Real DOCTOR reacts to CELLS AT WORK! // Episode 5 // "Cedar Pollen Allergy"

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  • Опубликовано: 3 янв 2025
  • What happens when you have an allergy? We find out by watching Cells at Work (Hataraku Saibou) from a real doctor's perspective! I'll be breaking down what's on screen, reacting to the scenes and explaining a little more about the medicine and how the cells work.
    We learn about allergy, antigens, antibodies, mast cells and even steroid Terminators!
    As with all these reviews I skim over a lot of medical terms, please leave a comment if you want any clarifications!
    If you like this you can check out my look at the first episode here:
    • Real DOCTOR reacts to ...
    Or the second one here:
    • Real DOCTOR reacts to ...
    Or even the third one here:
    • Real DOCTOR reacts to ...
    Or even the fourth one here:
    • Real DOCTOR reacts to ...
    You can watch Cells at Work! here:
    crunchyroll.com...
    Be warned this video is again very medical / lots of talk about cell biology, so it's not just a straight up reaction, I try and bring something different to each video, so if you enjoyed this please check out my other reviews of Medical TV dramas; House MD, Scrubs, The Good Doctor, Grey’s Anatomy, The Resident and ER!
    Instagram: / drhopesicknotes
    Twitter: / drhopesicknotes
    FB: / drhopesicknotes
    Clips used under fair use (education and review):
    THANK YOU FOR NOT COPY STRIKING THIS VIDEO SO I CAN CONTINUE TO USE THESE GREAT SHOWS FOR EDUCATION AND REVIEW.
    ALL Cells At Work! Clips owned by Kodansha / Kodansha USA and distributor Sony Music Entertainment (Japan) Inc.
    Phagocytosis clip from Mr Riddz Science:
    • Phagocytosis Under the...
    Thank you to all the artists that make their music available for these videos:
    Song 'Escapists' by The AutoDisko
    Song 'First Day' by Huma-Huma
    Song ‘Finding Me’ by Eveningland
    #doctorreacts #doctorwatches #cellsatwork

Комментарии • 2,5 тыс.

  • @DrHopeSickNotes
    @DrHopeSickNotes  6 лет назад +3853

    I'm back! Been a busy few weeks for me, but so pleased to take another look at Cells at Work! Hope you enjoy... Anyone wondering about the hair curl I have throughout the video, it's a homage to Red Blood Cell and not a grooming malfunction :)

    • @jackbright2377
      @jackbright2377 6 лет назад +20

      Cool

    • @OutOfTheShadows1
      @OutOfTheShadows1 6 лет назад +157

      Dr Hope's Sick Notes Someday, you should watch Black Jack. its a 60s medical drama manga and anime by Osamu Tezuka, who's basically the father of that medium.

    • @grazelleavancena7804
      @grazelleavancena7804 6 лет назад +29

      My goodness, so happy to see this new reaction video of yours🤗. Been waiting for so long.

    • @Hanmacx
      @Hanmacx 6 лет назад +98

      Look at the Gun of B-Cell, it looks like the Protein

    • @ujwalamadishetty5571
      @ujwalamadishetty5571 6 лет назад +23

      First elon musk, a genius billionaire, and now an Doctor.... Soon... Anime shall conquer the hearts of all!!! 😂😂😂

  • @EclairPerversePastry
    @EclairPerversePastry 6 лет назад +4938

    "He's just a lost male sex cell in a protective layer trying to find a female flower to germinate." Aren't we all mate. Aren't we all.

    • @madpinoy5683
      @madpinoy5683 6 лет назад +589

      And just like the lot of us...looking in all the wrong places.

    • @kuromatsu1539
      @kuromatsu1539 6 лет назад +132

      @@madpinoy5683, EclairPerversePastry I don't know you or your stories. But for these comments alone, I Love both of you!

    • @hightiernub1313
      @hightiernub1313 6 лет назад +87

      Damn, that's deep.

    • @bahasapaaja8040
      @bahasapaaja8040 6 лет назад +24

      Please don't 😢

    • @Horizon_Flyer
      @Horizon_Flyer 6 лет назад +42

      I don't know why but this comment got me

  • @berkleypearl2363
    @berkleypearl2363 4 года назад +2434

    It’s nice to know that all of my allergies are caused by my body being just as much of a drama queen as I am

  • @Smokecall
    @Smokecall 6 лет назад +4567

    That moment when your doctor goes "Hold on, let me Wikipedia that"

    • @SlimTony
      @SlimTony 6 лет назад +442

      Cut us some slack, we can't know everything xD. Our brains are for thinking, not so much for remembering stuff anyways so don't get nervous when your doctor pulls out a spreadsheet or something similar (It is likely more accurate and up to date aswell).

    • @Smokecall
      @Smokecall 6 лет назад +128

      @@SlimTony the spreadsheet and other verified information is fine. When it's a publically modifiable resource it gets a little iffy.

    • @artificialintelligence8328
      @artificialintelligence8328 6 лет назад +187

      @@Smokecall
      Publicly modifiable, sure, but IBM researchers reported that "vandalism is usually repaired extremely quickly-so quickly that most users will never see its effects"

    • @Smokecall
      @Smokecall 6 лет назад +28

      @@valnimationid1371 that's completely fair

    • @lilotchie
      @lilotchie 6 лет назад +71

      yea now imagine your doctor tells you to hold on a moment he remembers there was an episode on that topic in an anime show you just need to quickly rewatch it to know how to deal with it xD I would probably burst out laughing my ass off dying happy xD
      sadly doctors in germany are generally old farts who would never agree to watch like cells at work unlike Dr.Hope does or they dont speak german very well...
      Would be awesome to be one of Dr. Hopes patients, probably

  • @painnful
    @painnful 5 лет назад +2952

    Mom: anime isnt educational
    Red Blood Cell: hold my oxygen

  • @NikkiTheViolist
    @NikkiTheViolist 5 лет назад +1321

    "This wouldn't really happen in real life"
    What, do you mean I don't have little red-wearing anime girls running around my blood delivering boxes and all-white guys with knives hunting rogue bacteria?

    • @KaiNoisseggra
      @KaiNoisseggra 4 года назад +7

      Lloooollllllll XXDDDD

    • @liltone9614
      @liltone9614 4 года назад +54

      This happens in my body all the time

    • @Bluemilk92
      @Bluemilk92 4 года назад +44

      I believe, Socrates theorized you can't _know_ anything. So I would say it is rather unlikely, *but*
      Well... Let us just say, fingers crossed, eh?

