In case anyone was wandering like me: there is no inherent difference in the mechanism of Friedel Crafts Alkylation vs Acylation. The difference is one is the addition of a alkyl group and the other is the addition of an acyl group. In case you don’t know what that means (I didn’t lol!) an acyl group has a double bonded oxygen whereas an alkyl group does not. Good luck! And thanks for the upload man- this video helped me out tremendously.
The difference is that an acyl group does not undergo rearangement, so if there is a product you need from alkylation, but the group would rearange, simply take an acyl group and after adding it to the ring, break the c=o bond with An acid as said in 17:29 and you are done 🤟🏻
@@nword683 no one asks rearrangement of carbocation in JEE Adv. Its usually a part of a bigger reaction chain. Try advance out, youll whether its "easy as shit"
Thank you so much for all your videos. Honestly I understand everything perfectly when I am watching your videos. Its so helpful and easy explained. Wouldn't know how to write my OC exam without it. Thank you !!
GREAT VIDEO......he always says something that makes me think. You could use the mozingo reduction also to get rid of the carbonyl after acylation. Also for F.C. acylation you need at least a stoichiometric amount of catalyst cause the catalyst form dative bonds forming complexes with carbonyl oxygens (their lone pair electrons) so the catalyst is not regenerated. Throwing some ice water in at the end of the reaction will break the adduct
I Love you so much !!! thank you, thank you, thank you! you are amazing and Your videos are the best !!! I would be dying in my class if weren't for you and your videos. You have such a great talent for teaching. My professor sucks and he loves to waste time he's been driving me mad !!
Your videos are amazing!!!! They help me so much. But the volume is always so low. It's so hard to hear on my computer. When ads go by, they are so much louder than your videos. But anyways thank you for all you do.
Vinyl halides and aryl halides do not react in Friedel-Crafts alkylation. B/C the carbocations derived from those halides are highly unstable and do not readily form. THANKS!
you said that the methyl chloride wouldn't work the first way, but could you use the Acylation method with the ketone oxygen to form a methyl branch on the benzene?!
You mentioned that NO2 will prevent alkylation from occurring, but what about acylation? Can acylation still occur via meta-addition if NO2 is present?
No, it can not occur considering that a nitro group is an Electron Withdrawing group, a positive charge will be resonating. The alkylation is prevented from occurring because positive charge simply does not react with another positive charge. In the case of acylation, you are also forming a carbocation ('+' charge) which will not react like in the case of the alkylation reaction.
Final Exams and Video Playlists: www.video-tutor.net/
In case anyone was wandering like me: there is no inherent difference in the mechanism of Friedel Crafts Alkylation vs Acylation. The difference is one is the addition of a alkyl group and the other is the addition of an acyl group. In case you don’t know what that means (I didn’t lol!) an acyl group has a double bonded oxygen whereas an alkyl group does not. Good luck! And thanks for the upload man- this video helped me out tremendously.
Michael Carnahan and you need an acid like HCl to get rid of the oxygen right?
Good analysis of reaction
The difference is that an acyl group does not undergo rearangement, so if there is a product you need from alkylation, but the group would rearange, simply take an acyl group and after adding it to the ring, break the c=o bond with An acid as said in 17:29 and you are done 🤟🏻
literally the answer I was looking for. Thanks #inorganicexam
Good one mate thx
Wow... How did my prof make this sound so convoluted and difficult... and hearing you explain it it's so straight-forward.
well shit, I'm having this in high school. 0 explanations given.
This question at 11:58 was asked in jee adv 2022! Thanks man i finally understood why propyl benzene is not the major product
This is an eamcet q as well
This is easy as shit brother
If you don't know this then you have issues in rearrangement of carbocation 😊
@@nword683 lmfao
@@nword683he gave jee advanced, you didn't. What's even the point?
@@nword683 no one asks rearrangement of carbocation in JEE Adv. Its usually a part of a bigger reaction chain. Try advance out, youll whether its "easy as shit"
omg I finally understand why highly activating and deactivating groups cause no rxn. thank you!!
Bro you gave me back my confidence ggs brother would never forget you if I get a good college this time
Thank you so much for all your videos. Honestly I understand everything perfectly when I am watching your videos. Its so helpful and easy explained. Wouldn't know how to write my OC exam without it. Thank you !!
this helped me alot !!!!my exam is next week and i was looking to good explanation like that . thanks alot💕💕💕✨✨
GREAT VIDEO......he always says something that makes me think. You could use the mozingo reduction also to get rid of the carbonyl after acylation. Also for F.C. acylation you need at least a stoichiometric amount of catalyst cause the catalyst form dative bonds forming complexes with carbonyl oxygens (their lone pair electrons) so the catalyst is not regenerated. Throwing some ice water in at the end of the reaction will break the adduct
I Love you so much !!! thank you, thank you, thank you! you are amazing and Your videos are the best !!! I would be dying in my class if weren't for you and your videos. You have such a great talent for teaching. My professor sucks and he loves to waste time he's been driving me mad !!
Hydride shift! Right! That's exactly what I needed to know.
Your videos are amazing!!!! They help me so much. But the volume is always so low. It's so hard to hear on my computer. When ads go by, they are so much louder than your videos. But anyways thank you for all you do.
World best chemistry chanel
There is a mistake in 16:22, it is supposed to be tertbutylbenzene instead of isopropylbenzene
他不小心畫錯了 畫太快了八!
@@sensation1162 100%
@@sensation1162 learn english
@@sravanboi4205 youtube has provided the translation feature for a reason.
@@donut8979 humans have been given brains for a more important reason
Amazingly explained. Loved it.
Great..love from india
Vinyl halides and aryl halides do not react in Friedel-Crafts alkylation. B/C the carbocations derived from those halides are highly
unstable and do not readily form. THANKS!
Very helppppfuulllll....
Thanks a lot!😇😇😇
Much appreciate for this video! Will you make another video for intramolecular Friedel-Crafts alkylation and acylation? Thanks!
Thank you once again.
Good Lecture.
It's a nice work thnk u
Thank you very much doctor
your voice man like wow xd really good 👌 lol
your're the best
At 16:30 you went from a iso propyl to t-butyl ...is that correct, I thought only the double bond would form
I'm assuming it's a minor error. Thanks for the video, appreciate it!
Yes there would be formation of double bond; however, it should be tertbutyl, not iso.
brilliant
you said that the methyl chloride wouldn't work the first way, but could you use the Acylation method with the ketone oxygen to form a methyl branch on the benzene?!
Just a quick question... at around 4 minute, Cl- is a really weak base, how does it take H away? Thx!
BELISSIMO!
14:42 Why does the base (Cl-) attacks the hidrogen instead of the carbocation?
Isn't there any general form of these reactions?
Shouldn’t benzene’s double bond present in the form of ring ?
why do we use that form of acyl?
Toooo good
You mentioned that NO2 will prevent alkylation from occurring, but what about acylation? Can acylation still occur via meta-addition if NO2 is present?
No, it can not occur considering that a nitro group is an Electron Withdrawing group, a positive charge will be resonating. The alkylation is prevented from occurring because positive charge simply does not react with another positive charge. In the case of acylation, you are also forming a carbocation ('+' charge) which will not react like in the case of the alkylation reaction.
Will alkylation occur in p-nitro toluene?
No I guess
In which grade are you studying this....
YEAAAAA
I don't understand 😢
audio is low!
Friedel Crafts in practice:
ruclips.net/video/KQZYMfP1IcQ/видео.html
Here's a video for this reaction:
ruclips.net/video/KQZYMfP1IcQ/видео.html
voice always too low
I don't understand 😢