Type III hypersensitivity (immune complex mediated) - causes, symptoms & pathology

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  • Опубликовано: 23 июл 2024
  • What is Type III hypersensitivity? Type III hypersensitivity describes when antigen-antibody complexes deposit in the blood vessels and cause subsequent inflammation and tissue damage. Find our full video library only on Osmosis: osms.it/more.
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    © 2024 Elsevier. All rights reserved.

Комментарии • 127

  • @Ryoko48
    @Ryoko48 5 лет назад +396

    I've watched a few of your videos, now everytime I refer to cell degranulation, I have a visual image of a cartoon cell vomiting out granules and enzymes hahahaha. Your illustrations are great

  • @LiquidSwords007
    @LiquidSwords007 4 года назад +109

    The best thing about this video is that there is special emphasis on the difference between type 2 and type 3, something that confused me a lot

  • @josesolorzano2669
    @josesolorzano2669 5 лет назад +63

    "not to play with snakes" that part killed me XD I love these videos so much

  • @osmosis
    @osmosis  5 лет назад +94

    Hi everyone, we've updated this video to correct a minor error.

  • @bettinafratto1472
    @bettinafratto1472 3 года назад +16

    Quick informative and to the point. Great examples and great stress on the differences b/n II and III types. Thank you

  • @minatsukinana2761
    @minatsukinana2761 4 года назад +19

    Cant thank you enough *-* I always start with your videos before i read my lectures 💜

  • @syedsaber9666
    @syedsaber9666 Год назад +16

    3 major differences btw type 2 and type 3
    *Cell surface bound and atigen ab complement system with soluble antigen
    *complement proteins are synthesize in small amount in 2 and in large amount in 3
    *clinical symptoms corresponds to tissue on interacting with antibody in type 2 and in type 3 it is due to deposition of immune comples (ag ab )

  • @ikramzz701
    @ikramzz701 5 лет назад +95

    7min more interesting than 1hour and half spent with my teacher in the medical school.

  • @cacarew544
    @cacarew544 5 лет назад +6

    Thank u so much. It helps me to have a clearer picture of hypersensitivity

  • @dhuhachouchen6145
    @dhuhachouchen6145 3 года назад +2

    thank youuuuu your videos made my life as a medical student much easier and fun

  • @gomotsegangngwako6762
    @gomotsegangngwako6762 Год назад +4

    Detailed yet brief, its brilliant. I watched videos on the three types of hypersensitivity except type 4, can you please direct me to it if its available.

  • @dayhanaaldave2193
    @dayhanaaldave2193 4 года назад

    I really love this, no se me da mucho el ingles, pero sus videos son realmente buenos, todo esta super entendible. Thanks youuu💜

  • @melylacheb
    @melylacheb 9 месяцев назад +5

    Life savior as always 🤩✨. I will pass my immunology test this week and u litterally resuled a 1 h lecture in 7 minutes sucessfully 🎉

    • @osmosis
      @osmosis  9 месяцев назад

      We hope it went well! 🙏🏼

  • @guljafari3269
    @guljafari3269 4 года назад +2

    thank you very helpful everytime

  • @34jayalakshmi36
    @34jayalakshmi36 5 лет назад +10

    You r the reason for me to study path...pls upload all pathalogy video

  • @Be1smaht
    @Be1smaht 3 года назад

    That was great as usual

  • @emanuele2398
    @emanuele2398 3 года назад

    Amazing thank you!

  • @radhekrishna_lifeline_thak6809
    @radhekrishna_lifeline_thak6809 5 лет назад +10

    I LOVE YOU OSMOSIS.... FROM INDIA.. 😀😃😃💟💟💟💟

  • @elladaye2100
    @elladaye2100 2 года назад +3

    Such a great video to understand these hypersensitivities

    • @osmosis
      @osmosis  2 года назад

      Glad you think so, Ella! 😊

  • @user-um1fe2fd6b
    @user-um1fe2fd6b 2 года назад

    Amazing expalantion
    Thank youu really !!

  • @abdurrehmantayyab9785
    @abdurrehmantayyab9785 Год назад +3

    Very good explanation. Sorry to say but i didn't find type 4 hypersensitivity reaction.

