Immunology | Immune System: Overview

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  • Опубликовано: 5 сен 2024
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    Join Professor Zach Murphy for our overview lecture on the immune system. This lecture will include a summarized and high-yield explanation on the inflammatory process and adaptive immunity. We hope you enjoy this lecture and be sure to support us below!
    Inflammatory Response Video Series:
    Part 1: • Immunology | Inflammat...
    Part 2: • Immunology | Inflammat...
    Part 3: • Immunology | Inflammat...
    Part 4: • Immunology | Inflammat...
    References:
    ● Microbe Online MHC1 and 2 [Digital photo]. microbeonline....
    ● Lumen Microbiology Course [Digital image] courses.lumenl...
    ● Soman N Abraham. ResearchGate [digital image] Retrieved from: www.researchga... 2011
    ● Microbe Notes. MHC function [Digital photo]. microbenotes.c...
    ● Bio LibreTexts. Types of chemicals signaling [Digital photo] bio.libretexts...
    ● Assay Genie. Cytokines [Digital photo] www.assaygenie...
    ● Aun.edu. MCQ Quiz on Immunology [Quiz] www.aun.edu.eg/...
    ● MCQ on Cytokines, Interferons & Interleukins 2021.c [Quiz] www.medicalbio... Immunology:
    ● Oxfor University Press. 2016 Playfair & Bancroft: Infection and Immunity 4e [Quiz] global.oup.com...
    ● Le T, Bhushan V, Sochat M, Chavda Y, Zureick A. First Aid for the USMLE Step 1 2018. New York, NY: McGraw-Hill Medical; 2017
    ● Marieb EN, Hoehn K. Anatomy & Physiology. Hoboken, NJ: Pearson; 2020.
    ● Boron WF, Boulpaep EL. Medical Physiology.; 2017.
    ● Urry LA, Cain ML, Wasserman SA, Minorsky PV, Orr RB, Campbell NA. Campbell Biology. New York, NY: Pearson; 2020.
    ● Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison's Principles of Internal Medicine. New York etc.: McGraw-Hill Education; 2018.
    ● lberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. New York, NY: Garland Science; 2002
    ● Murphy K, Weaver C. Janeway's Immunobiology. Garland Science; 2016
    ● Doan T, Melvold R, Viselli S, Waltenbaugh C. Immunology. Lippincott Williams & Wilkins; 2012
    ● Levinson W. Review of Medical Microbiology and Immunology. Lange; 2012
    Adaptive Immunity Lecture:
    • Immunology | Adaptive ...
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    #ninjanerd #ImmuneSystemOverview #Immunology

Комментарии • 207

  • @laluna5548
    @laluna5548 4 года назад +918

    Is there a Nobel prize for teaching ? I have been watching your channel for over 2 years now. Cannot thank you enough!

  • @gimee0352
    @gimee0352 5 лет назад +291

    Today I passed my immunology exam after many tries, can't thank you enough for your immunology series, it allowed me to understand immunology as a whole, because ALL the topics are intrinsically related here, and I think it's something that doesn't occur in other disciplines where the topics are more independent (not sure if it makes sense for somebody else or it's just me xD) Thanks for making good quality videos, I'm sure it takes a lot of time but it's so much worth it. Thanks again, I really mean it, and keep up the good work, you're awesome.

  • @alissabarcelona479
    @alissabarcelona479 3 года назад +85

    You are helping shape many awesome doctors out of this bunch of Ninja Nerds!!! You are exponentially saving sooooo many lives!!!! The world owes you BIG BIG THANK YOUUUUUs!!!