    • @danielpan6909
      @danielpan6909 4 года назад +9

      no but in fact what we have is even more sophisticated, delicate and badass

    • @SwordTune
      @SwordTune 4 года назад +7

      If not... Then what is the point of living?

  • @ArtFreak17
    @ArtFreak17 6 лет назад +4277

    I cackled at how you delivered, "Awww... the poor pollen! He's very harmless, he's just a lost male sex cell in a protective layer, trying to find a female flower to germinate. But, he's just looking in all the wrong places!"
    (I'm really enjoying this series from you!)

    • @plant5875
      @plant5875 6 лет назад +5

      S. Holloway hmm

    • @rotwilk1
      @rotwilk1 6 лет назад +296

      Better love story then twilight.

    • @LinkeLars420
      @LinkeLars420 6 лет назад +18

      So humble~

    • @cubeofmeat4982
      @cubeofmeat4982 6 лет назад +37

      Better love story than Boku no Pico

    • @SakuraAvalon
      @SakuraAvalon 6 лет назад +16

      Spirit Resonance That was a love story?

  • @marinapadilla3307
    @marinapadilla3307 6 лет назад +1305

    "Every story benefits from a terminator with a mini-gun", so true.

    • @demonminer8093
      @demonminer8093 5 лет назад +13

      @Samuel A. Lim Are you certain that the story suffers with the addition of a mech with a minigun? i think it would be bloody awesome if Harry Potter was an anndroid created to hunt voldemort down. but whatever, i guess...

    • @SpookySquid14
      @SpookySquid14 5 лет назад +12

      Demonminer sleeping beauty doesn’t eat an apple she gets shot by the terminator endoskeleton

    • @Lemonsrt
      @Lemonsrt 5 лет назад +6

      Sam Lim red riding hood would be so much better with a massive gun

    • @andrewlance3898
      @andrewlance3898 5 лет назад +6

      Un Limon **coughRWBYcough**

  • @bryntendo
    @bryntendo 6 лет назад +1420

    I would've loved to see the cedar pollen just wandering around the place looking confused, like a big dumb marshmallow who was just blown in out of nowhere, while the immune system went absolutely nuts around it, attacking it in a panic, damaging the body in it's attempt to keep it safe

    • @Nobythulhu
      @Nobythulhu 6 лет назад +50

      Bryn Jackson
      Oh, that would have been so good!

    • @soulfox32
      @soulfox32 6 лет назад +219

      That's kinda what happened here, since they aren't even attacking but just looking around

    • @yeowo
      @yeowo 6 лет назад +259

      Pollen: “Ccceeeeddaaarrr????”
      Everyone else: “aaaAAAAAAAHHHHHHHHHHHHHHHHH”

    • @chadmulyadi5025
      @chadmulyadi5025 4 года назад +35

      POOR POLLEN THEY'RE SO CUTE :"

    • @Dreq458
      @Dreq458 4 года назад +6

      @@chadmulyadi5025 well as cute as sperm can be, I suppose

  • @Defty-picklez
    @Defty-picklez 5 лет назад +1464

    the memory cell has PTSD

    • @hopesy12u4
      @hopesy12u4 5 лет назад +57

      DONT NOBODY TOUCH THE LIKE BUTTON

    • @saimahramen
      @saimahramen 5 лет назад +29

      @@hopesy12u4 ... I just did.

    • @River_Katerina
      @River_Katerina 4 года назад +11

      Uh
      Uh
      I
      I don't know how to respond to that

    • @AuroraLalune
      @AuroraLalune 4 года назад +4

      No. Please don't do that.

    • @purinharumaki3191
      @purinharumaki3191 4 года назад +3

      Too bad I already did it.

  • @Sea_Maranatha_
    @Sea_Maranatha_ 6 лет назад +1063

    "The tea getting spilled- that's a very English problem we can relate to that" 😂😂😂 I love your reactions/commentaries
    Not only educational but also funny haha

    • @Pikyoh
      @Pikyoh 4 года назад +4

      Ha- *starts choking*

  • @DerklyLiu
    @DerklyLiu 6 лет назад +1773

    I actually moved to Japan a little over a year ago and the typical medications people use can be a bit different from the western world.
    In terms of pollen allergies, people don't typically take antihistamines, and instead wear surgical masks to limit the amount of antigens entering their bodies. People where I live only typically take medicine when the symptoms are especially bad, and rather than histamines it would be steroids. This might help explain why the show went the steroid route rather than the antihistamine route for the episode.

    • @chunt5584
      @chunt5584 6 лет назад +227

      On that note, an old surgeon in my med school who traveled the world also noted that different population in the world has vastly different sensitivity and reaction to anesthetic agents. Interesting stuff.

    • @6666Imperator
      @6666Imperator 5 лет назад +176

      I mean its a japanese anime so it makes sense that they orientate on more common things there (like with the sea water/food stuff in the last episode in combination with raw fish)

    • @Mernom
      @Mernom 5 лет назад +40

      @@chunt5584 That makes sense - Isolated populations (even if not nearly as much as they used to be) tend to share similiar traits, including suseptability to certain sicknesses. And since Alergies are usually not leathal, they're not stopping the person from passing it on.

    • @b.collins2656
      @b.collins2656 5 лет назад +106

      it also explains why the plant pollen is from cedar trees and not, like, ragweed or grasses, which is what's common in america. i was also really surprised about how cells at work chose to use steroids, because americans tend to see steroids as a big boy drug that's really only used when otc options don't work

    • @AMoniqueOcampo
      @AMoniqueOcampo 5 лет назад +12

      Well that explains a lot. I was seriously nitpicky about the whole steroid thing.

  • @wessltov
    @wessltov 6 лет назад +781

    Terminator-steroid doesn't care who's fault it is. Terminator-steroid just wants the body to just chill out for a while

    • @TriaMaxwell
      @TriaMaxwell 6 лет назад +78

      So.... Terminator-steroid is a mom?

    • @wessltov
      @wessltov 6 лет назад +79

      @@TriaMaxwell I mean, if your B-cell son and Mast-cell daughter were destroying the house fighting, wouldn't you just ground them both?

