also You can watch Videos related to Mitochondria and Electron Transport Chain (ETC) 1-ATP Synthase Structure: ruclips.net/video/WzqVu8OWedo/видео.html 2-ATP Synthase Mechanism: ruclips.net/video/39UKSfsc9Z0/видео.html 3-ATP Synthase in Action: ruclips.net/video/A2my52zQA6k/видео.html 4-Glycolysis ruclips.net/video/KfWkZZZjMQE/видео.html 5-Citric Acid Cycle (TCA) ruclips.net/video/82CplqKfw90/видео.html
i think the gradient of H ions will power it, because a gradient stores energy (which is also used to transport against gradient as well as along gradient in case of many transporters, e.g as occurs in the secondary type of active transport ^.^ ) im not 100% sure tho, im just thinking :P
@@goosecouple the concentration gradient between the matrix and the intermembrane space forces the protons to enter from the intermembrane space to the matrix through the F1F0 ATP Synthase which makes ATP molecules from ADP and inorganic phosphate "Pi" molecules
@Jay Blake A simpler or more efficient process may exist but it may also be too slow to compete with this complex process. There used to be a simple version of blood but it couldn't support animals thicker than a worm so complex blood with iron was favoured by evolution.
I've heard all my life that mitochondria are power cells, but never understood any explanation using a book at school, this is mind blowing for me, it all makes sense now.
You're likely lying. Textbooks do an excellent job, if not medical textbooks do the job. This video is nice, but nothing beats actual, sanctioned education.
These animations are so much better than dry words alone on a page . Not everyone is good at mental visualization from a written description. I'm a visual learner and seeing things like this help immensely.
I cannot believe what I'm looking at. Imagine the people hundreds of years ago making water wheels and windmills had no idea they were copying the micro-machines that make the body run. Incredible!
This visualization seriously is empowering. Taking otherwise abstract thoughts and making them coherent and digestible, and not only that but actually cool and engaging! Jeez, man.. Everyone who was involved in creating and distributing this lesson, thank you thank you thank!!
I don't know how to help you if this doesn't make you awe inspired. This is going on in your body _right now_ and is the reason you could even watch and remember it. This is beautiful. Thank you for posting.
Excellent! I wish I had had these animations available when I was taking my Biochemistry courses. It would have made things SO much easier! Thank you for the effort you put into these remarkable videos. BB
Proteins are so flipping amazing. I look forward to the day that we can accurately predict and control protein folding. Imagine that; the ability to create a molecule to catalyze any reaction we could possibly think of. I'm thinking the ability to take CO2 out of the air and very efficiently turn it into plastics or fuels, or the ability to easily turn large quantities of CO2 into O2 for interplanetary travel, then the ability to directly synthesize sugars and foods from the Carbon produced. The ability to manufacture more efficient solar panels. Perfectly efficient recycling of waste materials. Factories that produce no pollutants. Mass production of graphene or carbon nanotubes. The ability to cure any diseases and possibly solve aging. The possibilities are endless!
The future is at our fingertips. Its amazing how the politics and economics of controlling ppl has completely stiffled these possible advancements that you spoke of.
This is the best video I've ever seen on RUclips. Seriously. This is what I always hoped the internet would look like... but it didn't. Also, it's pretty funny that you use the word "giant" at the end to describe a mitochondrion. Everything is relative, I guess.
Yeah i didnt know content like this even existed until yesterday and there's actual footage of other small systems here on yt by Science Insider : Award Winning Footage Of The Microscopic World Around Us aaaand Drew Berry: Animations of unseeable biology
Sort of. Physics is the 'fundamental' science from which all others are derived. At the most basic level we are ginormous collections of quarks and leptons.
@@eyescreamcake yes ppl fail to realise this I would site- "math is perhaps the only reliable science we have"-jayahsankara -ancient indian mathematician the statement is pretty powerful as the patterns in maths r the patterns of cosmos
This is a blessing because the only way I seem to absorb information is if I can see exactly what is being described. Thank you for your skills and information!
What I have read and reviewed from several chapters of Stephen White's Physiology and Biochemistry of Prokaryotes for several days have been summarized comprehensively in an 8 minute video. Saying that this video is amazing is clearly an understatement!!! 👏🏼👏🏼👏🏼
The animation and narration made the electron transport chain seem "real" and very understandable. the world is surely better off because of this video. thank you for making it.
I feel so grateful to you, guys! I don't want to imagine how much work it takes to create such a beautiful and informative clip like this! Amazing job!
This is like some kind or revolution in the teaching of science. This is cutting edge stuff. And it's being made very accessible to the general public. If I didn't see it I wouldn't believe it.
Totally astounds me finding that Protons are freely traveling without neutrons and electrons in living matter. These reactions are so complex, they could have never come about by blind chance - this is an amazing part of a cleverly designed factory
Thank you to all the energy spent by those great minds that contributed/ing towards putting together this incredible puzzle. And of course to the people for this awesome presentation.
Wow, I'm at a loss for words! I simply can not comprehend topics like this by just reading a textbook. Animations, however, ellucidate topics and enhances the learning process. Thank you for posting this video.
In contrast to what the video shows, FAD is not a soluble electron carrier but rather is covalently bound to complex II (succinate dehydrogenase). It is succinate (from the Citric Acid Cycle) that delivers electrons to the complex.
@@3omarali Thank you for being willing to admit mistakes! I've argued till blue in the face with some people who have made simple, minor errors in education videos and can't bring themselves to just admit it and fix it.
I don't care how beginner understanding the electron transport chain is. I'm watching (and understanding) a Harvard video, this is as close to a formal education as i have ever come!
