miRNA biogenesis | microRNA mechanism

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  • Опубликовано: 20 фев 2015
  • This lecture is about the mirna biogenesis and mechanism and the role of microrna in cancer.
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    Thank you for watching

Комментарии • 232

  • @monikajha3894
    @monikajha3894 3 года назад +23

    You are living encyclopaedia.. great job sir... best teacher with good content and excellent teaching skill😊

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 года назад +3

      Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures

    • @nelsonmv6510
      @nelsonmv6510 3 года назад

      Thank you sir💯💯💯💪💪💪

    • @chrisbarouky4235
      @chrisbarouky4235 Год назад

      ​@@shomusbiologyofficial 3325400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000⁰0000000000000000000000000000000000000000000000⁰000000000000000000000000000000000000⁰⁰⁰00000000000000000000000000000000000000000000⁰0000000⁰000000⁰0000000000000000000000000000000000000000⁰000000000000000000000000000000000000000⁰000000000000000000000900000000000000000000000000000000009000000000000q

  • @rikdas6639
    @rikdas6639 3 года назад +3

    From my high school times to my present Masters days, you are the longest-running teacher of mine.
    Thanks for everything Somu!

  • @shivakishor1033
    @shivakishor1033 5 лет назад +30

    Really u r a library sir....thank u sir thank u soo much its helping me more than online classes.

    • @shomusbiologyofficial
      @shomusbiologyofficial  5 лет назад

      Glad to hear that you are getting benefit from the videos. Please subscribe and share

  • @ilsehofstee9869
    @ilsehofstee9869 4 года назад +19

    I use your lectures for literally every subject of my education. Thank you so much! Greetings from the Netherlands

  • @jaxnean2663
    @jaxnean2663 8 лет назад +1

    Totally clear and informative, great job!

  • @evildoesnotsleep-x2b
    @evildoesnotsleep-x2b 8 лет назад +5

    this video is extremely helpful. thank you
    would you consider doing one with miRNA and its affect on cancer?

  • @gibcote
    @gibcote 9 лет назад +20

    brilliantly explained!
    P.S. RISC stands for RNA induced silencing complex.

    • @iwaynejames
      @iwaynejames 4 года назад

      induced/interfering, same thing is communicated in his explanation.

  • @zeeshanrasoolkhan
    @zeeshanrasoolkhan 5 лет назад

    salute!!!! explained brilliantly in simplified way...

  • @HaidaSOD
    @HaidaSOD 9 лет назад +1

    Wonderful lecture! Thank you!

  • @bpuja11
    @bpuja11 9 лет назад +2

    its awesome sir......ur all videos are very well explained & help me so much...

  • @ArlindaOfficial
    @ArlindaOfficial 6 лет назад

    Thank you, this is really helpfull! keep going

  • @emicalato4142
    @emicalato4142 9 лет назад +1

    thank you sir.. it was very helpfull

  • @pratibhamali3845
    @pratibhamali3845 8 лет назад +1

    amazing lecturer

  • @alwinaanam1231
    @alwinaanam1231 7 лет назад

    awsome video.................love to watch it again n again

  • @Appamkrishna
    @Appamkrishna 7 лет назад

    This video is very helpful and now i understood actual gene silencing mechanism. Thank u very much sir and u have good explanation skill.

  • @yashcool2627
    @yashcool2627 3 года назад +1

    I am a pharmacy postgraduate working in a biotech company. Your lectures are a great help to me for learning the biotechnology basics. Thank you

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 года назад +1

      You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

  • @ghofranbagher3924
    @ghofranbagher3924 9 лет назад

    thank you , it was very helpfull

  • @Serene97464
    @Serene97464 3 года назад

    Thank-you so much Sir for this easy-to-understand explanation, I'm sure I can remember this for longer period of time. Again Thank-you for your Time and Support.

  • @rajnishkumarsensen1034
    @rajnishkumarsensen1034 6 лет назад +1

    very helpful video it is..... Thank you sir......

  • @InvincibleKuldeep
    @InvincibleKuldeep 2 года назад

    Wow, what a great learning experience of miRNA mechanism...with you Sir...Thanks a lot

  • @stefandanev8117
    @stefandanev8117 7 лет назад +1

    had to describe the whole process at the exam.thanks for the help

  • @candicetang1991
    @candicetang1991 7 лет назад

    thx a lot, that is really helpful.

