Don’t worry about not knowing about the Basophil, the reason it’s depicted as a ninja that talks in a cryptic fashion is because it’s not entirely clear what they are for.
i think it might also be a kind of reference to hataraku onii-san since the koala character the voice actor voiced in it spoke very similar to how basophil talks
I think the parasite shown in this episode is a Japanese one. You see medical education in terms of diseases is slightly different in different regions or countries depending upon the types of diseases that affect said countries. A Japanese doctor might have recognised the parasite considering how much raw fish is consumed in Japan.
@@EspeonMistress00 nope its just because he's not used to see sea based bacteria maybe he's more into land. People that lives near high amount of salt water have heard of them once in a while.
Just wait! One day, you'll get a patient with this specific food poisoning, you'll be able to identify it, and when your colleagues ask you how you know it; you'll look them straight in the eye and say "I saw it on an anime."
I just did some calculations and found out that the "Cells at Work" series actually makes up for more than half of this channels views at 50.2%. It also helps that your videos have gained traction in Japan as well. Because of your medical knowledge and that you unknowingly predict events in the anime they call you 「野生のネタバレ」or "The Rogue Spoiler".
@@completem3ss I just added the number of views of the Cells at Work videos and the total views of Dr. Hope's channel. Then calculated how much those views make up of the total views.
There is a spin off series to this one, 'Cells at Work BLACK', which is far more intense. It shows the cells functioning in an unhealthy body (stress, smoking, alcohol, obesity etc...) and honestly it's scary to see. The body is in such a poor state and the cells have to struggle so hard just to keep things running in what feels like a constant warzone. I've known people who've started avoiding fatty foods and alcohol because of what they learned in Cells at Work Black. I hope that after the core series is complete they will animate the Black spin off, the world needs to see it.
If they do make a series out of it, I don't think it'll be as freely broadcast as the original 😂 Especially because of the... disease... and dysfunction. 🤣
Hi, Japanese med student here! Enteritis Vibrio's scientific name is Vibrio parahaemolyticus. It's a common germ that causes food poisoning in Japan as it's contained in row fish and row fish is commonly eaten in Japan. I suppose it's not as common in Europe!
Hello Doctor Hope! I am a Japanese audience. Thank you for uploading the video. Anisakis is a famous parasite among Japanese who often eat fish raw. The other day my friend 's boss was infected with Anisakis... So I was surprised that you doctor were not familiar with Anisakis and Vibrio enteritis. It is interesting that popular diseases and parasites differ depending on the country and culture. I am looking forward to your videos! I'm rooting you from Japan :)
it's in fact a geographic/cultural thing. Here at Americas (USA, Mexico, Latinamérica) anisakis infection it's pretty uncommon because we don't use to eat raw or almost raw seafood (of course there are exceptions, like in México certain tipe of oisters and the Ceviche here and at Perú) We are very more familiarized with red meat infections, like cisticercos, from the pig meat, or the free live amoeba, from the raw greens and fruits.
Idk why i dont get ads that much, i saw the yellow thing, but it didn't give me an ad? I know this premium youtube thing, but i don't have it, but im free from ads? When i saw your comment, i was waiting for the ad to happen, but nope no ads.
I'm a med tech, and if you ever did a wright stain on a blood smear, the granules of a Eosinophil will be bright pink while in Basophils they'll be dark blue, hence the color of their outfits~
@@SonTran-vb8xt Indeed and this one was probably a fairly recently hatched one at that scale, parasitic worms can get pretty gigantic. Scaling up something like a mature tapeworm from the scale of a 15μm neutrophil to a 1.5m human and you have a beast with a head around 100 meters long and a body that could extend into the thousands of kilometers. The longest ever removed was like 25 meters long with the same 100,000 scaling factor this beast would extend pretty much perfectly from London to Moscow or just short of the distance from New York to Denver. So I would say this one in the episode must have been a recently hatched one though this makes sense the food was probably contaminated with just eggs or small lavae not the adult worm. An adult parasitic worm if we were on the same scale as these cells would be big enough to devour something the size of the empire state building like we eat a grape just bite the whole thing in one go.
Hey Dr. Hope, not sure if you'll see this, but I'm a Nurse from Canada. I stumbled upon your Cells at Work series recently and have been binge-watching you since. Being both an Anime fan and healthcare professional, I really enjoy your videos. You make learning about the medical world both informative and engaging. I can tell you're very passionate about the profession and community and I'm so glad to have found your channel. Keep on keepin' on!
Probably, Yes. Of course there are lots of raw fish dishes in Japan besides sushi, so that person may have eaten them. I heard that sushi is in fashion, so it may not be rare in the UK.
I watched this with my mom, who works in a hospital laboratory (sees a lot of pathogens/infections)... she said she's heard of anisakis but never seen it. So from that I took it is quite rare in North America (and probably Europe too).
@@tofu_golem The key here is that the British don't eat much raw seafood in comparison to the Japanese, so therefore do not expose themselves to as many parasites.
@@mika-tu6ld Little bit of culinary trivia for non-Japanese that becomes kinda important in context of the show/this comment: *"Sushi" does not actually refer to "raw seafood" dishes*; in Japanese cuisine, it refers, instead, *to the rice preparation it's served with* (if you're wondering what makes it a sushi preparation: sushi rice is made with a - IIRC sort of sweet? - vinegar, and cooked so that it sticks to itself, making it easier to form into shapes). Seafood, including raw seafood, is COMMON in sushi dishes in Japan... but it's NOT required or even universal in "sushi" dishes; only the rice is. You could, literally, have a fried chicken sushi roll and so long as it included the rice prepared that way, it's still sushi (albeit very "fusion cuisine" style sushi). That said, the Japanese are still WAY more accepting of consuming raw seafood than most Westerners, yes. But (importantly for interpreting this episode!) given the actual definition, this goes beyond actual "sushi" dishes! "Sashimi", for instance, isn't "sushi" because it doesn't include the rice (though yes, it's often conflated with it in the English speaking world, because a lot of sushi places *also* sell sashimi). I don't know if other meats can be used in sashimi because I'm not entirely sure on what defines it the way I am with "sushi" - but I know that I've only ever seen fish sashimi listed on menus...and it's...basically a slice of raw fish in that case. Like, say, a slice of raw tuna or raw salmon. So tldr: If we're being technical (which I am I guess) *it could just as easily be a poorly-prepped and BADLY chosen piece of sashimi*. Or! probably some other dishes I'm less versed in the names of - I know there's a weird octopus dish for instance that's become a thing in at least one restaurant in Japan, where they *have* to serve it raw (and extremely fresh) because the selling point is, kid you not, that if you pour soy sauce on it it wriggles around like it's alive again, which they can only do *because* it's fresh AND uncooked (something about nerve endings and salt? idk man it's kinda cool but?? gross and weird to me?? so I didn't stick around to learn more from that video lol). PS: part of the reason I bothered to note all this? A lot of English speakers aren't aware of the actual definition of "sushi". A lot of us think it's ALL raw fish of some sort. But I want people to know it's not, because if the idea of "raw seafood" (understandably) grosses you out or makes you wary, and a friend wants to treat you to "sushi"? You don't have to turn them down! Just ask for sushi dishes where all the seafood is *cooked* (such as California rolls, which use cooked crab or imitation crab meat), or, ask for "vegetarian" options that don't have seafood at all. :)
tbh the way you showed off the different cells at 4:52 and also cutting in the images from the different episodes where they were first shown is a really nice editing job. I enjoy this series a lot and stuff like that shouldn't get unnoticed, its awesome.
