Cystectomy Alternatives for Bladder Cancer | BackTable Urology Clips

Dr. Bagrodia, Dr. Clinton, and Dr. Pietzak discuss alternative treatments for high-grade T1 bladder cancer patients who are unable or unwilling to undergo cystectomy. The question of what to do for patients unfit for cystectomy is posed. Dr. Clinton the utilization of gemcitabine and docetaxel intravesically, along with FDA-approved options like Val Rubicon and pembrolizumab. Dr. Pietzak emphasizes the potential of chemo-radiation for very high-risk patients and advocates for clinical trials combining immune checkpoint inhibitors with intravesical agents. The dialogue highlights various considerations and opinions on treatment preferences and the complexities of managing high-risk bladder cancer cases.
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