    • @TriaMaxwell
      @TriaMaxwell 6 лет назад +19

      @@wessltov Hey, B cell started the fire, Mast cell just tried to put it out

    • @RoyalKnightVIII
      @RoyalKnightVIII 6 лет назад +8

      If this is ever dubbed they need an Ahnold soundalike for the steroid Terminator

    • @-nathun8507
      @-nathun8507 6 лет назад +6

      Tria Maxwell
      we didn’t start the fire
      It was always burning science the worlds been turning

  • @scolipede491
    @scolipede491 6 лет назад +2927

    Well you realize you have to show us your cat now, right?

    • @sheepfish6263
      @sheepfish6263 6 лет назад +220

      Duh! Basic internet laws and all!

    • @DrHopeSickNotes
      @DrHopeSickNotes  6 лет назад +467

      Here she is:
      instagram.com/p/Bq1uwGsBz1Z/

    • @sawa139
      @sawa139 6 лет назад +157

      Floof

    • @chriscrow4710
      @chriscrow4710 6 лет назад +116

      @@DrHopeSickNotes so fluffy like my pillow

    • @Ikajo
      @Ikajo 6 лет назад +9

      @@DrHopeSickNotes I also have a black and white cat, although he is male and indoor only.

  • @user-be3vz3mc4u
    @user-be3vz3mc4u 5 лет назад +426

    In Japan, after the war, we actively planted trees to meet the increasing demand for timber, but we still have many left over because we chose cedar trees that grew fast at the time. There are still many people with hay fever. In Japan, 1 in 3 people suffer from cedar pollen. I am also troubled by pollen other than cedar trees. I'm sorry if my English didn't' make sense.

    • @teodorodensing351
      @teodorodensing351 5 лет назад +41

      Hey, your english is good! Omedetou!

    • @SpitfiretheCat16
      @SpitfiretheCat16 4 года назад +24

      Literally the only error you currently have is an erroneous apostrophe; you've got a level of English comprehension that I would associate with those that use their second language as a major component of their job. That's fluency nearly on par with native speakers, and the only reason I say "nearly" is because the structure is a bit strange- certainly nothing that could be considered incorrect, just not perfectly natural. You're doing a fantastic job and you'll only continue to get better, but I consider this mastery already.

    • @nikagoesoffline5675
      @nikagoesoffline5675 4 года назад +10

      Its ok :3 as my mother says, as long as people understand you who cares about grammar.

    • @miz778
      @miz778 3 года назад +10

      Thank you for your feedback regarding the cedar pollen! Not only do I learn science here, I also learn a little bit about Japan

    • @immortalsun
      @immortalsun 2 года назад +5

      Your English is great

  • @戸沢白雲齋
    @戸沢白雲齋 6 лет назад +794

    The voice actor of Cedar pollen is Tessho Genda.
    He also plays Arnold Schwarzenegger of Japanese version.
    And Optimus Prime

    • @SpookySquid14
      @SpookySquid14 5 лет назад +53

      Now I want to see the scenes with the pollen allergy but with Optimus voice clips

    • @farzanafizul6215
      @farzanafizul6215 4 года назад +38

      Cedar Pollen: "I'll be back!"

  • @ちくわたらこ
    @ちくわたらこ 6 лет назад +1319

    I'm japanese high school student. Thanks to this video, I can understand about working cells. I'm sorry about my bad English but I wanted to tell you Thanks.

    • @NaBa.O3O
      @NaBa.O3O 6 лет назад +156

      Your english was pretty good here, don't worry.

    • @lizadonrex
      @lizadonrex 6 лет назад +64

      Not bad English! Do you know the Japanese already make Japanese subtitle on this reaction video?

    • @iamgeegee1258
      @iamgeegee1258 6 лет назад +19

      You are good, keep it up

    • @ちくわたらこ
      @ちくわたらこ 6 лет назад +57

      Thanks!
      Yes! I saw translated video at first.

    • @momochi5230
      @momochi5230 6 лет назад +14

      Your english is fine

  • @brycevo
    @brycevo 6 лет назад +2035

    I'm glad this Series is back. I really like your feedback and take on this show!

    • @mfs4708
      @mfs4708 6 лет назад +15

      So am I. Support this series!

    • @Snorlax9
      @Snorlax9 6 лет назад +7

      We all do

    • @brycevo
      @brycevo 6 лет назад +1

      Thank you for the ♥️, Doc

    • @tpmiranda
      @tpmiranda 6 лет назад +3

      Hope it ends before Article 13. Otherwise, these series will never end... :(

    • @plant5875
      @plant5875 6 лет назад +1

      sameee

  • @MonsterMoloch
    @MonsterMoloch 6 лет назад +526

    "Every story benefits from a terminator with a minigun" XD

  • @IrvinCascade
    @IrvinCascade 6 лет назад +392

    As a scientist, myself, I absolutely loved the series and their take on the intra/intercellular communications and how everything worked out, finally even bringing up phagocytosis, showing the ridiculous overreaction, showing how useless eosinophylls would be toward bacterium, while being a powerhouse against parasites, and the adorable platelets... And Dr. Hope's take on this all did excellent in breaking down the highly complex situations and comparisons and simplifying it, further-explaining what the show only touches on in a more technical sense.
    It's actually pretty funny; because, I'm literally going through a good number of these situations (Outside, of course, of the parasite and the food poisoning). It's nice to see how the anime heroes in my body are combating the illness and allergic reactions I'm currently facing, as well as how the steroid I just had to take unleashed a damn robot to wreck the membranes of my body's cells.

  • @0AngelOnTheDanceFloor0
    @0AngelOnTheDanceFloor0 6 лет назад +533

    ''He's very harmless, he's just a lost male sex cell in a protective layer, trying to find a female flower to germinate. But, he's just looking in all the wrong places'' Me if I was a male

    • @coco-ro9pb
      @coco-ro9pb 6 лет назад +17

      Satan is female confirmed

    • @0AngelOnTheDanceFloor0
      @0AngelOnTheDanceFloor0 6 лет назад +26

      And they thought god was a woman

    • @wessltov
      @wessltov 5 лет назад +6

      @@0AngelOnTheDanceFloor0 Anime seems to think so

    • @HeIsAnAli
      @HeIsAnAli 5 лет назад +1

      @@0AngelOnTheDanceFloor0 I understand that reference!

    • @sarahackroyd2150
      @sarahackroyd2150 4 года назад +6

      the way you phrased that implies that you are not a male, but that you ARE a cedar pollen.