Quick little update: Because of this show and this channel, I am getting an A in my Bio class. Now, if only there could be an anime series about Calculus...
Aw man, I remember watching this and thinking "I wish someone would explain everything that's going on here and what the cells are really doing." (Google seems to think that if you know a cell name you must be fluent in medical science.) Thanks for making it come true!
Eosinophiles appear slightly orange-pink when you see them under the microscope 👍(pappenheim colouring) I am a Medical Lab Technician and i love those litte details! :D
I have Idiopathic Urtucaria and my basophil level is over 4 times the normal (0.5% of TBC) level - I like to think my blood's full of cryptic ninjas who have no idea what they're doing.
@@cactaceae378 Sadly not an option, unless science finds a cure in the future ;) But I'm actually more optimistic considering how fast A.I. is improving. Or CRISPR, if you've heard of that. But I also have the usual autumn infection at the moment, so that should get better soon ;)
This was one of my favorite episodes. I'm not a big biology nerd, but the biggest "awwwww sheeet" moment was when the Anisakis showed up, and I realized that Eosinophil was carrying... a harpoon.
I believe the reason why you are not super familiar with the bacterium in this episode might be because the Japanese people eat a lot of raw seafood and this type of seafood poisoning is much more common in Japan than elsewhere. Still, it's always interesting to see how culture and life style can effect which diseases are commonly observed in your community (I'm sure there are also lots of diseases commmon in Europe that Japanese doctors aren't familiar with as well).
If you have a good teacher it is. However, the medicsl field tends to be picky about whom to accept in. Plus, working with patients isn't for everyone (it sure ain't for me)
This was a fantastic analysis. I very much enjoy watching these, not just for reactions, but being able to learn from a charismatic doctor who is willing (and eager) to break things down into layman's terms. Thank you for doing these!
Culinary major here, and this poor guy probably ate MULTIPLE infected foods, since the vibrios are more associated with contaminated oysters, and anisakis simplex is mostly found in raw fish, at least according to my food safety notes. Anyways, this is why we don't buy back-alley sushi. Because worms.
When I was travelling in Japan, I tried out some conveyor belt sushi. And for the first time I got to try various raw fish aside from salmon and tuna. At the same night, I could feel my stomach rumbling in discomfort. Not that painful to be alarmed, but, I'd imagine this very episode could be playing in my stomach.
I really like his humbleness in his learning attitude towards something he doesn't know. I also admire that he says it portrays things in a "different way" when he sees that the pathogen eats up the WBC. He could've attacked the anime by saying "oh it's so wrong" but he did not. He has such a nice, respectful personality which we want in all doctors. Thank you for the great review!
Vibrio Enteritis is one of the common infections here to those that eat contaminated seafood (or at least around SEA where I live), so the name pops up pretty often when talking about food poisoning, especially among those that love to eat seafoods @@
In fact, in the Spanish subtitles they translate it as Vibrio parahaemolyticus, a gram-negative, mobile bacterium that does not have a capsule or spore, as well as tolerating common salt, which is why it develops in seawater and can grow at pH 9 in slightly basic media, which explains the infection caused after eating seafood :)
Jc Arroyo I don’t see why you can’t put a knife through a lobster’s or crayfish’s head and then immediately throw it in the pot. I’ve never gotten sick.
@@cats140197 So here's the thing. I went and looked up that species of Vibrio and according to the site: www.health.state.mn.us/divs/idepc/diseases/vibrio/basics.html and the subsequent image on Google: www.ehagroup.com/assets/img/site/pathogens/pathogen-vibrio-parahemolyitcus.jpg It seems the images would add up that this person would in fact have this species of Vibrio bacteria, given the fact the miniature strands of Vibrio resemble the structure of the Google image. However, the site says you normally get that sort of infection from shellfish and oysters and is found in the US and Canada coast as well. Symptoms usually happen 24 hours after eating contaminated food. Anisakisis on the other hand, or "Herring Worm Disease" can only occur if the host eats nematode egg infested raw fish or squid. www.cdc.gov/parasites/anisakiasis/faqs.html#what Symptoms of course do include vomiting, abdominal pain, diarrhoea, etc, but what isn't said is that the nematodes not only burrow in the tissue, they tend to die when they reach the human body. If caught in the mouth or esophagus, the hoost can cough up the worms or pull it out of the mouth. If it's in the stomach, it's usually vomited up to expel the worm out. Remember when Eosinophil-san killed the nematode, and the stomach erupted as soon as it fell into the stomach acid? the body naturally induced vomiting to expel the foreign substance again. So in this episode, not only do we know the host body ate either raw fish (sashimi) or raw squid, but it probably ate infected oysters or shellfish too. Probably went to a local sea-based restauraunt and the food quality was sub-par. We know that person won't make that mistake again for sure!
Don't worry Doctor, i get goosebumps too during the fighting scenes. This anime helps me to take better care of myself because all these cells are trying to keep me alive, the least i could do is make their job easier. I be like patting a random part of my body and say "Good job you guys" whenever i watched an episode xD
In my case, my platelets are apparently trying to kill me, since I have Thrombophilia, but I still can relate myself to your new sense of self-care. I went to a Nutritionist soon after I watched the series, so I could help my good bois and gals inside me in good shape :)
Tbh tho. I take care of myself because I think of that romance of my cells I CANT HELP IT THEYRE GONNA DIE IN A SHORT AMOUNT OF TIME WHY WOULD I SHORTEN IT??
Thank you for reacting this anime! I’m a japanese nursing student and I really love your reaction and classes😆 I can’t wait your next reaction! Thank you again! BTW I’ve seen Anisakis in a raw oyster before...
Vibrio is a genus of "Gram-negative bacteria" that belongs to the order of Vibrionales, which is an order probably most well-known for causing Cholera. I don't know if Cholera is a well-known illness in Europe, but here in the US it caused a scare a few years back, so that is why I used it as an example.
Stefan M. I’m not sure if cholera is still that much present but iirc there was outbreak of cholera in Europe before America was even discovered so Yeah we at least know it by name
Heads up (NOT a spoiler), in later episodes, the subtitles say "antigen" and "heatstroke" in some areas. Just know that if in some of the areas where such terms are technically incorrect, it was the fault of the person in charge of the subtitles, the Japanese terms used are actually the correct ones. (informed by someone else who knows Japanese far more than I do)
I love, love, love the way you use your words to paint the picture of what goes on inside our bodies. For the majority of us, we will never see the inside of our body and yet we can through your words...great job! Love your channel!
Earlier this year I had to get my esophagus stretched. I’d been having trouble swallowing and had two serious choking incidents because of it. The doctor took a biopsy during the procedure and when I woke up he told me I have “Eosinophilic Esophagitis”. I think he was surprised at my response. “Eosinophilic? As in Eosinophils? They’re immune cells right? So it’s some type of allergic reaction?” I’m no med student....got that all from Cells at Work!
Just started watching cells at work because of your reaction videos. So my routine becomes watching the episode then going in here for the explanation so I can understand it clearer.
Teacher: Are you alright? If you aren't feeling well go to the infirmary Me: ugh, at this rate, the sea of hellfire will open the forbidden door! Teacher: Nani!? *Proceed to give me a bag of plastic to throw up*
Your commentary is so wonderful. It's calming to hear, yet informative to where even someone like me, without any medical expertise can completely enjoy it. Thank you so much and I love this series of yours~
I am not a medical student, but I studied a lot of human biology, and I believe that the reason we didn't study some of these pathogens is because the Anime is directed to Japanese audience so it is logical that they explain to their children about the local diseases given that the Japanese diet is mostly seafood. Just another great perspective from the producers of this show
Its nort really the seafood itselfs it how they prepare it. The UK eats a a lot of fish but we tend too cook it, where as in japan its more common for it to be eaten raw and thats why we get diffrences in bacteria/viruses
From Japan I enjoy watching your video. I use too poor English to describe my enough Impression. but it's very very very fun and cooooool! I love your videos. Good luck!
