Inositol Triphosphate (IP3) and Calcium Signaling Pathway | Second Messenger System

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  • Опубликовано: 14 ноя 2024

Комментарии • 93

  • @danielareyes9920
    @danielareyes9920 5 лет назад +96

    Thanks so much for this!! I sat through a 2 hr lecture and didnt understand but I got it here after less than 6 mins lol. You’re a lifesaver

  • @josephandhopelopez8492
    @josephandhopelopez8492 4 месяца назад +2

    Who created this magnificent, elegant, yet simple mechanism? The way PIP2 is disassembled into two useful parts is genius! Calcium is stored and is only released with the key (IP3), genius! This is a very controlled chemical pathway needing several keys (DAg, IP3, and Calcium. It must be responsible for very intricate balances in the cell. Thank you for making this elegant pathway simple to understand and accessible to marvel at. Thank you!

    • @ДарияМинеева
      @ДарияМинеева 4 месяца назад

      nature did 🏞. Sometimes I wonder how a human could kill another one, if they are both such attuned systems where every molecule or ion counts 😣

  • @jacksilver2884
    @jacksilver2884 2 года назад +13

    Unbelievably useful explanation, so well laid out. Thanks

  • @CT--gs1wj
    @CT--gs1wj 5 лет назад +42

    you should have included the activation of G alpha subunit by GPCR which then activates phospholipase C... regardless, the video is excellent.

  • @royaldiini
    @royaldiini Месяц назад

    Wow, that was amazing. Thank you so much for explaining this in a such a calm voice and easy to understand so much appreciated.

  • @keurinrin16
    @keurinrin16 3 года назад +4

    Read my book for a week and I had a hard time understanding this topic. And I just discovered this video and now I understand hahah thankyou very much!Please make more videos like these

  • @pureispure3184
    @pureispure3184 5 лет назад +11

    Saved my brain cells, thx

  • @MustafaAhmed-eh1kk
    @MustafaAhmed-eh1kk Год назад

    Thank you so much!
    It's very simple & clear.

  • @Esraa-mr9ce
    @Esraa-mr9ce 4 года назад +1

    Wow!! It is clear explaination to a complex pathway ...please keep on

  • @Veronica-nx3ss
    @Veronica-nx3ss 4 года назад +1

    I think I may have a metabolic disorder, and my doctor keeps telling my symptoms are psychosomatic, I am trying to do some personal research about non epileptic childhood seizures and how that effected my metabolism. I appreciate the video in helping me better understand the concepts in the papers I am reading.

  • @buho3539
    @buho3539 6 лет назад +5

    Thank you. You have great videos. Greetings from Colombia

  • @Student-jb8pe
    @Student-jb8pe 5 лет назад +1

    Your channel is so underrated!

  • @nyawirawaithaka4993
    @nyawirawaithaka4993 5 лет назад +1

    WoW! Best explanation I have found on this topic. Thank you!

  • @andreasalazar4126
    @andreasalazar4126 3 года назад +1

    YOU ARE AMAZING. THIS WAS SO EASY TO UNDERSTAND! ALL CAPS CUZ YOU ROCKED IT

  • @sometimes418
    @sometimes418 2 года назад

    The best video on this topic !

  • @emran9699
    @emran9699 2 года назад

    OMG this was so a smooth explanation
    Thanks alot

  • @HameedahHamza
    @HameedahHamza 7 месяцев назад

    Thank you so much, I watched like 5 different videos on this topic but still didn't get it but I do now

  • @Ivy-nw7ny
    @Ivy-nw7ny 4 месяца назад

    Thank u, it's really helpful❤️

  • @sruthik-jn9rd
    @sruthik-jn9rd 12 дней назад

    Thankyou so much for this video 😇

  • @diffimalonekavunga6549
    @diffimalonekavunga6549 3 года назад

    Thank you for this ! A life saver!

  • @sihlemnisi1310
    @sihlemnisi1310 5 лет назад +2

    Thank you. This was extremely helpful.

  • @misstulip1164
    @misstulip1164 3 года назад

    I fall in love with this video. 😂😂😂.No I am kidding but it’s really helpful thank u so much 💜💜💜💜💜

  • @esraa5179
    @esraa5179 2 года назад

    simple and clear! thank you so much

  • @peggy1998qiqi
    @peggy1998qiqi 5 лет назад +1

    thank you so much! Easy and simple explanation.

  • @akshayapanneer1746
    @akshayapanneer1746 3 года назад

    Amazing xplaination.....i loved it so much 💖

  • @daniahalkhatib8058
    @daniahalkhatib8058 2 года назад

    Thankk youuu♥️ god bless you 🙏🏽

  • @biancalmg
    @biancalmg 8 месяцев назад

    Great video, thank you!

  • @premalmartin3246
    @premalmartin3246 5 месяцев назад

    Thank you, my physiology book did a terrible explanation along with a figure that didn't seem to go along with the explanation.

  • @ivypellerin1000
    @ivypellerin1000 3 года назад +1

    thank you thank you

  • @marishenmarindi6046
    @marishenmarindi6046 Год назад

    2023 this was really helpful

  • @chidalumichelle3009
    @chidalumichelle3009 8 месяцев назад

    Thank you so much for this

  • @lmelimelo031
    @lmelimelo031 5 лет назад

    Wow I've just discovered your channel, and it's really good ! Really simple explanation for so big pathway, you save me for an oral I have. Thanks !

  • @rohitrchavan1543
    @rohitrchavan1543 4 года назад

    Saved my day!! Thank you

  • @cardiacmyxoma4073
    @cardiacmyxoma4073 3 года назад

    This is perfect, thank you!!!