  • @chrisroserva
    @chrisroserva 6 лет назад +546

    I'm a non-native English speaker and not even a medical student, yet I enjoy your reaction to cells at work all the same, fun and educational. Great job!

  • @moonlightray8493
    @moonlightray8493 6 лет назад +728

    The design of those cedar pollen molecules are actually pretty cute, tbh...

    • @sarang-archer
      @sarang-archer 6 лет назад +65

      right??? I've wanted a plushie of them ever since I saw them in the manga for the first time

    • @wildsharday9652
      @wildsharday9652 6 лет назад +11

      They remain me of them candy thing called Peeper if am sleeping them right.

    • @dandanthedandan7558
      @dandanthedandan7558 6 лет назад +20

      Pray and hope someone makes a merch of cedar pollens

    • @OverseerMoti
      @OverseerMoti 6 лет назад +30

      A cedar pollen plushie with actual cedar pollen inside...

    • @dandanthedandan7558
      @dandanthedandan7558 6 лет назад +27

      @@OverseerMoti are you trying to cause B Cell and Mast Cell to argue?

  • @kelpzie
    @kelpzie 6 лет назад +542

    your cats little pawprints on the bacteria drawing was absolutely crucial to my enjoyment of this video

    • @CryingZombie666
      @CryingZombie666 6 лет назад +37

      That's how you kill a bacterium. By letting your cat boop on it.

    • @s70driver2005
      @s70driver2005 6 лет назад +2

      Totes man crush when he said he had a cat!!

  • @ThreadBomb
    @ThreadBomb 6 лет назад +382

    I loved Ed talking about the different reactions to medical emergencies!
    JUNIOR: The patient is vomiting blood!
    SENIOR: Not good.
    JUNIOR: The abdomen has opened and I can see the bowels!!
    SENIOR: I see. Anything else?
    JUNIOR: The patient is on fire!!!
    SENIOR: Hmm. I might be able to get a paper out of this....

  • @kinuly1174
    @kinuly1174 6 лет назад +487

    ste 'roid'
    roid->robot
    crazy machine gun which kills everything.
    Nice play on words :)

    • @lpfan4491
      @lpfan4491 5 лет назад +9

      a roid being on roidrage = cool

    • @azuxiv
      @azuxiv 4 года назад +12

      ain't japanese anime if there's no wordplay! XD

    • @早川眠人
      @早川眠人 3 года назад

      It's a nice point of view.

  • @Lengzxc
    @Lengzxc 6 лет назад +522

    "Just wear sunglasses, they make you look cool" 🕶

    • @dracocrusher
      @dracocrusher 6 лет назад +23

      "If I look cool I can avoid my blood being shot at by the Terminator."
      "Oh...... Okay then...."

    • @ShinThedreamer
      @ShinThedreamer 6 лет назад +18

      Medical and fashion channel at the same time

  • @jaredavnet6663
    @jaredavnet6663 6 лет назад +727

    Do you think they made the medicine a robot because it's a chemical rather then a living cell?

    • @vanilla_milkshake
      @vanilla_milkshake 6 лет назад +199

      I thought the same thing! It's an artificial machine made to mimic a living cell: a robot!

    • @MajorMalfunction
      @MajorMalfunction 6 лет назад +78

      Aye. An artificial synthetic chemical, which is kinda indiscriminate overkill. It doesn't really have a specific target.

    • @mechasatsu6214
      @mechasatsu6214 6 лет назад +159

      Also a nice wordplay. Since the medicine taken is SteROID. Like an Android.

    • @dplocksmith91
      @dplocksmith91 6 лет назад +38

      I always thought of viruses as sort of organic robots. Unliving, though they are made of some of the same substances as living beings.

    • @Bananaguy7
      @Bananaguy7 6 лет назад +32

      dplocksmith91 that’s why the viruses are depicted as zombies. They are organic, but not living

  • @tuesday1672
    @tuesday1672 5 лет назад +208

    Me: mom I don’t want to be a doctor
    Also me: *watches a doctor watching a medical anime*

  • @Horizon_Flyer
    @Horizon_Flyer 6 лет назад +97

    This helped me realize that when my allergies act up that it's just my body over reacting to dust and pollen.

  • @zjzr08
    @zjzr08 6 лет назад +204

    A slight character detail he didn't show, is that WBC was actually sad about killing the cedar pollen, but needing it to be dispatched hence why he paid respects to it when it died, which will be an character trait for an important episode later on.

  • @thehumus8688
    @thehumus8688 6 лет назад +547

    The machine gun / gatling gun might reffer to suppression of Imune system by steroid
    In military automatic weapon commonly used to deliver supresing fire to pin down enemy

    • @DrHopeSickNotes
      @DrHopeSickNotes  6 лет назад +87

      Like this!

    • @babull4751
      @babull4751 6 лет назад +5

      @@DrHopeSickNotes The T Cell brigade we see actually have a memory cell, he has a filder with hearts on it. You can see him in the T Cell explanation in the influenza episode. Im pretty sure that he is in that freeze fame, I know for sure that he is in that episode.

  • @CaptainMarvel4Ever
    @CaptainMarvel4Ever 6 лет назад +327

    This is so much better than other non-content based reaction videos. Love the way you stop things and then use visual effects and analogies to make the learning fun. Very professional and inviting.
    Also, kind of apropriate the cat muked up your cell a bit since cats can carry a lot of pollen in their fur and often cause allergies themselves.

  • @omnitricks29
    @omnitricks29 6 лет назад +278

    Interviewer: This job requires you to have a PhD in Human Microbiology.
    Me: Not to worry. I've watched all episodes of Cells at Work.
    Interviewer: OH S**T YOU HIRED!!!

  • @kaseiryu
    @kaseiryu 6 лет назад +23

    I really like that the steroid didn't actually kill the cells, but it scared the heck out of the mast cell and B-lymphocyte which suppressed their activity. The level of detail this show works on sometimes feels like Easter eggs. Your input is a fantastic addition to this really fun bit of education (supplement?). I've suggested this show and your reaction series to my microbiology professor for his intro to microbio course.

  • @lavaforevah
    @lavaforevah 6 лет назад +344

    But srsly this dood really does magic with this :o
    Like,he makes 2 of my fav things into one
    ANIME AND SCIENCE!
    Cheers for this guy! :D

  • @mechadense
    @mechadense 6 лет назад +398

    Now I'm sure of it. "Cells at Work" is a misnomer. This show should have been called "Cells at War".