  • @nouhahassam3667
    @nouhahassam3667 3 года назад +1

    I love you guys , thanks for making it easy and interesting

    • @osmosis
      @osmosis  3 года назад +2

      Thanks for watching! 🥰🥰🥰

  • @robertvega5467
    @robertvega5467 3 года назад +2

    una cosa que haria que muchas nos suscribieramos es que cuando estemos en su plataforma tambien podamos poner subtitulos en español

  • @zubairkkkakar296
    @zubairkkkakar296 2 года назад

    Very good explanation has been given in this way, it is understandable by explaining ..very nice video very well understood

    • @osmosis
      @osmosis  2 года назад

      Glad you liked it! 😊

  • @allaboutmovies4821
    @allaboutmovies4821 3 года назад +5

    "Which ultimately teaches a person not to play with snakes" that had me laughing thank you guys.

  • @enoch9019
    @enoch9019 5 лет назад +7

    The unsung heroes of RUclips🙏🏾🙏🏾🙏🏾

  • @arinarakhteenko579
    @arinarakhteenko579 2 года назад

    You’ve made awesome videos thank you so much!!

    • @osmosis
      @osmosis  2 года назад

      Glad you like them! 🙌🏼

  • @ditodewantoros04
    @ditodewantoros04 5 лет назад +1

    Sry may i ask, why does neutrofil cant fagocyte immune complex? Thx.

  • @miranmuslem
    @miranmuslem 11 месяцев назад +1

    Thank you for the amazing video!

    • @osmosis
      @osmosis  11 месяцев назад +1

      🤓🩺 🙌🏼

  • @akanshawadekar7430
    @akanshawadekar7430 3 года назад

    Thank you so much

  • @zoechang7528
    @zoechang7528 2 года назад

    So clear and easy to remember with cute image

    • @osmosis
      @osmosis  2 года назад

      Thanks so much 😊

  • @deffousiheb5031
    @deffousiheb5031 Год назад

    hi ... first i want to say thank you for your explications .... they'r awsome ... but i have a question .... opsonines will bind to immune complexe or endothelial cells or both ??

  • @user-rz6xn4nn2s
    @user-rz6xn4nn2s 5 лет назад +1

    Awesome in awesome way

  • @lilmamasofly9111
    @lilmamasofly9111 4 года назад

    Awesome!

  • @nargismalik6293
    @nargismalik6293 2 года назад

    Thank you for the amazing videos

    • @osmosis
      @osmosis  2 года назад

      Always our pleasure. Nargis! 🙌🏼

  • @Taypha1914
    @Taypha1914 3 года назад

    Your the GOAT my bro

  • @alexandrerebmann203
    @alexandrerebmann203 Год назад

    Amazing video thank you so much

    • @osmosis
      @osmosis  Год назад

      Always our pleasure, Alexandre! ❤️

  • @rashamohammad2170
    @rashamohammad2170 3 года назад

    informative 🍁

  • @amylouise3789
    @amylouise3789 8 месяцев назад

    I am unfortunately suffering from arthritis due to a type III reaction.
    Is there any way to reverse the reaction? I’m about 15 months post the initial onset/reaction to Plavix but still have joint pain!

  • @sumitrajpurohit7657
    @sumitrajpurohit7657 3 года назад

    Thanks....love from BHARAT ( INDIA)

  • @jadkousa294
    @jadkousa294 Год назад +1

    Thanks mate, just saved my ass for my upcoming exam xx

    • @osmosis
      @osmosis  Год назад

      Glad to help, Jad! 😊

  • @malathali8658
    @malathali8658 3 года назад

    عاشت ايدكم

  • @zakayomsigwa2826
    @zakayomsigwa2826 2 года назад

    I have already subscribed . Thanks, much love from TZ. 🙏🙏🙏🙏🙏

    • @osmosis
      @osmosis  2 года назад +1

      Thanks for the sub, Zakayo!

