Little detail at the end; I believe it’s Beta 2 adrenergic receptors associated with dilation of the bronchioles! Not Alpha 2! Thanks to your video on adrenergic receptors, in your neurology playlist, I was able to learn about these receptors! Thank you for all of your amazing videos!
Ninja I really like your passion talking and teaching about this stuff.. you had me at cortisol.. but when you looked at the camera and said "Glycerol.. BEAUTIFUL" lmao.. I really enjoyed your lecture.. I learned a lot and am a new subscriber.
omg!omg!omg!... this is soo good.... i know medicine is beautiful... connecting everything is way beautiful.... and the way you doo it , just amazing!...u r teaching us taking the body as a whole..... thank soo much for these wonderful videos!!!
Hello there! You are awesome! When I tried to read the books about this topic, I can’t understand the concept. Just by watching his lecture, I was able to say ‘that’s easy to understand’! Now every time I have to read some medical information topic, I have to watch his lectures first then read the book. It makes my life easier😊
i am a ninja nerd addict.however if i am not wrong, i think it is not Alpha2 receptor but the Beta2 receptor that cause broncodilation as against what you have mentioned almost at the end of this video(at 24.50)
I've always avoided your videos because they were super long and i have little time but wow, you answered all the questions i had on this particular topic.Thank you
Your way of teaching is extraordinary and very helpful to millions of medical students and professionals all over the world.You may like to correct the last point where you said Alpha-2 in the bronchial smooth muscle to Beta-2.I really admire you and hopefully one day we will meet in person.
I love watching this stuff (and I'm doing so purely out of curiousity, because I have no qualifications in any of this, but the more I watch & read - the more it makes sense) It is "beautiful".
Sir chromaffin cells don't have axons they are actually post ganglionic cell bodies, and Beta 2 receptors are present on bronchial smooth muscles not alpha 2
I can't believe I didn't find your channel sooner!!! I actually get it now!!!! Small complaint: Please add subtitles! Seeing the words helps me comprehend better ^-^
This was awesome, thank you. Only note is that the main receptors responsible for vasoconstriction, increase HR and BP are the BETA-1 adrenergic receptors (not alpha-1)... and bronchodilation are BETA-2 Adrenergic receptors (not alpha-2).
+Kayla Akemi As for your comment alpha-1 adrenergic receptor's do play in important role in constricting blood vessels which would cause the increase in peripheral resistance and therefore an increase in blood pressure. Also by constricting certain blood vessels we can divert that blood to the more vital organs. The beta-1 adrenergic receptor's are generally only present on the myocardium of the heart as well as the Juxtaglomerular cells in the kidney this allows for us to increase contractility, heart rate, as well as jumpstart the renin angiotensin aldosterone system. Whereas Beta-2 adrenergic receptor's play a role in vasodilation of blood Vessel's or smooth muscle with in the G.I. tract or respiratory tract, etc. *****Also yes I did make a mistake I should've said beta-2 receptors on the bronchial smooth muscle. That is my mistake*******!!! We plan on making a video focusing more on the sympathetic nervous system and it's receptors within the next week or two.
Thank you very much for the really great video! I would like to ask about the part at 23:10 where you mentioned that our blood vessels to the kidney and tissue constrict in order to inhibit their activities. But in 21:21, vasoconstriction causes the blood pressure to increase. So in that case, isn't constricting the blood vessels to the kidney and skin actually increasing the blood pressure thus leading to increased activity of those organs? That means more blood supply are going to the kidney and skin right?
the activity of kidney is more related to how much blood is going there because of hidrostatic pressure that causes filtrat to develop. actually pressure of blood isn’t that significant
21:18doesnt vasoconstriction causes less blood supply..since due to lower diameter causes lower blood supply..if u could plz describe how blood pressure helps to cope up with vasoconstriction..
I never got why everybody is speaking about BP when it is perfusion that matters... The blood is indeed redistributed during acute stress reaction, but how overall increase in resistance helps to increase perfusion? Is it because of increased velocity of blood - that the blood doesn´t spend time in larger vessels and goes more quickly from the heart to tissues and backwards?
love ur lecturers always make me laugh at some point 😋mmm love pizza ，cooper cheese， milk ...never mentioned if u love broccoli or any type of veggies😅thnx a lot for all ur amazing lecturers I am addicted to ur channel✌
NT that release to stimulate Chrommafin cell is Acetylcholine not NE right? If it’s like that, so before it stimulates chrommafin cell, does NE participate in the journey as the NT or not?
Imagine if there were teachers that were this good on all subjects on this platform
Do you have love button instead of like? I love your lectures.
