Immunology | Inflammation: Vascular Events: Part 1
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- Опубликовано: 26 сен 2024
- Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
Join Professor Zach Murphy in this four part lecture series where we talk about the physiology of inflammation. In part 1 of this lecture we discuss the vascular events that involve the local chemical mediators, as well as leukocytosis, margination, diapedesis, and positive chemotaxis. We hope you enjoy this lecture and be sure to support us below!
Inflammatory Response Video Series:
Part 1: • Immunology | Inflammat...
Part 2: • Immunology | Inflammat...
Part 3: • Immunology | Inflammat...
Part 4: • Immunology | Inflammat...
References:
● Le T, Bhushan V, Sochat M, Chavda Y, Zureick A. First Aid for the USMLE Step 1 2018. New York, NY: McGraw-Hill Medical; 2017
● Marieb EN, Hoehn K. Anatomy & Physiology. Hoboken, NJ: Pearson; 2020.
● Boron WF, Boulpaep EL. Medical Physiology.; 2017.
● Urry LA, Cain ML, Wasserman SA, Minorsky PV, Orr RB, Campbell NA. Campbell Biology. New York, NY: Pearson; 2020.
● Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison's Principles of Internal Medicine. New York etc.: McGraw-Hill Education; 2018.
● Iberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P . Molecular Biology of the Cell. New York, NY: Garland Science; 2002
● Murphy K, Weaver C. Janeway's Immunobiology. Garland Science; 2016
● Doan T, Melvold R, Viselli S, Waltenbaugh C. Immunology. Lippincott Williams & Wilkins; 2012
● Levinson W. Review of Medical Microbiology and Immunology. Lange; 2012
● Soman N Abraham. ResearchGate [digital image] Retrieved from: www.researchga... 2011
● The University of Western Australia. [digital image] from: www.meddent.uwa.edu.au/__data/assets/pdf_file/0018/3036123/PATH2220-2017-Lecture-4-Inflammation-1.pdf
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#ninjanerd #Inflammation #Immunology
Murphy is a rare and fabulous lecturer. Don't pressure him to go faster to fit the production time or you'll wreck the delivery to the listener.
What pressure ... i thought the video lasted just 5 minutes and when it ended i said what the hell the video seemed 5 minutes long
instead of netflix, i open youtube for THIS, YOU ARE GREAT GUYS!!
me too such a relief right?
@@meganletavish3333 yup
NOT TO OVER-COMMENT "I JUST WANNA SAY THANK YOU FOR MAKING MY STAYHOME LEARNING EFFECTIVE.
Ninja nerd is going to reach a million student subscribers in a few days.
HOW COOL IS THAT! 🤜🤛
I absolutely adore these lectures. I am both an MD and a PhD but limit my activities to electrophysiology here in Italy. Whoever does not appreciate your lectures with the thumb down, either should not be in the field of medicine or simply do not have what it takes to follow any discipline within the scientific spectrum. You are more knowledgeable and much more clear than many professors I have met in the U.S, and Europe.
I refer to you as the "SOLISTA VENETO" di Padova where I had training in electrophysiology and hemodynamics
You should join the Discord! We have some electro-cardio folks and perfusionists who just love to talk ECG case studies! discord.com/invite/Jzd3fYbAa4 or link in the Channel Description
Where are you based in the USA
I would like to meet you
Just say thank you for being such a great blessing to humanity
Nurse practitioner student here. This is helping understand inflammation for my advanced pathophysiology course. :) Thank you so much!!
Jennifer N where are you a student at?
You saved me many times, Zach! And now I am so happy that I can learn the basics of Immunology with you. Our teacher told us we don't have much time during the lessons so she goes through everything very quickly and told us that we have to learn it at home on our owns. Well, it's kind of a waste of time because I was just sitting there and didn't understand anything - it was so quick and she acted like we should get all the stuff that was in her presentation - the activation of complement almost killed me.
We were just staring at her and thought she was crazy, haha. I am sure she is intelligent so much but she probably can't imagine how hard and complicated it is for us to learn and understand because almost everything is completely new stuff.
You, Zach, have a gift and you really know how to explain everything so easily. So many doctors/professors/teachers with 4 degrees should learn from YOU how to teach students.
THANK YOU SO MUCH xoxo
You deserve 10M subs
Just received my grade for my last test on the immune system and Urinary system. I got a B! Ever since I started using your videos as part of my study program, I have been able to make above average grades! Thank you so much for all of your help! ..Reproduction is next!
+Tiffany Selrick So glad we could help Tiffany! Make sure to tell your friends! Keep studying!
@@NinjaNerdOfficial sir plz I can't understand.. If we are giving BCG vaccination to newborn, but instid of that why people are infected by mycobacterium TB, and sir why can't we apply BCG again after some age two or three times, so that long term immunity can be developed against it.