  • @safalechkhab609
    @safalechkhab609 2 года назад

    thank u so much that was helpful

    • @osmosis
      @osmosis  2 года назад

      You're welcome, Safa! 🙌🏼

  • @sachitpatil9061
    @sachitpatil9061 4 года назад

    Perfect

  • @ibrahimmohammed6385
    @ibrahimmohammed6385 4 года назад +2

    U the man

  • @jinuannasabu1242
    @jinuannasabu1242 4 месяца назад

    Pls upload type IV

  • @Nothing-es5nk
    @Nothing-es5nk 5 лет назад

    Awesome

  • @user-my8ps8iu2h
    @user-my8ps8iu2h 6 месяцев назад

    I can't find Type IV hypersensitivity
    Can you diresy me to the link?

  • @zamraabdi3561
    @zamraabdi3561 5 лет назад

    I love u keeep going is the only channel that i'm easy to understand the videos 😍😍😍😍😘😘😘😘

  • @mdzahikhalid404
    @mdzahikhalid404 5 лет назад +2

    Nice lecture.u already mention in early vedeos hyper 1 , hyper 2 hyper 3....i am from india....hyderabad

  • @dr.manishadeol6561
    @dr.manishadeol6561 5 лет назад

    Can u plz tell me about ur osmosis prime?

  • @susanahernandez6893
    @susanahernandez6893 4 месяца назад

    The differences between type 2 and 3, are: complement proteins are synthesize in small amount in 2 and in large amount in 3, clinical symptoms corresponds to tissue on interacting with antibody in type 2 and in type 3 it is due to deposition of immune comples (ag ab ). And the inmune complexes get in the blood vessel, depending in different features: the size of the inmune complexes, the isotype of the Ig, characteristics of the blood flow, the quantity of the inmune complexes and the antigen load (which is possitive).

  • @Kyujinie
    @Kyujinie 2 года назад

    thank u so much

    • @osmosis
      @osmosis  2 года назад

      You're welcome, Alex! 😊

  • @Lina-hi5ji
    @Lina-hi5ji 5 лет назад +3

    Thank you Osmosis. Love from Peru

  • @richardprah1159
    @richardprah1159 Год назад

    Great Video. But i have a question for you.
    Please you made a statement at 4:09-4-11 minute that DNA is cationic.
    I only Know of DNA being anionic from the peripheral phosphate groups. So why did you made that statement that DNA is cationic? And for that case of me knowing DNA is anionic, there would be repulsion between it and the anionic basement membranes.
    Can you clarify what actually makes the dna bind to the basement membrane even though both are anionic. What really happens. I need an answer for this please

  • @alaaadel8900
    @alaaadel8900 2 года назад +3

    *اللَّهُمَّ صَلِّ عَلَى سَيِّدِنَا مُحَمَّدٍ نُورِ الْأَنْوَارِ وَسِرِّ الْأَسْرَارِ وَسَيِّدِ الْأَبْرَارِ، وَزَيْنِ الُمرْسَلِينَ الْأَخْيَارِ وَأَكْرَمِ مَنْ أَظْلَمَ عَلَيْهِ اللَّيْلُ وَأَشْرَقَ عَلَيْهِ النَّهَارُ، وَعَدَدَ مَا نَزَلَ مِنْ أَوَّلِ الدُّنْيَا إِلَى آخِرِهَا مِنْ قَطْرِ الْأَمْطَارِ ،وَعَدَدَ مَا نَبَتَ مِنْ أَوَّلِ الدُّنْيَا إِلَى آخِرِهَا مِنَ النَّبَاتِ وَالْأَشْجَارِ صَلَاةً دَائِمَةً بِدَوَامِ مُلْكِ اللَّـهِ الْوَاحِدِ الْقَهَّارِ.**اللهم صل على سيدنا محمد وعلى اله وصحبه وسلم تسليما كثيرا عدد خلقك و رضا نفسك وزنة عرشك ومداد كلماتك و عدد ما كان وعدد ما سيكون وعدد الحركات والسكون.*

  • @nouhahassam3667
    @nouhahassam3667 3 года назад

    what do you mean by saying that complement levels help you to know about the progress of the pathology

