Metabolism | Mobilization of Triglycerides

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  • Опубликовано: 7 сен 2024
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    In this lecture Professor Zach Murphy will present on the mobilization of triglycerides, and go into more detail on the process of triglyceride synthesis. We hope you enjoy this lecture and be sure to support us below!
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    #ninjanerd #TriglycerideMobilization #Metabolism

Комментарии • 272

  • @RA-ru1rd
    @RA-ru1rd 4 года назад +279

    I’m Russian and I’m studying in Russian university on Russian language, English is my foreign language, but I understand your videos more better than Russian books and videos about biochemistry. Thank you very much!

    • @besoyeb2714
      @besoyeb2714 3 года назад +5

      ахуенно братуха жиза

    • @sajagraf2092
      @sajagraf2092 2 года назад +6

      Me too , and I’m libyan , I understand him more than our university doctors 🥲🫶🏻.

    • @lyliaguennache4587
      @lyliaguennache4587 2 года назад +7

      Me too , i'm Algerian and i'm studying in french but i understand his videos more better than my french books🤦‍♀️
      Ps: french is our second language and english is the 3rd one 🙂

    • @winnifredadong9342
      @winnifredadong9342 2 года назад +3

      Am me am from Uganda we used English but he's far much better than our lecturer

    • @mamdohyounis4308
      @mamdohyounis4308 Год назад +10

      @@sajagraf2092 I am actually an ALien from Korach lisek planet and i undestand him more than our planets professors even though we have no liver nor do we have blood system

  • @cfazmin9319
    @cfazmin9319 2 года назад +85

    For me Biochemistry is one of the difficult ones to get in touch. After watching these videos it seems like biochem is one of the easiest subject study. This professor is really dedicated to this work. This teaching method is extremely effective. I've felt like I am being in a real live lecture. There are lots of Science related videos out there. But "Ninja Nerd" videos really valuable to share with others. Keep it up Sir.
    God bless you.

    • @okodioscar7518
      @okodioscar7518 2 года назад +2

      Indeed this guy is gifted in teaching science. I love him so much

  • @SefraCorrea
    @SefraCorrea 4 года назад +23

    Your explanation is great and your videos have been very helpful to me

  • @robinkabous9651
    @robinkabous9651 5 лет назад +25

    Love that you summarize everything at the end so you understand how everything connects

  • @kellysoares3001
    @kellysoares3001 2 года назад +8

    You know you're getting absolutely nothing from your uni classes when you're able to understand the subjects better when you're watching RUclips videos in a foreign language... Thank you so much for this! :D

  • @isharaj6499
    @isharaj6499 4 года назад +12

    OMG this is when I realized that metabolism is not a hard unit. But you just gotta understand whats happening. Thank you so much for this video. It really helped me to understand as a visual learner.

  • @risaalmeida1785
    @risaalmeida1785 9 месяцев назад +5

    literally makes this entire material 100000000 more understandable!

  • @blessedwithbread9443
    @blessedwithbread9443 7 лет назад +71

    Amazing Stuff... Really appreciate the hard work. For specific topics this is better than Khan academy.

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  7 лет назад +18

      +Blessed with Bread wow! Thank you for your kind words they mean so much. I hope these videos helped.

    • @taukirhamja5711
      @taukirhamja5711 4 года назад +9

      @@NinjaNerdOfficial I like this guy for serving the medical lectures free. i have no credit card to help this chennel as patron.but i click more ads when i watch lectures. I think that ninja nerd also can start a website for the test of every video such as the MCQ test for free. It also helps us to understand the topic more.

    • @mdimrannoor4765
      @mdimrannoor4765 2 года назад +1

      @@taukirhamja5711 For someone without any credit card, you’re asking too much. Beggars don’t get to choose.

  • @umerbinshabir6561
    @umerbinshabir6561 5 лет назад +21

    High quality time saving lec

  • @user-bc1rr2lu6e
    @user-bc1rr2lu6e 2 года назад

    I could not find info on "the movilization of triglycerides". Here you are again Ninja to the rescue!!

  • @priyalmudgal1863
    @priyalmudgal1863 2 года назад +3

    Sir, your manner of explanation and your concepts were impeccable, thank you so much for helping out students this way.

  • @CarrieHonigman
    @CarrieHonigman 2 года назад +2

    Beautiful! Such a clear explanation of mobilization of triglycerides. Thank you.

