Oxidative phosphorylation Animation - Formation of ATP & sites of ATP synthesis

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash
📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- t.me/bhanuprakashdr
📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- linktr.ee/DrGBhanuprakash
Oxidative phosphorylation is conceptually simple and mechanistically complex. Indeed, the unraveling of the mechanism of oxidative phosphorylation has been one of the most challenging problems of biochemistry. The flow of electrons from NADH or FADH2 to O2 through protein complexes located in the mitochondrial inner membrane leads to the pumping of protons out of the mitochondrial matrix. The resulting uneven distribution of protons generates a pH gradient and a transmembrane electrical potential that creates a proton-motive force. ATP is synthesized when protons flow back to the mitochondrial matrix through an enzyme complex. Thus, the oxidation of fuels and the phosphorylation of ADP are coupled by a proton gradient across the inner mitochondrial membrane
Oxidative phosphorylation is the culmination of a series of energy transformations that are called cellular respiration or simply respiration in their entirety. First, carbon fuels are oxidized in the citric acid cycle to yield electrons with high transfer potential. Then, this electron-motive force is converted into a proton-motive force and, finally, the proton-motive force is converted into phosphoryl transfer potential. The conversion of electron-motive force into proton-motive force is carried out by three electron-driven proton pumps-NADH-Q oxidoreductase, Q-cytochrome c oxidoreductase, and cytochrome c oxidase. These large transmembrane complexes contain multiple oxidation-reduction centers, including quinones, flavins, iron-sulfur clusters, hemes, and copper ions. The final phase of oxidative phosphorylation is carried out by ATP synthase, an ATP-synthesizing assembly that is driven by the flow of protons back into the mitochondrial matrix. Components of this remarkable enzyme rotate as part of its catalytic mechanism. Oxidative phosphorylation vividly shows that proton gradients are an interconvertible currency of free energy in biological systems.
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[@doctorbhanuprakash]

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- instagram.com/drgbhanuprakash
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📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- linktr.ee/DrGBhanuprakash

[@abdullah84290]

Sitting here in great distance cannot do more than thank you!

[@doctorbhanuprakash]

most welcome

[@medics4416]

Thank you so much sir for this video... After 15 days my xm r there and this video helped me a lot... Ur way of explaining along with animations is fantastic....🙏🏻🙏🏻

[@doctorbhanuprakash]

Tysm 😊

[@darshitasoni9310]

Thank you so much sir🙏💕... Very clearly made me to understand dis... Tq

[@gabrielepeham2576]

Thank you! Very clearly! 👍

[@senor.organic5982]

Greatest video on the topic period! Thank you! 🙌🙌

[@doctorbhanuprakash]

🤝🤝🤝

[@vismayikaryamsetti]

That was so deep and crystal clear. Thank you so much.

[@doctorbhanuprakash]

Glad it was helpful!

[@jyotshnabiology3419]

Thank you so much sir . God bless you

[@theplanechannel3133]

Thank you so much doctor. I didn't understand a thing thought by my lecturer but u made it all so easy. May God bless you

[@doctorbhanuprakash]

Ur most welcome

[@NeelGulati]

thank you for your help!!

[@chemistverse7141]

Very well explained...! Highly appreciated 👍💯

[@doctorbhanuprakash]

Tysm

[@d.saikeerthi57]

Thank you so much sir u explained me very clearly and easy to understand the tough topic.

[@doctorbhanuprakash]

tysm

[@pateltapasvi7277]

Your animation and explaination in very very good thank you for this video

[@doctorbhanuprakash]

🤝🤝🤝

[@plantscienceswithprasanthi1834]

Super explanation sir........so clear and understanding easily

[@doctorbhanuprakash]

Thank u so much 🤝🤝🤝

[@AliHassan-lh2or]

Thank you so much doctor I am very grateful to you ❤

[@doctorbhanuprakash]

🤝🤝🤝

[@vinaysingh1452]

Very nice animation vedio ... best learning of oxidative phosphorylation..

[@doctorbhanuprakash]

Glad you liked it

[@CindySimoonga-ix1ef]

Thank you so much!!.
You just saved my life and degree!.

[@doctorbhanuprakash]

Great to hear

[@MuhammadYasin-ej1ow]

Amazing sir g 👍
I am a medical student but before this lecture I can't realize the mechanism of oxidative phosphorylation but now I have full command on this topic this is just because of you
A lot of thanks ❤

[@doctorbhanuprakash]

Most welcome

[@neelamthakur3175]

Waoooo u r great sir ...excilent teaching ..u made this topic very easy to understand

[@doctorbhanuprakash]

Tysm

[@kalsoomhussain9582]

you are doing a Great job sir
thankuuuu so much for helping us

[@doctorbhanuprakash]

Thanks and welcome

[@tanishadarolia4322]

No words to explain ur explanation and efforts

[@doctorbhanuprakash]

Thank you so much 😀

[@DuaFatima-vf5rs]

Thank soo much I don't have words to thank you....doctors save life of others and you dear sir save doctors

[@doctorbhanuprakash]

Thank you so much

[@krishnapriyapal]

Thank you sir for this amazing lecture..it clear all my doubts in this topic...