    • @Fenris30
      @Fenris30 6 лет назад +61

      That Cells at Work Black.

    • @blubyrd518
      @blubyrd518 6 лет назад +4

      oh nuu theres a hemmoraghic shock at episode 12 (sorry if i spelled anything wrong)

    • @idjthesmart1363
      @idjthesmart1363 6 лет назад +34

      When war occurs everyday it just becomes another task of work

    • @Soken50
      @Soken50 6 лет назад +31

      when it comes to the immune system it really is a professionnal army, so they are "just doing their job" like any day.

    • @horacehorace6793
      @horacehorace6793 5 лет назад +9

      @@joshgellis9463 wait wat

  • @jaspersiron1041
    @jaspersiron1041 6 лет назад +431

    The B Cell’s gun is Y shaped. Very nice illustration

    • @hanablake9927
      @hanablake9927 6 лет назад +32

      Jasper Siron When he showed the real form of B Cell i thought the same!
      This anime is so creative 💜

    • @melaniemarfiga9489
      @melaniemarfiga9489 6 лет назад +11

      Once again another thing i missed from this show! I've always wondered why B cell's gun is the way it is... I should've known! XD awesome job by the creators of the show

    • @izzy_theog9658
      @izzy_theog9658 6 лет назад +4

      The "Y" shaped gun is B Cell's Antibody Gun that releases IgE

    • @Mononclus
      @Mononclus 6 лет назад +1

      Antibodies be like the Fan o War
      Thats how i remember :P
      Also, Ive studied a bit of immunology decided to take a look. Although it seems correct on most scales, its anime, so you have the casual exageration and cringe
      IgE is the bane of my existence

    • @Syntania
      @Syntania 6 лет назад

      @@izzy_theog9658 In this case (allergies) it is IgE. There isn't an "IgN".

  • @dreajp
    @dreajp 5 лет назад +52

    I'm sorry. I just lost my shit when he was like "I'll find once I EAT IT!" 😆😆😆😂😂😂

  • @thxtmerrywxnderer9085
    @thxtmerrywxnderer9085 5 лет назад +58

    Bursa of Fabricius is involved in B cell development in birds!
    Even as a vet student, I loved the show and I thoroughly enjoy your explanations throughout the video. Looking forward to your future videos!

  • @davidguthary8147
    @davidguthary8147 6 лет назад +183

    Just a little side note: the Memory Cell in this episode isn't a T Cell. He's a Memory B Cell. In the show, he's shown running a library filled with information about previous infections, which B Cell uses to make his antibodies.

    • @DrHopeSickNotes
      @DrHopeSickNotes  6 лет назад +59

      David Guthary awww my mistake. Thanks for clarification

    • @Lexiand
      @Lexiand 6 лет назад +17

      Dr Hope's Sick Notes yup. You probably thinking that certain military guy with a pink notebook. 😁

    • @TriaMaxwell
      @TriaMaxwell 6 лет назад

      @@Lexiand Dendrite?

    • @Winu-bignsmall
      @Winu-bignsmall 6 лет назад +9

      Tria Maxwell no there IS a memory T Cell appearing in the Influenza episode. He does look like the black uniform-ed military guys (like the Killer T cells does) but his hat says “MEMORY” (not the usual “KILLER”) and he brought a pink heart patterned notebook.

    • @TriaMaxwell
      @TriaMaxwell 6 лет назад

      @@Winu-bignsmall Sorry. 3:35 AM here. Thanks for the correction. So do you go dawwwww when you see platelets?

  • @brigidtheirish
    @brigidtheirish 6 лет назад +39

    The way I see all the destruction and mayhem seemingly being caused by the pollen is how the cells perceive the 'invasion.' In that one scene you showed, it seemed like the panicking cells knocked into the pollen, *pushing* it into the building. So it was still the cells over-reacting that caused the damage and misapplying blame.

  • @kirztiejoseph6624
    @kirztiejoseph6624 6 лет назад +554

    I cannot believe how fast I clicked on this video when it popped up ☺️☺️👍🏾

    • @subcon888
      @subcon888 6 лет назад

      same

    • @baltakatei
      @baltakatei 6 лет назад +1

      I can say these videos are for learning and not just an excuse to watch cute animated girls.

    • @stephaniest.5336
      @stephaniest.5336 6 лет назад

      Likewise

  • @robinnohood5557
    @robinnohood5557 6 лет назад +403

    My teacher asked me why is my Biology so good
    I answered:"ANIME"

  • @YokoshimaSTAR
    @YokoshimaSTAR 6 лет назад +66

    *At Doctors meeting:*
    Doctor: Why're you late?
    Doctor: I was watching anime.

  • @Geolaminar
    @Geolaminar 6 лет назад +319

    "Tea being spilled, that's a very English problem, I can relate to that."
    As a American, and a citizen of Boston, Massachusetts....
    [[[[[[[[[[[PATRIOTIC FREEDOM INTENSIFIES]]]]]]]]]]

    • @King0fYou115
      @King0fYou115 6 лет назад +4

      Tristan Ritland xD

    • @FFKonoko
      @FFKonoko 6 лет назад +8

      Don't worry, you're very free from good tea. *sips*

    • @IMVADER2
      @IMVADER2 6 лет назад +16

      @@FFKonoko Don't worry, our $1, tax-free arizona tea cans are tripled in price in the UK
      **chugs**

    • @MikeRees
      @MikeRees 6 лет назад +10

      Even if it were a third of the price it probably wouldn't sell. We chose India over the US to keep for a reason

    • @dashiellgillingham4579
      @dashiellgillingham4579 6 лет назад +9

      *is drinking chi tea out of an eagle mug at this exact second.*

  • @MemesToa
    @MemesToa 6 лет назад +137

    I never knew how much I needed to see a Steroid Terminator until this day

  • @Krystianosik
    @Krystianosik 6 лет назад +115

    -What's your name?
    -Doctor.
    -Doctor who?
    -Doctor Hope.

    • @lordofrims
      @lordofrims 6 лет назад +7

      Doctor? Who's a Doctor? (DW - S1E1 1963 - An Unearthly Child)

    • @rejisuke9999
      @rejisuke9999 6 лет назад +2

      Oh you're using your make-up name.