@@krinohs David When did I say natural process doesn't occur? If you mean to say evolution? I am not buying it. There is no example of species gaining a new gene, only examples of losing old features or modifying old features with already existing features. There is more proof that it is more like old animals are dying over time than new animals appearing. Each day we see more and more species going extinct. If you know anything about carbon dating, you would know it is getting irrelevant because fossils we are interested in are "too old". It should be impossible for us to find traces of carbon-14 right? Well how about us finding dinosaur flesh and bone marrow? How about how researchers in the past have constantly made up evidence of our "ancestors"? How about how the australopithecus can have its "evidence" attributed to a chimpanzee's skeleton? How about how dating is so inaccurate these days that if you give the same bone to different scientists, they date it with too staggering different dates? How about how their technique to date an object is about how deep it is in the ground yet how they know how old a layer is, is by which object is in there? Round-about, circular reasoning..
@@krinohs Well done mate, you literally said nothing. I know what science is as I study it. The amount of times someone thinks they have told me something new by telling me "what the word theory really means" is mind boggling. Your claim is that I am "vomiting" yet you didn't even really pay any attention to what I said. I picked apart all the major foundations of the evolution theory. I looked through your argument and couldn't find a single credible point! Why did you bother to reply?
@@krinohs David Firstly my names also David so we are namesakes! I think you have gotten mixed up. This is youtube's comment section not academia. But, alright. You claim I am using "Gish Gallop" another one of apparent logical fallacies which really is another way of ignoring someone. Really more about opinion than objective truth. I did not say a single thing that was untrue and if I said a "half-truth" it is more like things that are open to debate. Lets start with the fact that there has never been an example of new genetic material being added and only a strong phenotype of already existing genes, or modification of already existing genes. In examples of it, 100% of the time it is a medical illness. Also we see special organisms going extinct over time rather than the opposite.
@@krinohs To your comment about prayer, the truth is there is a good reason why I couldn't really be bothered to reply. You are really attacking me for nothing. If you believe my prayer is useless then there is nothing to squabble about since it doesn't really make any kind of difference. If your problem is about me not doing action then you can see the "work" in my name. If you think people who pray aren't statistically different to people who don't you'd be dead wrong. Just search it up. I have several anecdotal experiences and there are many records of people have been healed through prayer but you guys are ultra-skeptists to the point that you just claim any records whether electronic or simple eye witness is made up or the people are ignorant or extremely lucky. Do you really have a point different to what I begged?
The thing I have yet to see is a video that explains how we come to these particular visualisations of the microcosmic structures. That said. Nice upload very interesting. 👍
We have just learned breathing process in school today and it was explained absolutely unclear, there wasn't even said that the process takes place in mitochondria! But with that animation everything looks wery clear, despite the fact that english isn't my home language.
AH. That was amazing. This is a brilliant way to help students visualise. I also looovvee that narrators voice. This was extremely helpful. Thank you.!!!
It’s awesome that time was spent to make these animations and bring clarity to these processes. I think these videos need to be shown in grade school so that kids can be primed to learn how chemistry works later on in higher grades.
These kind of videos are quite valuable to me because they help me to get an idea on how different elements of nature work. In fact, the more I learn bits of science, the more I believe in Intelligent Design.
This is an awesome topic... very interesting. Especially if you are not into Darwinism and the amount of information going on at a molecular level...very impressive.
I learned about ATP, electron transport chain, and the citric acid cycle thirty years ago in a cell biology class. It was hard to visualize what was going on so I learned it by rote so I could spew it back out on a test. I envy students coming along now with these aids to understanding.
WHO WOULD DISKLIKE THIS? I actually love everyone who made this. It's so much different seeing something happen compared to reading a description in a textbook!
I have to say that I am in no way a biologist nor have experience or knowledge in biology (I only have the basics so I know what he is talking about), but seeing these proteins having these really complex operations, knowing that they emerged from only natural evolution is mind-blowingly amazing
I'm still amazed that all this complexity developed completely at random over a billion years of evolution from RNA in a lipid shell to full resperation. This stuff had to evolve early on in the very first cells or the cells couldn't have even survived. For instance, does anyone have any idea how the ATP synthase evolved into so complex a form? I don't believe in intelligent design or anything like that, but I still have problems wrapping my head around how a complete nano-turbine using single electrons as a power source simply built itself out of random atoms over time. I watch these videos of all these cell processes and the sheer complexity of it and it just boggles my mind.
Capitalist Radical man you contradict yourself . The hard question is how this tiny cell made this unbelievable protein "by luck"? But the hardest is how it made it in the form of a gene "DNA" that has no any kind of interaction with its protein And if we are looking for randomness where the other random genes in the bacteria that still has no function but will have one in the future by "evolution" It's all made by Allah not by luck ... We always say luck to keep our conscious from asking a lot of questions Wish you a good night without any anxious questions
Nick Lane has written a very good book about the workings of the mitochondria. There is a chapter in there on the origin of life; I quote from that chapter: " By injecting sodium sulphide solution (representing the hydrothermal fluid oozing from the bowels of the earth) into iron chloride solution (representing the early oceans) Russell and Hall produced a host of tiny, microscopic bubbles, bounded by iron-sulphide membranes. These bubbles have two remarkable traits... Firstly, the cells are naturally chemiosmotic ... [and] ... Secondly, the iron-sulphur crystals in the bubbly membranes conduct electrons (as indeed do the iron sulphide proteins that still exist on the mitochondrial membranes today)." Of course we're still awaiting a full explanation but scientists are getting closer all the time. The book is called Power, Sex, Suicide Mitochondria and the Meaning of Life. I don't much like the title myself but the book itself is excellent.
Mahmoud Ali John pritchard Two very strong replies. I still believe in God and also believe in evolution that happens because of God "Allah" as he "almighty God" said that he made a cause for everything and also that he didn't make anything without a reason or for amusement "it's actually hard for me to translate it"
Once the original code is set, it's designed for immortality and data collection: it's much more plausible that we're our own or another specie's tech. We code in two electromagnetic states. We're coded in four chemical states, so we're a ways off. But the similarities are too compelling to be discounted.
f. amazing. I am utterly flabbergasted at not only the way these chemical processes occur but how these brilliant scientists were able to determine it.
And to think this is just a small part of of of one of the 1000's of functions with in cell. The complexity of the just a few of the 30,000 different nanomachines and the amount of information ( communication) between them to create the required energy for the cell is truly astounding. It's no wonder that honest researchers acknowledge the complete failure or lack of Neo-Darwinian explanations to explain the thousands of sequential steps required for for the functioning of just one cell . Excellent video!