  • @connorestes9814
    @connorestes9814 2 года назад +49

    I genuinely think that almost solely studying with all of the videos by Ninja Nerd could almost get you through med school. Of course, there is more stuff like certain types of physical examination, internships etc. that one has to learn/go through, but for the theoretical part of med school I’ve almost only studied with your guys‘ videos and passed every single exam (with really good grades, on a side note). Y‘all should genuinely just establish your own med school one day where Professors etc. are trained to teach like you, I‘m 100% sure you‘d have some of the highest graduation and overall passing rates on exams etc. 😂❤️
    I just can‘t thank you enough for the work you all put in to these videos and this channel, you are helping SO MANY people so unbelievably much. You guys are without a single doubt real heroes. Y‘all don’t get anywhere near enough recognition for the so important work that you do. Thank you, really, from the bottom of my heart. You‘re the best ❤️

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  2 года назад +28

      Thanks so much for this incredibly thoughtful comment! Ninja Nerd University - We like the sound of that… 😎

  • @jenniferdugan581
    @jenniferdugan581 4 года назад +22

    You're the only reason I've been able to digest the physiology content in my PT program, I would be wildly confused without your awesome videos. Thank you so much for your amazing teaching!

  • @hansini99
    @hansini99 3 года назад +22

    We all can't thank you enough. I feel so much more confident for my med school exam tomorrow thanks to your videos.

  • @jmmanuelseale1203
    @jmmanuelseale1203 5 лет назад +22

    dude.....listen man...you blew my mind with vast knowledge you have mastered...keep up the great work and studies....you are truly a master

  • @pedrobastos2721
    @pedrobastos2721 3 года назад +7

    I rarely comment on videos, but had to come back here to thank you deeply for your Immunology classes.
    I was barely able to attend any classes during last semester because of COVID complications and I was freaking out the night before my Immunology exam not knowing anything at all.
    Thanks to you I managed to pass. Thank you so much. Amazing videos.

  • @silviagc6070
    @silviagc6070 4 года назад +11

    You are absolutely AWESOME! I've been watching your videos for almost 3 years and I needed to thank you. Great job all the team. And you, Zach are the best teacher!

  • @fredred476
    @fredred476 3 года назад +10

    thanks for taking time to do the summary vid(s). they are really helpful at bringing complex topics together. another great set of lectures.

  • @sarahabling3842
    @sarahabling3842 4 года назад +18

    Intelligence attracts 😍that’s what happened to me ... thank you for making my ongoing pg preparations easy ...love from india 🇮🇳

  • @palaksharma8025
    @palaksharma8025 3 года назад +18

    Iam surviving in medical school ..... just because of this great man!! 🤴🏻 THE KINGG!! ❤️

  • @someone.F.e
    @someone.F.e 4 года назад +8

    You made it in less than 20 minutes!!!!!!! Well done!!!!!! Make sure to get the prize!!!

  • @debbiedebsel
    @debbiedebsel 3 месяца назад +1

    You are an amaziiiiing teacher!! Thank you so much for making these videos. You are truly talented !!!!
    I didn’t understand immunology at all at first just from the uni lessons, but these few videos made it so clear, THANK YOU!

  • @The_hustletown_PA-C
    @The_hustletown_PA-C 4 года назад +4

    I was like dang this guy is either a damn good doctor or scientist....your intro video at PCOM
    popped up on my RUclips to watch feed and I found out that your a fellow PA which makes me love your videos even more

  • @christophermartinez6479
    @christophermartinez6479 4 года назад +5

    Thank you!!! For all your videos (the rest of the team too, not sure who else works on these but you're also appreciated!)

  • @silk.spectre6606
    @silk.spectre6606 5 лет назад +13

    Something I couldn't put together for days, you put into a beautiful story that now makes perfect sense! Thank you for your videos! Thanks to you I get straight As in all my exams! Keep doing it, please!

  • @rwaidaalkhoury5885
    @rwaidaalkhoury5885 6 месяцев назад

    TBH this immunology series cures depression, you describe the entire process with such enthusiasm and love to the matter that it made me appreciate how my very human body fights every second to protect itself :')

  • @bethanytowne2970
    @bethanytowne2970 6 лет назад +38

    dude. this is such an incredible video!

  • @AssafLavie
    @AssafLavie 4 года назад +16

    I'm just here waiting patiently for the episode where he reviews all those back tattoos. Maybe season finale?

  • @phoenixmidekings9333
    @phoenixmidekings9333 11 месяцев назад

    Over and over the best in the field so far, you're a well seasoned tutor

  • @tangogog
    @tangogog 3 года назад +6

    You guys are the masters of teaching! So sorry to find you so late :( Thank you for this beautiful lecture...