  • @drishtisarkar6422
    @drishtisarkar6422 4 года назад +1

    Great teacher god bless you

  • @sirishas7507
    @sirishas7507 3 года назад +1

    Such a clear explanation!!! I use your lectures as a guide for my Master's prog in the USA. So grateful to you. Great job!!!

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 года назад +1

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @jiakhattak5929
    @jiakhattak5929 7 лет назад +1

    good job. i have a strong feeling that ur teaching style is inspired by Dr. Najeeb...

  • @alwinaanam1231
    @alwinaanam1231 7 лет назад +1

    very helpful... thanks...

  • @yatagan1
    @yatagan1 5 лет назад +1

    It is really perfect explanation. I am really so glad to watch it. thank you

  • @Shwetat04
    @Shwetat04 7 лет назад

    The way you explain is simply impeccable..
    Thanks a lot! 😊

  • @beech9443
    @beech9443 8 лет назад +6

    indeed good explained really clear and easy to comprehend, but at beginning you said slicer protein has RNase H, and somewhere to the end when explaining miRNA-mRNA duplex, you said argonout has RNase H activity? :/

  • @xirasen
    @xirasen 7 лет назад +1

    This is really helpful. I bet this is the most easy, well-explained video on youtube about miRNA :D
    Since I'm not really good at English, would someone explain why the last progress is important?

  • @nidhikumari9126
    @nidhikumari9126 5 лет назад

    Thanku so much gurujii.....u helped me a lott.....i was nt able to understand the mechanism of rna from book it is totally exausting 4 me but when i found ur video nd after watching ur lecture i understand all d things ......thanku so much sir..🙏

  • @shwetakaur9956
    @shwetakaur9956 6 лет назад

    Very nice explanations

  • @alwinaanam1231
    @alwinaanam1231 7 лет назад +1

    very helpful

  • @tasbeehazarrin6463
    @tasbeehazarrin6463 6 лет назад

    Very good explanation really

  • @Megha-ij8eo
    @Megha-ij8eo 3 года назад

    This lecturer is really very helpful for me...thank u so much sir...😊👌👌👌

  • @alwinaanam1231
    @alwinaanam1231 7 лет назад

    awesome video.. thanks a lot BT it seems u change the function of piwi n paz domain... if possible plz reply

  • @muneebaumar7173
    @muneebaumar7173 3 года назад +1

    I am an MBBS student and ur videos are amazing .No words to admire your teaching style.Keep it up sir.

  • @kavita232410
    @kavita232410 4 года назад +4

    THANK YOU! This is the best explanation I have seen so far. You should be a professor at IISc or something!

  • @alwinaanam1231
    @alwinaanam1231 7 лет назад +3

    very helpful.......thanks a lot

  • @SohanurRahman09
    @SohanurRahman09 6 лет назад

    Nice presentation

  • @irenetan3620
    @irenetan3620 3 года назад +2

    Thanks, very helpful. What can you suggest for my review, be taking comprehensive exam for my PhD soon. Thanks.

  • @ritikasingh8809
    @ritikasingh8809 3 года назад

    Very much cleared after watching ur vdo

  • @muhammadashrafhadirosman3845
    @muhammadashrafhadirosman3845 3 года назад +1

    You really good in explain it all even no matter how hard to understand it

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 года назад

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @jayaprakashc.a2941
    @jayaprakashc.a2941 Месяц назад +1

    Your knowledge in diversity is administerable

  • @zhoufang2276
    @zhoufang2276 5 лет назад +1

    great lecture, thank you so much

  • @Arabzai321
    @Arabzai321 Год назад +1

    Love you Brother from Afghanistan 🇦🇫
    That was an Informative Video about RNAi and its Types.
    Thank you so much for your help.

