Your video popped up to me randomly today. During my undergraduate years, I watched a lot of your videos and they were extremely helpful, especially in the field of chemistry. Once again, thank you for your hard work and crystal clear explanations ❤
Formation of the conjugated double bond system gives extra stability to the molecule.....which is the driving force for that elimination. And like you said OH is a weak leaving group And thus follows E1cb mechanism.
there is one thing that confuses me a lot about aldol condensation reactions, throughout organic chemistry lesson our lecturers taught that OH- is a bad leaving group so we have to hydrogenate it to make it a good leaving group otherwise we cannot make it leave the molecule structure, so i am wondering why in the aldol reactions we do not need to hydrogenate it to separate from the structure? if anyone knows the answer please let me know
usually we say OH- is a bad leaving group and it can only leave when protonated under acidic conditions. but here a carbanion is formed and as we know carbanion is stronger nucleophile than hydroxide so it will push the hydroxide out of the molecule.
Does protonation occur b4 the OH leaves in the condensation part or it leaves as OH? Cus I have been taught it's a bad leaving group and therefore will not leave until it's leaving ability in been improved
Since I have been watching your video, your explanation on this topic isn’t like the others. I couldn’t understand the topic even after watching this video countless times, I had to watch other video before coming back here Not understandable for people who are battling to understand this topic
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I owe my Bachelor's degree in Chemistry to this guy and I have never seen your face. I appreciate you so much.
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i'm in my second years and i think im in your situation too :>
Y'all do this in your bachelor's?? Lmao here we do this in 11th grade
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The best video for Aldol Condensation I found on this entire platform
Thanks
This lecture is so clear! Your work is unparalleled.
You’re a legend I got 88% in my orgo1 thanks to you! Ty so much for your tutorials. :)
this comment inspire me, congrats!
congrats I'm inspired as well ❣
Damn u learned this in orgo1, my school teaches this in orgo 2
@@PriyankPatel-ji4en Also me doing this in Orgo 1. 3 weeks from the exam. Im in Europe, where u from?
@@PriyankPatel-ji4en In india , we learn this in high school
I got 98% for my organic naming test...Thanks to you🎉..🎉...🎉
Your video popped up to me randomly today. During my undergraduate years, I watched a lot of your videos and they were extremely helpful, especially in the field of chemistry. Once again, thank you for your hard work and crystal clear explanations ❤
2 mins into this video my doubt got cleared , ty
this made my life so much easier, THANK YOUU
Everything is clear!!
Dude I think you just saved me for my exam today bless your soul
i have never commented on a video in my life but for my first comment EVER on youtube: i love you organic chemistry tutor
a true lifesaver!!
Rightt!
Where are you from though and what's your field of study?
You’re the G.O.A.T.🙏🏽
You are the best. You really helped me to get get 92% in my undergraduate university chemistry exam
I love the way you teach... thank you!
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the goat of organic chemistry
What happened to the carbon for the final product 14:47?
Wonderful video just asking for clarity!
Yes , there is one carbon missing
thank you for all you do.
Very helpful, thank you.
I was going to kill myself for studying organic chemistry but now I won’t after I understood everything by watching ur videos. :) love u
thank for your brilliant education.but i think in 14:49 the product have to have 6 carbons . please check it
Not 6 , there should be 5 carbon in total in the final product
I always get A in organic.. God bless you.. I can't thank you enough. I pray I become your type one day..
Pls does it form two products or one product
looking forward to see Hunsdiecker reaction mech one day!I been wondering the if its the C=O pi bond or O-Ag's O- attacking Br-Br >
Thanks!
Great Lecture
Thank you for helping me video lecture
12:15 doesn't it resonate with upper carbonyl group and and form alcohol on both side
What the reaction of aldol-croton and ester condensation for 2-methyl butanal.
Thank you 🥷
12:22 I thought OH was a bad leaving group. How are you able to get rid of it?
My TA told me that it's because we're in basic conditions, so it's ok if we eliminate the OH. I don't have a better explanation for it, sorry LOL
j c np. Thanks for responding, regardless
I guess he missed the step in which he protonates the OH to water
Formation of the conjugated double bond system gives extra stability to the molecule.....which is the driving force for that elimination.
And like you said OH is a weak leaving group And thus follows E1cb mechanism.
Ch3- is more basic than OH- so here ch3- is a lot more bad leaving group than oH- so less basicity will be good leaving group
Retro synthesis is quite interesting
thanks this was helpful
at 14:45, why is there no additional carbon to the right of the double bond in the final products??
He froget to put it there, simple mistake.
Very useful piece
Thanks but please how are you to locate the alpha and beta positions
you are the best!!
Why does the H is attacked by the OH- base in the start of the mechanism , is the H acidic? I don’t understand
yes the h is acidic as the resultant intermediate is resonance stabilised
Thank you once again.
Thank you so much, it's helpfull Video
Why do we use heat?
so OH and H can be removed to get final product. sorry i just watched or studying so its not definite answer
if your videos had chapters it would be elite
there is one thing that confuses me a lot about aldol condensation reactions, throughout organic chemistry lesson our lecturers taught that OH- is a bad leaving group so we have to hydrogenate it to make it a good leaving group otherwise we cannot make it leave the molecule structure, so i am wondering why in the aldol reactions we do not need to hydrogenate it to separate from the structure? if anyone knows the answer please let me know
hello have you found an answer yet? -a fellow student with the same question
usually we say OH- is a bad leaving group and it can only leave when protonated under acidic conditions. but here a carbanion is formed and as we know carbanion is stronger nucleophile than hydroxide so it will push the hydroxide out of the molecule.
Thank you
you are amazing! good job!
Thanks 🥺❤❤❤
Good video
why does the nucleophilic carbon attack the carbonyl instead of the alpha hydrogen?
the carbonyl is the electrophilic carbon in this case, which is why it attacks there.
cross aldol rea ??
Does protonation occur b4 the OH leaves in the condensation part or it leaves as OH? Cus I have been taught it's a bad leaving group and therefore will not leave until it's leaving ability in been improved
it's under basic conditions so the OH can't really be protonated
and the reason it leaves is because the carbanion pushes it out, as it's a stronger nucleophile
I recommend watching the Khan Academy...this guy here skips crucial steps
you're amazing
Alors les PC vous êtes prêts pour les concours ?
W vid
3:13 doesnt make sense at all
Since I have been watching your video, your explanation on this topic isn’t like the others.
I couldn’t understand the topic even after watching this video countless times, I had to watch other video before coming back here
Not understandable for people who are battling to understand this topic
💜💜💜
You're definitely alpha, and this video is beta than almost everything else on the topic 👍
You re the best!!!