The laws of irreducible complexity are well shown here . How incredible and small and efficient . A good reflection of what a wonderful creator we have . The chance that this all happened by chance is mathematically impossible .
Holy F*ck, I have seen the future of education! Too bad it came 10 years too late for myself. Luckily for my students, I can share this masterpiece. Thanks, Omar Ali!
And you want to convince someone that educated person talks like this?! I doubt that a teacher has such poor vocabulary that has to use cussing. You talk like trash from the streets ,not like role model for the young
@@Horses4life1001 Dude, lighten up, it's just an expression to express amazement. I think we are a few generations apart, no? So I'd rather be 'closer' in a horizontal hierarchy to younger people who still need to learn than be stiff and condescending. Again, it's just an expression (and it's partly censored ;))
@@Horses4life1001 Teachers do indeed talk thuswise in this day and age. Communication is an important part of their occupation and it is best to attempt communicating in a language the other person is fluent in.
It is astounding that all of this was ascertained by scientists doing research into the workings of our Mitochondria. They were able to figure out the complexity of these interactions operating at a minute scale.
Wow. All the energy involved in ripping hydrogen atoms apart results in neutral water as its end result...I often wonder why "protonics" and the weak field is mot studied more...after all, the flagella rotor uses protons to fuel the worlds smallest and most powerful rotary engine. Protons have so much more energy than electrons. Yet, we still barely utilize the weak field, necessary to harness the protons....and our mitochondria do it on a molecular basis constantly with ease. A hydrogen atom stripped of its electron is a floating powerhouse proton that our cellular machinery just love. Just wow.
Well, I guess if half of the posters in this thread are to be believed, then we should maybe take it up with the "creator" for the next planned upgrade, let him know he could've done a better job.
Not sure what you mean by "protonics", but the ordinary word "chemistry" is used to describe reactions like the one here involving protons (also called hydrogen ions in this context) and it is extremely well studied. Also not sure what you mean by "the weak field". It sounds like you're possibly making some kind of reference to the weak force in particle physics, but that has nothing to do with what is going on here (and very little, in fact, to do with chemistry at all). The weak force is the force that mediates radioactive decay. There is no radioactive decay here. Chemistry works via the plain old electromagnetic force.
Wonderful and mind-blowing animation and demonstration of the electron transport chain and ATP synthase! Stumbled across this video while looking up information related to material covered in the book, "The Vital Question", (written by the biochemist, Dr. Nick Lane - a book I highly recommend to anyone interested in abiogenesis, i.e., the origin of life). Great animation!!
WuTang118 a prosthetic group is a permanent non protein component (cofactor) of a protein (FAD in this case). You can watch the FADH2 (reduced FAD) leave the complex II (succinate dehydroginase) in this video. This is the mistake.
Our God's design is truly amazing. Only out of pure and willful ignorance can anyone say this could evolve one small step at a time. I love these videos, just the facts, none of the 'millions of years' propaganda the evolutionist religion loves to shove down our collective throats. Love the video Omar.
Maybe if all of them were a pessimist like you. Humans have shown amazing development in scientific departement Remember when flying and going to outer space were a madman's random nonsense ? Yeah it already happened now and im sure in a few years we can make human ( or anything ) by constructing it quark - to quark Don't underestimate humans
@@sahibmujabee1177 humans have already been created so a higher more intelligent and supremely powerful being created humans first and everything else that is detectable and he, according to the latest scientific understanding, created it from that which is UNDETECTABLE. DON'T UNDERESTIMATE GOD.
@@gerardmoloney9979 from the latest research maybe but definitely not the final research and i never claim that humanity's science is at the utmost peak but we will difinitely get there as long as people who underestimate us dissapears
@@sahibmujabee1177 we must go where the evidence leads. That is true science. We know that information ONLY COMES FROM INTELLIGENT MIND. NO DOUBTS. TRUTH. DNA IS FULL OF INFORMATION CODE MORE COMPLEX THAN COMPUTER CODE. WHERE IS THAT FACT POINTING TO? TO THE MIND THAT INPUT THE INFORMATION, WHICH IS FAR MORE INTELLIGENT AND INFINITELY MORE POWERFUL THAN MAN, WHO SEEMS TO BE THE ONLY BEING CAPABLE OF UNDERSTANDING GODS EXISTENCE. WHERE IS THAT POINTING. GOD WANTS US TO HAVE A RELATIONSHIP WITH HIM. GOD IS THE ONLY ONE WHO CAN TELL THEM END FROM THE BEGINNING. THE OLD TESTAMENT PREDICTS THE NEW TESTAMENT. WHERE DOES THIS FACT POINT TO? TO THE GOD OF THE BIBLE. GOD BLESS YOU.
I mean that depends on how you define "close". Close as in within your lifetime? You might be right. Close as in the overwhelming majority of the time required to progress to a point where we can do that has already passed? You're dead wrong. We're at most a century from cracking this sort of molecular machinery, if not outright having a more or less complete understanding of genetics. Even just using the origin of science as a yardstick, science is already 500 years old, I would call 80% of the way there "close". Going back to the origin of society (where I would say humans truly achieved "modern" status) we're mere fractions of a percent from completion. We're probably close.
@Topics god is a cop out answer for things we do not know, that somehow manages to create more questions than answers. Please stop presupposing that your specific god (or general god) created everything, the world would be better off with people that actually think critically and follow the evidence. if no evidence is provided, that is enough to simply dismiss a claim such as your god.
This is powerful evidence we were designed. There is no other reasonable conclusion. Any one that would believe otherwise is not being honest with themselves.
@@mwils51 yet this is only a single part of the uncountable processes that makes life possible. The Bible clearly states that the creation is evidence of the creator and I think its pretty obvious
@@electric_photon4660 the fact that you are not able to comprehend that with the amount of time that has passed and the size of the universe that things like this happen shouldn't prove creation, count the stars in the sky, and the number of years that have passed and you will realise that everything can happen if you happen with the grand size of the universe and the incomprehensible time that has passed.
