Friedel Crafts Acylation of Benzene Reaction Mechanism

This organic chemistry video tutorial provides a basic introduction into the friedel crafts acylation reaction mechanism of benzene. It explains how to add a ketone functional group to a benzene ring using an acid chloride and an AlCl3 lewis acid catalyst. In addition, it explains how to reduce the ketone into an alkyl group using the clemmensen reduction reaction.
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[@satvikaputcha]

That was very helpful!! Thanks!!

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Love ur methods

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[@shashankchowdhary1784]

I think we have to take alcl3 anhydrous. h2o should not be taken as alcl3 will form coordinate bond with oxygen in h2o rather than cl.

[@Kelly-pf6hz]

Thanks now i can make my favourite cathinones :)

[@Sree613]

Thank you Sir.

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[@OgechukwuFlorence-uj7kx]

This was helpful

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[@reenanwa]

are the reduction methods interchangeable? can i pick and choose?

[@anuvachattopadhyay6331]

Lovely

[@khashayarsarmadi1433]

How does catalyzed hydrogenation (H2/Pd) remove the ketone-oxygen?

[@pragnamamidipaka6154]

Hey! Catalytic hydrogenation of ketones gives alcohols right!

[@atlantascholar9572]

It would be better to start with a tertiary alkyl halide so a tertiary carbocation will be induced which is much more stable?

[@tom_winguill]

1:02 is that benzene or a cyclo hexane

[@WSashy]

It's benzene because he drew the electrons inside the ring (they were blue, maybe a bit difficult to recognize)

[@aliisleem4262]

What name of book you are using?

[@azyle2104]

Probably used many diff books and combined methods and stuff to teach it in his own way

[@nursyahirahsuhaili5527]

hi anyone know why In the experiment synthesis of 4-bromobenzophenone excess of benzoyl chloride and aluminium chloride were used to react with bromobenzene ?

[@wijdanayoub9770]

6:08
How could there still Alcl3 in the solution while it turned into Alcl4 - and reacted with the hydrogen came from benzene previously??

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I did. Here it is:
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[@m_jai3728]

i think you should start representing the bezene with the circle in the middle rather than the kekule structure since it causes confusion

[@proclubsgang8766]

Harder to show intermediates

[@LoneWolf-nt8up]

Then how you do show resonance 😂?

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[@aravindhkumar3976]

Isn't positive charge on a sp2 carbon unstable and doesn't form?

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[@user-fd6tk2vz8n]

You didn't made benzene in the first reaction

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My professor is actually incompetent