Thank you so much for the video!I have one question. does DNA polymerase also have similar protein as Trigger loop, which allows one nt at a time? as far as I know, trigger loop allows nt one by one for more accurate polymerization. So I am wondering if DNA polymerase has similar functing protein. Again, thank you for your video!!
Excellent question! Yes, there is a structure in the DNA polymerase "palm domain" that functions *similar* to the trigger loop which generates a tight pocket when the correct dNTP base pairs with the template.
Wow. Thanks for such a great video. I'm trying to understand the replication process in a pedantic way. Would you please tell me which text book has provided an in-depth discussion about DNA replication.
Depends on what level you want to study the process - for undergraduate studies something like Watson's Molecular Biology of Gene or Lewin's Gene would be fine. For anything higher, I recommend reading the published literature.
Depending on what level you want to study, there are different textbooks you can refer. For university level, I think Lewin Genes + Molecular Biology of the Cell, are fine... they don't have in-depth discussions but I think if you are looking for textbooks to study for exams or something similar, they are alright.
saving lives!!! thank u so muchh
Beautiful drawing and clearly explained... really nice.
all the love and appreciation form egypt 👍👌
Excellent video brother.
excellent explanations ,keep it up great work✌👌👏👍
plz upload transcription in eukaryote.
Best videos ever.
Thank you so much for the video!I have one question. does DNA polymerase also have similar protein as Trigger loop, which allows one nt at a time? as far as I know, trigger loop allows nt one by one for more accurate polymerization. So I am wondering if DNA polymerase has similar functing protein. Again, thank you for your video!!
Excellent question! Yes, there is a structure in the DNA polymerase "palm domain" that functions *similar* to the trigger loop which generates a tight pocket when the correct dNTP base pairs with the template.
Wow. Thanks for such a great video. I'm trying to understand the replication process in a pedantic way. Would you please tell me which text book has provided an in-depth discussion about DNA replication.
Depends on what level you want to study the process - for undergraduate studies something like Watson's Molecular Biology of Gene or Lewin's Gene would be fine. For anything higher, I recommend reading the published literature.
Tropp
Sir will the NTP always add in the +1 site of template
Please make video on Replication
Sir tell me the reference books , i want to study DNA replication and translation as welll
Depending on what level you want to study, there are different textbooks you can refer. For university level, I think Lewin Genes + Molecular Biology of the Cell, are fine... they don't have in-depth discussions but I think if you are looking for textbooks to study for exams or something similar, they are alright.
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