And all this by chance and with out a purpose. What a marvelous things the sense-less, mind less, goal less Big bang has created!! An everything for the glory of no one.
It is so wierd that inside a Cell, basically in the Center of Life itself, there is no Life at all! Inside the Cell nothing is alive, there is just highly complex Chemistry and Physics.... Every Time I think about this Paradoxon my Head starts to 🤯
@@nofurtherwest3474 that is just your point of view since you are assuming that intelligence or perception is not everywhere in nature. you assume physics is completely separate from what we call "mind" however this is a philosophical belief system ie materialism and in no way proven
jooky87 , yes indeed. The normal isotope of the hydrogen atom consists of one proton and one electron. When the electron is missing for some reason, we’ve got just the proton which in turn lowers the pH (medium is getting sour
1:50 it's a watermill. 3:00 electricity powered hydro pumps to feed the watermill. This is just insane. And people say its all an "accident by trial and error". And people say "why would alien life be interested in us, we're so primitive?" For gods sake just look at what's going on within us, if all alien life is independently evolved using different mechanisms, every single planet is utterly breathtakingly interesting just for how the microcosm within living entities work on that particular planet. Imagining finding another planet with a civilization of sentient beings. Now imagine doing THIS kind of microbiology on THEM. You'd be spending hundreds of years and still not figure out how everything works. We barely know how WE work.
7:11 -Narrator: "this makes the surface of the inner mytrocondrial memabrane a gigant celular..." -Me: *"POWERHOUSE"* -Narrator: "...powerplant" -Me: *SHAME*
also You can watch Videos related to Mitochondria and Electron Transport Chain (ETC)
1-ATP Synthase Structure:
ruclips.net/video/WzqVu8OWedo/видео.html
2-ATP Synthase Mechanism:
ruclips.net/video/39UKSfsc9Z0/видео.html
3-ATP Synthase in Action:
ruclips.net/video/A2my52zQA6k/видео.html
4-Glycolysis
ruclips.net/video/KfWkZZZjMQE/видео.html
5-Citric Acid Cycle (TCA)
ruclips.net/video/82CplqKfw90/видео.html
Omar, what powers the rotation motion? 1:15
i think the gradient of H ions will power it, because a gradient stores energy (which is also used to transport against gradient as well as along gradient in case of many transporters, e.g as occurs in the secondary type of active transport ^.^ ) im not 100% sure tho, im just thinking :P
@@goosecouple the concentration gradient between the matrix and the intermembrane space forces the protons to enter from the intermembrane space to the matrix through the F1F0 ATP Synthase which makes ATP molecules from ADP and inorganic phosphate "Pi" molecules
@@goosecouple the concentration gradient is the presence of more protons on one side of the membrane than the other side
The Body's Gas Station
The fact that this is occurring inside me right now on an incomprehensibly massive scale leaves me in awe...
borderline disturbing
wow
And that humans have figured this out in such detail.
judaspreistvlct the fact that it came about from the laws of nature and eons of time, makes it exquisite.
Erick Lee and the laws of nature came from? The absurdity of the infinite redux is sure to come up soon.
@Jay Blake A simpler or more efficient process may exist but it may also be too slow to compete with this complex process.
There used to be a simple version of blood but it couldn't support animals thicker than a worm so complex blood with iron was favoured by evolution.
I've heard all my life that mitochondria are power cells, but never understood any explanation using a book at school, this is mind blowing for me, it all makes sense now.
yes..i wanna say as it is your words....but u already said....
Someone doesn't pay attention at class
You're likely lying. Textbooks do an excellent job, if not medical textbooks do the job. This video is nice, but nothing beats actual, sanctioned education.
Absolutely agree. Mind blown.
Everything beats sanctioned education, unless you enjoy slavery
These animations are so much better than dry words alone on a page . Not everyone is good at mental visualization from a written description. I'm a visual learner and seeing things like this help immensely.
Maybe a clue for new types of battery?🎉🎉
He failed completely to explain the real actual chemical reactions therefore this is pure garbage. You could be watching pokemon to the same value.
@@Mindsi you must be rxextxaxrxdxexd.
@@MindsiDamn who hurt you, chill tf out
I cannot believe what I'm looking at. Imagine the people hundreds of years ago making water wheels and windmills had no idea they were copying the micro-machines that make the body run. Incredible!
Ôi mê ly! 🤩💯
this is the BEST ANIMATION TO EXPLAIN CELULAR RESPIRATION thanks
Eduardo Guths its made by biovisions
It’s immensely pulchritudinous
@@rashoietolan3047 I can do it in three syllables...
This visualization seriously is empowering. Taking otherwise abstract thoughts and making them coherent and digestible, and not only that but actually cool and engaging! Jeez, man.. Everyone who was involved in creating and distributing this lesson, thank you thank you thank!!
I don't know how to help you if this doesn't make you awe inspired. This is going on in your body _right now_ and is the reason you could even watch and remember it. This is beautiful. Thank you for posting.
lol the type of guy
This is possibly the best explanation for anything, ever. This is how you educate.
Excellent! I wish I had had these animations available when I was taking my Biochemistry courses. It would have made things SO much easier! Thank you for the effort you put into these remarkable videos.
BB
They had just published DNA's helical form when I first studied biology. The beauty of the molecular level of life is mindblowing.
10 điểm 💥✨
Proteins are so flipping amazing. I look forward to the day that we can accurately predict and control protein folding. Imagine that; the ability to create a molecule to catalyze any reaction we could possibly think of. I'm thinking the ability to take CO2 out of the air and very efficiently turn it into plastics or fuels, or the ability to easily turn large quantities of CO2 into O2 for interplanetary travel, then the ability to directly synthesize sugars and foods from the Carbon produced. The ability to manufacture more efficient solar panels. Perfectly efficient recycling of waste materials. Factories that produce no pollutants. Mass production of graphene or carbon nanotubes. The ability to cure any diseases and possibly solve aging. The possibilities are endless!
