shRNA mechanism | short hairpin RNA mediated knockdown and gene silencing

[@jwoob4576]

I really appreciate your lecture. I'm highschool student from southkorea and your lecture makes me feel knowledgeable...

[@mggaming8239]

I am also a professor but I really appreciate the way you teach, it's really simple and clear, I ask my students to watch ur videos. God bless you dear

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@tdsdesa]

Sir I have tell you that your lectures are incredibly useful and effective. Thank you for all your efforts, greetings from Italy.

[@justsue7062]

Amazing! You never cease to amaze me. Lots of love from Malaysia..

[@shomusbiologyofficial]

You're welcome. Glad you like it

[@kimiaslk9348]

You are a great teacher
Thank you for making these videos 🙏

[@shomusbiologyofficial]

You're welcome

[@krishnant6249]

U realy appreciate u r knowledge..simply explanation.......thank you sir....

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@mayukhroy5393]

Sir , you made all my doubts clear .

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@diogomarques7479]

Very well done. Thank you for sharing your knowledge

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@rajlaxmiprasad7087]

Respect for you

[@archanakumari1429]

Nice explanation. Thanks for your knowledge sharing.

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@ChryslerPTCruiser]

thanks! really helpful

[@emilyvfletcher9519]

Thank you!

[@rohitkumar-et3np]

thnk u brother...

[@Raheisi]

drosha activity should be highlighted sir

[@piyalidas8514]

Sir, RNase H activity of PIWI domain recoginzes dsRNA and cleaves only the target mRNA. Why RNase H cut the target mRNA but not the shRNA or miRNA? Is there any recognition site or something for which RNaseH can recognize that it's the target mRNA and it have to cut and not the shRNA?

[@sohasabry6952]

thanks

[@eunicetan5960]

hi how does dsrna get passed on to progeny cells?
thankyou for all the efforts,sending love

[@shomusbiologyofficial]

Don't pass on to progeny cell

[@eunicetan5960]

@@shomusbiologyofficial ohhh alright because i got confused after reading the 1997 research paper ,thankyouu for the reply :))

[@pratibhasharma2588]

Sir please upload video on pi rna

[@parthaprotimkarmakar9227]

Please make a video on piRNA

[@shomusbiologyofficial]

Okay

[@rubinjoseph5850]

the only difference from your siRNA video is the initial structure of the dsRNA intermediate before incorporation in to RISC, is that right?

[@ASHUTOSHKUMAR-ne1yl]

Rubin Joseph yes

[@abhijitpaul8509]

if the target RNA is double stranded,then what happen.

[@sudarshanreddy5115]

😎sir

[@indiamusically]

Argonaute~RNaseIII or Argonaute~RNaseH?

[@mampidutta327]

Shanu Brahma rnaseh

[@ASHUTOSHKUMAR-ne1yl]

Shanu Brahma H

[@ASHUTOSHKUMAR-ne1yl]

RnaseH