@@haematologistparvaizwar6803 BCG can only be protective against the meningitis and disseminated TB in children. It does not prevent neither the primary infection nor the reactivation of latent pulmonary infection.
- WHO
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Passed my Hematology exam with your other Videos thank you sooo much man. I'm a visual learner and these videos really help me see the info come to life out the book.
I could barely make it through reading the pages in the pathophysiology book I have, and I would start nodding off. You take pages and pages of confusion and turn it into a visual everyone can interpret. Thank you...
god has blessed us with your existence
madrid22j Has God also blessed us with horrible diseases too?
@@Bilbus7 Don't be that person ...
@@raanoooshh9296 A logical and not fond of bullshit type of person?
@@Bilbus7 pfftt why are you being so negative did you step on a lego? You're not logical anywhere bruh.
@@raanoooshh9296 How am I not logical anywhere? Clearly you believe in fairytales too.
This is the best description of this process I have ever seen. This is channel is GOLD. G O L D!
Thank you so much for ALL your efforts. I cannot imagine anybody can ever explain this topic in a better way. The BEST explanation EVER!!!!
I just had to cry because my exam is tomorrow and I hadn't gotten around to this topic until last minute and I'm just so grateful that I can always count on you to explain a topic
Hello Ninja Nerd, I have no words for how grateful I feel to have access to this knowledge! Thank you so much for your work! Due to my ADHD I always struggled with my textbooks and notes reading material and these videos are a big blessing for my visual learner brain! thank you for your efforts!!! I'm getting way more than passing marks in my anatomy classes! Thank you AGAIN! Got bless :)
You don't have ADHD. You were just "too quick" to misdiagnose yourself.
You deserve 10M subs
So true❤
How are they not at 1 million yet?!?!
I wish I could give you more than just one view because you are saving my life while my professor's earning six digits by just reading through the slides. Gosh! Thank You.
Bro I got all the respect for you, but I would like to remind you that at 22:14 P-CAM should be modified as PECAM, which stands for Platelet Endothelial Cell Adhesion Moleclue. As a MD student and immunology researcher from Taiwan, I would like to thank you for producing these high quality videos that provide me and my classmates with plenty of food for thought. Wish you all the best.
You're such a freaking good teacher!
try taking B vitamins (B9 and B12 - this will relieve vascular inflammation. B12 is methylcobalamin) and essential phospholipids (lecithin). Coenzyme Q10 also helps. In one of my videos I talked about the fact that when I was given intravenous cytoflavin (and these are just B vitamins), I felt very good. Then I did not understand why. B12 should be more than 500 according to the test results - then homocysteine will decrease
Yes be careful and read the label because I learnt and I’m nobody in this field that there’s two kinds of b12 methylcobalamin and cyanacobalamin the latter not good I believe.
LONG TIME I STOPPED USING RUclips FOR ANYTHING EXCEPT WATCHING YOUR WONDERFUL VIDEOS. THANKS VERY MUCH FOR MAKING OUR LIFE SO EASY.
I always go to your page, when there's something I dont entirely understand at med school.
Thank you for making these videos!
this is the very first time in my school journey I do understand what I learned from school, You are an amazing teacher, thank you so much
An amazing and unparalleled teacher ever existing on earth.
Love you sir.
How on earth do you remember all this! Absolute legend
You are the best medical content creator I have seen so far, thank you so much for helping in my medical formation Zach, you are a phenomenon.
All the best from Brazil.
i am just in awe of your lectures . They are just very well explained . very methodical
honestly you should get a nobelprize for being able to explain this so easily and clearly
Showing gratitude to the best teacher I've learnt from.
You are AMAZING!
You made margination/rolling along the endothelial surface so much easier to understand! I can't thank you enough!!!
My PhD thesis diverged into the immune aspects of epilepsy and this is a beautiful way to make sure I'm familiar with everything. Thank you Prof
You have a unique gift to make the complicated not so complicated! Thank you for being amazing!!!
Zach and the Ninja Nerd gang. I am an EMT instructor and your presentations are amazing deliveries of information. You're helping me better organize and prioritize info. and understand processes that I would be lost in understanding without Ninja Nerds. Thanks from Rio de Janeiro
Thanks so much!
You're so good at explaining so complicated mechanisms! I passed one exam thanks to another video of yours last week and I think I'm gonna need this video for my next exam this week! 😁 You're awesome! 😊😊
Zach, You are the best lecturer I have ever seen, wish you the best
THIS IS SO HELPFULL!!!!!!!! I am so glad there´s a video of this subject since our lecturer wasn't teaching us this clearly as you are doing!! THAAAAANKS!