Basophils in general are not well understood. We know they're an immune cell, and that they participate in the immune reaction, but we're not entirely sure what they do, which is why the author made Basophil always speak in riddles and seem mysterious. Another neat easter egg in this episode is if you look at Eosinophil's hat, it looks just like the drawing of the Eosinophil because of the two-lobed nucleus. Same thing with Basophil, if you turn the drawing upside-down it looks like a mask, which fits even better with the mysterious vibe they were going for.
It's not just that Basophil speaks entirely in cryptic metaphor, it's also that so far only his fellow granulocytes like U-1146, Eosinophil, and Mast Cell have been able to vaguely understand the point he is making. Every other cell type in earshot of him has no idea what he's babbling about until a granulocyte translates him aloud.
The bacteria comes from contaminated seaFOOD, not seawater, and when 'it' eats our friendly white blood cell, it's because it's a "colony"! It absorbs him/surrounds him, I guess. I suspect we'll see him fight his way out later. Edit: Yeah, he busted right out of there. Love the show, keep up the good work!😊
@@MichaelBerthelsen Ah, Yeah, at around 6:40 you see the "underlings". Then I took a good look at the "big guy" and now it's obvious that's just many of those individuals together. That's cool that the detail is there, but I'm surprised they didn't point it out in the show. They even made it so subtle that Dr. Hope didn't pick up on it. The percent of the audience who actually caught this reference seems too small.
MedTech/MLS student here and I swear to God this show has vastly improved my WBC counting times something about ascribing character traits to the cells helps me recognize them faster. You seem to be having a lot of fun with this show doc! Can’t wait for you to see (and probably squee at) some of the less commonly known, more obscure stuff this show throws at its audience.
@@michael22000 well the whole "twist" of the arc is bluntly advertised as log as you have some understanding of the workings of you body so I didn't thought this would qualify as a spoiler
That's just my opinion tho By saying. Can't wait you review the "topics" episode in episode 6 and 7. Now I have a piece of information about episode 6 and 7, and I will be expecting it to happen. Not that I can just erase what i saw tho. But it's not really a problem for me, it's just kinda annoying that I just saw that while scrolling down the comments. So i put down a comment. :) But you already corrected it, so it doesn't matter anymore hehe.
I love watching a well made anime with someone who is actually an expert in that field - it's such an enriching experience. Whether it's Haikyu with a volleyball player or Cells at Work with a doctor. Thank you so much for taking the time to share your knowledge with us all.
I'm so impressed with the tools you used to explain the knowledge. Now I know the neutrophils are not big enough to fight with parasites (from your drawing) and how eosinophils fight and how basophils works (the cubes you use as chemical substances). Originally I think episode 4 anime is not as interesting as previous three episodes due to less information I can get from this chapter. Your video just compensate this and makes me like this episode more & more than before. Amazing!
I'm currently a high school student and I've always admired people who can just talk about stuff on the top of their head. I wanted to be a doctor when I was younger but then found myself hating biology when I just entered high school, so now instead I'm focusing more on physics and chemistry. But for some reason I just find this series very entertaining to watch(although I have absolutely no idea what you are talking about when you explain stuff). I think it's just because that seeing a real doctor explaining stuff reminds me of what I thought doctors do when I was younger... Anyways please continue the series, I absolutely love it!
@@Chemeleon15 again with that thing? How does that remind you of a sickle cell even if you (I assume) have seen many, *many* ahoges in anime/manga? How uneducated are you? Or just how new to anime/manga are you? Geesh I'm salty. It's been months now and people still think she a sickled cell.
This is actually super interesting because Sushi isn't nearly as common in the West as it is in Japan, and since Sushi is more-or-less raw seafood it makes sense that they'd be more familiar with pathogens and parasites related to uncooked seafood while the same things are way more rare in other countries. So while Dr. Hope didn't know what it is, a Japanese doctor would probably be like "Yeah, I know this thing, it's this organism! I've heard of people getting that." Always cool to see the effects of different cultures like this.
dracocrusher Anisakis and Vibrios are actually really present inside western seafood as well, but there is a huge difference when it comes to preparation. During import and fishing, the quick freezing of fish and seafood manage to make pathogens " fall asleep", so that they can be digested with no problems. Before preparing Sushi, restaurants must keep the food frozen for at least Two days! In Japan, fish is bought the same morning at the market and there you have it, a bigger chance to get parasytes! ...Heh, sometimes fresh fish is far more dangerous, Who would have thought!
Lovely explanation and review once more, doctor-sensei. Medical student here, I really appreciate how you expound on an already wonderful show. Keep up your good work and also this service for the people not in the medical field. ❤
Thank you for this very interesting and entertaining series. Love the cute and easy to understand drawing. The spring like bacteria at the start should be Helicobacter pylori. This bacteria looks like a spring and is able to attach to stomach. "Fun" fact it's the only bacteria known to directly cause stomach cancer. The strange coton like bacteria is a "cousin" of the vibrio cholerae. Both can live in normal and salty (sea) water and give very aggresive diarrhea, especially if you are in vacation without boiling water. I like the way the show treat the eosinophils and the basophils. The old way to identify them was to used red (eosin) and basic/blue (methylene blue) dyes, giving a red color to eosinophils and blue to basophils. Moreover they are very rare (
There is an individual chapter about Helicobacter pylori in the original manga, however it is not as same as this one. The Helicobacter pylori design in this series is much more bigger and scarier, and it can cause stomach cancer. Usually it keeps staying in the stomach because it can live with the gastric acid without getting destroyed
Another great episode! Interesting to note, when examining these cells under a microscope, eosinophils will uptake pink dye and the basophils will uptake blue dye - another interesting detail added to their designs (Eos' pink jumpsuit and Baso's blue headband)
Just a little info from a doctor working in Southeast Asia. Anisakis is actually a type of roundworm. I don't think I've ever seen a case of Anisakis penetrating the gastric lining. Could be a rare occurrence I'm not aware of, since these roundworms usually just produce mild symptoms, most often in Japan, where they consume raw fish. Anisakis infections are usually treated symptomatically, since humans are dead-end hosts to these particular parasites.
I love cells at work, because as someone who has nothing to do with the medical community (yay film major), I'm also just fascinated with the human body and microbiology in general. I absolutely love your reviews, because not only do I get to watch someone watch this show I love for the first time, I learn so much from it. It's so wonderful to learn from someone who loves what they do, and is falling in love with this show I adore. These videos are always a highlight to my day, thank you! I can't wait until the next one.
"I always get goose pimples" You get w h a t I prefer goose bumps omg Love the videos though!! I loved this anime and having you review it and make comments to teach your viewers has helped me enjoy the show more. It's so cool having you explain something and then being able to connect it with something else I've noticed in the show. Keep up the great work!!
Don’t worry about not knowing about the Basophil, the reason it’s depicted as a ninja that talks in a cryptic fashion is because it’s not entirely clear what they are for.
AnimeOtaku2 they say that in the episode......
RiorXD I noticed.
AnimeOtaku2 guess some people just like to feel included.
The Basophil doesn't even know what it is doing
i think it might also be a kind of reference to hataraku onii-san since the koala character the voice actor voiced in it spoke very similar to how basophil talks
*doctor learns from anime*
LADIES AND GENTLEMEN...
