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- Опубликовано: 31 янв 2019
- Trelegy combines 3 medicines in 1 inhaler and boasts of its prowess as a treatment for COPD - chronic obstructive pulmonary disease. A company sponsored study superficially appears to lend support to this conclusion. Unfortunately looking beneath the headline suggests major questions exist about this horribly expensive product.
GSK sponsored, funded, designed and supported the study. Further potentially compromising the integrity of the investigation most of the authors received financial support from the company, and the lead author was an employee of the drug manufacturer. The study involved about 1200 locations in more than 35 countries ranging from Mexico to Russia, Ukraine, Colombia, Philippines and Peru in addition to several western nations. This widespread distribution of participants calls into question standardization and oversight.
Actually the study cast significant doubt its findings. While the study was designed to evaluate patients with COPD, it also appears to have included asthmatics. A large pool of patients recruited into the study were using inhaled steroids. For many the drug was abruptly discontinued which would be expected to precipitate flares in patients with asthma. According to an accompanying editorial in the New England Journal of Medicine, the study was designed to boost the likelihood of a favorable outcome for Trelegy.
Advertised as a treatment for anyone with COPD now also referred to as COLD - chronic obstructive lung disease - its use should be restricted to only those with the most recalcitrant disease. An international consortium combining talent from the World Health Organization and the National Institute of Health clearly sets the standard for treating COPD. They suggest triple therapy be limited to very advanced cases. Pneumonia is a relatively frequent complication of the inhaled steroid in Trelegy.
Further testifying to a lack of scruples at the company, they have resumed paying doctors to promote their medicines and attend meetings to speak as advocates for the company’s products. This reverses a policy to discontinue these dubious efforts announced in 2012 and supposedly fully implemented in 2016. Making matters more dicey, the company paid a $3,000,000,000.00 settlement to the United States government for failure to report safety issues and improperly promoting its drugs.
Does Trelegy provide sufficient advantages to warrant the cash price at a pharmacy of $627-$708 for a single inhaler? Sounds like the company may be up to its old tricks again.
Trelegy changed my life with emphysema. Nice to have all three drugs in one inhaler. I'm in Canada so our drug costs are much less than the U.S.
I thought Canada had universal healthcare. Or is it healthcare is just less expensive?
@@user-ks4nr9hf6m Universal healthcare, YES, but with drugs, you have to pay. or have medical insurance at work, still a lot cheaper than in the USA it has only become almost free with seniors, age 65... Hospitalization including surgeries, X-rays, and blood tests was free.
***.But lately,, because of waiting time for some procedures ( its happening now fr the past few years, because of doctor shortage, , There are some clinics had been offering PRIVATE that one has to pay with quick appointments..--- BUT, when it's an emergency case, .its a MUST that a patient be attended as soon as possible just like in any other countries,, but of course, in Canada is free hospitalization,,
Diagnosed with severe allergic asthma today after two years of thinking it was bronchitis, histamine intolerance. This is the only thing that works 100%
Why would I need something like this?
It seems like it will fix one thing but mess up 20 other things.
I’m a little scared about trying this now. Always awesome videos
I agree!
I was skeptical about taking this for a while. Now I know I’m not gonna use it. The risk far outweighs any temporary relief it might give. The fact that my doctor prescribed it at the same time he prescribed prednisone.😮😮😮 a big no no according to this man. Seriously it’s bad enough I have very high blood pressure . Killer!!! I’m also on oxygen. 🤦🏽♀️
One if the disadvantages is the 800% markup
My insurance company Paid $40 I asked if that was with my insurance and they said yes I ask how much it is normally they said $800? That’s just ridiculous.
Another greedy pharmaceutical company! Greetings from Australia 🇦🇺
This Dr. is the best!
this is great information. thanks alot.
Wish I had seen your review of Trelegy before today's visit to my pulmonologist. Don't prescribing doctors have the obligation to fully detail a treatments risks versus it's benefits?
Thank you so much!
You're welcome!
Thankyou!🙏
Just took my first dose. Well, it relieved my symptoms of dyspnea upon awakening in the morning. But so does symbacort or ventolin. Yup I am a hopeless smoker. Have quit many times for as long as 2 years. Already have osteoporosis. Not sure how but I will try to stay quit with the cigs.
I believe in you
You can do it!!!
@wellnowdoctor Thank you, very informative! Can you do a video on the breztri ?
This dude scares everyone with side effects on any drug he does a video on
I want to give trelegy a shot my asthma is really bad I'm having a lot of trouble breathing but you're talking me out of it so I have to keep suffering FML
I read the IMPACT study and it appears that those with an asthma diagnosis were not included
Como obtengo la traducción al español
I keep seeing their commercials and I dont know how to get them to stop, I feel harrassed by this big pharma seller
I tried this crap and at the first puff it gave me a screaming headache, so I stopped using it!.
Are there no new drugs we patients can trust?
But why no oral sreroid when absolutely needed?? (Prednisone)
But i have soo mych phlegm.. but my pulmonologist prescribed this for me.. will it work?.. thanks for the info
very informative and thorough but have your opinions been verified and by which medical body?
Im on daliresp as well can u take both??
This seems like the same thing as WIXELA?
I now know why have high BP. I was never high before the doc started me on Trelegy. I am kicking off many pharma products, and this is now another one that Has to GO.
All of these disadvantages whats the advantage??
Kisha Washington 😂. after watching this i wanted to chuck the inhaler onto a cliff. but its scary, cause it is helping me breath better.
Trelegy helps me 💯!!😊👏
I’ve only used Trelegy once and it helped. I’m in love 😍
I know this has nothing to do with the actual product, but Trelegy doesn’t allow comments on their videos and I’d like to speak to the advertising department: you now make me run to the remote to fast forward a NINA SIMONE song because you insist on using it in every commercial run every break. That alone makes me avoid this product.
I like how he breaks this down but I'm not TAKEING breo or trelegy I didn't even smoke just had some Respitory issue that were related to other issues may God have mercy I'd rather anoint my self with oil and pray and seek to eat healthy and do natural health .
Bruh looks like you've been munching on too many of them bhoblate bhip bhewy bookies.
I don’t think he cared much for trelegy
No me sirvió, me quemo la garganta
😢😅
You lost me by promoting the vaccines. How insane! Most of what you say makes sense according the the side effects I personally experience, but to encourage taking vaccines, especially in this time, is beyond STUPID.
Why is one inhaler so expensive..600.oo.Can't buy it when on S.S.please help