The future is at our fingertips. Its amazing how the politics and economics of controlling ppl has completely stiffled these possible advancements that you spoke of.
hydroxyl absorption of GOLD Au as discussed in the musfut or shumanna. less than zeropoint.
imagine we create unicorns
the ability to fuck up and in one fell swoop, wipe all life off the face of the earth, get real man, if we try to play God, we will get whipped hard.
This is the best video I've ever seen on RUclips. Seriously. This is what I always hoped the internet would look like... but it didn't.
Also, it's pretty funny that you use the word "giant" at the end to describe a mitochondrion. Everything is relative, I guess.
Watch some of the dna videos
Yeah i didnt know content like this even existed until yesterday and there's actual footage of other small systems here on yt by Science Insider : Award Winning Footage Of The Microscopic World Around Us aaaand Drew Berry: Animations of unseeable biology
That moment when you realize that physics and chemistry and biology really are all the same thing.
Sort of. Physics is the 'fundamental' science from which all others are derived. At the most basic level we are ginormous collections of quarks and leptons.
@@wntu4 They're all just varying levels of abstraction from fundamental physics.
@@wntu4 At the most basic we are made of vibrations
They're all math.
@@eyescreamcake yes ppl fail to realise this I would site- "math is perhaps the only reliable science we have"-jayahsankara -ancient indian mathematician the statement is pretty powerful as the patterns in maths r the patterns of cosmos
This is a blessing because the only way I seem to absorb information is if I can see exactly what is being described. Thank you for your skills and information!
I am the same
That was incredible, I can't believe how utterly complicated life is.
Great animations. I'll be using this video with my students. Thanks!
What I have read and reviewed from several chapters of Stephen White's Physiology and Biochemistry of Prokaryotes for several days have been summarized comprehensively in an 8 minute video. Saying that this video is amazing is clearly an understatement!!! 👏🏼👏🏼👏🏼
I feel like I’m looking at our source code
You are.
Little by little, day by day we're unraveling exactly that.
There's a lot of bugs.
@@rsrt6910 It takes a long time to understand because it's written in C.
@@SoulGnosis You are not
The animation and narration made the electron transport chain seem "real" and very understandable. the world is surely better off because of this video. thank you for making it.
I feel so grateful to you, guys! I don't want to imagine how much work it takes to create such a beautiful and informative clip like this! Amazing job!
The word of “Amazing" gains a meaning itself in this process here
WOW. One of the best atomic-animations I have seen in a while. Very impressed
This is like some kind or revolution in the teaching of science. This is cutting edge stuff. And it's being made very accessible to the general public. If I didn't see it I wouldn't believe it.
Totally astounds me finding that Protons are freely traveling without neutrons and electrons in living matter. These reactions are so complex, they could have never come about by blind chance - this is an amazing part of a cleverly designed factory
This was the coolest science video I’ve ever seen well done
finally understand what they call it the powerhouse of the cell! :)
It took 11 comments sorted by popularity to find one mention of *"the powerhouse."*
This makes me sad.
More like an energy processer....
This is the kind of show I'd watch. This is absolutely magnificent. I've been struggling to visualize the entire thing, this makes it so easy.
This is hands down the best explanation I've seen yet.
I had no idea how these processes actually occurred naturally inside our cells. Truly amazing to a layman like myself. Thank you for the uploads
This is better than any college slideshow
I know in detail how this stuff works but never tire of marvelling at it. It bloody maraculous 👍
Thank you to all the energy spent by those great minds that contributed/ing towards putting together this incredible puzzle. And of course to the people for this awesome presentation.
Wow, I'm at a loss for words! I simply can not comprehend topics like this by just reading a textbook. Animations, however, ellucidate topics and enhances the learning process. Thank you for posting this video.
Where has this animation been all my life? If only we had these back when I was taking biology and biochemistry classes.
In contrast to what the video shows, FAD is not a soluble electron carrier but rather is covalently bound to complex II (succinate dehydrogenase). It is succinate (from the Citric Acid Cycle) that delivers electrons to the complex.
exactly
and you can see more details about Citric Acid Cycle in here
ruclips.net/video/82CplqKfw90/видео.html
It`s a mistake in the video
@@3omarali Thank you for being willing to admit mistakes! I've argued till blue in the face with some people who have made simple, minor errors in education videos and can't bring themselves to just admit it and fix it.
I don't care how beginner understanding the electron transport chain is. I'm watching (and understanding) a Harvard video, this is as close to a formal education as i have ever come!
The Universe deserves props for every inconceivably tiny structure that operates as a factory.
Nah creation doesn't get credit. Creator does.
@@krinohs David When did I say natural process doesn't occur?
If you mean to say evolution? I am not buying it. There is no example of species gaining a new gene, only examples of losing old features or modifying old features with already existing features.
There is more proof that it is more like old animals are dying over time than new animals appearing. Each day we see more and more species going extinct.
If you know anything about carbon dating, you would know it is getting irrelevant because fossils we are interested in are "too old". It should be impossible for us to find traces of carbon-14 right?
Well how about us finding dinosaur flesh and bone marrow?
How about how researchers in the past have constantly made up evidence of our "ancestors"? How about how the australopithecus can have its "evidence" attributed to a chimpanzee's skeleton?
How about how dating is so inaccurate these days that if you give the same bone to different scientists, they date it with too staggering different dates?
How about how their technique to date an object is about how deep it is in the ground yet how they know how old a layer is, is by which object is in there? Round-about, circular reasoning..
@@krinohs Well done mate, you literally said nothing. I know what science is as I study it. The amount of times someone thinks they have told me something new by telling me "what the word theory really means" is mind boggling. Your claim is that I am "vomiting" yet you didn't even really pay any attention to what I said. I picked apart all the major foundations of the evolution theory.
I looked through your argument and couldn't find a single credible point! Why did you bother to reply?
@@krinohs David Firstly my names also David so we are namesakes! I think you have gotten mixed up. This is youtube's comment section not academia. But, alright.