    • @user-jj1nm4sx6w
      @user-jj1nm4sx6w 2 года назад

      I know that the complement system levels help in classifying an autoimmune disease as lupus Erythematous

  • @mohamudabdulkadir7215
    @mohamudabdulkadir7215 5 лет назад +1

    Hi osmosis , why aren't u grouping videos systemic wise at your channel anymore ? Like all videos of CVS in one place and so on.... infectious diseases at one place .
    This will make reaching videos on the same system easier

    • @osmosis
      @osmosis  5 лет назад

      Hi Mohamud, thanks for the interest! Check out our playlists here: osms.it/playlist. These playlists include all of our video content, including complete coverage of physiology and pathophysiology. Many of these videos are not available on RUclips.

    • @Ur1z13l
      @Ur1z13l 5 лет назад

      Not cool removing functionality from RUclips intentionally so people can pay up.

    • @osmosis
      @osmosis  5 лет назад +2

      All of the videos we have published on RUclips are also free to watch on Osmosis.org!

  • @user-jz2nx6xt3t
    @user-jz2nx6xt3t 3 года назад

    You mentioned in your previous video about type two hypersensitivity that the antigen antibody complexes are formed!! 😕 if someone can clarify to me i’ll be thankful

    • @doofenshmirtz4474
      @doofenshmirtz4474 3 года назад +2

      in type 3 hypersensitivity antibodies (IgG/IgM) attach to soluble antigens forming immune complexes that are circulant in the blood. however, in type 2 hypersensitivity tissular/cellular antigens.
      So in both hypersensitivities, there is the formation of antibody-antigen complexes, except un HS3 the complexes are circulant in the blood (immune complexes).
      I hope I helped a little, English isn't my first language x)

    • @user-jz2nx6xt3t
      @user-jz2nx6xt3t 3 года назад +1

      Ha Thor
      Yeah you helped alot ❤️
      I need to go over my notes again so i can gather it all .. thanks🙏🏻
      (English is not my first language either.. lol )

  • @shards8300
    @shards8300 3 года назад +2

    life saver of med and dent students

    • @osmosis
      @osmosis  3 года назад

      Glad to be of help! 😊

  • @doctorjunaid3924
    @doctorjunaid3924 Год назад

    The post streptococcus glomerulonephritis comes under type 3 hs but my question is in this condition antigen is already bound to cells of kidney,shouldn’t it be considered as type 2 bec like u said immune complexes are not considered if antigen is bound to cells .?Anyone has answer

    • @muhammadmuaziqbal
      @muhammadmuaziqbal Год назад

      Antibody is bound to streptococcal antigens and the complex get deposited in the glomeruli. It is not type 2 because streptococcal antigen is not bound to kidney cell, it is a soluble antigen in blood, which later gets deposited. That's my understanding. Correct me if I'm wrong..

  • @115afreen3
    @115afreen3 5 лет назад +26

    Don't play with the same snake twice 🐍🐍

    • @crystalss8354
      @crystalss8354 5 лет назад

      anfere sompink متتت😂😂😂

  • @ShahzaibAli-og6st
    @ShahzaibAli-og6st 2 года назад

    Good

    • @osmosis
      @osmosis  2 года назад

      Thanks, Shahzaib! 🙏🏼

  • @farazahmadnoor6840
    @farazahmadnoor6840 Год назад

    @osmosis... Plz check why this video isn't playable

    • @osmosis
      @osmosis  Год назад

      Hi Faraz! If you're having issues with our videos, kindly contact support@osmosis.org so that our team can better assist you. 🙏🏼

  • @EMTako
    @EMTako 2 года назад +1

    Most important lesson, don’t play with snakes. Lolz

  • @penelopelambson9128
    @penelopelambson9128 4 года назад

    Need a hard copy of this.

  • @foxykira2005
    @foxykira2005 Год назад

    You're website is down?

    • @osmosis
      @osmosis  Год назад +1

      Hi! We don't get to regularly check our comments here but you may send us an email (support@osmosis.org) anytime and our team will be glad to assist you with your concerns. 🙏🏼

  • @anabyakhan160
    @anabyakhan160 2 года назад +1

    Which ultimately teach the person not to play with snakes 😂😂😂😂😂 that was good

  • @user-gn2un1de9n
    @user-gn2un1de9n 5 месяцев назад

    From where i get this notes ??????????