[@doctorbhanuprakash]

You are most welcome, keep watching

[@doctorbhanuprakash]

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[@parthsaha5672]

Sir, 10 c subunit is present in yeast, what about humans??

[@pogusrinivas4669]

Sir what confirmational change will take place in beta sub unit

[@93shreelakshmihs]

Sir what form does the energy is liberated from complex 1 3 and 4

[@user-mr5yt5ls1i]

Crystal clear concepts 🎉🎉. Thank you sir

[@doctorbhanuprakash]

Ur most welcome

[@adityaanand8342]

Nice explaination 🙏🙏🙏🙏🙏

[@vokimanh_0294]

Always love you

[@doctorbhanuprakash]

🤝🤝🤝

[@ahmadaaza4779]

@@doctorbhanuprakash 9class ke send kere all is very good

[@pavankumar-ln4ks]

Outstanding information..very very nice explanation sir ji 👌

[@doctorbhanuprakash]

Thanks and welcome

[@sushreetaacharya8522]

Wow ..maja aya sir... concept bhi clarified...👍👍🍀

[@1sHakti.o07]

Mujhe bhi samjhado...I don't understand

[@DactarSab]

Thanku sir g

[@kingtembo6443]

Beautiful Explanation...

[@doctorbhanuprakash]

Tysm

[@rajababukumar4277]

Sr .....your voice is very clearly more understand. Tq sr...🙏🙏🙏

[@doctorbhanuprakash]

So nice of you

[@sangeethabsmh3168]

Thank u sir only u hav come out with correct explanation no video content is depth like urs plz make videos of all botany topics for neet kind request

[@doctorbhanuprakash]

Sure , I will

[@darlingsunshine.2323]

Amazing discussion 👏👏👏

[@doctorbhanuprakash]

Tysm

[@drfaria2000]

Thank you so much.. best channel

[@doctorbhanuprakash]

Tysm

[@vanaparthisuhas7882]

Thank u so much sir

[@akhandbharat1714]

Sir, in photosynthesis PS 1 present on stroma lamelle then how it form atp because H+ concentration in stroma remains constant

[@shanialaroux6614]

it was a great explanation thank u

[@doctorbhanuprakash]

🤝🤝🤝

[@narendrakottapalli7196]

Thank you sir for your excellent explanation

[@doctorbhanuprakash]

You are most welcome

[@ryyadav3997]

Thank u so much sir😊😊 really u make it too easy👌👌👌👌👌

[@doctorbhanuprakash]

Most welcome 😊

[@chintu670]

What is the role of protons(chemically) in ATP production

[@aaashikshabhujel8217]

Oxygen after receiving election combines with 2proton(2H+) to form water, these protons which are involve in production of water is known as proton chemical

[@arpitadasfoodnutrition9980]

Excellent elaboration

[@doctorbhanuprakash]

Tysm ji

[@ZoologyTalks]

Sir ur videos are really awesome and your explanations are crystal clear! Thank you so much for this fabulous work.
I have a doubt related to this topic sir. How many protons are required to activate the F0?

[@rishighai12]

Its not the requirement of fo but depending upon the protons that are pumped back the atp will be synthesized. For eg if 4H+ (proton) are pumped 1ATP will be produced

[@jyotikomal9398]

thank you sir for made it easy for me 👍

[@doctorbhanuprakash]

Most welcome 😊

[@naresh6741]

Thanks sir 🙂

[@doctorbhanuprakash]

Most welcome

[@priyajoseph913]

Thank you sir for such a beautiful presentation..... If I watched this during my graduation time, I would score better marks in biochemistry... Anyway Thank you sir..❤❤

[@doctorbhanuprakash]

You are most welcome

[@akshayasadan]

Thank u sir...

