THANK YOU everyone for all the support of this series. This was my favourite episode to date, in terms of medicine it was crazy how much stuff there was and was good immunology revision for me! Apologies for the audio at the start of this one, it does improve. Let me know your favourite episodes down so I know what I've subjects I've got to look forward to...
I knew you would LOVE it -- the episode that made me really realize how brilliant this series is in terms of how it delivers it's story in the human body.
" I didn't want to make this video an hour long" Why do you think I'm here? Are you implying that I wouldn't sit here for the whole ride if you did make a longer video?
When Macrophage swings her knife and the aerial shot shows her skirt flowing in a circle, it makes her look like the actual cell. Just a nice detail I noticed.
A Doctor reviewing an Anime about Cells and the Human Body, who could have guessed this would be such an absolutely wonderful series? Thank you so much!
Cells At Work: *stuffs so many medical easter eggs into the background that you come to expect them* Also Cells At Work: "I just thought it'd be funny for a badass to lose his shoe."
You know the video is going to be good when you have: 1:Anime; 2:Science; 3:A charismatic person who knows what he's talking about. Awesome video as always! I'm waiting anxiously for the next one!
By stopping the video and breaking down the different medical terms in the show you create something amazingly entertaining and Unique. These visual break downs are really the highlights of each episode!!!!
I agree. Similar to how I love reading the manga because it’s harder to pause a stream to read than to read a caption over. Especially since there are captions they don’t really pause for.
@@Kai-vo5zq Usually a weeb claims to know Japanese despite not knowing anything about the language at all, so that's probably why they were called one in the first place
13:26 "In reality, this would happen slightly differently".. Right, I imagine my dendritic cells would speak English, and not Japanese. I think it is still close though!
Not really looking for reaction channels, but a professional doctor watching an anime I like and takes time to explain facts and other comments about the show is very nice
Half the fun of these videos is watching someone who can pick up all the "in-jokes" with glee. It's a good show, and it's almost a shame that most of the attention to detail would be lost on the common viewer without some help. On a separate note, how unlucky is this person to get infected with two strains of influenza one after the other?
What a great question! I’ve had a think for a few minutes and I can’t think of an example either way that would steer my guess... vast majority in bacterial infections we grow one main bug when we culture. So I’ll throw it open to the community!
@@bromora989 weeell there IS a spin-off of Cells at Work! called "Cells at Work: Black" where in this spin-off its shows what kind of bacterias would infect us if we don't properly take care of our body and live in a unhealthy lifestyle Also I liked the fact that the main casts are gender bent
@@DrHopeSickNotes There is a spin-off of Cells at Work! called "Cells at Work: Black" where in this spin-off its shows what kind of bacterias would infect us if we don't properly take care of our body and live in a unhealthy lifestyle Also I liked the fact that the main casts are gender bent
I don't know what I love more: The doctor analyzing an anime, or just his sheer delight at it. This is super fun to watch and look forward to more of your reviews. This takes "anime reviews' to a whole new level, AND it's educational!
What I enjoy, besides both of those things you mentioned, is how Dr. Hope segues into a simple biology lesson. Like HOW a virus is able to enter a cell and all the things that happen after. I feel it's easier to learn when both teachers and students are both enthusiastic about the topic.
@@madpinoy5683 Exactly. It's not that I dislike a subject. I just absolutely despise the way people are unenthusiastic or teach in the most boring way possible and expect me to be invested.
Hello, I am a Japanese student. Many Japanese feel joy in his introducing a Japanese animation with a smile such happily. I want him to enjoy animation of Japan from now on.
ソラ... I am 40 years old, American male. I discovered the wonder of Japanese animation and manga, at the age of 8 years old. My first was "Nausicaä of the Valley of the Wind" played in theaters (sub titled) in 1985. It was the true version and not the modified for Americans version. From then on, I have enjoyed the amazing work from so many wonderful artists. Thanks from a silly "old" American for sharing such beautiful, enjoyable, and entertaining work with the rest of the world. I for one say this world would be far worse off with out it.
Exam Question: How does the immune system fights off viruses? Answer: A hot macrophage slaughters the viruses with an axe. Then the macrophage rips out the antigen with her bare hands and reports it HQ.