I got 83% on my last test because of your lecture videos! :)
Best and easy to understand explanation, thank you !!!!!! Love your work, it's really helping me get through med school.
This was so helpful. I have been watching a lot of videos on inflammation but this made a perfect picture in my head. thanks a lot.
Oh my god, I am in nursing school and currently taking patho and pharm. This totally helped me! Thank you so much, you are the BEST!! Subscribed and gave you a thumbs up! Thank you! Thank you! Thank you! ❤
That's what a real hero looks like.very grateful for this channel .
Thank you 🙏........I can sit for hours...watching & listening. If only this kind of lectures was made this easy in my Nursing Career. You're a excellent Lecturer 👏
you are the best lecturer i have come across, you share your knowledge for free. never selfish. Many blessings
Your videos are amazing, saving me in so many subjects. And it makes just fun to study with your videos. Thanks a lot from a 3rd year medical student!
hats off man, the way he reaches the conclusions, just wow... Thank you very much Sir..
You have helped me so much in understanding topics I never actually understood properly in Med School! Best teacher. Thank you for making these. Have been using these videos to study for primary surgical exams.
I’m not even in med school; I’m just trying to heal from toxins. This is fascinating, and I’ve found out a lot about why this happened to me!
toxins...LMFAO
@@louisprusa9833 That’s funny? Why? I almost died.
Ok, I can't believe he explained this so well 😮
I was trying to study with the help of every textbook I could find, but it seemed damn near impossible and i was feeling like a giant loser, but then I found you. Thank you so much
This was so helpful. I really find the level of detail you give helps me better understand the processes. Thanks heaps!
I seriously sit and watch your videos and SEVERAL times throughout EVERY SINGLE VIDEO I am saying OUT LOUD, "Wow! That is SO COOL!" etc.
The more I learn, the more I want to know.
Vet- student here...
Your videos are truly the best...thank you
This is just speechless... very well explained... you are really talented
Exceptional clarity while still detailing the underlying mechanism of action. Inspiring.
Zac, you are simply the best. Thank you for all the hours you spend on studying and producing these videos for us. a TRUE legend...
Their is nothing that replaces the favor that you do on us.thanks so much prof.Zach.
الله يهديه ويدخل الاسلام , انسان نظيف وصالح 💞💞
Excellent video - you just effortlessly brought four pages of my textbook to life. Thank you!
I swear your lectures are just mindblowing good, you make me start loving immunology
You explain everything so easily to understand. Struggling nursing school student LOVES ninja nerd!!
When you called TNF-alpha a MOFO I just about died. Librarians givin me the stink eye.
Thanks!!
(No, really, thank you! Great info)
Thanks for all your videos. You make something difficult to understand much easier, FUN and EXCITING!!!
Wow....u are a great teacher....
Explanation to immunology basics at its best...!!!
Thanks buddy...
You are the best thing since sliced bread. Your lectures are complete and detailed and answers a lot of the why's in medicine? Thank you, sir!!!
I love you so much! couldn’t pass my exams without you!
My professors could never... Despite reading materials time and time again I couldn't grasp what was going on before watching this 🙏🙏 thankyou
Our immune systems are so cool!! Your illustrations and talk really help to bring the content to life more so than just reading the textbook or listening to a lecture. Thank you so much!
Cf jtguyyf
Fghyh
I can’t tell you how happy I am that I stumbled upon your page! I have a nutrition degree and have been watching your videos as refreshers, but really I’m learning things I never learned in school as well! Thank you so much for making these videos. I’m your newest fan
nutritionist too,
Fantastic content. You're helping me and so many others out with your videos!
YOU LEGEND!!!!!! i passed my compleeete physiology exam including neuro thank you!
Best teacher ever !!!
An expert in Medical Sciences
I absolutely loved this video!! The way you break things down helps me both auditorily and visually learn. I especially loved when you called TNF a “mofo”
Gosh, the medical vocabulary of this guy is mind blowing.
Murphy i really like your work, u've helped alot of people.. thanks alot🤗
I literally end each video wondering how you do it...incredible
If I pass my NBDE1 it will be mainly because of you! ❤ thank you so much for all these videos!
Great video! So interactive, great personality, amazing content. Can't get enough of this...
Note: A correction for 14:30 - Leukotrienes cause smooth muscle contractions, not relaxation (additionally, constrict airways)
Thank you Ninja for Always Available for helping us in our tough time.
how come i dont feel sleepy and i never yawn watching and listening your vids! 😍
This guy is phenomenal. I’m complete layperson and I’m enjoying this sooooo much,
I passed my Physiology exam thanks to this video alone. Thank you!
Hello ninja nerd, first thank you so much for your videos they saved my life.