*WE GOTTEM*
I think the parasite shown in this episode is a Japanese one. You see medical education in terms of diseases is slightly different in different regions or countries depending upon the types of diseases that affect said countries. A Japanese doctor might have recognised the parasite considering how much raw fish is consumed in Japan.
* applauds *
@@EspeonMistress00 nope its just because he's not used to see sea based bacteria maybe he's more into land. People that lives near high amount of salt water have heard of them once in a while.
@@saberruntv I didn't talk about the bacteria I said *parasitie*.
some diseases are common in some countries but not known in other
Just wait!
One day, you'll get a patient with this specific food poisoning, you'll be able to identify it, and when your colleagues ask you how you know it; you'll look them straight in the eye and say "I saw it on an anime."
Katie Leffler I can imagine that and I'm just laughing so much 😂😂
Aditya Valvi / Adi 😂 Mark his words! LOLOL
Love your comment ...lol
Dosent mean you know it
Omg !! I'm dead 😂😂😂
I just did some calculations and found out that the "Cells at Work" series actually makes up for more than half of this channels views at 50.2%. It also helps that your videos have gained traction in Japan as well. Because of your medical knowledge and that you unknowingly predict events in the anime they call you 「野生のネタバレ」or "The Rogue Spoiler".
XD What the heck
Where did you know about this? 😂
@@completem3ss I just added the number of views of the Cells at Work videos and the total views of Dr. Hope's channel. Then calculated how much those views make up of the total views.
百合歓迎会 *_QUICK MATH!_*
...it also helps that Dr. Hope is so cute and charmingly befuddled 😅...
There is a spin off series to this one, 'Cells at Work BLACK', which is far more intense. It shows the cells functioning in an unhealthy body (stress, smoking, alcohol, obesity etc...) and honestly it's scary to see. The body is in such a poor state and the cells have to struggle so hard just to keep things running in what feels like a constant warzone.
I've known people who've started avoiding fatty foods and alcohol because of what they learned in Cells at Work Black. I hope that after the core series is complete they will animate the Black spin off, the world needs to see it.
Yas gawd
Oh I'm going to go check it out. If they decide to make an anime out of it, that'd be great, but I enjoy manga just as much as anime.
Mikazuchi I scared my friend’s kids into a healthy lifestyle using that manga lol 😂
If they do make a series out of it, I don't think it'll be as freely broadcast as the original 😂 Especially because of the... disease... and dysfunction. 🤣
Another series of this?! 😲😲😲I gotta search that!
This should be titled, Successful doctor becomes the ultimate anime fan.
This should be titled "The Great Doctor Joins Elon-chan Into Weebdom" as great men alike share great tastes
@@dandanthedandan7558 Lmfao
*ahem* Hope-chan
imagine if he watched something like Black Jack and it would be uncomfortably weird as hell because none of the surgeries actually make any sense.
@@artemisflow6658 it is still fun to see cancer fall in love with an edgelord
“Obviously they put an ad break now”
-immediately cuts to an ad-
Outstanding move
Hayden Laver indeed
Same on my end
Same! I got 2 ads
I got an ad immediately when he said that
I think the video is claimed
"A sea of hellfire that open the forbidden door."
Taco Tuesdays in a nutshell.
Which door? The back or front?
@@Penguien001 back
@@Penguien001 Yes
Me: 🖕
@@zhipeizhou5582 The middle. Yes
Hi, Japanese med student here!
Enteritis Vibrio's scientific name is Vibrio parahaemolyticus. It's a common germ that causes food poisoning in Japan as it's contained in row fish and row fish is commonly eaten in Japan. I suppose it's not as common in Europe!
魚を生食する文化の日本と、それはもうめちゃくちゃ火を通すイギリスとでは、メジャーな食中毒とかも違うんでしょうね。興味深い！
So basically this body ate some very poorly prepared sushi
Yep
@Daniel Dong A man in anime ate a raw seafood, this is what happened to his immune system
Could be any poorly cooked fish rly
sushi? :V maybe not. but a bad cooked fish
Well, poorly kept.
Hello Doctor Hope! I am a Japanese audience. Thank you for uploading the video.
Anisakis is a famous parasite among Japanese who often eat fish raw. The other day my friend 's boss was infected with Anisakis...
So I was surprised that you doctor were not familiar with Anisakis and Vibrio enteritis. It is interesting that popular diseases and parasites differ depending on the country and culture.
I am looking forward to your videos! I'm rooting you from Japan :)
it's in fact a geographic/cultural thing. Here at Americas (USA, Mexico, Latinamérica) anisakis infection it's pretty uncommon because we don't use to eat raw or almost raw seafood (of course there are exceptions, like in México certain tipe of oisters and the Ceviche here and at Perú) We are very more familiarized with red meat infections, like cisticercos, from the pig meat, or the free live amoeba, from the raw greens and fruits.
Electron Can you not
I thought that had been the case haha
@@Teapot72 Hey now. Just cuz he's an electron doesn't mean you gotta be so... *negative*
@Yuki Mishima へー、言われた人間はなにも思ってないとでも？
How dare you say such a thing?
Did you just put an adbreak just when the anime put one? Now that is coordination.
Yep.
and consideration
I said "I see what you did there" out loud when it happened.
Ikr
Idk why i dont get ads that much, i saw the yellow thing, but it didn't give me an ad? I know this premium youtube thing, but i don't have it, but im free from ads? When i saw your comment, i was waiting for the ad to happen, but nope no ads.
I'm a med tech, and if you ever did a wright stain on a blood smear, the granules of a Eosinophil will be bright pink while in Basophils they'll be dark blue, hence the color of their outfits~
And don't forget that Eosinophil's nucleus is a reference for her hairstyle.
Her pigtails. :3
The attention to detail is amazing! Love it. And I figured the hairstyle had a purpose as well.
Ohh a fellow med tech!
@@izzy_theog9658 OH YEAH! The lobes! Man, this show is clever!
@@KRISIS1451 basophil's hairstyle also represented his nucleus
Us: parasite = teeny little worm.
Cells at Work: parasite = a frickin’ KAIJU!
It is on a cellular scale.... And cells are even teeny-er then worms!
@@SonTran-vb8xt Indeed and this one was probably a fairly recently hatched one at that scale, parasitic worms can get pretty gigantic. Scaling up something like a mature tapeworm from the scale of a 15μm neutrophil to a 1.5m human and you have a beast with a head around 100 meters long and a body that could extend into the thousands of kilometers. The longest ever removed was like 25 meters long with the same 100,000 scaling factor this beast would extend pretty much perfectly from London to Moscow or just short of the distance from New York to Denver. So I would say this one in the episode must have been a recently hatched one though this makes sense the food was probably contaminated with just eggs or small lavae not the adult worm. An adult parasitic worm if we were on the same scale as these cells would be big enough to devour something the size of the empire state building like we eat a grape just bite the whole thing in one go.
If you didn't meet a kaiju, maybe you are the kaiju
Hey Dr. Hope, not sure if you'll see this, but I'm a Nurse from Canada. I stumbled upon your Cells at Work series recently and have been binge-watching you since. Being both an Anime fan and healthcare professional, I really enjoy your videos. You make learning about the medical world both informative and engaging. I can tell you're very passionate about the profession and community and I'm so glad to have found your channel. Keep on keepin' on!
Vibrio and Anixas are common pathogens of food poisoning in Japan that often eat raw fish.
Conclusion: the body ate some bad sushi
セイノツヨシ wow
Probably, Yes.