You claim I am using "Gish Gallop" another one of apparent logical fallacies which really is another way of ignoring someone. Really more about opinion than objective truth. I did not say a single thing that was untrue and if I said a "half-truth" it is more like things that are open to debate.
Lets start with the fact that there has never been an example of new genetic material being added and only a strong phenotype of already existing genes, or modification of already existing genes. In examples of it, 100% of the time it is a medical illness. Also we see special organisms going extinct over time rather than the opposite.
@@krinohs To your comment about prayer, the truth is there is a good reason why I couldn't really be bothered to reply. You are really attacking me for nothing. If you believe my prayer is useless then there is nothing to squabble about since it doesn't really make any kind of difference. If your problem is about me not doing action then you can see the "work" in my name.
If you think people who pray aren't statistically different to people who don't you'd be dead wrong. Just search it up.
I have several anecdotal experiences and there are many records of people have been healed through prayer but you guys are ultra-skeptists to the point that you just claim any records whether electronic or simple eye witness is made up or the people are ignorant or extremely lucky.
Do you really have a point different to what I begged?
The level of detail added in these animation makes it more interesting and therefore easier to learn.
The thing I have yet to see is a video that explains how we come to these particular visualisations of the microcosmic structures.
That said.
Nice upload very interesting. 👍
It's all algorithms. Google "visualization protein modeling"
suzbone algorithmes!?! They came how?
There are merely human-made 3D animations. There is no tech available to visualize the reality they represent.
We have just learned breathing process in school today and it was explained absolutely unclear, there wasn't even said that the process takes place in mitochondria! But with that animation everything looks wery clear, despite the fact that english isn't my home language.
AH. That was amazing. This is a brilliant way to help students visualise. I also looovvee that narrators voice. This was extremely helpful. Thank you.!!!
It's amazing to me how intricately, and beautifully God designed us. Great video
Incredible how we imitate our own physically visible lives very similarly to how we are made..great vid
I love the name of this channel. Gives me peace
I wish i've seen this video before my final exam :3 however it's always a pleasure to understand even a small glimpse of great biology !!
It’s awesome that time was spent to make these animations and bring clarity to these processes. I think these videos need to be shown in grade school so that kids can be primed to learn how chemistry works later on in higher grades.
These kind of videos are quite valuable to me because they help me to get an idea on how different elements of nature work. In fact, the more I learn bits of science, the more I believe in Intelligent Design.
Please keep making videos like this Omar, don’t quit.
This is amazing!!! Fantastic work
The Moment we watch These in University to understand the process. Thank u , helfen me a lot!
I’m going for engineering but man I respect all you bio majors and medical people. This stuff is not easy! I feel like I have it easy. Good luck.
I don’t speak English but mec wallah t’es incroyable tu m’a sauvé
I don't know how to thank you for making this horrible topic easier for me
its only horrible if you make it so
@Dip Patel or if your teacher make it so :D
Omar Ali very true
This is an awesome topic... very interesting. Especially if you are not into Darwinism and the amount of information going on at a molecular level...very impressive.
@@3omarali No, teachers aren't to blame for whiny students.
I learned about ATP, electron transport chain, and the citric acid cycle thirty years ago in a cell biology class. It was hard to visualize what was going on so I learned it by rote so I could spew it back out on a test. I envy students coming along now with these aids to understanding.
One of the best videos i've ever seen. Thanks, good sir!
I just rewatched this video again - gosh it's fantastic. I had forgotten about how wonderful it is..
I cannot express my feeling
It is wonderful
WHO WOULD DISKLIKE THIS?
I actually love everyone who made this. It's so much different seeing something happen compared to reading a description in a textbook!
I learned about this in high school, but at the time we had no idea HOW the pumps worked, this is interesting to me for that reason.
I have to say that I am in no way a biologist nor have experience or knowledge in biology (I only have the basics so I know what he is talking about), but seeing these proteins having these really complex operations, knowing that they emerged from only natural evolution is mind-blowingly amazing
I'm still amazed that all this complexity developed completely at random over a billion years of evolution from RNA in a lipid shell to full resperation. This stuff had to evolve early on in the very first cells or the cells couldn't have even survived. For instance, does anyone have any idea how the ATP synthase evolved into so complex a form? I don't believe in intelligent design or anything like that, but I still have problems wrapping my head around how a complete nano-turbine using single electrons as a power source simply built itself out of random atoms over time. I watch these videos of all these cell processes and the sheer complexity of it and it just boggles my mind.
Capitalist Radical man you contradict yourself .
The hard question is how this tiny cell made this unbelievable protein "by luck"?
But the hardest is how it made it in the form of a gene "DNA" that has no any kind of interaction with its protein
And if we are looking for randomness where the other random genes in the bacteria that still has no function but will have one in the future by "evolution"
It's all made by Allah not by luck ... We always say luck to keep our conscious from asking a lot of questions
Wish you a good night without any anxious questions
Nick Lane has written a very good book about the workings of the mitochondria. There is a chapter in there on the origin of life; I quote from that chapter: " By injecting sodium sulphide solution (representing the hydrothermal fluid oozing from the bowels of the earth) into iron chloride solution (representing the early oceans) Russell and Hall produced a host of tiny, microscopic bubbles, bounded by iron-sulphide membranes. These bubbles have two remarkable traits... Firstly, the cells are naturally chemiosmotic ... [and] ... Secondly, the iron-sulphur crystals in the bubbly membranes conduct electrons (as indeed do the iron sulphide proteins that still exist on the mitochondrial membranes today)." Of course we're still awaiting a full explanation but scientists are getting closer all the time. The book is called Power, Sex, Suicide Mitochondria and the Meaning of Life. I don't much like the title myself but the book itself is excellent.
I'll have to pick that up. That paragraph alone is pretty enlightening, let alone the entire book. Thanks
Mahmoud Ali John pritchard
Two very strong replies.
