад

      Adenylate cyclase

    • @jayrabah8064
      @jayrabah8064 4 года назад +2

      It does the same thing ,but it’s an amplifier enzyme so I think there must be a difference

    • @hobobazaar8196
      @hobobazaar8196 2 года назад +2

      Adenylate cyclase, adenyl cyclase, & adenylyl cyclase are all the same enzyme. Confusing redundant names, that's science.

  • @nels6991
    @nels6991 7 лет назад +162

    Great video! FYI the zoom only lasts for like 30 seconds yall ;)

    • @a.stuckmann431
      @a.stuckmann431 3 года назад +3

      more like 1 -minute......

    • @jonahansen
      @jonahansen 3 года назад +1

      It goes from 4:03 to 5:23 for a total of 1:20 or 1 minute and 20 seconds, plus or minus a few seconds.

    • @materialgowrl1553
      @materialgowrl1553 3 месяца назад

      well with subject like this, every second is crucial, the dude fucked me up

  • @jjocelynjustice
    @jjocelynjustice 9 лет назад +42

    This video helped the concept of G proteins finally click in my brain. Thank you!

    • @santheeshsantheesh5746
      @santheeshsantheesh5746 4 года назад

      Jocelyn Justice go for The Great Dr.Najeeb if you really want to build your concept

  • @cmgkk
    @cmgkk 10 лет назад +6

    Great clear explanation. I studied this back in undergrad and want to carry out an experiment now in my PhD where I inhibit G-alphaS and see downstream function. I need a quick re-fresher and this hit the spot! Thanks!

  • @joeanderson7841
    @joeanderson7841 8 лет назад +41

    Thank you sir, it helps me a lot for my final exam

  • @stephyunion
    @stephyunion 7 лет назад +18

    I like the way you explain this 5-full-pages theory in a simple way. Thank you! This helps me for my tomorrow exam ehehehe

  • @alisthompson
    @alisthompson 7 лет назад +234

    Please fix the zooming issue!

    • @oxysmoxy1977
      @oxysmoxy1977 7 лет назад +1

      You have to change it to full screen, it worked for me :)

    • @sherhorse
      @sherhorse 4 года назад +9

      @@oxysmoxy1977 doesn't work

  • @user-kh7gx4rc6c
    @user-kh7gx4rc6c 9 лет назад +8

    Brilliant. Really helpful.! Thanks a lot

  • @tiruvgiri1519
    @tiruvgiri1519 5 лет назад +6

    How hours of boring lectures are made into a 12 min riveting knowledge is always going to be a mystery to me #Khanacademy.
    Thank You for saving my life btw

  • @rocketbabydoll93
    @rocketbabydoll93 9 лет назад +2

    This video is my lifesaver. Thank you so much!

  • @jess100ize
    @jess100ize 5 лет назад +6

    What would I do without Khanacademy?? Great explanation, as always😁👌🏼

  • @user-mw5wq1zl9w
    @user-mw5wq1zl9w 5 лет назад +1

    EXACTLY what i was looking for!! thank you!!

  • @nonewthing2883
    @nonewthing2883 2 года назад +3

    This guy taught me better in 12 minutes than my lecturer did in a 2 hour class. Levels, thanks dude.

  • @FarheenFathima397
    @FarheenFathima397 3 года назад +2

    Greatest video ever. loved it. Thank you for being alive.

  • @chenlynn951
    @chenlynn951 9 лет назад

    WONDERFUL!!! I learned more from this video than my 3-hour-long graduate class!!! THANK YOU VERY MUCH!!!

  • @drdivishaverma6242
    @drdivishaverma6242 7 лет назад +7

    too good! 👍🏻

  • @AK-ut3id
    @AK-ut3id 9 лет назад +3

    Thank you. Absolutely amazing! :)

  • @dilaozut
    @dilaozut 4 года назад +1

    Your speech was so clean that despite my poor english i could have understood you well. thank you :)

  • @Wessam12345678910
    @Wessam12345678910 8 лет назад +1

    Perfect explanation... thank you alot!

  • @nampotiwong9863
    @nampotiwong9863 2 года назад +1

    This video saves my 1st year as a medical student!!!!! Thank you so much!!!!!

  • @dexkani9993
    @dexkani9993 3 месяца назад +3

    Bruh, it's been 9 years, this video needs a re-edit for those precious minutes gone while it was zoomed in

  • @DuyNguyen-qv3pi
    @DuyNguyen-qv3pi Год назад +1

    Thank you so much. I went through my lecture slides, recording but still not understanding a piece of information like you did in 12 minutes. I am so grateful to be here with other students.