  • @ayezageza563
    @ayezageza563 5 лет назад +2

    legend ...thank you so much

  • @QuacK_001
    @QuacK_001 4 года назад

    Very good video, thank you so much.

  • @lionsinescanor373
    @lionsinescanor373 2 года назад

    great simplification!

  • @Lovefornature555
    @Lovefornature555 3 года назад +1

    Beautiful

  • @ينتيايينثنوبتب
    @ينتيايينثنوبتب 3 года назад +1

    Thanks

  • @krokodilledertasche8412
    @krokodilledertasche8412 5 лет назад

    A wonderful work! Well done and Thank you👍👌

  • @haojianli9626
    @haojianli9626 2 года назад

    Very helpful!

  • @NourBrahimi-fv8ek
    @NourBrahimi-fv8ek 10 месяцев назад

    Thank you so much ❤

  • @tiptrick7762
    @tiptrick7762 3 года назад

    Tro cool z'espere zaurait 20 sur 20 grasse à toi

  • @Kats.Aquatics
    @Kats.Aquatics 11 месяцев назад

    Amazing thank you

  • @MashaimNoor-b2u
    @MashaimNoor-b2u 6 месяцев назад

    Very informative

  • @starsdv2643
    @starsdv2643 4 дня назад

    Thank u so much

  • @sanalsimon7657
    @sanalsimon7657 5 лет назад

    Thanks a lot!! it helped so much.

  • @Ash-bl9ye
    @Ash-bl9ye 6 месяцев назад

    Great video

  • @arif-tx1hm
    @arif-tx1hm 2 года назад

    understood, thankyou🙂

  • @mwenimumba7227
    @mwenimumba7227 3 года назад

    Awesome!!!

  • @MaitiaVangLover
    @MaitiaVangLover 5 лет назад

    Thank you for this!! I appreciate it!

  • @Fienaz1010
    @Fienaz1010 3 года назад

    THANK YOU SO MUCH!

  • @mhmdfalahati5063
    @mhmdfalahati5063 Месяц назад

    Amazing

  • @blackpearl3349
    @blackpearl3349 4 года назад +1

    You have to rename this video how to save your life in less than 6 min ❤️thx ❤️❤️

    • @jjmedicine
      @jjmedicine  4 года назад

      Haha - glad it helped :)

  • @hklena6274
    @hklena6274 5 лет назад +1

    Great video, just a quick question. Is it not the sarcoplasmic reticulum (rather than endoplasmic) that calcium is released from into the cytosol?

    • @exiar359
      @exiar359 5 лет назад +2

      The sacroplasmic reticulum exists only in muscle cells but I believe the video is talking about a typical body cell.

  • @Nabaa-l2g
    @Nabaa-l2g 4 года назад

    Thank you so much that was really helpful 😻

    • @jjmedicine
      @jjmedicine  4 года назад

      You're so welcome! Glad you liked it :)

  • @Luffy-wv1kh
    @Luffy-wv1kh 7 месяцев назад

    excellent

  • @salamabbb
    @salamabbb 11 месяцев назад

    Perfect

  • @kawther6351
    @kawther6351 4 года назад

    It is amazing thanks

  • @mahdiomidvar564
    @mahdiomidvar564 3 года назад

    exactly .... you are a lifesaver

  • @loubnadr7407
    @loubnadr7407 2 года назад

    thank you

  • @طنطلطيفة
    @طنطلطيفة 3 года назад +1

    💖💖💖💖

  • @welkingunther4298
    @welkingunther4298 5 лет назад

    Beautiful.

  • @Rico7817
    @Rico7817 5 лет назад

    ty!! great video!

  • @hybridhelix88
    @hybridhelix88 5 лет назад

    Sinply the best !

  • @setsunee
    @setsunee 4 года назад

    Hello I have a question, what would cause this pathway to be terminated or stopped? Thank you.

  • @sobialaghari225
    @sobialaghari225 5 лет назад +1

    But why is PIP2 no second messenger? It does it work too right?

  • @anaskrazem444
    @anaskrazem444 6 лет назад

    Thank you ☺

  • @kashifalikhan5124
    @kashifalikhan5124 6 лет назад +1

    nice video

  • @sarasims2207
    @sarasims2207 4 года назад

    include the calmodulin and myosin light chain kinase

  • @sandradee9511
    @sandradee9511 4 года назад

    thank youuuuuuu

  • @qaws1103
    @qaws1103 5 лет назад

    Thanks a lot man

  • @detectivepuppycat
    @detectivepuppycat 5 лет назад

    Thank you!

  • @nurfatihahmohdshariff6136
    @nurfatihahmohdshariff6136 5 лет назад +1

    👍🏻👍🏻👍🏻

  • @giomaraustria2371
    @giomaraustria2371 6 лет назад

    What is the specific ligand

  • @esthersim1974
    @esthersim1974 4 года назад

    U da bomb

  • @alima9353
    @alima9353 4 года назад +1

    i think i love u

  • @MsoshjShsnms
    @MsoshjShsnms 2 месяца назад

    Moore Lisa Rodriguez Shirley Walker Helen

  • @daedra40
    @daedra40 4 года назад

    DAG MAG TAG

  • @brigienmartin1485
    @brigienmartin1485 4 года назад

    Hey whatz up

  • @ghassanauf8103
    @ghassanauf8103 4 года назад

    DDDDaag

  • @prathyakshhk9202
    @prathyakshhk9202 2 месяца назад

    2024. viewr

  • @songohan393
    @songohan393 9 месяцев назад

    Thank you

  • @nesmajawahar7926
    @nesmajawahar7926 Год назад

    Can u tell hw its getting degraded ?