    • @shomusbiologyofficial
      @shomusbiologyofficial  Год назад +1

      Glad to hear that you are getting benefit from my lectures

    • @Arabzai321
      @Arabzai321 Год назад

      @@shomusbiologyofficial
      🥰😍🥰❤️❤️❤️

  • @hebaabdelgawad8193
    @hebaabdelgawad8193 7 лет назад +1

    Thank you for your effort

  • @ozzytubes7955
    @ozzytubes7955 7 лет назад +1

    thank you for explaining it so clearly

  • @ridasaleem5088
    @ridasaleem5088 5 лет назад +1

    Awsome.. U have explained it very well

  • @Thor616marvel
    @Thor616marvel 5 лет назад +2

    These videos cleared all my dought thanks sir

  • @mayukhroy5393
    @mayukhroy5393 4 года назад +1

    This video was soo helpful Sir.

  • @agrigpb
    @agrigpb Год назад +1

    Great Job

  • @sravanichitneedhi8044
    @sravanichitneedhi8044 3 года назад +1

    Sir, u made it easy . Thank u , and keep making more lectures . Specially these lectures are more helpful in present covid situation because we are not attending the offline classes of my institutions.

  • @priyankasingla1071
    @priyankasingla1071 3 года назад

    Thank you

  • @drsandywareable
    @drsandywareable 8 лет назад

    nice lecture

  • @abarouca
    @abarouca 4 года назад +2

    Thank you for the brilliant explanation! Your didactics to teach is great! I have a doubt, and would appreciate if you can help me (I need to solve for my internal PhD defense): are we producing miRNA all the time, or do we need a stimuli to produce it? More specifically talking, are there some kind of food which could make us to produce it? For example, could be that a high adherence to a healthy diet and its phytochemical could "silence inflammatory genes" through the production of some specific miRNAs, which interfere with mRNA of genes related to inflammation (e.g. CRP)? So, in case there is this interference, the mRNA of CRP will not be translated, and so the concentration of CRP in blood will be decreased by this mechanism. Is it correct?

  • @tracyanncampbell7367
    @tracyanncampbell7367 3 года назад +2

    Good video. Thank you.

  • @kalpanamurmu3776
    @kalpanamurmu3776 5 лет назад +1

    Thank you sir. I very much helpful from this vedio.

  • @prithwirajsutradhar6757
    @prithwirajsutradhar6757 4 года назад +1

    Very very helpful video .Thank u sir

  • @aarthipalanisamy9839
    @aarthipalanisamy9839 6 лет назад

    I liked ur lecture Sir.. R u able to give a lecture regarding TILLING & eco-TILLING

  • @shivangitiwari7541
    @shivangitiwari7541 8 лет назад

    I Like it..!!!

  • @latifesoltani1653
    @latifesoltani1653 2 года назад +1

    Thank u very much,you help me whit this video very very much because I had seminar about miRNA at university …🙏🙏

  • @sarahhamdy5752
    @sarahhamdy5752 9 лет назад +24

    Nice video
    NB: You are saying 3' overhang while you are drawing a 5' overhang !

    • @antaryamiacharya5657
      @antaryamiacharya5657 5 лет назад

      What is double stranded RNA , in which type organism it seen or it created in any type of cell depending on situation, what it's role and function. Plz make a specific video on DS RNA.

    • @aseemsharma6464
      @aseemsharma6464 4 года назад +5

      Also... Full form of RISC is not RNA interference silencing complex.. it's RNA induced silencing complex

  • @main-a
    @main-a Год назад +1

    Thank you sir. I really love watching your videos , it gives us so much of knowledge. You are awesome.

  • @subhamkarmakar3320
    @subhamkarmakar3320 3 года назад +1

    Amazing sir

  • @jilmilmahanta3669
    @jilmilmahanta3669 7 лет назад

    sir u r great.. thank you so mch fr ds video.. i learned a lottt frm it ☺

  • @ankitasiddharth6038
    @ankitasiddharth6038 Год назад +1

    Nice... well explained sir

  • @akshaybharti7361
    @akshaybharti7361 3 года назад +1

    Though there were some mistakes like in full form of RISC and regarding the overhanging sites. But I loved your way of teaching, you cleared my doubts.
    You are a good teacher 👏👍

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 года назад

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @Dr.FaizanMirza
    @Dr.FaizanMirza 11 месяцев назад +1

    simply wow ❤❤

  • @mayooran8653
    @mayooran8653 6 лет назад +1

    Amazing

  • @Dr_Durrani
    @Dr_Durrani 2 месяца назад

    Great job. Just one correction the overhang is at 3' but shown at 5'. I am sure you may have already realized that 😊