  • @arrowherbert3478
    @arrowherbert3478 5 лет назад +52

    The Memory cell shown here is actually a Memory B cell, it's more explicit in the manga, showing how they share an office space and work on problems together. A memory T cell shows up later on when the main Killer T cell becomes one.
    PS
    I love how you stop to visually explain the real science behind what is happening in the show!

    • @FenrirAldebrand
      @FenrirAldebrand 3 месяца назад

      Yes! And just like the hilarity of the red blood cell that's always lost, we have a memory B cell who struggles to remember 😂.

  • @GearShotgun
    @GearShotgun 4 года назад +12

    The fact that a doctor calls this good prep for med school is amazing

  • @conormurphy4328
    @conormurphy4328 6 лет назад +734

    6:33 what.. what are you talking about? Is this not what’s really happening in my body?

    • @barbaraprice5389
      @barbaraprice5389 6 лет назад +44

      They are literally snot rockets

    • @ferociousmaliciousghost
      @ferociousmaliciousghost 6 лет назад +47

      @Gilbert Ber2 Careful on what you say there. The FBI might bust your door.

    • @crulius.pontanian
      @crulius.pontanian 6 лет назад +17

      @Noblesse Obligee um that platelet is likely only a few days old, so yea it is definitely underage (they only live 8-9 days).

    • @LassieRF
      @LassieRF 6 лет назад +21

      @@crulius.pontanian no bro. you're forgetting to scale their age maturity according to their max life expectancy. young adults sounds about right

    • @VashdaCrash
      @VashdaCrash 6 лет назад +7

      @Noblesse Obligee I think you just described the premise for some doujinshi that may be already released in some corner of the last comiket. LOL

  • @MrFForger
    @MrFForger 6 лет назад +69

    "Every story benefits from having a Terminator with a mini-gun."
    Words to write by.

  • @nicolasng3614
    @nicolasng3614 6 лет назад +889

    Can't wait until you get to the Cancer episode, it's an emotional one.

    • @richie6497
      @richie6497 6 лет назад +14

      Hint hint*

    • @nicolasng3614
      @nicolasng3614 6 лет назад +89

      Richie 64 more like *Spoiler Spoilers

    • @fluffyphoenix8082
      @fluffyphoenix8082 6 лет назад +96

      Cancer might be my favorite character in the whole show/manga, besides our main white blood cell himself. ...Which sounds really weird out of context lol

    • @rheajean0711
      @rheajean0711 6 лет назад

      True 😭

    • @kuragari9846
      @kuragari9846 6 лет назад +3

      kaneki ken :(, he didn't want to become a ghoul, just like cancer sama

  • @hellengonzalez3005
    @hellengonzalez3005 6 лет назад +56

    Look at the way that you designed the antigens. It has the same design as the gun that the B cell has. 😂

  • @hyakkaryoran175
    @hyakkaryoran175 6 лет назад +41

    Really enjoying your review on the series! A nice refresher for immunology - this coming from a biomed student :)

  • @pickaweedia
    @pickaweedia 6 лет назад +109

    And the ad on the video: Mucinex. Perfect.
    Yet another really enjoyable video; thanks Dr. Hope!

  • @Thunder_Herrscher
    @Thunder_Herrscher 6 лет назад +111

    Oh my god I love your reacts. I swear you make watching this show better and better. I'm glad to be learning from you. THANKS!

  • @ybrikman
    @ybrikman 6 лет назад +114

    As an Engineering student, this is so awesome

    • @adibbazli
      @adibbazli 6 лет назад +6

      Kirby Salonga Try to create Steroid Robot! XD

    • @lil_jong-un6668
      @lil_jong-un6668 6 лет назад +3

      One doesn't need to be an engineering student to be amazed by this.

  • @oliverkirkland420
    @oliverkirkland420 6 лет назад +194

    "prevention is better than-" *ad plays*
    soooo get adblocker basically?

  • @abbyhae
    @abbyhae 4 года назад +15

    I find it more enjoyable to watch doctors reacting to Cells at work rather than just me watching the anime and then having to google from time to time 😅😅😅

  • @zjzr08
    @zjzr08 6 лет назад +122

    A wild Cells at Work! review appeared! 😮 I actually wondered what happened, not seeing ANY Sicknotes video for the past 3 weeks. Last time I saw something Cells at Work! related was in an Instagram snippet in the 86th Floor Cosplay where a certain doctor is wearing a cartoonish cosplay of a bacteria. 😂 Nice to see you still continuing the series...#6 is an episode with chock full of information to discuss too.
    P.S. Cells at Work! will air a winter special around December 26 and I think it may be aired on Crunchyroll, so if you can make a review close to that time, it would be great, seeing it would just be fresh.

  • @SeraphinaAizen1
    @SeraphinaAizen1 6 лет назад +93

    I'm really enjoying this ongoing reaction series. Definitely keep it up. "Steroid Terminator" may be my new favorite phrase.
    Side-note: The "Helper T Commander" cell is unexpectedly attractive.

    • @mishellemacias
      @mishellemacias 6 лет назад +2

      in later episodes you'll watch more about him and his story

    • @Sea_Maranatha_
      @Sea_Maranatha_ 6 лет назад +8

      ... He is... So is the White cell....
      We have reached a point in humanity where we find body cells attractive (I know they're kind of represented like people but still), I-

    • @someoneawesome8717
      @someoneawesome8717 6 лет назад +1

      @@SeraphinaAizen1 NK Cell if gorgeous

    • @ls200076
      @ls200076 6 лет назад

      @@SeraphinaAizen1 Just do it!
      Feel the warmth and shield that he provides for you.

    • @owltoe0164
      @owltoe0164 6 лет назад

      Mama macrophage is goat

  • @MrKlausbaudelaire
    @MrKlausbaudelaire 6 лет назад +112

    never clicked a video so dam fast, I might have caused some of my red blood cells on my index finger to wonder what the hell was the "earthquake" about.

    • @TriaMaxwell
      @TriaMaxwell 6 лет назад

      As long as you didn't get an "abrasion" from that stray piece of paper while you did it.

  • @cybershadow4112
    @cybershadow4112 6 лет назад +52

    I'm so sad, he switched his electric guitar for an acoustic. I was so used to the electric guitar.

  • @Deedo_67
    @Deedo_67 4 года назад +16

    “He’s just a lost male sex cell in a protective layer trying to find a female flower to germinate.”
    That’s deep

  • @zhchee7734
    @zhchee7734 6 лет назад +51

    I find it a nice little detail that the gun the B Cell is holding is the same shape as an antibody (a Y shape). Neato!