Of course there are lots of raw fish dishes in Japan besides sushi, so that person may have eaten them.
I heard that sushi is in fashion, so it may not be rare in the UK.
Since they got vibrio and anixas at the same time, they probably ate a plethora of bad sushi.
oppai
anime: (uses infections and parasites commonly found in raw seafood and japanese cuisine)
dr. hope, from england: what are these what
I watched this with my mom, who works in a hospital laboratory (sees a lot of pathogens/infections)... she said she's heard of anisakis but never seen it. So from that I took it is quite rare in North America (and probably Europe too).
That's funny because the UK is also an island nation. It's not like they are strangers to seafood.
@@tofu_golem The key here is that the British don't eat much raw seafood in comparison to the Japanese, so therefore do not expose themselves to as many parasites.
Paul T Sjordal we don’t eat raw seafood in the uk unless you make your own/buy sushi
@@mika-tu6ld Little bit of culinary trivia for non-Japanese that becomes kinda important in context of the show/this comment:
*"Sushi" does not actually refer to "raw seafood" dishes*; in Japanese cuisine, it refers, instead, *to the rice preparation it's served with* (if you're wondering what makes it a sushi preparation: sushi rice is made with a - IIRC sort of sweet? - vinegar, and cooked so that it sticks to itself, making it easier to form into shapes).
Seafood, including raw seafood, is COMMON in sushi dishes in Japan... but it's NOT required or even universal in "sushi" dishes; only the rice is. You could, literally, have a fried chicken sushi roll and so long as it included the rice prepared that way, it's still sushi (albeit very "fusion cuisine" style sushi).
That said, the Japanese are still WAY more accepting of consuming raw seafood than most Westerners, yes. But (importantly for interpreting this episode!) given the actual definition, this goes beyond actual "sushi" dishes!
"Sashimi", for instance, isn't "sushi" because it doesn't include the rice (though yes, it's often conflated with it in the English speaking world, because a lot of sushi places *also* sell sashimi). I don't know if other meats can be used in sashimi because I'm not entirely sure on what defines it the way I am with "sushi" - but I know that I've only ever seen fish sashimi listed on menus...and it's...basically a slice of raw fish in that case. Like, say, a slice of raw tuna or raw salmon.
So tldr: If we're being technical (which I am I guess) *it could just as easily be a poorly-prepped and BADLY chosen piece of sashimi*.
Or! probably some other dishes I'm less versed in the names of - I know there's a weird octopus dish for instance that's become a thing in at least one restaurant in Japan, where they *have* to serve it raw (and extremely fresh) because the selling point is, kid you not, that if you pour soy sauce on it it wriggles around like it's alive again, which they can only do *because* it's fresh AND uncooked (something about nerve endings and salt? idk man it's kinda cool but?? gross and weird to me?? so I didn't stick around to learn more from that video lol).
PS: part of the reason I bothered to note all this?
A lot of English speakers aren't aware of the actual definition of "sushi". A lot of us think it's ALL raw fish of some sort. But I want people to know it's not, because if the idea of "raw seafood" (understandably) grosses you out or makes you wary, and a friend wants to treat you to "sushi"? You don't have to turn them down! Just ask for sushi dishes where all the seafood is *cooked* (such as California rolls, which use cooked crab or imitation crab meat), or, ask for "vegetarian" options that don't have seafood at all. :)
Anime: Ad break plays.
Dr. Hope: Obviously they put an ad break here...
RUclips: Ad plays.
M E T A
Yeah after the doctor said it the youtube ad break play. lol.
I'm glad I wasn't the only one who laughed at that.
This was honestly one of the best placements for an ad I have ever seen.
tbh the way you showed off the different cells at 4:52 and also cutting in the images from the different episodes where they were first shown is a really nice editing job.
I enjoy this series a lot and stuff like that shouldn't get unnoticed, its awesome.
Lia vaca lola
Hope: *Gets to ad break in cells at work*
Hope: Of course they'd put an ad break he-
*youtube ad plays*
Coincidence? I THINK NOT
Syrus Alder me too
Haha game theory reference?
Ahahaha me too
Same
@@Random-yc2qg nope a film theory reference
Came for the anime, stayed for Dr. Hope. I love this! Lets get our food poison on... Okay maybe not the whole food poison thing
Quick little update: Because of this show and this channel, I am getting an A in my Bio class. Now, if only there could be an anime series about Calculus...
There's one about chemistry if that helps it's called Element Hunters. Kind of cheesy but it has an interesting twist using alternate dimensions.
Sexy anime numbers
Just Some Guy with a Mustache well there is that Calculus Rhapsody from 9 yrs ago that's been booming thanks to YT recommendation
A competitive sports anime about math competitions.
No anime, but there is a manga, "The Manga Guide to Calculus," written by a Japanese economist. There are other mangas about other topics as well.
Basophil: Welp my job here is done.
Cell: but you didnt do anything!?
Basophil: Didnt I? :)
Cell: :/
Basophil: :)
Basophil: (teleports away)
D-dante?
Is this a RWBY chibi reference?
I think he’s referencing the one Simpsons episode with leonard nimoy as a guest star.
Aw man, I remember watching this and thinking "I wish someone would explain everything that's going on here and what the cells are really doing." (Google seems to think that if you know a cell name you must be fluent in medical science.) Thanks for making it come true!
So tell me, doctor. Have you caught yourself saying/thinking "NANI?" to yourself when you're surprised yet?
Omae Wa Mou Weeaboo
I certainly do....
Anime fan here. I can proudly say no...
For me, it’s more along the lines of “Eeehhh!?”😱
I legit say that when I am shocked.
To be fair, I am Korean which is right next to Japan but you know what I mean...
Eosinophiles appear slightly orange-pink when you see them under the microscope 👍(pappenheim colouring)
I am a Medical Lab Technician and i love those litte details! :D
Is that part of how they get their name? Eos is the ancient Greek goddess/personification of the dawn, and the dawn is often pink and orange.
also, notice the shape of the Eosinophiles hat with the two furry sides compared to Dr.'s drawing of the cell :D
@@MrKlausbaudelaire true :D i missed that but their cores have this specific shape!
Miranda Bee Neutrophyl, baslophyl and eosinophyl got their names by dyes that they react to: neutral, base and acidic
... I love these little touches!
I have Idiopathic Urtucaria and my basophil level is over 4 times the normal (0.5% of TBC) level - I like to think my blood's full of cryptic ninjas who have no idea what they're doing.
TheMightyKawama
Sounds like a typical Rumiko Takahashi comedy. 😂
That's an amusing way to think about a disease. In my case, the T cells are going rampage and they have to be locked in a prison -.-
@@cactaceae378 No. There are many diseases out there, I don't have cancer. But I'm not getting into details.
@@cactaceae378 Sadly not an option, unless science finds a cure in the future ;) But I'm actually more optimistic considering how fast A.I. is improving. Or CRISPR, if you've heard of that. But I also have the usual autumn infection at the moment, so that should get better soon ;)
@@Lugmillord auto immune disease? Good luck bro.
"Obviously they put an ad break now"
*Dr. Hope puts ad break in the vid*
Oh you cheeky bastard XD
This was one of my favorite episodes. I'm not a big biology nerd, but the biggest "awwwww sheeet" moment was when the Anisakis showed up, and I realized that Eosinophil was carrying... a harpoon.
I never knew how bad-ass the inside of my body is!
Please take note: Eosinophil's hat is how her cell is constructed. Look at how Dr. Hope draws her cell, then look at the top of her hat!