  • @raghadalomari4058
    @raghadalomari4058 6 лет назад +29

    gluco-GONE :D
    Thank you for the simple yet great explanation :)

    • @thefenerbahcesk4156
      @thefenerbahcesk4156 5 лет назад

      Doesn't glucagon do the opposite though? It releases glucose?

    • @azkaqaiser1691
      @azkaqaiser1691 3 года назад

      @@thefenerbahcesk4156 it's released when blood glucose is low

  • @winnifredadong9342
    @winnifredadong9342 2 года назад

    This video has saved many students throughout the whole world whenever I watch video of Ninja Nerd I understand biochemistry to the fullest capacity Thankyou so much May God bless you abundantly

  • @svetlanavrach5159
    @svetlanavrach5159 6 лет назад +30

    This video is just amazing ! You explained it such a simple way! I really thank you from the bottom of my heart for saving my life ! It would have been too boring to study Biochemistery from my teacher's lesson. Thank you ! You do a great job ! (I'm medical student ;) So u're saving my life and the ones of people I will meet during my career) -Sorry If my english is not that good ... I speak french and german, not english-

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад +8

      +Svetlana Vrach thank you so much for your super kind words we really appreciate that best of luck in your future endeavors.

  • @AkbarAli-ud7sy
    @AkbarAli-ud7sy 2 года назад +1

    Can't thank this channel enough for providing such relevant and conceptually clear content for medical school.

  • @illumizoldyck8038
    @illumizoldyck8038 3 месяца назад

    That ester bond look gooood
    Is now living rent free in my head

  • @yangwish320
    @yangwish320 Год назад +1

    My exam on monday in biochemistry will be saved because of you :D My Lehninger book is way too complicated to read. Thank you!

  • @learnwithareesha458
    @learnwithareesha458 3 года назад +1

    Your videos are always helping me grasp biochemistry concepts easily. Thanks Zac.

  • @16-awaabkhan42
    @16-awaabkhan42 4 года назад +2

    MHM .....THAT ESTER BOND LOOK GOOOOOODD !

  • @jimfitzgerald6510
    @jimfitzgerald6510 Год назад

    Since 1975 I've sat in or participated in untold number of medical presentations. That was a thing of beauty.

  • @dralily7894
    @dralily7894 4 года назад

    I didn't understand it from the university professor, but a ninja always makes everything easy.
    Thank you very much.
    We love you and appreciate your hard work
    from the state of Libya in North Africa ^^

  • @Abdou-qt3wq
    @Abdou-qt3wq Месяц назад

    you're truly a hero for students

  • @therealdreshady
    @therealdreshady Год назад

    hey guys at ninja nerd. i want to start off by saying i love your videos, theyre great, but i wanted to point out, for TAG the first hydrolysis is done by HSL, DAG then gets hydrolyzed by LPL, then the last one is MAG lipase.

  • @visible-lp2sf
    @visible-lp2sf 4 месяца назад

    Lectures are ultimate. Thanks for providing educational videos.

  • @harristahir9193
    @harristahir9193 6 лет назад +2

    Very useful. Helping me in my biochem professional exam

  • @warnakulasooriyagesugathch9094
    @warnakulasooriyagesugathch9094 3 месяца назад

    OMG, great explanation. Thank u very much. Im frm Sri Lanka.

  • @khatrifatima4669
    @khatrifatima4669 Год назад +1

    You are a gem❤️😇Thankyou Professor!❤️You nailed it to my head!🥰🥰

  • @fatimamalik4997
    @fatimamalik4997 3 года назад +1

    U are totally best.I hate biochemistry before but after listening u aaaahhh.I LOVE BIoCHEMISTRY

  • @claudiagadelho9035
    @claudiagadelho9035 8 месяцев назад

    if it wasnt for you i wouldnt be able to pass my biochemistry degree, im in the second year and passing all my subjects thanks to you, thank you ninja nerd

  • @alevelsdemystified3410
    @alevelsdemystified3410 4 года назад +1

    This was very interesting.I appreciated your clarification of the conditions i.e. fasting state and acute stress state when fat mobilization is happening.The elucidation of the three enzymes involved Adipose triglyceride lipase,Hormone sensitive lipase and Mono-acyl glyceride lipase was very helpful. In lippincot,the regulation via the GPCR-cAMP second messenger system(activated by epinephrine) is mainly directed at the HSL,I hope you can clarify that for me.Such a helpful video.

