miRNA | micro RNA mechanism of gene silencing
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- Опубликовано: 28 ноя 2020
- miRNA | micro RNA mechanism of gene silencing - This lecture explains about the details mechanism of miRNA gene silencing. The process of micro rna or miRNA mediated gene silencing will be clearly explained with the help of this video lecture. Microrma is a type of rna interference or RNAi type of small double stranded rna with endogenous origin inside the cell and it cleaves target rna before the translation process. Stay tuned to this video to learn the following -
What is Microrna?
How micro rna produced?
How micro rma works?
Microrna mechanism
MiRNA mediated gene silencing mechanism
Principle of miRNA mediated gene silencing.
This lecture will be helpful for CSIR net, Gate, icmr jrf, ICAR net, bet, JNU, ncbs, IISER PhD entrance exams.
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Thank you for watching the video lecture on microrna mediated gene silencing also known as the miRNA mediated gene silencing in cell. This lecture will be helpful for CSIR net, Gate, icmr jrf, ICAR net, bet, JNU, ncbs, IISER PhD entrance exams.
I have been studying from your videos since my first year. I am in my last sem of my masters preparing for csir. And your videos are still getting better day by day. Keep growing and helping students ❤️
Thank you so much for appreciating my efforts
That's just the right timing! Thank you for the recap.
Your lecture is very helpful. Keep shining 🙂
Do all supressor genes have the same function of p53 to activate pri-miRNA and thus produce specific miRNA that ultimatley degrate target mRNA?
Thank you sir for recalling the concept 😊
Thank you
Thank you sir...😊 From today I will be your regular student....
Glad to hear that you're getting benefit from my lectures. Please subscribe and share
I liked it more when you used the white board. Thanks for your help as always!
Thank you
just have been going through this topic sir ..valolaglo as usual 🙏
You're welcome. Glad to hear that you're getting benefit from my lectures
How do you Inhibit the expression of mir-16 and mir-135a in the dorsal raphe? Both of these mrna's are increased by ssri's which suppresses sert and causes pssd.
May you please say what are mirtrons? Are they a part of the RISC or they can only become a part of the RISC only after being converted to miRNA?
Thank you! 🙏❤
You're welcome
Outstanding vdo sir....easy to understand
Thank you so much for appreciating my efforts
sir you is my best teachers,, big thankyou for your conetnt
are*
Very nice explanation and very very helpful video, thank you so much sir ❤🎉
You're welcome
Dada.. Thank you so much for everything..I'm going to work as Microbiologist in "COVID19 Testing Center" at Wales, United Kingdom from next week..tar Aage tomar SARS CoV-2 er Videos gulo ar ekbar revise korlam..it's really helpful as always.. Thanks once again..jotobar thanks bolbo it won't be enough..
That's good opportunity. All the very best
@@shomusbiologyofficial Thank you Dada 🙏
tmw I will pass in Xam bcoz of this one man
All the best
Thank you very much for your lectures.. and also please do video on MRSA & anotamy and physiology videos..
Okay. Thank you
3rd comment.... Sir i just want to say you a "Big Thankyouu for every lecture"💞💞💞
Thank you so much for appreciating my efforts
too good bro too good...❤❤
Thank you so much for appreciating my efforts
Can u provide a vdo regarding microbiology..as i think I've interested in this only plz provide a short knowledge via vdo obviously that what is microbiology nd what is all about,?
Thank you so much sir 🙏🙏🙏
You're welcome. Glad to hear that you're getting benefit from my lectures
Perfect 👍🏻 thanks
You're welcome
Great work sir
Thank you
Please I Pray that you live a very long life the world's doctors need you
Dear sir we are waiting for your video about CSIR cutoff prediction for June 2020?..hope you release soon..
bro what is diff between human rna and covid rna???
is there any way to remove virus Rna when ot released inside cell??