Not just eosinophils, pretty much all the cells have hats refer back to their usual drawings! Just look at red blood cells and macrophages!
wow
I believe the reason why you are not super familiar with the bacterium in this episode might be because the Japanese people eat a lot of raw seafood and this type of seafood poisoning is much more common in Japan than elsewhere. Still, it's always interesting to see how culture and life style can effect which diseases are commonly observed in your community (I'm sure there are also lots of diseases commmon in Europe that Japanese doctors aren't familiar with as well).
I agree. Just like the Anasakis infection too
Im pretty sure a lot of coastal areas and/or people who specialize in food safety have heard of these bacterium and parasites.
6:20 Vibrio means that it has a shape like a comma, like the cholera bacteria (vibrio cholerae).
I love the fact that the Doctor learned something new from the anime. XD
Or more like a paisley. They always remind me of those patterns.
@@eldermillennial8330 Those are amoebas.
The only comment that nailed it... microbiology student here. I'm glad he got to read your comment!!!
To anyone who wants this series to continue you must stop article 13 it will ban any body to do stuff like this please don't let article 13 pass
yosapol pratyawiwathanadacha why will it stop you
@@IchigoMait Does that mean I can't use Shakespeare's books to kill spiders? Well fuck...
But what if no adds?
Aminulloh AS Doesn’t he have Patreon though
If I remember right, Article 13 only affects countries in the E.U. Just move to Murica, you’ll be fine.
if school was this interesting like this video, there would be Doctors everywhere :O
ikr! XD
ikr
If you have a good teacher it is. However, the medicsl field tends to be picky about whom to accept in. Plus, working with patients isn't for everyone (it sure ain't for me)
when an anime teaches to a doctor medical things
Continuing education is awesome
BaKa60 gaming wow
This was a fantastic analysis. I very much enjoy watching these, not just for reactions, but being able to learn from a charismatic doctor who is willing (and eager) to break things down into layman's terms. Thank you for doing these!
Culinary major here, and this poor guy probably ate MULTIPLE infected foods, since the vibrios are more associated with contaminated oysters, and anisakis simplex is mostly found in raw fish, at least according to my food safety notes.
Anyways, this is why we don't buy back-alley sushi. Because worms.
Brb lemme just- *(engulfs Asian market)*
When I was travelling in Japan, I tried out some conveyor belt sushi. And for the first time I got to try various raw fish aside from salmon and tuna.
At the same night, I could feel my stomach rumbling in discomfort. Not that painful to be alarmed, but, I'd imagine this very episode could be playing in my stomach.
Probably ate some cheap sushi at a sushi place. After all, show's made by Japanese, so they should have more experience with these types of things.
Well, in japaneese cuisnene your really likly to eat multiple seafoods in one dish.
@@mk_gamíng0609 Multiple seafoods, yes, but all infected (with different things)? That's certainly drawing the short straw.
16:41
Hope: And, boom. That's one dead parasite
Me: And judging by the eruption, one vomiting human
I really like his humbleness in his learning attitude towards something he doesn't know. I also admire that he says it portrays things in a "different way" when he sees that the pathogen eats up the WBC. He could've attacked the anime by saying "oh it's so wrong" but he did not. He has such a nice, respectful personality which we want in all doctors. Thank you for the great review!
Vibrio Enteritis is one of the common infections here to those that eat contaminated seafood (or at least around SEA where I live), so the name pops up pretty often when talking about food poisoning, especially among those that love to eat seafoods @@
In fact, in the Spanish subtitles they translate it as Vibrio parahaemolyticus, a gram-negative, mobile bacterium that does not have a capsule or spore, as well as tolerating common salt, which is why it develops in seawater and can grow at pH 9 in slightly basic media, which explains the infection caused after eating seafood :)
Thats why people who are against boiling seafood alive gets infected by vibrio bacteria more often compared to those who eats boiled seafood.
Jc Arroyo
I don’t see why you can’t put a knife through a lobster’s or crayfish’s head and then immediately throw it in the pot. I’ve never gotten sick.
Obviously the Japanese encounter this parasite more than anyone, since they eat more raw fish than anyone else.
@@cats140197 So here's the thing. I went and looked up that species of Vibrio and according to the site: www.health.state.mn.us/divs/idepc/diseases/vibrio/basics.html
and the subsequent image on Google: www.ehagroup.com/assets/img/site/pathogens/pathogen-vibrio-parahemolyitcus.jpg
It seems the images would add up that this person would in fact have this species of Vibrio bacteria, given the fact the miniature strands of Vibrio resemble the structure of the Google image. However, the site says you normally get that sort of infection from shellfish and oysters and is found in the US and Canada coast as well. Symptoms usually happen 24 hours after eating contaminated food.
Anisakisis on the other hand, or "Herring Worm Disease" can only occur if the host eats nematode egg infested raw fish or squid. www.cdc.gov/parasites/anisakiasis/faqs.html#what
Symptoms of course do include vomiting, abdominal pain, diarrhoea, etc, but what isn't said is that the nematodes not only burrow in the tissue, they tend to die when they reach the human body. If caught in the mouth or esophagus, the hoost can cough up the worms or pull it out of the mouth. If it's in the stomach, it's usually vomited up to expel the worm out. Remember when Eosinophil-san killed the nematode, and the stomach erupted as soon as it fell into the stomach acid? the body naturally induced vomiting to expel the foreign substance again.
So in this episode, not only do we know the host body ate either raw fish (sashimi) or raw squid, but it probably ate infected oysters or shellfish too. Probably went to a local sea-based restauraunt and the food quality was sub-par. We know that person won't make that mistake again for sure!
Don't worry Doctor, i get goosebumps too during the fighting scenes. This anime helps me to take better care of myself because all these cells are trying to keep me alive, the least i could do is make their job easier. I be like patting a random part of my body and say "Good job you guys" whenever i watched an episode xD
Me too! I actually looked up what vitamins my platelets needed cause I want them to be well fed.... 😳
In my case, my platelets are apparently trying to kill me, since I have Thrombophilia, but I still can relate myself to your new sense of self-care. I went to a Nutritionist soon after I watched the series, so I could help my good bois and gals inside me in good shape :)
lolol. You pat a random bodypart and say "Good job guys." Inside that bodypart: A mild earthquake shakes the city.
@@vikio452 ...................... good point.
Tbh tho. I take care of myself because I think of that romance of my cells I CANT HELP IT THEYRE GONNA DIE IN A SHORT AMOUNT OF TIME WHY WOULD I SHORTEN IT??
please redraw your family tree to a A3 paper.
since there will be many more cells coming.
There is a official cell family tree in the manga but it is not shown in the anime
Thank you for reacting this anime! I’m a japanese nursing student and I really love your reaction and classes😆
I can’t wait your next reaction! Thank you again!
BTW I’ve seen Anisakis in a raw oyster before...
"Obvoiusly they put an ad break now-"
**Ad plays**
Jay Katara haha I thought I was the only one who noticed that there’s literally an ad break right after he said that what a coincidence
Vibrio is a genus of "Gram-negative bacteria" that belongs to the order of Vibrionales, which is an order probably most well-known for causing Cholera.
I don't know if Cholera is a well-known illness in Europe, but here in the US it caused a scare a few years back, so that is why I used it as an example.
Stefan M. I’m not sure if cholera is still that much present but iirc there was outbreak of cholera in Europe before America was even discovered so Yeah we at least know it by name
Cholera is still used in languages like Polish and Ukrainian (both European) as a softer version of swear words. As a Ukrainian I can confirm.