    • @exemplarypersonality6562
      @exemplarypersonality6562 4 месяца назад

      Same here, the lecture and audio from my boring lecturer was always inducing sleep

  • @rachelst1046
    @rachelst1046 7 лет назад +1

    That was excellent - thank you so much for a wonderful education explanation :)

  • @princemulenga1621
    @princemulenga1621 2 года назад

    Amazing explanation, simple and straight to the point. thank you!!!

  • @paulgrosenstein5202
    @paulgrosenstein5202 5 лет назад

    Excellent video! Thank you for the thorough explanation.

  • @mariapiadellomo2213
    @mariapiadellomo2213 8 лет назад +2

    Well explained! Greetings .

  • @ODjigo
    @ODjigo 9 лет назад +1

    such a bless ! thanks bro ! helped me alot !

  • @adlinanatashaamirudin8999
    @adlinanatashaamirudin8999 8 лет назад

    It helps me a lot!! lots of thanks.. it's very clear and simple.

  • @jasneetpabila
    @jasneetpabila 8 лет назад

    This was really helpful! Thanks so much :)

  • @dahneershanair5809
    @dahneershanair5809 8 лет назад

    This helped me a whole lot. Thank you. :)

  • @johnmulemwa6609
    @johnmulemwa6609 9 лет назад +11

    Wish harper's was easily understood as this........

  • @xrelaxbear
    @xrelaxbear 6 лет назад

    thank you so much, i learned more from this video than i did in a 2 hour college lecture..

  • @davidrosen5137
    @davidrosen5137 6 лет назад

    Extremely helpful. Thank you!

  • @andreeadavidean2787
    @andreeadavidean2787 Год назад

    Thank you, i finally understood this!

  • @nadineosama8726
    @nadineosama8726 9 лет назад +1

    You are a lifesaver God bless you 😍

  • @sarabe2930
    @sarabe2930 8 лет назад

    i couldnt get the topic on my lecture but now it is all clear! thanks a lot! Thumbs up :)

  • @margaretmora1081
    @margaretmora1081 3 года назад

    Wonderful and clear! Thank you!

  • @anastassiyageorgiev6661
    @anastassiyageorgiev6661 10 лет назад

    awesome explanation! thank you!!

  • @ch-p2861
    @ch-p2861 7 лет назад

    Great video! Thanks so much!

  • @learnteach2learn729
    @learnteach2learn729 5 лет назад +1

    tHIS MAKES SO MUCH SENSE

  • @maryamsed6023
    @maryamsed6023 5 лет назад +1

    Woow thank u so much, u explained such a hard tissue sooo easily and clearrrr, ur greattt

  • @lizj8921
    @lizj8921 5 лет назад

    Made this sooo much easier to understand!

  • @wahidwithanapron1467
    @wahidwithanapron1467 5 лет назад

    It was an excellent video!!!! Explained so accurately 😊

  • @katefuglestad5894
    @katefuglestad5894 Год назад

    Very helpful! Thank you. The visual really helped.

  • @eliawilckriph1269
    @eliawilckriph1269 11 месяцев назад

    for the first time iunderstand the concept of GPCRs. Thank you

  • @Hiphop101ize
    @Hiphop101ize 6 лет назад +1

    I get that the alpha subunit of the g protein acts s a regulaator after it's activted. But wht do the bet and gmma subunits do? Is their only functtion to block the alpha subunit from being activated all the time?

  • @HashemSmashem
    @HashemSmashem 7 лет назад +13

    Lol did a cat jump on your notes @7:45? 😂 Awesome, clear, accurate, and well explained video btw. The zooming-in issue wasn't very hindering in terms of understanding the concept, but it would be that much better if it was fixed. 9/10

  • @brade469
    @brade469 9 лет назад +1

    Great video; liked it. But question, can you call the beta & gamma subunits a dimer if they are not identical molecules?

  • @colindaines3552
    @colindaines3552 3 года назад

    Super helpful video!

  • @arjungole9387
    @arjungole9387 8 лет назад

    thank you...perfect explaination!!

  • @jonxthxn1
    @jonxthxn1 Год назад

    Thank you so much for this!

  • @soumyanag2328
    @soumyanag2328 5 лет назад

    You have just activated my G-Protein awsm Khan Academy Simple Smart and Conceptual what else do we need

  • @rubyyxlc3936
    @rubyyxlc3936 6 лет назад +17

    5:23 continued from zoom out

  • @jadattia6723
    @jadattia6723 6 лет назад +2

    great job . thanks from Syria

  • @lissseveneleven
    @lissseveneleven 8 лет назад +1

    thank you so much!