  • @tariqhassan7306
    @tariqhassan7306 3 года назад

    I am made at myself why you are not hitting it to million subscribers!!
    No body can match your potential....!!
    Thank you sir,lot of love and respect for you...

  • @KCMDWannabe
    @KCMDWannabe 5 лет назад +5

    Incredible job with this video. Seriously amazing that you're able to provide all of this. It must help with reconciling your knowledge of the topics hey?

  • @asmamajeed7551
    @asmamajeed7551 5 лет назад +2

    Fastest way to cover whole immunology good work keep it up

  • @Tiemsuplo
    @Tiemsuplo 2 года назад

    He is a hero for my medical school journey

  • @rebeccarebecca8880
    @rebeccarebecca8880 11 месяцев назад

    Your teaching style and explanations are amazing!! You get the point across with every video. You should make a video on how you prep and teach. Then you'd have mini-professor Zachs-- worldwide.

  • @yachiapatel
    @yachiapatel 2 года назад

    Can't be more of thankful to this guy for giving such detailed knowledge about immunology ❤❤❤

  • @charmmorningstar7530
    @charmmorningstar7530 Год назад

    u saved me from passing all my bio classes. thank you❤❤❤

  • @wedabdullah3404
    @wedabdullah3404 Год назад +1

    Thankyou Doctor your vedioes helped me so much Im really preciatied.⚘⚘

  • @mussangolo8169
    @mussangolo8169 4 года назад +4

    Men your incredible!!, God bless you these lectures helps me a lot

  • @siaali4057
    @siaali4057 3 года назад

    How can someone be so good at teaching man. Please keep up the good work you're doing. 😭♥️♥️♥️

  • @wolfie5470
    @wolfie5470 4 года назад +1

    Hope the prize was great!
    I've written it many many times but I will do it again - you are THE BEST ♕
    Thank you so much

  • @tarekbarek4407
    @tarekbarek4407 3 года назад +5

    I love your videos! Can you please make a video about the four types of hypersensitivity?

  • @pluto4479
    @pluto4479 3 года назад +1

    Thank you so much. Please complete the series please

  • @sirinesaleh5398
    @sirinesaleh5398 3 года назад

    Hello ninja nerd, first thank you so much for your videos they saved my life.
    Can you make more immunology videos, because a vast subject, and i think many people, other than me need them ( cytokines and chemokines, Dendritic cells, MHC, B-cells development, immunological synapse).
    Thank you deserve so much more recognition.

  • @princetandukar9290
    @princetandukar9290 2 года назад

    Good way to remember the inflammatory mediator chemicals are during this damage "HELP" is releases (Histamine, LEukatrine and Prostaglandins)

  • @tizitageleta1765
    @tizitageleta1765 7 месяцев назад

    i appreciate your teaching style. and i think its better if your videos have subtitles.

  • @nayelimeza6768
    @nayelimeza6768 5 месяцев назад

    you are the reason why i get A's on all my anatomy exams

  • @aayushraj5654
    @aayushraj5654 2 года назад

    Man u are a savoir for me becoz of u only I was able to write all the exams paper so smoothly and that to before a day of studying 😅 thanks a lot ❤

  • @amyyypikaa
    @amyyypikaa 6 лет назад +5

    Just want to let you know, your the reason my semester at my med school has passing our classes :D

  • @alsy1681
    @alsy1681 3 года назад

    Please give this man a Nobel prize

  • @109nazrananazwali6
    @109nazrananazwali6 2 года назад

    Your are the bestest teacher of the world...
    Stay blessed 💖

  • @aparnavenugopalan6108
    @aparnavenugopalan6108 3 года назад

    thank you for making the concepts crystal clear for me...

  • @krishnajagtap130
    @krishnajagtap130 4 года назад +3

    Please make video on hypersensitivity reactions!!

  • @benkim2517
    @benkim2517 6 месяцев назад

    Always love your detailed lecture videos! One thing I haven’t been able to fully understand…
    How do RBCs (anucleated) able to avoid aptosis by NK cells since they lack MHC I molecules?