    • @osmosis
      @osmosis  5 месяцев назад

      Hi! We have high-yield notes that you can access over at osmosis.org 😊

  • @sweetta2596
    @sweetta2596 2 года назад

    I just graded 30%/100 cuz of this video. I told to teacher that serum sickness can cause of snake, and he said that "serum sickness causing of snake is impossible. It's other reaction of snake toxicity, u're so wrong." :( guys which one is right ? pls respond me

  • @suriosha
    @suriosha 2 года назад

    ♥️

  • @Arendt-Foucault
    @Arendt-Foucault 4 года назад

    Hahahahaha.. which will ultimately teach a person NOT TO PALY a SNAKE 🤣

  • @mewmannamwem6087
    @mewmannamwem6087 3 года назад

    Bro... my university's "homework giver" sucks .... !@#$ .... why i dont have teachers like this :/

  • @lucian6257
    @lucian6257 Год назад

    Where is type4?🥺

  • @76sohamingavale42
    @76sohamingavale42 Год назад

    Full form of PAN anyone???

  • @fadiwassouf739
    @fadiwassouf739 Год назад +1

    Moral of the story: don't play with snakes

  • @ahmedhesham2096
    @ahmedhesham2096 2 года назад

    Don't play with snakes, noted

  • @mahesm2604
    @mahesm2604 5 лет назад

    There is no playlist ???😐😐😐

    • @osmosis
      @osmosis  5 лет назад

      Hi Human, thanks for the interest! Check out our playlists here: osms.it/playlist. These playlists include all of our high-yield content, not just the videos available on RUclips.

    • @mahesm2604
      @mahesm2604 5 лет назад

      Thank you so much 😊😊😊

  • @adamstonebraker5532
    @adamstonebraker5532 6 месяцев назад

    yo dawg, I heard you like antibodies, so we put antibodies on your antibodies! -Xzibit on serum sickness, probably

  • @Everydayimmoonwalkin
    @Everydayimmoonwalkin Год назад

    Pls don’t tell me type 4 needs that subscription thing

  • @khuziwesithole6719
    @khuziwesithole6719 Год назад

    Why do the cells look so evil😂😂😂😂😂😂

  • @happypaul7966
    @happypaul7966 2 года назад

    serum sickness usmle

  • @user-jj1nm4sx6w
    @user-jj1nm4sx6w 2 года назад

    This video is so incomplete and somethings are not explained good ..

    • @osmosis
      @osmosis  2 года назад

      Hi! Thanks for your feedback. We'd love to hear more from you as to how we can improve our content. If you can, please get in touch with support@osmosis.org 🙏🏼

  • @nablesbenarous9682
    @nablesbenarous9682 7 месяцев назад

    🇩🇿🇩🇿🇩🇿🇩🇿

  • @blackyme2889
    @blackyme2889 3 года назад

    which will teach a person not to play with snikes 😂😂😂

  • @MusicIsMyLife31x
    @MusicIsMyLife31x Год назад

    no type 4? T__T ahh

  • @jinsu0504
    @jinsu0504 Год назад

    text goes on and on 40 pages of gibberish and this guy explains the whole chapter and then some more in just 7 minutes... sigh.

    • @osmosis
      @osmosis  Год назад

      We hope that our video was able to help, Matthew! 🙏🏼

  • @bluemoon78296
    @bluemoon78296 Год назад

    Please speak slower

    • @osmosis
      @osmosis  Год назад

      Sorry about this, Sandra. You may adjust the playback speed of the video by clicking in the cog icon/settings button on the lower part of the video player. 🙏🏼

  • @ghassanauf8103
    @ghassanauf8103 4 года назад

    Try to read your lecture slowly , the best way to learn is teaching , and you’re teaching nothing

  • @leena02nu76
    @leena02nu76 Год назад

    sounds like Type 4 doesn’t exist to him🥲