😂🤣😂🤣👍👍
Noooiiiceeeee 👍😂
Lame
hahah wow
This comment deserves more likes.. I'm sure we all think the same
I cant thank you enough. If there is an award for best teacher for medicine in youtube. It goes to you my friend.
hahaha I support your idea
Catecholamines
Stimulus-
Acute stress
Target organs-
Liver, heart, adipose, blood vessels, lungs, GIT
Actions-
Increase glucose level, increase BP
Little detail at the end; I believe it’s Beta 2 adrenergic receptors associated with dilation of the bronchioles! Not Alpha 2! Thanks to your video on adrenergic receptors, in your neurology playlist, I was able to learn about these receptors! Thank you for all of your amazing videos!
just wanted to type it when i heard it
Wooooow no words to say what a knowledge u remember everything ur a real ninja🦅🤺
Ninja I really like your passion talking and teaching about this stuff.. you had me at cortisol.. but when you looked at the camera and said "Glycerol.. BEAUTIFUL" lmao.. I really enjoyed your lecture.. I learned a lot and am a new subscriber.
Taking pharmacology at med school is hard but your videos make it much more easier to understand the concept. thankyou very much. Appreciate it.
omg!omg!omg!... this is soo good.... i know medicine is beautiful... connecting everything is way beautiful.... and the way you doo it , just amazing!...u r teaching us taking the body as a whole..... thank soo much for these wonderful videos!!!
Epic lecture. You have set a solid stage for us to explore downstream effects of this cascade.
Everybody: chased by Lion
This awesome dude: orangutan
orangutans are quite gentle actually. unlike chimpanzees.
Makes me want to watch the Clint Eastwood movie "Every which way but loose"
@@PriyabrataHalder He's a PA, not Jane Goodall lol
I have no idea what have i done without ur videoss fr
Hello there! You are awesome! When I tried to read the books about this topic, I can’t understand the concept. Just by watching his lecture, I was able to say ‘that’s easy to understand’! Now every time I have to read some medical information topic, I have to watch his lectures first then read the book. It makes my life easier😊
What do you do ? Do you read books related to medicine to get information or you are a medical student? No offense I'm just curious!
@@radi00_ I’m a nursing student.
Sometimes, thinking, visual picture and hearing can also stimulate hypothalamus to send down action potentials and stimulate thoracolumbar outflow.
Thanks for putting so much efforts of making those videos, you really really help us! you have a unreal talent of explaining and teaching!
thank you for sticking through the whole process of making this video
I love you you tought me more than all my teachers combined, thank you!
you made is so clear for me, cant express how thankful im .
Chrommafin cells in adrenal medulla have lost axons and dendrites.They are only post ganglionic cell bodies.
Exactly 👌🏼
You are amazing dude i wish you continue your work and develop yourself to better and better
i am a ninja nerd addict.however if i am not wrong, i think it is not Alpha2 receptor but the Beta2 receptor that cause broncodilation as against what you have mentioned almost at the end of this video(at 24.50)
abdul rahman you are correct.
correct its the Beta2 receptor
22:24 is the best part of the video!
I've always avoided your videos because they were super long and i have little time but wow, you answered all the questions i had on this particular topic.Thank you
U the best.... Can't thank you enough... U save our time before the exams....God bless u ...💯
What a simplification in a professional form? Wow really amazing,Go on !
I don’t have words to comment about your videos…every topic.s are clear cut..thanks a lot..please make videos about other medicine subspecilities too
Your way of teaching is extraordinary and very helpful to millions of medical students and professionals all over the world.You may like to correct the last point where you said Alpha-2 in the bronchial smooth muscle to Beta-2.I really admire you and hopefully one day we will meet in person.
you are amazing ....you actually deserve each and every like from the viewers.
No word can describ how am grearful to you thanx from my Heart you are the best💙💙
I love watching this stuff (and I'm doing so purely out of curiousity, because I have no qualifications in any of this, but the more I watch & read - the more it makes sense) It is "beautiful".
no words enough to thank you 💙
Sir chromaffin cells don't have axons they are actually post ganglionic cell bodies, and Beta 2 receptors are present on bronchial smooth muscles not alpha 2
Sir Thanks for giving this kind of quality education love from Pakistan
This is one of my favourites because it encompasses many other systems. Thank you!!
NinjaSir: You don't wanna pee on the orangutan
Darn it! My plans! 🤣🤣🤣
You have an absolutely perfect explanation
It's Mbbs level lecturer very helpful...I loving it.❤️❤️❤️
You are such an amazing Teacher. Lots of Respect and Love.
Omg this is amazing I love how you explain things man you're great I really enjoy it so much thank you so much btw it's 2020🤓
best teacher ever
I can't believe I didn't find your channel sooner!!! I actually get it now!!!!
Small complaint: Please add subtitles! Seeing the words helps me comprehend better ^-^
Please keep making more videos , YOU are gifted !
Here is ur award sir 🏆
Bravooooooi
love your lectures! you are genius!
It is excellent way of teaching.
Thankyou very much sir beautifully and easily explained
This was awesome, thank you. Only note is that the main receptors responsible for vasoconstriction, increase HR and BP are the BETA-1 adrenergic receptors (not alpha-1)... and bronchodilation are BETA-2 Adrenergic receptors (not alpha-2).