  • @jeremiahbaker6396
    @jeremiahbaker6396 2 месяца назад

    10:03 Shadow clone jutsu. I always come back to these

  • @user-gd1qw2wc1j
    @user-gd1qw2wc1j 4 года назад

    Very good video for reviewing all the things of inflammatory, Thanks a lot from Thailand

  • @danielva422
    @danielva422 2 года назад

    I could not pass my test without your explanation. Tnx

  • @Arendt-Foucault
    @Arendt-Foucault 5 лет назад +1

    I put all your videos on immune system at 2x, and it was crazy ! Amazing efficiency. I got the recap in one morning, holly shit, it was Great !

  • @zhoisweet2740
    @zhoisweet2740 2 года назад +2

    So did u get the prize ??

  • @BirhaGebre
    @BirhaGebre 6 месяцев назад

    Ninja...Thank you very much your way of teaching is interesting

  • @alsy1681
    @alsy1681 3 года назад

    Give this man our tuition

  • @aayushbatra1147
    @aayushbatra1147 10 месяцев назад

    U DESERVE A NOBEL PRIZE NOT ONLY A PRIZE❤

  • @user-im1my5nh2x
    @user-im1my5nh2x 2 года назад

    Its just like all all all in an only14 minuets
    that's amazing !

  • @bonvoyage3076
    @bonvoyage3076 5 лет назад +3

    Awesome. Good overview, need this for each subject.

  • @brunaiglesias5542
    @brunaiglesias5542 10 месяцев назад

    I think it would be interesting to include in an overview a couple comments on Th1 as well, just a suggestion

  • @happymweemba1260
    @happymweemba1260 2 года назад +2

    this guy is great

  • @fatiahanda3613
    @fatiahanda3613 Год назад

    Ninja Nerd.. your videos are amazing and helpful.

  • @user-ml5co8by4u
    @user-ml5co8by4u 5 месяцев назад

    God-tier overview

  • @b.s.1302
    @b.s.1302 10 месяцев назад

    what prize do you want professor Murphy? since you smashed this so well under 20 minutes :)

  • @madalinacebuc3844
    @madalinacebuc3844 5 лет назад +9

    May I ask a question:
    You said the MHC1 is present on all nucleated cells, as the erythrocytes aren't nucleated, how come the NKcells do not target them or did I get something wrong?

    • @malejacabezas9448
      @malejacabezas9448 5 лет назад +13

      Right. The erythrocytes doesn't have MHC-1 but they express CD47 in their surface (it does the same function).

    • @isidoratasic2058
      @isidoratasic2058 4 года назад +4

      In order for NK cell to kill another cell it has to meet two criteria.
      1. Down regulation of MHC class I molecules
      2. Stress signals from the target cell to the NK which activates their cytotoxic activity.
      Erythrocytes meet the first criteria however they don’t send required stress signals to the NK cells (unless they want to be killed) thus not meeting the second criteria.
      Also they express CD47 marker as mentioned previously which inhibits NK activation.
      Hope this helps!

  • @allykeathley
    @allykeathley 6 лет назад +1

    Absolutely love these videos. Thank you SO much.

  • @anumtassadaq
    @anumtassadaq 3 года назад +2

    thank you, i appreciate your effort

  • @kamyarshahsavani8596
    @kamyarshahsavani8596 2 года назад

    Master of summarizing. 😁

  • @hollymarney4447
    @hollymarney4447 2 года назад

    Please can you do a video on HIV/AIDS love your videos so much!!

  • @duhancigil8302
    @duhancigil8302 3 года назад

    It was very helpful for me to understand this subject. Thank you

  • @sreemahalakshmilakshminara183
    @sreemahalakshmilakshminara183 10 месяцев назад

    Thank you very much for your lectures sir. It is very helpful

  • @gattac900
    @gattac900 5 лет назад +2

    Holly shit that was awesome!!! Brian might explode if watched on typical 2x.

  • @newmanlord7130
    @newmanlord7130 2 года назад

    Zack,
    I have to go to work return and go until evening.l want to vacate my post for the videos in a short time after the second year.
    Hi from Ghana.