I pay college but learn from you. Thank you so much sir ☆
Thank you so much for appreciating my efforts
Thank u sir❤
You're welcome. Glad to hear that you're getting benefit from my lectures
Can you explain the role of miRNA in obesity.Also which are the clinical potential miRNA in obesity
what did you mean by high arn?
Presentation ta darunnn...thank you so much dada...😊😊
You're welcome. Glad to hear that you're getting benefit from my lectures
Hi bro , please make video on mutation of SCA disease ,and what we need to do repairs the mutation
Thank you
A huge respect from Pakistan Sir...
Sir I have heard that the AGO2 protein is not activated in miRNA case that's why it's target mRNA either repress by translation fectors or degrade by exonuclease enzymes.
The cleavage will only possible when 100% complementary occur between the miRNA to it's target mRNA which is very rare.
I could be wrong.
Thank you
you are the best in biology and I use your videos as references which can't find anywhere. I liked it more when you used the whiteboard.
Thank you so much for appreciating my efforts
Thanks sir😊👍
You're welcome
hey how mirna is used as tumor suppressor gene?
Thnxs it's good
You're welcome. Glad to hear that you're getting benefit from my lectures
Banger
Happy Teachers Day, Sir.🥰
Thank you
Sir I requested you make a video about cardiovascular disease and drugs
Please sir
Tq sir 🙏
You're welcome
Sir pls make a video on how to design primers for the miRNAs
Sure
WHY IS IT ONLY 19 TO 24 BP DOESNT THE miRNA SIZE DEPEND ON THE GENETIC MATERIAL LENGHT THAT IT IS SILENCING?
Hello Sir can you make a video about Modeller software
& how to run a sequence lThank you
Later
different mode of gene silencing by mi rna mean
Kindly sir make a vedio on RNA silencing by siRNAs
Sure. Next video
Hello sir I'm Anup studing Bsc in Bangalore , just now I watched your video on mechanism of miRNA in that you said that the PIWI domain of Argonaut has catalytic motifs that actually cleaves the phosphodiester linkage
But i watched another animated video for simple visualisation in that they said that 5' end which is attached at PIWI domain is not perfectly positioned and cannot cleave mRNA ... instead they said a protein called TRNC 6 containing glycine tryptophan repeats repress translation and cleave mRNASo could please clarify my doubt mentioned above .... I'm getting bit confused that who actually cleaves the mRNA
Thank you sir....u saved me ...😅
You're welcome. Glad to hear that you're getting benefit from my lectures
Plzzzz use white board....thats the best way of getting concepts and i m used to with it also plzzz don't change the format
Thank you
sir can u pls make a video on carbon sequestration..
Okay later
thanks sir..
Me: An American student looking for biology instructional videos on RUclips because my professor doesn't clearly explain the concepts.
Random Indian fellow on youtube: "It's free real estate"
me: german dude starting a PhD involving miRNA and having no clue whatsoever.
MVP Shuman: "finger guns" - you need a recap ? let me explain !
as a little piece of constructive feedback: a clarification you are talking about processes within animals would be bueno :)
Ist view is mine ✌️
Thank you
👍🏻
Thank you
Sir please board use karo is se toda teacher wala feel araha hai, you are doing great as professor on board.
Thank you
Please make the videos are in Hindi version too. Causing I'm unable to understand properly as well not clear the concept or those who are not good in English.
There are plenty hindi channels. I keep mine to English only
The mechanisms are all very nice- but just remember this all means the CELLS are doing this... they invented this process and carry it out- pretty smart isn’t it!!
Yes. Its exciting
Hi
In end of video you are saying siRNA instead of miRNA. Is it by mistake or by siRNA you r indicating same as miRNA???
Need to check. Can be slip of tongue
@@shomusbiologyofficial ok sir, btw video is very informative and in detail. Thank you so much sir for solving my confusion☺.
Sir please start neet crash course
I don't like crash course idea
I mean to say that u are already uploaded human reproduction for neet so plz keep uploading next chapter according to syllabus...many neet aspirant are follow your lecture
Sir Hindi kahia