  • @thanatosiax
    @thanatosiax Год назад +1

    MY PROFESSORS COULD NEVERRR. THANK YOUU 🥹🫶🏼

  • @kashfsheikh4840
    @kashfsheikh4840 5 лет назад

    Thaaank Youuu!!! It was so beautifully explained. I love you for this!!!

  • @ahmetziyaaktas9179
    @ahmetziyaaktas9179 2 года назад

    So nice and clear explanation was it that I liked so much. I really appreciated it!

  • @payasitarosita
    @payasitarosita 10 лет назад

    Very clear, thank you!

  • @jinx3332
    @jinx3332 3 года назад

    Thank you!!! Helpful

  • @chickengirlslyrics
    @chickengirlslyrics 2 года назад

    This video made so much sense. Thank you so much!!!!

  • @rezarezanaghibi
    @rezarezanaghibi 3 года назад

    It was just great! Thanks for sharing :)

  • @juleschannel3934
    @juleschannel3934 5 лет назад

    Well done, great video!

  • @Eli_1412
    @Eli_1412 3 года назад

    Thank you very much! You explained it really well:)

  • @hinashaukat246
    @hinashaukat246 4 года назад

    Finally got the concept of g protein ,thanku for this work 👍

  • @dr.zaina.0
    @dr.zaina.0 Год назад

    Thank you very much that’s help me more 🙌❤

  • @AJ-rd6ez
    @AJ-rd6ez 3 года назад

    Wow this is SO helpful!!!!! Thank you

  • @amreshrandive5371
    @amreshrandive5371 9 лет назад

    Very Helpful explanation. Thank you.

  • @addy4348
    @addy4348 8 лет назад

    just perfect!! thanx a lot

  • @ashokchhatkuli8767
    @ashokchhatkuli8767 7 лет назад

    thanks very much, it helps a lot!

  • @user-vq2oe9cs7z
    @user-vq2oe9cs7z 4 года назад

    So helpful 😍 thank you so much for perfect explanation 👍🏻

  • @lelouchlamperouge2085
    @lelouchlamperouge2085 8 лет назад +1

    nice n clear explanation :)

  • @unconventional100
    @unconventional100 9 лет назад

    Many thanks.
    Concise and beneficial.

  • @christopherh.7008
    @christopherh.7008 9 лет назад

    Great Video! Thank You

  • @ruksanakhan4989
    @ruksanakhan4989 3 года назад

    Informative video... thnx a lot

  • @juanherrera7282
    @juanherrera7282 4 года назад

    Excellent , thank you

  • @timjuarez1178
    @timjuarez1178 5 лет назад

    thank you for clearly explaining things.

  • @niteshsah7259
    @niteshsah7259 4 года назад

    such a good video and explanation on GPCR. Great 👌👌

  • @user-ue2tb8tn9b
    @user-ue2tb8tn9b 4 года назад

    Thank you! Good video

  • @anilocm5457
    @anilocm5457 3 года назад +1

    This is a savior 👏

  • @taiganakazawa1390
    @taiganakazawa1390 9 лет назад

    very good video, thank you very much!

  • @srkzn5304
    @srkzn5304 6 лет назад

    You are awesome! thank you so much!!

  • @cm-in4il
    @cm-in4il 3 года назад

    this was so helpful! i do understand the entire process now, even though my mother langue is German (: thank you

  • @luisrm37
    @luisrm37 4 года назад

    Wow that was great!

  • @danahmed2659
    @danahmed2659 Год назад

    Thank you so much!!!

  • @leerunkang8237
    @leerunkang8237 Год назад

    Thank you for the simplest , you explain better than my professors at the collage and for free

  • @arunabhSiddhartha
    @arunabhSiddhartha 7 лет назад

    Very well explained!

  • @SuperAlbalawi
    @SuperAlbalawi 6 лет назад

    I really thank you sir for this great video, tomorrow I’m taking a physiology exam

  • @bwiremartin805
    @bwiremartin805 Год назад +1

    please help me with the kind of textbook
    that you guys use
    its really very well understood

  • @jarromflightfeather
    @jarromflightfeather 5 лет назад +1

    Does the GTP replace the GDP? Or does a phosphate bind to the already-bound GDP creating GTP on the alpha subunit?

  • @adenmadi
    @adenmadi 2 года назад

    Thnx for the explaination 👍

  • @angebannisteroffical
    @angebannisteroffical 8 лет назад

    Thanks a ton!

  • @Adhikash015
    @Adhikash015 7 лет назад

    Thank you soo much for this video man....

  • @KMedina514
    @KMedina514 7 лет назад

    great explanation!

  • @anaherrera4805
    @anaherrera4805 Год назад

    Excellent explanation!! Thank you