The NO-cGMP pathway

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  • Опубликовано: 9 янв 2019
  • This video describes the detailed mechanisms of action of Nitric oxide as a signalling molecule and how it produces cGMP and thereby leads to activation of protein kinase G

Комментарии • 67

  • @saumyaranjansatrusal764
    @saumyaranjansatrusal764 3 года назад +8

    Very nicely explained..with adding the real structures of the molecules.

  • @nola5225
    @nola5225 3 месяца назад +2

    Great video! Very useful! Thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 месяца назад

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @diepnguyen-xg7yn
    @diepnguyen-xg7yn 2 года назад +1

    Very nice explanation, Sir!!! Thanks so much!

  • @horimiya7290
    @horimiya7290 2 месяца назад +1

    Wonderfully explained and succinct!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 месяца назад

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @GAMER20Aayush
    @GAMER20Aayush 3 года назад +12

    I CANT THANK YOU ENOUGH
    THIS ACTUALLY SAVED MY YEAR
    THANK YOU SO MUCH

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад +1

      Please thank me by sharing my channel link with your friends. It would help me to reach big audience

  • @rathodrohan1263
    @rathodrohan1263 Год назад +2

    Best video at all ,that I looking for, greeting..

  • @Wkwkwl7838
    @Wkwkwl7838 24 дня назад +1

    Nicely explained thank you so so so much

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  24 дня назад

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @humanbeing3177
    @humanbeing3177 3 года назад +2

    It is superb. Thanks a lot

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @SuperYaniv12
    @SuperYaniv12 3 года назад +1

    Thank you so so much!

  • @immadisarojini2775
    @immadisarojini2775 4 года назад

    Your videos are wonderful

  • @fathimaraihana2899
    @fathimaraihana2899 Год назад +1

    Really superb..no wrds to say thnks

  • @purpleheart3064
    @purpleheart3064 Год назад +1

    Nice video... cell signaling is a large and complex topic ...but this made it easy to understand 👌

  • @jyothikoppula5853
    @jyothikoppula5853 Год назад +1

    Nyc explanation ...Thank u

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Год назад

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @wamiqfarooq7401
    @wamiqfarooq7401 Год назад +1

    I love you man.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Год назад

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @emanagoory5282
    @emanagoory5282 2 месяца назад +1

    Many thanks

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 месяца назад +1

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

    • @emanagoory5282
      @emanagoory5282 2 месяца назад

      Yes with pleasure

  • @dipshikharoy3757
    @dipshikharoy3757 2 года назад +1

    Great 👌

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @rahmaayu6877
    @rahmaayu6877 4 года назад +2

    in smooth muscle cell, is there any guanylyl cyclase take action for cGMP forming??

    • @fepifig
      @fepifig 3 года назад

      I dont know in english, but: fosfodiesterase tipo 5.
      It turns GMPC into GMP. its also inibited by Viagra (sildenafil)

    • @joyganguly6834
      @joyganguly6834 2 года назад

      The NO that diffuses out across membrane,bound to guanylyl cyclase of the target cell, which helps in formation of Cyclic GMP from GTP, and later the Cyclic GMP play its role as second messenger and so on.

  • @abhijeet3664
    @abhijeet3664 5 лет назад +3

    Sir please do a review on Question Paper as less time is available
    Or make Question Discussion Topic Wise

  • @atharvigupta4250
    @atharvigupta4250 Год назад +1

    could you share about erectile dysfunction through this pathway too?

  • @aupsornsawansiriphanitsaku8054
    @aupsornsawansiriphanitsaku8054 2 года назад +1

    Thank youuuuuuuu

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 года назад

      Please share my channel link with your friends and help me to reach big audience and to

  • @prabhrit
    @prabhrit 4 года назад +1

    So nice

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 года назад

      If you like my explanation please share among your friends and help me to reach big audience

    • @psandbergnz
      @psandbergnz 4 года назад +1

      @@animatedbiologywitharpan, at 2:57 minutes you say: "the smooth muscle cells are innervated by several blood vessels." You do realise that your statement doesn't make any sense, don't you? Blood vessels don't innervate, nerves do. Your video doesn't show what causes the release of ACh to stimulate endothelial cells to make NO. So, how does the endothelium "know" when to make and secrete NO?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 года назад

      @@psandbergnz Thanks for the criticism, I meant to say smooth muscles are innervated by blood vessels (ya after listening to 2.57 it sounds a bit stupid biologically). Maybe I would make an elaborated video on this topic, it was just an overview for broad audiences.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 года назад

      @@psandbergnzSandberg your feedback is valuable and it would help me to improve the content in the future. thanks again

  • @dentist778
    @dentist778 Год назад

    Why Nitric Oxide drug cause tachycardia and how?

  • @HT.100
    @HT.100 2 года назад +1

    GQ or GS receptors?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 года назад

      None actually...cGMP effect depends on the expression of a cell-specific cGMP-receptor protein in a given cell type

  • @soniaoghroro
    @soniaoghroro 8 месяцев назад

    ❤️❤️❤️

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  8 месяцев назад

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @ameenullah3584
    @ameenullah3584 3 года назад +1

    Plz tell source name sir

  • @salmanah2518
    @salmanah2518 Год назад +1

    Please iam need lectures or references for postgraduates PhD students

  • @diksha1729
    @diksha1729 5 лет назад +1

    Thank u
    Par kya aap hindi m bhi video upload kr sakte h plz

  • @Sk_775
    @Sk_775 3 года назад +1

    I didn't get much 😒

  • @Holypikemanz
    @Holypikemanz 2 года назад +3

    Cant understand your goofy af accent.

  • @TanTan-ch3vq
    @TanTan-ch3vq 21 день назад +1

    One error for acetylcholine injection is not intra muscle cell injection, it is intramuscular injection

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  21 день назад

      its just a cartoon, and emparical drawing. but thanks for pointing out. we will try to be even more accurate next time