Eukaryotic Translation ELONGATION - How do eEF1A and eEF2 work? Role of diphthamide in translation?

References/Resources: / the_crux
What is the process of translation elongation in eukaryotes? How does the 80S ribosome move during translation elongation in eukaryotes? What are the steps in the translocation of 80S ribosome? How do eukaryotic elongation factors help in the translation elongation? Which elongation factors are essential and which ones are non-essential? Are there extra elongation factors? What is diphthamide modification? Find out answers to all these questions in this video:
Jump to your favorite section:
00:00 Outline
01:00 80S ribosome
01:34 eEF1A binding
02:53 Hoogsteen pairing (18S rRNA)
04:39 eEF1A rotation
05:53 eEF5A (special)
07:16 eEF2 binding and Diphthamide
10:10 eEF3 (special)
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[@MrZeiss-cc5tp]

EIF5A, not eEF5A. But still a great video. Thank you.

[@theCrux]

Absolutely! Thanks for the catching the error - will pin your comment so others can notice :)
For anyone trying to find the error, it is at 6:06

[@naadzormomingle6358]

Thanks for the correction. I was a bit confused too😅

[@Divya-qn4rm]

One of the most prominent explanation of translation elongation

[@alejandropikoulasplata5524]

Thank you so much for these great explanations!

[@di3486]

These are going to be absolutely invaluable when I take my prelims. Thank you!!!

[@kanikamahra5839]

Soo helpful ..definitely one of the best videos of molecular..keep making ..keep posting..really appreciate your work👍👍👍👍

[@lisangoie5989]

You are the best , thank you for all your help ❤

[@Ryan-jv9se]

Wow!! Thank you so much for this video! Great explanation.. love the detail! Wish i saw this video when i first learned translation. Thank you a ton!

[@naadzormomingle6358]

Thank you @theCrux for such an informative video. Definitely helped my curious mind

[@Greanestbean]

Thank you for this

[@yashika1456]

Thank you❤