Can you make more immunology videos, because a vast subject, and i think many people, other than me need them ( cytokines and chemokines, Dendritic cells, MHC, B-cells development, immunological synapse).
Thank you deserve so much more recognition.
You are great and wonderful ❤, I wish you continued Immunology
Lack of information in this era, really suffer us😢
I really like how you teach. All the way from common basics like in this video to 'three decimals-deep' complexer material.
Absolutely love this video! I’m in Patho for my BSN-RN class online (😢 due to low in person student numbers) I can only “understand so much thru VOPP slides. I’m a hands-on/visual/audio person. The drawings make the info flow more comprehensively! So glad I found this channel thru a TikTok nursing student suggestion!
I will be a teacher like you, one day. Thanks for being such a role model for me.
try taking B vitamins (B9 and B12 - this will relieve vascular inflammation. B12 is methylcobalamin) and essential phospholipids (lecithin). Coenzyme Q10 also helps. In one of my videos I talked about the fact that when I was given intravenous cytoflavin (and these are just B vitamins), I felt very good. Then I did not understand why. B12 should be more than 500 according to the test results - then homocysteine will decrease
As always, great videos and info...FYI - Gram (-) bacteria only releases endotoxins when the bacteria dies and the cell wall breaks up because the endotoxins are part of the cell wall. Gram (+) & Gram (-) both can release exotoxins while still alive.
I'm a first year Medical student from India, and this channel is gold for me.
I feel so hyped after watching you explaining the lecture but I do not know what to do next how to keep those info from being lost
You either need to apply it directly (like in a testing or physical assessment) and I would highly recommend rewatching the video. I've used this process to get through my A&P classes. Just watching this series over and over until I can quote it while I'm watching it (or almost) The key to retention is ALWAYS repetition. Emotional attachment helps, but repetition should always be the default. Repetition to the point of "muscle memory" (being able to recall without effort) is the BEST way to hold on to a concept. The secondary (but also very important, path to memory) is understanding. If you can talk your way through it using something like "if/then" statements, you'll be able to remind yourself of what you've learned. If I see swelling, I know that's because of a fluid build up, what causes fluid build up? cytokines that communicate to the inflammatory hormones...etc. I hope this helps. This is the process that got me through A&P and EMT school.
Hence why I'm watching this vid again, even though I've been done with this particular A&P class from about 4 years. Continuing education always requires repetition.
BLESS YOUR HEART THANK YOU FOR DOING SUCH A GREAT JOB! CAN YOU ALSO DISCUSS WOUND HEALING PLEASE!
Aren’t phagocytes the first cells in the inflammatory process? Or to be specific dendritic cells? I don’t understand why it’s mast cells in the video can you explain this please? Thank you
I couldn't imagine that immunology become my favorite subject & watch your immunology playlist with enthusiasm😍😍😍
So comprehensive & well explained! Keep up the good work! 🙌
All I know is you can teach. You come with drawing, you don't take the pic from the book and just to explain you out in the work. I wish I could pay you but for now I send your youtube link in my batch main group so others can watch and learn. Thank you nuff love from Jamaica 🇯🇲
I could not thank you enough for such an incredible lecture! Good bless you....
I can never thank you enough your videos are just amazing please never stop making videos it helps alot🌹
Just writing a comment to help the channel grow
You do great work, thank you so much for everything you've already done. I've gotten really into this sort of stuff 2 months ago because I realized this knowledge allows me to do stuff that really, really helps me in my personal life, so your videos are incredibly useful. Everything else I can find for free on RUclips seems to ultimately just be more or less superficial pop science
video wey dem do 6 years ago o🤣
omg your videos are amazing... i attend all my university classes and all those 2 hour lectures are not even comparable to yours in details and being understandable. i think i never understood these processes this well before and please please for the sake of science and helping med community please continue making videos thank you so much. loves from overseas
MUUUUITO bom, meu caro!! Explicação clara, direta e muito convincente!! Parabéns!!! [I liked very much of your explanation, very clear, thank you, buddy!!!]
Pls make pathology videos🙏🙏🙏🙏🙏🙏
I second this motion!
bro use OSMOSIS for pathology
try taking B vitamins (B9 and B12 - this will relieve vascular inflammation. B12 is methylcobalamin) and essential phospholipids (lecithin). Coenzyme Q10 also helps. In one of my videos I talked about the fact that when I was given intravenous cytoflavin (and these are just B vitamins), I felt very good. Then I did not understand why. B12 should be more than 500 according to the test results - then homocysteine will decrease
thanks ninja nerd for making these videos they are a real life saver, i physiology only beacuse of you
Zacko! You are incredibly different from all other Teachers on RUclips, and you are so young.