I still believe in God and also believe in evolution that happens because of God "Allah" as he "almighty God" said that he made a cause for everything and also that he didn't make anything without a reason or for amusement "it's actually hard for me to translate it"
Once the original code is set, it's designed for immortality and data collection: it's much more plausible that we're our own or another specie's tech. We code in two electromagnetic states. We're coded in four chemical states, so we're a ways off. But the similarities are too compelling to be discounted.
f. amazing. I am utterly flabbergasted at not only the way these chemical processes occur but how these brilliant scientists were able to determine it.
And to think this is just a small part of of of one of the 1000's of functions with in cell.
The complexity of the just a few of the 30,000 different nanomachines and the amount of
information ( communication) between them to create the required energy for the cell
is truly astounding. It's no wonder that honest researchers acknowledge the complete
failure or lack of Neo-Darwinian explanations to explain the thousands of sequential steps
required for for the functioning of just one cell .
Excellent video!
Nanomachines son.
Best Channel to learn Biology 🌏...☺️☺️☺️☺️☺️
The laws of irreducible complexity are well shown here . How incredible and small and efficient . A good reflection of what a wonderful creator we have . The chance that this all happened by chance is mathematically impossible .
Thanks for putting this together, wonderful graphics and great commentary.
Holy F*ck, I have seen the future of education! Too bad it came 10 years too late for myself. Luckily for my students, I can share this masterpiece. Thanks, Omar Ali!
And you want to convince someone that educated person talks like this?! I doubt that a teacher has such poor vocabulary that has to use cussing. You talk like trash from the streets ,not like role model for the young
@@Horses4life1001 Dude, lighten up, it's just an expression to express amazement. I think we are a few generations apart, no? So I'd rather be 'closer' in a horizontal hierarchy to younger people who still need to learn than be stiff and condescending. Again, it's just an expression (and it's partly censored ;))
@@Horses4life1001 Teachers do indeed talk thuswise in this day and age. Communication is an important part of their occupation and it is best to attempt communicating in a language the other person is fluent in.
@@Biomeducated I would not like you to be to "close" to my kids. I hope you are not their teacher
@@Biomeducated You not going to convince me that cursing teacher is good for MY kids. Get lost
BRAVO ! Excellent, informative and educative video, perfecter my students. Thank you from Italy
That’s the most amazing thing I ever saw
It is astounding that all of this was ascertained by scientists doing research into the workings of our Mitochondria. They were able to figure out the complexity of these interactions operating at a minute scale.
And some say this happened by accident. Clearly this is by design. Simply AMAZING!
no
Wow, I finally got understand how the Electron Transport Chain works. This answers a lot of questions that are not fully explained on the book.
Wow. All the energy involved in ripping hydrogen atoms apart results in neutral water as its end result...I often wonder why "protonics" and the weak field is mot studied more...after all, the flagella rotor uses protons to fuel the worlds smallest and most powerful rotary engine. Protons have so much more energy than electrons. Yet, we still barely utilize the weak field, necessary to harness the protons....and our mitochondria do it on a molecular basis constantly with ease. A hydrogen atom stripped of its electron is a floating powerhouse proton that our cellular machinery just love. Just wow.
Well, I guess if half of the posters in this thread are to be believed, then we should maybe take it up with the "creator" for the next planned upgrade, let him know he could've done a better job.
Not sure what you mean by "protonics", but the ordinary word "chemistry" is used to describe reactions like the one here involving protons (also called hydrogen ions in this context) and it is extremely well studied.
Also not sure what you mean by "the weak field". It sounds like you're possibly making some kind of reference to the weak force in particle physics, but that has nothing to do with what is going on here (and very little, in fact, to do with chemistry at all). The weak force is the force that mediates radioactive decay. There is no radioactive decay here. Chemistry works via the plain old electromagnetic force.
Thanks for that last disclaimer. That's the sort of thing that leaves me totally confused when it often goes unexplained.
Wonderful and mind-blowing animation and demonstration of the electron transport chain and ATP synthase! Stumbled across this video while looking up information related to material covered in the book, "The Vital Question", (written by the biochemist, Dr. Nick Lane - a book I highly recommend to anyone interested in abiogenesis, i.e., the origin of life). Great animation!!
I am at loss of words for how amazing these videos are.
FADH2 is a prosthetic group of complex II and does not leave the enzyme once oxidized. Otherwise realy good animation
wow
I know this information well but this is the first time for me to notice this mistake in the video
thanks for note.
you are welcome :)
what do you mean its a prosthetic group of ocmplex 2?
WuTang118 a prosthetic group is a permanent non protein component (cofactor) of a protein (FAD in this case). You can watch the FADH2 (reduced FAD) leave the complex II (succinate dehydroginase) in this video. This is the mistake.
Thanks
Very complex process with protein complexes explained to make it less complex - Very helpful!
Our God's design is truly amazing. Only out of pure and willful ignorance can anyone say this could evolve one small step at a time. I love these videos, just the facts, none of the 'millions of years' propaganda the evolutionist religion loves to shove down our collective throats. Love the video Omar.
Then you probably shouldn't have masturbated your religion all over the comments section.
great video, thank you! pure information in proper pace instead of narrator self-promotion like majority of other ones do.. pure gold! (y)
This is nanotechnology that humans are nowhere close to building.
Maybe if all of them were a pessimist like you. Humans have shown amazing development in scientific departement
Remember when flying and going to outer space were a madman's random nonsense ? Yeah it already happened now and im sure in a few years we can make human ( or anything ) by constructing it quark - to quark
Don't underestimate humans
@@sahibmujabee1177 humans have already been created so a higher more intelligent and supremely powerful being created humans first and everything else that is detectable and he, according to the latest scientific understanding, created it from that which is UNDETECTABLE. DON'T UNDERESTIMATE GOD.