  • @onniekunnu2940
    @onniekunnu2940 6 лет назад +49

    20 minute vid?! What a special day for me.

  • @jakobsletten624
    @jakobsletten624 6 лет назад +22

    his voice is so friendly and sincere

  • @hsping9386
    @hsping9386 6 лет назад +117

    7:47 cat owners can relate

    • @NetherStray
      @NetherStray 4 года назад +5

      My cat leaves muddy pawprints because she hops in the bathtub and laps puddles from the most recent shower. -_- I don't understand her. She has two water bowls and they're both clean.

  • @Shetasen
    @Shetasen 6 лет назад +1

    I remember when I saw the episode I was so confused but then I realized what the steroid was doing wasn't killing tissue which is what the buildings are but it was leveling the town. Earlier in the episode, in a very brief moment, the cells were screaming that the town was rising and getting pushed up because it was swelling.

  • @PigStuffy
    @PigStuffy 6 лет назад +94

    I wish there was more medical related anime, just so I can watch Dr. Hope review them!

    • @Moon1tan
      @Moon1tan 6 лет назад +3

      Ikrrr, there’s Dr.Stone manga but it’s more scientific than medical but it’s still great nonetheless ^^;;(it’s getting an anime next year tho yaaayyy)

    • @verifeli
      @verifeli 6 лет назад +2

      Try "Black Jack".

    • @lordofrims
      @lordofrims 6 лет назад +1

      Super Doctor K (manga) and Kusuriya no Hitorigoto (light novel and manga, it has more about old herbal medicine), and then pharmacy of another world (light novel and manga most of the time diagnosis and medicine creation and also the running of pharmaceutical industry)

    • @iamgeegee1258
      @iamgeegee1258 6 лет назад

      Like Black Jack

  • @mayneofgonz
    @mayneofgonz 6 лет назад +29

    Love the show, and love your explanations. While the show does a fantastic job, it’s great to actually discuss how it relates to real life. Please continue to review the show Doctor!

  • @Menace-To-Humanity
    @Menace-To-Humanity 6 лет назад +157

    *person watches cells at work* barely any views
    *an non anime watcher and doc watches cells* 1462694379937732 views.

  • @Malenrick
    @Malenrick 4 года назад

    What I like about the steroid is that it basically "stopped" everyone by attacking them but if you pay attention nobody is actually killed, so it's this shows way of showing how it's using extreme force to stop the reaction of the cells but as you said, isn't actually trying to kill them, but sadly can have some side effects and cause its own damage in its attempt to help.
    Obviously not 100% accurate and I'm not educated in any of this at all, but I caught that little detail while watching the episode myself, considering how "powerful" this medicine is, I was surprised it wasn't just killing the cells without issue and instead missing a lot, which led to this little theory of mine. Love this show and I love your reactions to it, your explanations just make it even better.

  • @sapphirII
    @sapphirII 4 года назад +1

    I feel like it's not necessarily a conspiracy theory from the memory cell, but more of a self-fulfilling prophecy.

  • @pyrauxe3507
    @pyrauxe3507 6 лет назад +34

    (Anime Release! Phoenix Wrightu no Jutsu!)
    *Slams Desk*
    What if the reason there were paw prints found on the picture which were confirmed to be of the defendant's cat was because it was the cat's picture all along, and his paw prints were his signature of the painting!
    ...GUILTY!

  • @Oshino.
    @Oshino. 6 лет назад +14

    I love the fact that you seem a little more excited with each one of these videos. Keep up the good work. Explainations and predictions are on point 😀

  • @shirophoenix01
    @shirophoenix01 6 лет назад +11

    The allergy episode was one of my favorite from this show. I suffer from seasonal allergy so I can relate to it. I must say though, Im currently taking an Anthropology class on Human Variation and we are discussing the Immune System and Cells at Work has helped me out so much because thanks to it I feel more prepared on this subject. Then with Dr. Hope's input it helps ingrain the info better. I really like the small drawing/cut-outs of the cells Dr. Hope uses to explain as it makes it easy to digest the info. Im a very visual learner so you have no idea Dr. Hope how helpful these videos are for me 😁👍🏻

  • @ahyes5625
    @ahyes5625 5 лет назад +26

    I need more memory cells in my brain...
    Now what was I talking about...?

  • @Pentium100MHz
    @Pentium100MHz 6 лет назад

    6:25 - the pollen does not cause damage, but maybe some cell saw it and did a damage report just in case ("well, it has not damaged anything yet, but I'm sure it will, better call the police/immune cells anyway", "HELP, the pollen is killing everything its path!") and then the immune cells overreact causing the allergic reaction.

  • @haltrei6525
    @haltrei6525 6 лет назад +14

    Apart from the amazing content and beautiful graphics of the anime, can we take a moment to appreciate those who create the subtitles~ the anime is so medical info-packed and as a translator/interpreter, medicine is such an intimidating field that I tend to stay away from 😂😂😂😂😂😂 the translator(s) of this anime really did a great job~

  • @rebeccacarroll9893
    @rebeccacarroll9893 6 лет назад +53

    Is it 12:30am where I live? yes. Do I plan to watch all 20 minutes of Dr. Hope geeking out and teaching me more about anatomy and physiology than I ever planned on learning? Also yes.
    P.S Was totally worth it, but now I really need to get to bed lol. Darn you Dr. Hope for your amusing and informative content! -shakes fist-

  • @alexisleskinen8623
    @alexisleskinen8623 6 лет назад +27

    I like this 20min format

  • @paularobles5441
    @paularobles5441 5 лет назад +29

    Now I understand what antihistamines really are and do

    • @Eguzkia57
      @Eguzkia57 11 месяцев назад

      That's esteroids: different from antihistamines 😊

  • @MrBadSmash
    @MrBadSmash 3 года назад +1

    I started watching Cells at Work with my daughter, and after we watch every episode, I come to your channel to get some extra depth explained about what's happening. I really enjoy your content, and after we finish Cells at Work, I'm gonna stay subscribed and check out your other work. Good stuff!