  • @SFLARay
    @SFLARay 3 года назад

    brilliant pedagogy!

  • @niswahmuthiah-221
    @niswahmuthiah-221 Год назад +1

    hi prof, can you make a video about hypersensitivity 🙏🤓🙃

  • @mayaa.5987
    @mayaa.5987 28 дней назад

    U should seriously open a university or an academy where teaching is taught… like srsly, i genuinely think u should this is not only a complement its a suggestion

  • @brunaiglesias5542
    @brunaiglesias5542 10 месяцев назад

    This has helped me so much! Thank you!!

  • @faribaabbasyoun1618
    @faribaabbasyoun1618 3 года назад +1

    Amazing lecture 👌🏻👌🏻

  • @labrat7855
    @labrat7855 4 года назад

    Here iam again 🖐😂 watching my review... whenever i have a school lecture reporting, i always come to you.. it helped me alot.. thanks... keep going bro! Godbless

  • @phoebele7585
    @phoebele7585 2 года назад

    Thanks for great videos! Would love a systemic lupus erythematosus review, please!

  • @user-gk9ym4iv5h
    @user-gk9ym4iv5h 2 года назад

    you are my kinggggg!
    did someone summerised all he said and could share it? plssss

  • @popotrou
    @popotrou 3 года назад

    Thank you very much! This is extremely helpful. A great summary

  • @lalanto341
    @lalanto341 2 года назад

    Zach the GOAT!

  • @camilasousa5853
    @camilasousa5853 2 года назад

    This is the best class everrrr!! Thank youThank youu thank youuuu

  • @muhammaddewanggaputralaksa7850
    @muhammaddewanggaputralaksa7850 3 года назад

    thanks for zach and team, i love you guys

  • @aribahbhatti8678
    @aribahbhatti8678 2 года назад +1

    the effort that u put in these videos is just amazing. Thank u so much for teaching soooo good and making my life much more easier

  • @halisai5347
    @halisai5347 4 года назад +1

    Fantastic lectures, excellent job dude~

  • @phoenixkats
    @phoenixkats 3 года назад +7

    Quicksilver : I am the fastest man alive
    Flash : Oh really? You don't run fast enough to leave light behind, do you ?
    Meanwhile Zack ( Immunology in 14 minutes stat) : Bring my marker! These noobs need some lessons!!

  • @daminkim7602
    @daminkim7602 5 лет назад +1

    i think Th2 doesnt not release IL6, IL6 is secreted by macrophages and monocytes in response to other cytokines.

  • @whatev3857
    @whatev3857 3 года назад +1

    THANK YOU SO MUCH for saving my ass and bringing my love for science back

  • @meryem-bel
    @meryem-bel 3 месяца назад

    cannot thank youuuuu enouuuugh 😭🤍

  • @nosotress4744
    @nosotress4744 6 лет назад +3

    Great Job- You win!

  • @user-lg4cw8oh9u
    @user-lg4cw8oh9u Год назад

    Thank you very much 😍

  • @user-vk4dn1ku7o
    @user-vk4dn1ku7o 3 года назад

    beautifully explained

  • @stelwart170
    @stelwart170 2 года назад

    Amazing review ❤️❤️❤️, thank you ninjaa

  • @mujib4466
    @mujib4466 2 года назад

    Thank you

  • @edwinkanatie93
    @edwinkanatie93 7 месяцев назад

    Can you make a video on antigen capture, processing and presentation please Zach😢😅

  • @aimsilaon7644
    @aimsilaon7644 5 лет назад

    This is literally the best

  • @user-oc6bn6sc5v
    @user-oc6bn6sc5v Год назад

    Thanks

  • @RNA842
    @RNA842 3 года назад

    Thanks is not enough for ur lectures🙂

  • @alaabelal5752
    @alaabelal5752 4 года назад +1

    Thanks bro💙❤💛

  • @fatiahanda3613
    @fatiahanda3613 Год назад

    please help us with a video on hypersensitivity reaction

  • @milenad.2645
    @milenad.2645 2 года назад

    Thank you so much!