Very good video. It demonstrates how many moving parts are involved in cancer and why most drugs fail to control it. We just do not know enough of the incredible complexity involved in cancer development
I found this video extremely helpful, it has provided a basis about signaling within a cell. I would recommend this video to someone wanting to brush up on intracellular signaling.
umm --the video says that overexpression of Growth factor receptors causes ligand independent firing - id look over that one more time Its more likely structural mutations to the tyrosine kinase receptor cause ligand-independant activation while overexpression, on the other hand, causes hyper proliferation in basal levels of growth factor
When the receptors are over expressed, the Monomers of receptor tyrosin kinases will interact with each other due to the abundance of the receptors on the plasma membrane. Thus, the overexpression of the receptor will lead to the activation of these receptors by each other by means of transphosphorylation(biochemically speaking-biologically speaking autophosphorylation), giving the cell an oncogenic power.making the cell mitotically active irresepective of the ligand presence. (ligand independent firing).
Seems to me like a promotional video of how well they are doing. Which is fine even if it's not true. But not fine if, "not true", holds up some other research which is.
+Yessi Perez ... or at least a way to tame and regulate cancers. Sometimes a mass of fast-replicating cells can come in handy, but we would still need a way to tell them when and where to stop or slow down, and tell them not to metastasize.
![The Cell Cycle (and cancer) [Updated]](/img/1.gif)
Ah yes of course, I understood everything.
*rewinding intensifies*
Very good video. It demonstrates how many moving parts are involved in cancer and why most drugs fail to control it. We just do not know enough of the incredible complexity involved in cancer development
pretty dope series about the cancer mechanism! trully enjoyed it.
This was just a great video !!! thanks for editing, producing and thanks for people on sharing!
I found this video extremely helpful, it has provided a basis about signaling within a cell.
I would recommend this video to someone wanting to brush up on intracellular signaling.
Amazing high quality video!!! Thanks so very much for creating it!
this is just EPIC and extremely awesome , i really can`t tell how i loved that series . excellent work INDEED
Nice video, it explains how the body can heal itself if we give them good balanced nutrition.
Thank you for this amazing and very pratical vidéo.
Excellent video! Now THIS is a good way to learn. Keep up the good work :)
extremely instructive...thank you
Very good! I was able to learn more
Transforming Growth Factor Alpha, Not Tumor Growth Factor Alpha. Tumor Growth Factor Beta, Transforming Growth Factor Alpha.
Very good explanation
ultimate and outstanding video.
Great video
Thanks a lot! Excellent video!
Yes Yes Yes Sir💖💖💖 GooooooD 💚💚
very very very well explanation
Where can I find transduction pathways associated directly with gene expression and regulation?
Awesome explanation :-)
Thank you for a great video
super nice video!!
Fabulous
Thanks! uploader
The animation is excellent and the explanation are clear but very unstructured. It was hard to take notes while watching
The animation is way too good.
thank you
great vid
Thanks 👍👍
thank you so much
Can someone please suggest some good introduction textbooks about general cancer biology?
thank u soo much.......
superv explaination :)
Great.
thank u
umm --the video says that overexpression of Growth factor receptors causes ligand independent firing - id look over that one more time
Its more likely structural mutations to the tyrosine kinase receptor cause ligand-independant activation while overexpression, on the other hand, causes hyper proliferation in basal levels of growth factor
When the receptors are over expressed, the Monomers of receptor tyrosin kinases will interact with each other due to the abundance of the receptors on the plasma membrane.
Thus, the overexpression of the receptor will lead to the activation of these receptors by each other by means of transphosphorylation(biochemically speaking-biologically speaking autophosphorylation), giving the cell an oncogenic power.making the cell mitotically active irresepective of the ligand presence. (ligand independent firing).
nice one
Introduction to Cancer Biology (Part 1): Abnormal Signal Transduction
great !!!
Seems to me like a promotional video of how well they are doing. Which is fine even if it's not true. But not fine if, "not true", holds up some other research which is.
I hope someone finds a cure some day
+Yessi Perez ... or at least a way to tame and regulate cancers. Sometimes a mass of fast-replicating cells can come in handy, but we would still need a way to tell them when and where to stop or slow down, and tell them not to metastasize.
Trinitrophenylnitramine just stop eating anything
Great!
awsome
Interesting
trying to wait until they mention mitochandia....when????
Cell antenna
can anyone let me know, what does he say in the 50th minutes? solid .... molecules,
thank you
"...extracellular matrix components, or cell adhesion molecules."
When your lecturer is useless... go to youtube >,
Because they hav seen better ones..which are much more clear..
❤❤
Want arabic translation please
nice
Solution :
*Dr Otto Heinrich Warburg* German MD physiologist and biochemist, Nobel Prize for Physiology or Medicine in 1931:
*>*
Very good explanation
thank you
thank u