  • @nelsonomondi5941
    @nelsonomondi5941 Год назад

    Indeed you are a profesa . Teaching biochemistry of headed is not a joke

  • @Billionarethings
    @Billionarethings 4 года назад

    wowwww....no words...excellently explained....really gonna help me in my viva tomorrow...thank youuuu soooo muchhhhh

  • @user-fm8tn6cw2e
    @user-fm8tn6cw2e 7 месяцев назад

    Thank you for this excellent unpacking of lipolysis ! ... Neat and precise.

  • @rahafalhalabi360
    @rahafalhalabi360 6 лет назад +3

    i like your enthusiasm way in your explanation so great :)

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад +1

      +Rahaf Alhalabi thank you!!! thank you so much for your kind words I'm so happy that we were able to help!

  • @khadigamohamed117
    @khadigamohamed117 3 года назад

    I am very happy to listen to your vedios and found them very helpful to me.
    Thank you ninja for this great explanation.
    From Egypt.

  • @alirezaahmadi1777
    @alirezaahmadi1777 2 года назад

    I really dont know how to appreciate you ! You made metabolism easy for me . Thanks a milion 😍❤

  • @mikekhumbomsimuko9227
    @mikekhumbomsimuko9227 Год назад

    Thank you very much
    May God bless you for taking your time to educate different people in the world ❤

  • @SlaughterALABAMA
    @SlaughterALABAMA 4 года назад +1

    Thank you so much 😩😩😩 I’ve been struggling with this for yearsssss

  • @okodioscar7518
    @okodioscar7518 2 года назад

    Thanks so much for ur work, this is the best medical channel

  • @miramiya-hj9so
    @miramiya-hj9so Год назад

    thank you from africa, i'm studying in french but i can understand your videos.thank youuuuuuuuuuuuuuu a lot

  • @AbdullahAsif-sw4yf
    @AbdullahAsif-sw4yf 2 месяца назад

    INCREDIBLE HANDS DOWN 😊

  • @mshaik435
    @mshaik435 6 лет назад

    You are the best and you make things so clear and simple❤️❤️❤️❤️. I beg you to never stop what you are doing please. 🙏🏻🙏🏻🙏🏻May God continue to bless you 🙏🏻

  • @sharonkende4774
    @sharonkende4774 2 года назад

    thank you for this great review of mobilization of triglycerides.

  • @ericloderichs1480
    @ericloderichs1480 9 месяцев назад +1

    Brilliant, thank you

  • @motivo-academy
    @motivo-academy 6 месяцев назад

    Love this presentation. Really well explained!

  • @sseno4993
    @sseno4993 2 года назад

    Omg, thx for breaking this down, when professor understands the topic himself well then students also will understand! Low grader prof-low himself😬

  • @kashafshahid5884
    @kashafshahid5884 3 года назад

    Thank you soo much for such masterpiece... Fruitful than so called online lectures in this pandemic 🤧

  • @s9plus603
    @s9plus603 Год назад

    Just how beautifully you explain with all your heart 🌟🌟🥺🥺

  • @mdimrannoor4765
    @mdimrannoor4765 2 года назад

    I’m gonna be your patron from this semester

  • @ultimatebjj
    @ultimatebjj 6 лет назад +2

    Amazing! Your knowledge is admirable.

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад

      +TeamMaxwell JiuJitsu thank you so much for your kind words I'm so happy that we were able to help!

  • @atiqkhattak7040
    @atiqkhattak7040 Год назад

    Fantastic explanation.

  • @hakanyusufarslan9631
    @hakanyusufarslan9631 5 лет назад +9

    CAN YOU SHARE THE FINAL DRAWING ON THE BOARD AS PDF FORMAT PLEASE? THANK YOU VERY MUCH YOU ARE AMAZING

  • @user-oe9nc9ex1w
    @user-oe9nc9ex1w 3 года назад

    your videos really help with my biochemistry

  • @goneawayanon
    @goneawayanon 3 года назад

    Keep up the good work, best biochemistry class i've ever seen!

  • @charmekachilds2941
    @charmekachilds2941 6 месяцев назад

    Great explanation!