  • @redacted8983
    @redacted8983 6 лет назад +222

    I don't think Memory Cell is part of the T group. Kinda more like he's part of the B group. In the opening theme of the show, we see Memory Cell and B cell are together (go away, fujoshis. this for the sake of human anatomy I'm talking here) Which means, he's a Memory B Cell, but not a Memory T Cell

    • @DrHopeSickNotes
      @DrHopeSickNotes  6 лет назад +102

      You are right! A few people pointing this out. Thanks for clarifying

    • @Pangeroz
      @Pangeroz 6 лет назад +13

      You are right, later they will show us the Memory T Cell

    • @LuizAlexPhoenix
      @LuizAlexPhoenix 6 лет назад +21

      You say that like it matters to the fujoshi... It doesn't, they are hard at work with their doujinshis right about now.

    • @redacted8983
      @redacted8983 6 лет назад +4

      @@LuizAlexPhoenix Which kind of doujins? BL? That's the kind I despise them. Their BL doujin agenda

    • @aliefr2984
      @aliefr2984 6 лет назад

      @@redacted8983 yep, there are only 2 t cell, cd4 t cell/ t killer and cd8 t cell / t helper.

  • @Random1208
    @Random1208 6 лет назад +8

    Every time a practicing doctor looks up medical information on Wikipedia, an angel gets its wings.

    • @3lH4ck3rC0mf0r7
      @3lH4ck3rC0mf0r7 6 лет назад

      Any time a person practicing in a field looks up information about that same field on Wikipedia, an angel gets its wings.

  • @ashleyknight3959
    @ashleyknight3959 6 лет назад +24

    Yesss, can't wait for the cancer episode!!! This was amazinggg!!!

  • @mariakarinagandola3194
    @mariakarinagandola3194 5 лет назад +20

    The fact that he's just smiling everytime😂😍 Our doctor is really enjoying it hahahahah

  • @luckily_iam1167
    @luckily_iam1167 5 лет назад +1

    I am a medical laboratory science student and watching "cells at work"+you(doctor) expanding the topic, helps me prepare for my upcoming exam in immunology & serology. Haha thank you Dr!

  • @ShrooMIR05
    @ShrooMIR05 6 лет назад +64

    The king of youtube is back

    • @DrHopeSickNotes
      @DrHopeSickNotes  6 лет назад +9

      Yuri Yuki THAT’S RIGHT! Let the feast of learning commence!

  • @lillyofthenorth8798
    @lillyofthenorth8798 6 лет назад +12

    Yay! New episode. Thank you for these! I'm currently in Alaska still recovering from the recent earthquake, and this is really helping my morale stay up. Perfect timing

  • @Pobblí-v3w
    @Pobblí-v3w 6 лет назад +30

    I had a hive (urticaria) breakout one time and the way the episode demonstrates medication use for mild to severe allergies (such as hydrocortisone or a higher potency such as methylprednisolone) makes me feel a bit bad for my own cells in my body. Really important to stay hydrated and relaxed too. ;)

    • @KitZunekaze
      @KitZunekaze 6 лет назад +3

      To be fair the representation of a steroid like hydrocortisone was a bit exaggerated in this episode, as well. But it fit a theme of over-exaggeration being the problem. A cool thing with the show, though, is you never hear about the body but if they're getting steroids for a standard pollen reaction, they must have had a very severe reaction and possibly even ended up in the hospital. Otherwise much less potent medicine would have been fine.
      Dr.Hope explains a steroid better than I could, but they don't cause as much collateral damage as represented in the anime.

  • @Karichi15
    @Karichi15 6 лет назад +27

    Sick person: “Are you a doctor?”
    Me: “No but I watched this cool anime so I’m totally certified for this”
    Reminds me of “You can fly a plane?” “No but I’ve played multiple videos games so I got this”

    • @anatamistress8826
      @anatamistress8826 5 лет назад +3

      You know...I'm something of a scientist myself

    • @emalynscott7612
      @emalynscott7612 5 лет назад +3

      "Have you gone to flight school?"
      "I took a crash course."

    • @red2theelectricboogaloo961
      @red2theelectricboogaloo961 4 года назад +1

      you know, i'm something of a doctor myself.

    • @sharlisify
      @sharlisify 3 года назад

      There is a story that goes around that this actually happened, something happened to him and the person who said he could fly the plane, found out after the incident he learned playing flight simulation 🤣

  • @kazaki03
    @kazaki03 5 лет назад

    Thanks for reviewing this episode! As a sufferer of allergic rhinitis for more than a decade, it really made me feel better. Antihistamines are my saviors but yknow, they make me sleepy.
    It sucks having allergic rhinitis bec it's difficult to do things such as touching dusty things, hugging teddy bears, too much face powder, perfumes, and other things. I love how this episode covers the whole process for the non-medical people to learn. Very educational!

  • @TitheGirl
    @TitheGirl 6 лет назад +20

    I feel like I’ve been waiting for this episode forever!
    (I sneezed due to allergies three times while writing this 😂)

  • @Taicligh
    @Taicligh 6 лет назад +15

    I can't even finish the anime until he makes a video about the episode so that I fully understand what happened, lol. Well worth the wait though and about the only time I'm like BUT EDUCATION I need to know!

  • @istoleyourwalletwhileyouwe3356
    @istoleyourwalletwhileyouwe3356 6 лет назад +84

    oh my god, he has a cat.

    • @DrHopeSickNotes
      @DrHopeSickNotes  6 лет назад +11

      This is the culprit:
      instagram.com/p/Bq1uwGsBz1Z/

    • @nijnij3988
      @nijnij3988 6 лет назад +2

      @@DrHopeSickNotes Ahww, she's so beautiful! I guess she just wanted to learn about antigens too :)

    • @kinghadbar
      @kinghadbar 6 лет назад +5

      Ovaries explode.

  • @chevimae
    @chevimae 4 года назад +22

    The host of this body, for me, would definitely be a military man/woman or someone in the force, could be a police as well. They could also be a travel journalist or someone who studies the wild like Bear Grylls because damn the host has been through a lot...

  • @clericneokun
    @clericneokun 6 лет назад +31

    "Every story benefits from a terminator with a minigun."
    Best medical advise I've heard all day! 👍

    • @joshgellis9463
      @joshgellis9463 5 лет назад +2

      clericneokun 'advise' is used in caution: such as: "advise me, sir." 'advice' is the correct word you're trying to spell: "what's your advice?" referring to giving beforehand information.
      it may not seem to have a difference, but there IS. *_LOL_*
      *_Future Teachers At Work_*