27 dislikes from vibrio and its underlings
*its
They multiplied and it became 137
Heads up (NOT a spoiler), in later episodes, the subtitles say "antigen" and "heatstroke" in some areas. Just know that if in some of the areas where such terms are technically incorrect, it was the fault of the person in charge of the subtitles, the Japanese terms used are actually the correct ones. (informed by someone else who knows Japanese far more than I do)
pokeperson1000 you find that rather often when translations are involved.
@@toshiroyamada2443 Yeah, I know, but I just wanted to let him know. Didn't want him to think the show was being inaccurate.
I love, love, love the way you use your words to paint the picture of what goes on inside our bodies. For the majority of us, we will never see the inside of our body and yet we can through your words...great job! Love your channel!
Earlier this year I had to get my esophagus stretched. I’d been having trouble swallowing and had two serious choking incidents because of it.
The doctor took a biopsy during the procedure and when I woke up he told me I have “Eosinophilic Esophagitis”.
I think he was surprised at my response.
“Eosinophilic? As in Eosinophils? They’re immune cells right? So it’s some type of allergic reaction?”
I’m no med student....got that all from Cells at Work!
2:45 I love that you actually kind of lost your smile out of concern for Eosinophil getting knocked down.
A RUclips premier without a ton of dislikes? Man, your audience is far more patient and understanding than others out there
I have a feeling a lot of his audience is doctors....Because good doctors always have a lot of patients.
@@MikeWallibo Is that meant to be some sort of a pun
We're here for an education ☺️
Dammit I thought it was up already
same brother... same
or sister
Yeah me too! Clicked it so fast and got confused why it did not play
Stoopid RUclips.
Same. I kept tapping on the screen looking for the play arrow...
Just started watching cells at work because of your reaction videos. So my routine becomes watching the episode then going in here for the explanation so I can understand it clearer.
アニサキス（Anisakis）は、生の魚介類を寿司や刺身で食べる日本ではよく知られた要注意の寄生虫です。（感染すると凄く痛い！）
でも、ＵＫのDr.には馴染みがなかったようで、食文化の違いを感じられる楽しいお話でした。
Teacher: Are you alright? If you aren't feeling well go to the infirmary
Me: ugh, at this rate, the sea of hellfire will open the forbidden door!
Teacher: Nani!? *Proceed to give me a bag of plastic to throw up*
Yeah teacher knows exactly what it is XD
oppai japan
Your commentary is so wonderful. It's calming to hear, yet informative to where even someone like me, without any medical expertise can completely enjoy it. Thank you so much and I love this series of yours~
I am not a medical student, but I studied a lot of human biology, and I believe that the reason we didn't study some of these pathogens is because the Anime is directed to Japanese audience so it is logical that they explain to their children about the local diseases given that the Japanese diet is mostly seafood. Just another great perspective from the producers of this show
Its nort really the seafood itselfs it how they prepare it. The UK eats a a lot of fish but we tend too cook it, where as in japan its more common for it to be eaten raw and thats why we get diffrences in bacteria/viruses
Doctor Hope: “The medical term for being sick, we call Emesis”
Me: “...and that’s why things that induce vomiting are called Emetics.”
From what I've learned, the Anisakis is a genus of roundworm nematode.
From Japan
I enjoy watching your video.
I use too poor English to describe my enough Impression.
but it's very very very fun and cooooool!
I love your videos.
Good luck!
oppai
ゆずこしょう 私も日本人です！英語上手ですね！私もある程度は話せますが、やっぱり苦手です笑笑
@@BBQriblord から、どのは本当にいる
くそ。
他の日本語コメ欄含めて、随分となりふり構わない方が1名いらっしゃいますね。
覚えたての単語でたいそうにぎやかなご様子でいらっしゃいますところまことに恐縮でございますが、お隠れになれば大変幸甚に存じます^ ^
I noticed that cells at work focuses more on deseases and how they are defeated while Once upon a time... life focuses on the different organs ^^
Yes, you got that right!
Well Once upon a time... life tackles more topics such as organs than Cell at Work because obviously Cell At Work is focused around cells
Just wait for the slice of life spin off. Pun intended.
@@fennecCMD oh the spin off is nightmare
@@fennecCMD it is... a nightmare indeed
Waiting patiently for 11 hours. *Takes sip of tea*
Lol.
F for the dedication
1 hour left i think. how many sips of tea this far?
@@glattmasmas1485 Still 1 XD
@@glattmasmas1485
I damn well drank the whole pot. 🍵🍵🍵🍵🍵🍵🍵🍵🍵🍵🍵
“Obviously they put a ad brake now”
*AD POPS UP*
Your predictions throughout each episode are very, very accurate. They call you 'The Rogue Spoiler' in Japan.
For good reason, mostly hahaha
Vibrio is the genus to the species cholerae, which you can get through seafood.
Vibrio sp. are definitely not big enough to eat neutrophils by the way, but they do produce some nasty toxins.
@@Sebasstian86 Same genus, wrong species. Cholera is spread via the fecal oral route, not fish.
Cholera is not something you get every day unless your in a third world country or for early example lack of a sewage system in early centuries ago.
Basophils in general are not well understood. We know they're an immune cell, and that they participate in the immune reaction, but we're not entirely sure what they do, which is why the author made Basophil always speak in riddles and seem mysterious. Another neat easter egg in this episode is if you look at Eosinophil's hat, it looks just like the drawing of the Eosinophil because of the two-lobed nucleus. Same thing with Basophil, if you turn the drawing upside-down it looks like a mask, which fits even better with the mysterious vibe they were going for.
It's not just that Basophil speaks entirely in cryptic metaphor, it's also that so far only his fellow granulocytes like U-1146, Eosinophil, and Mast Cell have been able to vaguely understand the point he is making. Every other cell type in earshot of him has no idea what he's babbling about until a granulocyte translates him aloud.
The bacteria comes from contaminated seaFOOD, not seawater, and when 'it' eats our friendly white blood cell, it's because it's a "colony"! It absorbs him/surrounds him, I guess. I suspect we'll see him fight his way out later.
Edit: Yeah, he busted right out of there.
Love the show, keep up the good work!😊
Michael Berthelsen ooooo
Oh, thanks for the additional details. I was wondering why the White Blood cell got eaten. Now it makes sense.
Vikio If you look carefully, you can see LOTS of the tails of the individual bacteria sticking out from the big 'monster' that's actually the colony.
@@MichaelBerthelsen Ah, Yeah, at around 6:40 you see the "underlings". Then I took a good look at the "big guy" and now it's obvious that's just many of those individuals together. That's cool that the detail is there, but I'm surprised they didn't point it out in the show. They even made it so subtle that Dr. Hope didn't pick up on it. The percent of the audience who actually caught this reference seems too small.
MedTech/MLS student here and I swear to God this show has vastly improved my WBC counting times something about ascribing character traits to the cells helps me recognize them faster.
You seem to be having a lot of fun with this show doc! Can’t wait for you to see (and probably squee at) some of the less commonly known, more obscure stuff this show throws at its audience.
This is one of my favorite episodes of cells at work lol
Well, screw sleep for me. Time for Biology.
Yay, education
Haha, it ryhmed-
Yes
I've studied Vibrio as a veterinary student :D
Hello, I am just an innocent bystander
Hello i am just a non innocent bystander, **points whit a knife** the money or the life.
Please review episodes 6 and 7 togather. It's in my mind one of the best storys of this anime so far. It realy makes one think.
He will cover it.
And please, don't spoil things by saying it's episodes and it's content..!
now better?
@@LizardPendragon Yeap, better :) Thanks.