[@doctorbhanuprakash]

Welcome

[@93shreelakshmihs]

Sir how protons will help in Producing ATP

[@colletteikeanyibe1487]

Thanks Doc

[@doctorbhanuprakash]

WELCOME

[@colletteikeanyibe1487]

Please can do a video on biosynthesis of porphyrin

[@vinaymashapogu3325]

Super video sir👏👌

[@doctorbhanuprakash]

Thank you

[@ameetkumar5365]

Thank you so much 😊

[@doctorbhanuprakash]

You're welcome 😊

[@hardeepkaur9269]

Thanku thanku soo much sir for this wonderful lecture thanku sir

[@doctorbhanuprakash]

Most welcome

[@shanmugapandiyan1777]

Thank you so much sir 🤩

[@doctorbhanuprakash]

🤝🤝🤝

[@jt2097]

Did this energy production system need to come into being before the first living cell could exist?
Thank you for the video.

[@doctorbhanuprakash]

Yes

[@jt2097]

@@doctorbhanuprakash Thank you for your prompt response.
Wow, that first living cell must have been some lucky chance. How many billion years would we have to wait for that to happen by accident?

[@hariprabhu9725]

JT look up endosymbiosis theory. The mitochondrion was actually a separate living organism which was engulfed by a larger organism (phagocytosis obviously), and formed a symbiotic relationship.

[@jt2097]

@@hariprabhu9725 we humans have a strange characteristic. Someone has an idea of what might have happened and forward a theory. People then think 'Oh that sounds plausible, that must be what did happen.' A possibility becomes an adopted truth.
How would you describe that characteristic? Gullible, blinkered, believing what you want to believe, believing what makes you comfortable personally instead of persuing the truth?

[@jt2097]

@@hariprabhu9725 You are parroting what you have been taught without thinking which of course you are free to do if you choose to be that kind of person.
When searching for truth a person must do it for themselves, you would reject what I say without thinking because your desire to be right is stronger than your desire to learn.

[@prakashnachinolker610]

Good prestation.I request you to use the pointer again and again to highlight the complexes...in order to have better memory consolidation .Thanks for the lovely prestation by you handsomeguy

[@doctorbhanuprakash]

Tysm

[@rabinmr225]

Sir why cytoplasmic NADH+H produce 2 ATP?(in plants)

[@pralaypati3700]

Thanks Sir

[@doctorbhanuprakash]

🤝🤝🤝

[@DEPTHOFBIOLOGY]

Supper sir

[@DEPTHOFBIOLOGY]

Ur explanation way is awesome sir

[@doctorbhanuprakash]

So nice

[@ihsaanullahshah333-pd3yj]

great love from pakistan faisalbad

[@doctorbhanuprakash]

TYSM

[@AswathyAchu-rh2is]

💯💯💯

[@aaashikshabhujel8217]

Please explain confirmation of Beta subunit and how actually ATP is form

[@shalu6044]

sir
i often get confused b/w ETC and oxidative phosphorylation, is it supposed to be a part of each other
plZ elaborate if possible

[@doctorbhanuprakash]

u can see ETC in my play list which is explained coupled with oxidative phosphorylation

[@shalu6044]

jst got ur suggested video
vl surely come back to u once i'll
go through that
thnkeew so much professor !

[@shalu6044]

watched tons of videos of ur channel
sUbsCriBed sir !

[@doctorbhanuprakash]

@@shalu6044 thats great

[@deebaquadri2752]

Sir can I get notes of this process.Thank you sir your explanation is fantastic

[@doctorbhanuprakash]

Yes, sure

[@deebaquadri2752]

From where I should receive your notes sir.Thank you for replying sir 😊

[@Asquare369]

😍

[@majnoonsafi923]

♥️♥️♥️♥️

[@Godsfavorite903]

Sir make it as app like byjus for medical students

[@doctorbhanuprakash]

yes as medical syllabus is huge , we are planning to release whole mbbs by 2020 june with Animated videos , Lecture notes , MCQs and Cases

[@Godsfavorite903]

@@doctorbhanuprakash thank you for your concern sir.

[@Mysterious387]

Love from Pakistan 🇵🇰❤️♥️

[@doctorbhanuprakash]

Tysm

[@abhaykawde1247]

Oxysome proces ka hindi me video banaeye

[@Kingslayer_29]

If we rest always and oxygen is utilised less then will it mean that we will live a long life as less atp is consumed.. if we exercise we'll consume a lot of atp hence energy used which will make our body unhealthy because of wear and tear ????

[@doctorbhanuprakash]

Yes absolutely 💯

[@Diana-xs4xw]

I think I would never understand these things,give up after not a few amount of trial,anyway thanku

[@doctorbhanuprakash]

Ur most welcome

[@babitachouhan5201]

Iske notes milenge kya sir. Plz

[@babitachouhan5201]

Kha milega sir

[@bhagyalakshmibapanapalli6440]

Hi sir .i need general pathology videos. Can u update please

[@doctorbhanuprakash]

Suree

[@kirannj777]

Thank you sir

[@doctorbhanuprakash]

Welcome