  • @AnjaliSharma-el2kg
    @AnjaliSharma-el2kg 4 года назад

    Hey Ninja Teacher 😊😊
    Your teaching way is awesome, you made biochemistry interesting I loved it.... Thanku so much

  • @janbohm5905
    @janbohm5905 5 лет назад +10

    That perilipin and CGI together looks like a turtle :) Nice vid as always

    • @szarinadaylenavarro9846
      @szarinadaylenavarro9846 3 года назад

      yes! with the phosphates as the feet! I will forever see it that way now. No way to forget it hahaha, thank you!

  • @RobbinJane
    @RobbinJane 4 года назад +6

    I always hear alright engineers at the end of the video.
    Only today I realized he says: ninja nerds 😂

    • @nm2281
      @nm2281 3 года назад +1

      lol

  • @aarfakhan4473
    @aarfakhan4473 3 года назад

    Yes i am injoying your video bzc you make it simple form🤷‍♀️thank you so much sir

  • @michelle-initaliapuoi6715
    @michelle-initaliapuoi6715 4 года назад

    Just thaaank you so much from Italy 🇮🇹, this channel is really amazing!!🙏🏻 Grazie

  • @ashihappysoul2851
    @ashihappysoul2851 Месяц назад

    Great explanation

  • @ritawatitjakrawala5933
    @ritawatitjakrawala5933 4 года назад +1

    Wow, thank you so much, best explaination.
    Could you tell where the video about lipid droplet formation in adipose tissue?

  • @matteobergmann1058
    @matteobergmann1058 4 года назад

    Dude! I´m german and my english isn´t the best but your way of explaining things is so easy to unterstand! You saved my ass!

  • @Happy_girl24
    @Happy_girl24 3 года назад

    Amazing video I love how you went into great detail. Thank you so much.

  • @debraclogston9379
    @debraclogston9379 2 года назад

    This helps. Thank you.

  • @Dr.Abhimanyu
    @Dr.Abhimanyu 3 года назад +2

    thanks for the wonderful lecture (as always)
    i've got a question. is it healthy to lose fat through a ketogenic diet, by fasting, or by reducing carbohydrate intake, as you mentioned?

  • @hayaa.6545
    @hayaa.6545 4 года назад +1

    god bless you. Thank you so much. You guys are best

  • @proudindian5750
    @proudindian5750 6 месяцев назад

    You are my saviour ❤

  • @omermohammedomer4017
    @omermohammedomer4017 2 года назад

    Wow Wow ..... you are Exceeding my Expectations every time ⌚ I hope the best for you.
    I have a question ?
    Long-chain fatty acids are shuttled into the mitochondrial matrix by formation of acylcarnitine esters; catalyzed by carnitine acyltransferase. ... is that mean the fatty acid converted to acylcarnitine esters first then enter the mitochondria?.
    thanks.

  • @chrizzamaebritanico2378
    @chrizzamaebritanico2378 4 года назад

    binge-watching for the whole day :)

  • @chiagochilagorom2206
    @chiagochilagorom2206 5 лет назад

    Most helpful video, i appreciate coming here to learn.

  • @imadullah7020
    @imadullah7020 2 года назад

    Good explanation sir ,
    God bless you

  • @Kesenschaf
    @Kesenschaf Год назад

    THANK YOU SO SO MUCH !!

  • @Runeansfelt
    @Runeansfelt 4 года назад +1

    Very interesting. What are your background for teaching on the subject? And what scientific statements based on? Can you refer to relevant scientific articles on this issue?
    Hoping to learn more from you guys. Just found you guys on YT 👌🏻

  • @dibyasattwakarmakar
    @dibyasattwakarmakar Год назад

    Thank You , Sir 😊

  • @Bladerunner5434
    @Bladerunner5434 5 лет назад

    Great vids- I hope all goes well for you.You really know your subject matter well.Very impressive how you can viewer attention.--Thanks

  • @thelonelymedico
    @thelonelymedico Год назад

    thanks for the lecture

  • @OmarAlhelwani
    @OmarAlhelwani 9 месяцев назад +1

    You are the best

  • @jasleenkaurkaurlove
    @jasleenkaurkaurlove 4 года назад

    love the work! I just can't stop laughing at how he says "ADEPOCYTE" instead of "ADIPOCYTE" cracks me up every time!

  • @muhammadjunaidali769
    @muhammadjunaidali769 2 года назад

    mind blowing explanation.