  • @subhamkarmakar3320
    @subhamkarmakar3320 3 года назад +1

    Excellent 🔥

  • @jenny77054
    @jenny77054 5 лет назад +1

    So precisely described 👌

  • @priyankasingla1071
    @priyankasingla1071 3 года назад +1

    Sir, it is a humble request to explain identification (bioinformatics tools) of micro RNAs (miRNAs) and mRNA targets.
    Thank you in anticipation

  • @pawanbakthiyal2759
    @pawanbakthiyal2759 5 лет назад

    thanks sir

  • @samikshyapradhan2533
    @samikshyapradhan2533 5 лет назад

    Very good explanation sir. You make rna easy to understand 😊.

  • @triplecleff
    @triplecleff 6 лет назад +1

    thank you

  • @dr.anshugupta9336
    @dr.anshugupta9336 4 года назад +1

    Well Explained

  • @asmaaelgedawy7643
    @asmaaelgedawy7643 5 лет назад +1

    Thank you very much you help me so much

  • @shilpasharma7303
    @shilpasharma7303 2 года назад +1

    you are a great teacher🥺

  • @nawazmahmud8535
    @nawazmahmud8535 8 лет назад

    have any lecture about Biogenesis of Piwi RNA?
    please help me by giving the link

  • @jibanpal4136
    @jibanpal4136 3 года назад +1

    Very good

  • @Divyajyoti__
    @Divyajyoti__ 3 года назад +1

    Thank you so much sir 😊❤

  • @anilmalik7995
    @anilmalik7995 6 лет назад +1

    Very good lecture Sir, can you pls tell me which book I can follow for detailed RNAi

  • @tsionberhane4783
    @tsionberhane4783 2 года назад +1

    I don't know why I pay for college honestly. God bless you!

  • @ahmedeldesouky1878
    @ahmedeldesouky1878 5 лет назад +1

    THANK YOU SO MUCH

  • @meerz9343
    @meerz9343 3 года назад +2

    Very nice sir 👍

  • @aayushphadte
    @aayushphadte 4 года назад +1

    *_clean_*

  • @beenaasokan8569
    @beenaasokan8569 7 лет назад

    you are great! 👍 Sijo.A

  • @dannykelly7789
    @dannykelly7789 9 лет назад +2

    You are awesome sir. All of your videos help me so much in my genetics class I wish I had you as the professor

  • @rimasamanta4778
    @rimasamanta4778 7 лет назад

    sir...it is awsm....😊.Sir..is there any...online tests are carried out for iit jam..in ur institute???

  • @sounakdasgupta64
    @sounakdasgupta64 6 лет назад

    Will it be a 3'overhang or 5' overhang?

  • @wycliffenyandika9017
    @wycliffenyandika9017 Год назад

    I feel good after watching this, do you have video about transcription explaining why lagging and leading strand ?

  • @abdou9888
    @abdou9888 4 года назад

    Is there a video to explain how scientists use this process to edit genome ?

  • @ashishbissa1803
    @ashishbissa1803 6 лет назад +1

    What is the work of passenger strand

  • @usgallery5428
    @usgallery5428 5 лет назад +1

    Is there any recognition mechanism for RNase H to cleave only targeted RNA not mi RNA?

  • @sajidachaudhry5039
    @sajidachaudhry5039 3 года назад +1

    He is very very outstanding lecturee, may Allah Pak blessed you☺️

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 года назад +1

      Thank you so much for appreciating my efforts

    • @sajidachaudhry5039
      @sajidachaudhry5039 3 года назад

      @@shomusbiologyofficial actually i am from pak, may i get your personal contact if you never mind dear sir, actually i wanna discuss regarding to my study

  • @joanne7699
    @joanne7699 3 года назад

    Hi, can I ask is there any way the target mrna can prevent the miRNA from binding to it to protect itself from degradation?

  • @arpitadas188
    @arpitadas188 6 лет назад

    sir i have a question , RNase H is an enzyme used to cleave the RNA-DNA duplex ,but the arganaut (RNase H activity)cleaves ds RNA ...how so ? didnt the specificity got altered ?

  • @khuloodalasiri1
    @khuloodalasiri1 8 лет назад +1

    thank you so much for this video it was really helpful for me to understand what is exactly Micro-RNA and how it is produced