Because I haven't watched it myself. xD
@@michael22000 well the whole "twist" of the arc is bluntly advertised as log as you have some understanding of the workings of you body so I didn't thought this would qualify as a spoiler
That's just my opinion tho
By saying.
Can't wait you review the "topics" episode in episode 6 and 7.
Now I have a piece of information about episode 6 and 7, and I will be expecting it to happen.
Not that I can just erase what i saw tho.
But it's not really a problem for me, it's just kinda annoying that I just saw that while scrolling down the comments.
So i put down a comment. :)
But you already corrected it, so it doesn't matter anymore hehe.
I love how it shows that stomach acid can usually dissolve pathogens without the immune system having to get involved at all.
The acid is also important in protein and fat digestion, mostly breaking up and dissolving the big bits.
I love watching a well made anime with someone who is actually an expert in that field - it's such an enriching experience. Whether it's Haikyu with a volleyball player or Cells at Work with a doctor. Thank you so much for taking the time to share your knowledge with us all.
There is a series about a volleyball player watching haikyuu?
I live Japan (^ー^)
Sometimes we find Anisakis when we eat raw fish.
I think eosinophil hairstyle resembles actual cells.
(Google translation)
Electron oppai isnt the only japanese word in japanese language you know xD but i understand how you come up with that
ここにも日本人いたとは… 意外と探せばいるもんですねw
@@electron9259 are you just replying to every Japanese comment you see to be annoying or what? It's not funny.
@ゴミ はい
@@wireframehands133 いいえ。やめて
わたし？ not 私？
Look at her hat. Then look at your drawing of the actual Eosinophil.
I'm so impressed with the tools you used to explain the knowledge. Now I know the neutrophils are not big enough to fight with parasites (from your drawing) and how eosinophils fight and how basophils works (the cubes you use as chemical substances). Originally I think episode 4 anime is not as interesting as previous three episodes due to less information I can get from this chapter. Your video just compensate this and makes me like this episode more & more than before. Amazing!
I can’t tell you how much I loooove watching you analyze and go in depth about all the accurate information and well placed details. Just brilliant.
I'm currently a high school student and I've always admired people who can just talk about stuff on the top of their head. I wanted to be a doctor when I was younger but then found myself hating biology when I just entered high school, so now instead I'm focusing more on physics and chemistry. But for some reason I just find this series very entertaining to watch(although I have absolutely no idea what you are talking about when you explain stuff). I think it's just because that seeing a real doctor explaining stuff reminds me of what I thought doctors do when I was younger... Anyways please continue the series, I absolutely love it!
I love how nobody seems to know what basophil does.
If you noticed (which you didn't), the hat of the Eosinophil resembles the real life Eosinophil
Also the red blood cells' hat.
Talking to those who still say Red Blood Cell is a sickled red blood cell, which is wrong.
*EkoCakes*
Her cowlick is Sickle shaped at least.
@@Chemeleon15 again with that thing? How does that remind you of a sickle cell even if you (I assume) have seen many, *many* ahoges in anime/manga? How uneducated are you? Or just how new to anime/manga are you?
Geesh I'm salty. It's been months now and people still think she a sickled cell.
This is actually super interesting because Sushi isn't nearly as common in the West as it is in Japan, and since Sushi is more-or-less raw seafood it makes sense that they'd be more familiar with pathogens and parasites related to uncooked seafood while the same things are way more rare in other countries. So while Dr. Hope didn't know what it is, a Japanese doctor would probably be like "Yeah, I know this thing, it's this organism! I've heard of people getting that."
Always cool to see the effects of different cultures like this.
dracocrusher Anisakis and Vibrios are actually really present inside western seafood as well, but there is a huge difference when it comes to preparation. During import and fishing, the quick freezing of fish and seafood manage to make pathogens " fall asleep", so that they can be digested with no problems. Before preparing Sushi, restaurants must keep the food frozen for at least Two days!
In Japan, fish is bought the same morning at the market and there you have it, a bigger chance to get parasytes!
...Heh, sometimes fresh fish is far more dangerous, Who would have thought!
@@GTdba
Huhh, interesting
*the more you know!*
Lovely explanation and review once more, doctor-sensei. Medical student here, I really appreciate how you expound on an already wonderful show. Keep up your good work and also this service for the people not in the medical field. ❤
I feel kinda nauseous right now, watching this helps me cheer up knowing what my cells are doing.
はたらく細胞大好きなのでお医者さんに解説してもらえてとっても参考になりました！
これからも面白い回がまだまだ続くので楽しみです！
Hello! I am a fan of Japan. Your commentary is very easy to understand and it's fun so always looking forward to it! Good luck for your work
You're playing with my heart doc
I can’t stop watching these! I’m learning so much, even though I’m a designer and won’t really need this info 😂
While reading the blood smear the Eosinophil is color orange . 😍😍 One of my fav WBC.
i’m using wrights stain btw.
Eosinophil has pink clothing because eosinophils stain pink with eosin dye. FYI.
I'm wondering why she has pig tails?
Kawaii Universe because the shape of its nucleus look very much like a twin tails
Love this guy so much, what a wholesome video!
Thank you for this very interesting and entertaining series. Love the cute and easy to understand drawing.
The spring like bacteria at the start should be Helicobacter pylori. This bacteria looks like a spring and is able to attach to stomach. "Fun" fact it's the only bacteria known to directly cause stomach cancer.
The strange coton like bacteria is a "cousin" of the vibrio cholerae. Both can live in normal and salty (sea) water and give very aggresive diarrhea, especially if you are in vacation without boiling water.
I like the way the show treat the eosinophils and the basophils. The old way to identify them was to used red (eosin) and basic/blue (methylene blue) dyes, giving a red color to eosinophils and blue to basophils. Moreover they are very rare (
There is an individual chapter about Helicobacter pylori in the original manga, however it is not as same as this one. The Helicobacter pylori design in this series is much more bigger and scarier, and it can cause stomach cancer. Usually it keeps staying in the stomach because it can live with the gastric acid without getting destroyed
I also love how Eosinophil is pink and Basophil is greenish bluish here just like how it stains with H&E.
The black squiggles that you drew for the eosinophil cell look like Ms Eosinophil's pigtails :)
Another great episode! Interesting to note, when examining these cells under a microscope, eosinophils will uptake pink dye and the basophils will uptake blue dye - another interesting detail added to their designs (Eos' pink jumpsuit and Baso's blue headband)
And also if you noticed, Eosinophil has 2 connective nucleus, which is a reference for her hairstyle.
The pigtails.
Just a little info from a doctor working in Southeast Asia. Anisakis is actually a type of roundworm. I don't think I've ever seen a case of Anisakis penetrating the gastric lining. Could be a rare occurrence I'm not aware of, since these roundworms usually just produce mild symptoms, most often in Japan, where they consume raw fish. Anisakis infections are usually treated symptomatically, since humans are dead-end hosts to these particular parasites.
The checkered shirt is finally back again
I love cells at work, because as someone who has nothing to do with the medical community (yay film major), I'm also just fascinated with the human body and microbiology in general.
I absolutely love your reviews, because not only do I get to watch someone watch this show I love for the first time, I learn so much from it. It's so wonderful to learn from someone who loves what they do, and is falling in love with this show I adore. These videos are always a highlight to my day, thank you! I can't wait until the next one.
"I always get goose pimples"
You get w h a t
I prefer goose bumps omg
Love the videos though!! I loved this anime and having you review it and make comments to teach your viewers has helped me enjoy the show more. It's so cool having you explain something and then being able to connect it with something else I've noticed in the show. Keep up the great work!!