+Kayla Akemi As for your comment alpha-1 adrenergic receptor's do play in important role in constricting blood vessels which would cause the increase in peripheral resistance and therefore an increase in blood pressure. Also by constricting certain blood vessels we can divert that blood to the more vital organs. The beta-1 adrenergic receptor's are generally only present on the myocardium of the heart as well as the Juxtaglomerular cells in the kidney this allows for us to increase contractility, heart rate, as well as jumpstart the renin angiotensin aldosterone system. Whereas Beta-2 adrenergic receptor's play a role in vasodilation of blood Vessel's or smooth muscle with in the G.I. tract or respiratory tract, etc. *****Also yes I did make a mistake I should've said beta-2 receptors on the bronchial smooth muscle. That is my mistake*******!!! We plan on making a video focusing more on the sympathetic nervous system and it's receptors within the next week or two.
Sir u make me speechless lub u so much ❤️❤️❤️
Thank you guys, my scores in Uworld are increasing bc of your lectures🥰😘
Thanks .u r really a good teacher..learn a lot
Thanks for the beautiful lecture but bronchi have beta 2 receptor for bronchodilation
what a great teacher !
you are awesome💗😍
Thank you very much ! I found these videos so helpful !
+Inspiration Elham that's awesome I'm so glad they are helpful!
Thank you! I enjoyed your lectures!
You don't wanna pee on the orangutan...got me wheezing 😂😂😂
absolutely awesome !,thank you
Professor Ninja, good job
the bestest!! thank you for everything
Very important ,easy to understand ,
Tnx
Ek number sir amazing
Thank you very much for the really great video! I would like to ask about the part at 23:10 where you mentioned that our blood vessels to the kidney and tissue constrict in order to inhibit their activities. But in 21:21, vasoconstriction causes the blood pressure to increase. So in that case, isn't constricting the blood vessels to the kidney and skin actually increasing the blood pressure thus leading to increased activity of those organs? That means more blood supply are going to the kidney and skin right?
the activity of kidney is more related to how much blood is going there because of hidrostatic pressure that causes filtrat to develop. actually pressure of blood isn’t that significant
More volume more filtrate so on vasoconstriction blood volume decreases,filtrate decreases,urine output decreases
great explanation . thanks a lot .
Excellent i am a fan of your educational videos
21:18doesnt vasoconstriction causes less blood supply..since due to lower diameter causes lower blood supply..if u could plz describe how blood pressure helps to cope up with vasoconstriction..
Lower diameter of the blood vessel causes blood pressure to rise and that increases the rate of glucose consumed by the tissues.
Thanks a lot Zach
You have really helo me , thanks
This was great, didn´t understand one word but still...
23:11 "you don't wanna pee on the orang outang" 😂😂😂😂
What is the use of pKA in this particular scienerio, all the actions are mostly done by the cortisol for gluconeogenesis,
What an explanation ♾♥️
..."...what else can this liver do, this beautiful liver..."...
Excellent lecture guy
Thanks a lot sir!
Ohhhh...god ,i love it
Thank you so much for this amazing video 🌹🌹🌹
Amazing , and very helpful
+amal abughneim Awesome!!! I'm so happy we were able to help!!
I never got why everybody is speaking about BP when it is perfusion that matters... The blood is indeed redistributed during acute stress reaction, but how overall increase in resistance helps to increase perfusion?
Is it because of increased velocity of blood - that the blood doesn´t spend time in larger vessels and goes more quickly from the heart to tissues and backwards?
love ur lecturers always make me laugh at some point 😋mmm love pizza ，cooper cheese， milk ...never mentioned if u love broccoli or any type of veggies😅thnx a lot for all ur amazing lecturers I am addicted to ur channel✌
Please is there a video where the synthesis of epinephrine from tyrosine is explained?
Love from India🇮🇳
So cortisol and adrenaline are almost the same at intermediary metabolism?
Du bist der Beste!
loving as always!!!!
man Istg u r THE BEST
NT that release to stimulate Chrommafin cell is Acetylcholine not NE right? If it’s like that, so before it stimulates chrommafin cell, does NE participate in the journey as the NT or not?
Hats off to u😍😍😍😍
Wonderful work once again, Thanks
Hi sir i have a small confusion on 24.53, , i thing lungs have BETA2 receptor.. not alpha 2... please clear this... please
Another brilliant video...
LIFE SAVER
wonderful!! Loved it
I loved , thx❤🎉
Thank you this is really helpfull, and very clear!
Love u man❤️❤️
My hero❤
Amazing videos can’t thank u enough
I think beta 2 action what causes bronchodilation.
You are my cardiac as always.
Sir, I love ur video.. can you suggest me which book do you follow for this chapter?
Thank you sir
'thats the best' 22:31
LOVE LOVE LOVE!!