@@gerardmoloney9979 from the latest research maybe but definitely not the final research and i never claim that humanity's science is at the utmost peak but we will difinitely get there as long as people who underestimate us dissapears
@@sahibmujabee1177 we must go where the evidence leads. That is true science. We know that information ONLY COMES FROM INTELLIGENT MIND. NO DOUBTS. TRUTH. DNA IS FULL OF INFORMATION CODE MORE COMPLEX THAN COMPUTER CODE. WHERE IS THAT FACT POINTING TO? TO THE MIND THAT INPUT THE INFORMATION, WHICH IS FAR MORE INTELLIGENT AND INFINITELY MORE POWERFUL THAN MAN, WHO SEEMS TO BE THE ONLY BEING CAPABLE OF UNDERSTANDING GODS EXISTENCE. WHERE IS THAT POINTING. GOD WANTS US TO HAVE A RELATIONSHIP WITH HIM. GOD IS THE ONLY ONE WHO CAN TELL THEM END FROM THE BEGINNING. THE OLD TESTAMENT PREDICTS THE NEW TESTAMENT. WHERE DOES THIS FACT POINT TO? TO THE GOD OF THE BIBLE. GOD BLESS YOU.
I mean that depends on how you define "close". Close as in within your lifetime? You might be right. Close as in the overwhelming majority of the time required to progress to a point where we can do that has already passed? You're dead wrong. We're at most a century from cracking this sort of molecular machinery, if not outright having a more or less complete understanding of genetics. Even just using the origin of science as a yardstick, science is already 500 years old, I would call 80% of the way there "close". Going back to the origin of society (where I would say humans truly achieved "modern" status) we're mere fractions of a percent from completion.
We're probably close.
Holy Crap... Cellular power generation at the smallest level. Never thought I'd see us progress to this level of understanding. Amazing.
It's fantastic how far science has gotten. And how far evolution has gotten! That's some fantastic machinery.
Machines don't create themselves. It needs a designer.
@@categories5066
Not necessarily.
@@rsrt6910. Name me one machine where it did not need a designer
@@categories5066
The Electron Transport Chain (to start with).
@Topics god is a cop out answer for things we do not know, that somehow manages to create more questions than answers.
Please stop presupposing that your specific god (or general god) created everything, the world would be better off with people that actually think critically and follow the evidence. if no evidence is provided, that is enough to simply dismiss a claim such as your god.
Damn, I wish we'd had this back when I was studying biochemistry in the Stone Age.
I cant imagine how people can see and understand this and believe that it just evolved by random chance
This is powerful evidence we were designed. There is no other reasonable conclusion. Any one that would believe otherwise is not being honest with themselves.
@@mwils51 yet this is only a single part of the uncountable processes that makes life possible. The Bible clearly states that the creation is evidence of the creator and I think its pretty obvious
@@electric_photon4660 the fact that you are not able to comprehend that with the amount of time that has passed and the size of the universe that things like this happen shouldn't prove creation, count the stars in the sky, and the number of years that have passed and you will realise that everything can happen if you happen with the grand size of the universe and the incomprehensible time that has passed.
Mike Wilson this is definitely not evidence for a “designer”. This alone isn’t evidence for evolution either.
I mean, wow! This helped inspire a new passion for cellular biology in me. Great video!
Thank you for this great animation!
And all this by chance and with out a purpose. What a marvelous things the sense-less, mind less, goal less Big bang has created!!
An everything for the glory of no one.
Mind boggling stuff, how can you work out what is happening a such a microscopic level ? Very interesting video
He didn't...he's just explained what he has learned.
CRYIPTIC CREEP learned from who and who was first to know?
@@jean-marclamothe8859 Your Decision Matters
@@jean-marclamothe8859 From biology education system perhaps?
As for the first to know, there are encyclopedias and Pubmed for that.
After all these yrs. I finally know HOW and WHY mitochondria is the power house of the cell.
It is so wierd that inside a Cell, basically in the Center of Life itself, there is no Life at all! Inside the Cell nothing is alive, there is just highly complex Chemistry and Physics.... Every Time I think about this Paradoxon my Head starts to 🤯
Yes at the smallest levels it is all physics. It is miraculous and fascinating stuff.
@@nofurtherwest3474 that is just your point of view since you are assuming that intelligence or perception is not everywhere in nature. you assume physics is completely separate from what we call "mind" however this is a philosophical belief system ie materialism and in no way proven
@@soldatheero you lost me bro, i am not smart enough to understand
I love astronomy, but I find it more astonishing that we are able to describe those infra process.... Thanks you, science !
Wait, by protons do we mean hydrogen ions?
jooky87 , yes indeed. The normal isotope of the hydrogen atom consists of one proton and one electron. When the electron is missing for some reason, we’ve got just the proton which in turn lowers the pH (medium is getting sour
The term was general and I guess it refers to any atom or compound with a positive charge (or an electron missing)
@@RandomNullpointer No, in the electron transport chain it's literally protons (H+ ions).
jooky87 yes. Any random individual proton is technically a hydrogen ion which I think is pretty funny.
no ,
I had no idea our bodies use individual atom components like electrons and protons. What a complex procedure. Like I'm awe struck
1:50 it's a watermill. 3:00 electricity powered hydro pumps to feed the watermill.
This is just insane. And people say its all an "accident by trial and error".
And people say "why would alien life be interested in us, we're so primitive?"
For gods sake just look at what's going on within us, if all alien life is independently evolved using different mechanisms, every single planet is utterly breathtakingly interesting just for how the microcosm within living entities work on that particular planet.
Imagining finding another planet with a civilization of sentient beings. Now imagine doing THIS kind of microbiology on THEM.
You'd be spending hundreds of years and still not figure out how everything works. We barely know how WE work.
"This is just insane. And people say its all an "accident by trial and error"." Indeed 0+0 Can never equal 1
@@calmguy.4659 And yet it did, and here it is!
Absolutely fantastic. The animation makes it so much easier to understand.
7:11
-Narrator: "this makes the surface of the inner mytrocondrial memabrane a gigant celular..."
-Me: *"POWERHOUSE"*
-Narrator: "...powerplant"
-Me: *SHAME*
Look at those Van-der-waal interacts, haha! Great video, btw. really helped me visualize what all my biochem lectures were describing!
MITOCHONDRIA IS THE POWERHOUSE OF THE CELL
thanks for this incredible animation. broken down explicitly