  • @user-fv8rw8jf9e
    @user-fv8rw8jf9e 3 года назад

    You are very helpful to me..

  • @diellzahyseni8191
    @diellzahyseni8191 3 года назад

    Thank you I understood it very well

  • @fabian116
    @fabian116 2 года назад

    What a master class!!

  • @maryamrahim342
    @maryamrahim342 3 года назад

    Amazing .u make it so easy 🥺 thnk u

  • @888167
    @888167 5 лет назад +1

    Great video as always thanks dude.
    Only one thing: As far as I know the HSL cuts the FA in Position 3 not in Position two. The order is:
    ATGL: 1
    HSL: 3
    MGL: 2 :)

    • @kurtevh2
      @kurtevh2 4 года назад

      nope, the MGL breaks down the last FFA bond, it is called Monoacylglyceride Lipase because it breaks Monoacylglycerides, which means it has only 1 fatty acid. Cheers!

    • @sizamchopa5961
      @sizamchopa5961 3 года назад +1

      @@kurtevh2 great answer good job bro nerd

  • @nm2281
    @nm2281 3 года назад

    fantastic videos

  • @muhammadmoar3788
    @muhammadmoar3788 3 года назад

    Amazing Video 🙂

  • @CristobalBragagnolo
    @CristobalBragagnolo 2 года назад

    Hmm that ester bond looks goood ;)... Thanks mate, awesome video

  • @mayankshetty5092
    @mayankshetty5092 4 года назад

    mind bown bro
    that amazaing ending lol
    i wish i could chat with u all about my doubts would be a big problem solver
    thanks for making these amazing videos

  • @justahuman4862
    @justahuman4862 4 года назад

    Great video.

  • @AhmedDahik
    @AhmedDahik Месяц назад

    May allah guide you to the best dr.zach❤

  • @ahmedmubdir1258
    @ahmedmubdir1258 4 года назад

    thanks from the deep of my heart

  • @hellomonday4427
    @hellomonday4427 Год назад

    You save my life 🤘

  • @MUNEEBO
    @MUNEEBO 3 года назад

    THANKKKKK YOUUUUUU SO FREAKIN' MUCHHHHH

  • @JennyErica64
    @JennyErica64 3 года назад

    I love this video .... so interesting to learn biochem 😍😍

  • @jackjyoung
    @jackjyoung 3 года назад

    You always do a great job! Thank you.

  • @FLJD427
    @FLJD427 6 лет назад

    Thanks. Good video. I had no prior knowledge that not only does the body break down protein LBM into glucose via GNG but can also do it as a consequence of Lipid breakdown into glycerine and its 3 fatty acids by free transport of glycerine to liver via a similar GNG process used to convert protein/LBM.
    ATP seems to be the most common primal fuel at a cellular level but the cell mitrochondria seems to have a multi-fuel capacity to handle ATP, Fatty Acids and Glucose (and perhaps some primitive alcohols too?). Begs the question if we can biohack our ratios of mitochondrial specializations to get more preference for fat vs glucose vs ATP etc as a specialization of our own lifestyle and modify it over life by targeted nutrition, supplementation and exercise type (anabolic/HIIT, resistance training styles); or to modify our preferred bio fuels to compensate for metabolic disfunctions arising from age related signaling in-sensitivities, disease, injury etc.
    Question: How long do the circulating albumin protein "boats" stay in situ being recirculated pending cellular uptake into LBM or active tissue before they are declared "past shelf life" or "in excess of overhead to manage them" and shuttled back into body fat? Seems like the blood stream is being used as a kind of transient energy queing/buffering system but it must have much less volumetric capacity than lipid storage cells otherwise arteries would sprout fatty deposits as more localized and accessible auxiliary fat storage systems (surprised there are no cancers that mimick this phenomena).

  • @mahesarasifali6268
    @mahesarasifali6268 5 лет назад

    Really helpful 😊😀

  • @deblang2276
    @deblang2276 3 года назад

    Thank you...enjoyed...I just got onto fasting lifestyle and main reason is to burn my body fat...I just took a bloodiest and my trigs were very high coming off a 48 hr fast!! I have seen tryglycerides come down from burning fat...in others helpful charts...will I always have fat left to burn...but not in overabundance? I do not want to take meds..I will be watching your other videos hopefully to find the answers..thx again so much :)