Ras Raf MAPK Pathway and Cancer | Mutations, Cancer Pathogenesis, and Chemotherapy

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  • Опубликовано: 30 янв 2025

Комментарии • 36

  • @nicktokar2459
    @nicktokar2459 5 лет назад +21

    14-91% that range is absolutely massive

  • @tasbirmiah5247
    @tasbirmiah5247 9 месяцев назад +1

    YOU'RE A LEGEND I FINALLY FOUND WHAT I NEEDED. THANK YOU. I WAS TRYING TO FIND A MECHANISM OF ACTION AS TO HOW BRAF GENE MUTATION CAN AFFECT MELANIN PRODUCTION AND I FINALLY FIGURED IT OUT.

  • @caramelizedonion6199
    @caramelizedonion6199 3 года назад +5

    very informative and well made video. Thank you!
    Just one thing that might not be completely right: -mab is the suffix/ending for any kind of therapeutic antibody (Monoclonal Anti-Body) and not exclusively for those that target the EGFR.

  • @AymaraAnahi
    @AymaraAnahi 3 года назад +9

    very clear and concise! made understanding a difficult topic much more achievable!

  • @suyasimatele
    @suyasimatele 8 месяцев назад

    Great video. Very simplified, easy to understand

  • @divyanshikarmani
    @divyanshikarmani 5 лет назад +5

    Thank you for the helpful prep for my finals! :)

    • @medicojingle8416
      @medicojingle8416 4 года назад

      ruclips.net/video/kWHgDLYaj_4/видео.html

  • @TheBluebloop
    @TheBluebloop 2 года назад

    this and the video before helped so much. thank you!! great work!

  • @poecilia1329
    @poecilia1329 2 года назад

    Thank you so much for uploading this video!

  • @abdullahnafea4736
    @abdullahnafea4736 2 года назад

    Very clear and informative. Thanx

  • @VincentFoulonnneau
    @VincentFoulonnneau Год назад

    Thanks it is very clear ! What are your sources to give these percentage of cancers ?

  • @vicktorshushackov3074
    @vicktorshushackov3074 2 года назад

    Guy you're cool. Thank you so mutch, it's very needful job that you do

  • @internalmedicine9982
    @internalmedicine9982 3 года назад

    This is a fantastic video

  • @mishalchaudary004
    @mishalchaudary004 4 года назад

    Excellent explanation💞💯

  • @Flaschenente
    @Flaschenente 3 года назад +1

    Thank you for sharing this excellent lecture

  • @olalalin5566
    @olalalin5566 4 года назад +1

    Could you share the literature of H-Ras mutated in bladder cancer. Thank you.

  • @shbangash437
    @shbangash437 4 года назад +1

    Hello sir . Can you please recommend a book from which you prepare all the pathways .

  • @tahaagajani1755
    @tahaagajani1755 3 года назад

    That was such a incredeble video thakns!❤

  • @je6874
    @je6874 6 лет назад +4

    What about the other EGFR-related proteins like HER2? Great video regardless!

  • @helendodwell800
    @helendodwell800 3 года назад

    could there also be mutations in RAS proteins to stop the activation?

  • @cristinepontes9348
    @cristinepontes9348 3 года назад

    thanks for the great class

  • @maydupnem9994
    @maydupnem9994 4 года назад

    interesting, but which source did you use?

  • @MuhammadJunaidAshraf
    @MuhammadJunaidAshraf 4 года назад +2

    what about breast cancer from EGFR over expression? am I missing something or you didn't mention it?

  • @ikbaliremalkan4315
    @ikbaliremalkan4315 4 года назад

    very well explanation ! thanks

  • @erdelyiinnovaciosmuhely2008
    @erdelyiinnovaciosmuhely2008 3 года назад

    Great!
    May I underline a small mistake?
    Hematopoietic, not Hematopoetic.

  • @felixromer4335
    @felixromer4335 3 года назад

    there are 4 not 3 ras proteins. KRAS is devided into KRAS4A and KRAS4B because of different spleißing

  • @silviamoraleslopez9617
    @silviamoraleslopez9617 2 года назад

    could you tell me the bibliography?

  • @sylvesterhomsy1127
    @sylvesterhomsy1127 5 лет назад

    Hairy Cell Leukemia has the most BRAF mutation

  • @evamathebula4448
    @evamathebula4448 6 лет назад +1

    how can RAS be used to treat cancer cells

    • @mariahfoley2499
      @mariahfoley2499 5 лет назад +1

      If you block or inhibit RAS then it will stop the pathway and the transduction signal in nucleus will not be made. Thus decreasing cell proliferation and metastasis aka DEAD CANCER CELL

    • @medicojingle8416
      @medicojingle8416 4 года назад

      ruclips.net/video/kWHgDLYaj_4/видео.html

  • @fernsader9261
    @fernsader9261 5 лет назад

    Where are you pulling all this info from? What studies lol

  • @paulawad9585
    @paulawad9585 7 лет назад

    are u canadian?? ur accent sounds super canadian lol