Well, it's not so fatch off. The difference is that the macrophage EATS the viruses and then shows the antigen to HQ (which is called helper T-cell). Then the helper T-cell calls off T-killers and B-cells, as well as more macrophages and neutrophiles.
Podemos URSS Macrophages, Neutrophils, Monocytes and Eosinophils do EAT the germs and virus as phagocytosis in the show. They cook them in pot, made them into stew and then eat them. If they cannot finish them, they use enzymes to dissolve it
The Japanese word for Dendritic cell actually means "tree-appearance cell" too and it's fitting they have his office thing shaped like a tree. I'm guessing you'll be doing more in the future.
I really wouldn't mind getting a biology lecture for this show in 1 hr tbh... I love the whole "how influenzas/viruses infects ordinary cells" education. I thank you for that. 👏🙌
Being a biology major in college, this anime and these videos are actually really neat to watch. I always loved learning about these types of things, and being someone who really enjoys anime as well makes these videos a nice way to learn about our immune system and how it really works. Keep up the good work man, both as a doctor and with these videos! Can't wait to see more of your work.
Same! I was a bio major (intending to go to vet school, but the physics component knocked me out x_x) I love these breakdowns. It's like RUclips Magic Schoolbus
Am also a bio major. I first watched the series during my Term 2 and it helped me quite a bit, but now that I'm rewatching it at Term 4 I'm beginning to understand more and more of the references and Dr Hope's explanations. It's amazing!
"Hello this is Dr Hope... I say that even knowing I've gained 400 lbs, a neckbeard, and dropped out of medical school, but here is my analysis on episode 642 of One Piece"
"This is what it's like when you start life as a Junior Doctor" Just now envisioning a ward full of killer consultants and physicians ganging up on you Doc 😂
Doc, I'm actually cool with you making a separate video where you can do an in-depth explanation about all the things that you're holding back in this ep! I'm really interested if you can do one!
Been here since Episode 1's reaction video, what a great series. Even though I'm an IT undergrad myself, I love the way you explain the bio stuff in the show. This is the best rewatch of Cells at Work I could've ever hoped for lol.
Hello! I am Japanese. I have seen all this story with this animation, but indeed I was really interested in what kind of reaction the doctor actually would show this animation. As a result, I found a video that translated your movie into Japanese. When I looked at it quickly, I saw your figure that explained my doubts very easily. I looked for your channel soon and registered. I do not quite understand English, but I am happy watching your videos. Please keep doing a good job.
Yipi Yayo No it isn't. In the beginning of that sentence "In Japan, it was fun because there was no movie explained like you." So, if you were add Japan again, it would be grammatically inaccurate.
*Viral Infections* are one of the most interesting concepts in Biology to me. It's like a very tactical war; Invasion and sending in double agents (Cells infected by viruses) to destroy from the inside. It's so damn cool and smart considering Viruses don't have a brain or anything, yet seem so tactical. Love your vids as always! :)
It's not that surprising, evolution creates things that work, so with the length of time viruses and cells have ben going at each other it makes sense that what has developed gives the appearance of intelligent tactics, because intelligent creatures also develop tactics that work. Still cool though.
Stupid question: does a virus, bacteria, or fungi have DNA? I've read somewhere that DNA has instructions in it that cells follow in order to do what they do. So maybe what they have is like... instinct? Virtual Intelligence?
if I remember correctly I think there's some thought or evidence that viruses were developed by bacteria ages ago as a weapon but since viruses are imperfect replicators they are subject to the process of evolution. Fun fact: the reason why mammals carry their young inside is because our line was infected with a retro-virus that prevented our eggs from being laid.. so we evolved a way around the issue.
You should check out the RUclips channel Journey to the Microcosmos if you have any interest in stuff like that. It’s absolutely brilliant. Imagine Bob Ross meets BBC nature documentaries, but about microorganisms 🦠
TheSleepysleep I would like to do that. My focus however, is Elementary Education- so I sincerely wish I can program young minds. Somebody, a teacher NEEDS TO REACT to Anime Teachers doing their jobs!
Well that explains Dendritic Cell's hat medallion and why it lives in a tree, and even that sprig in the buckle. This anime has such meticulous details but doesn't overwhelm the main points of the story with them. Simply adds to the World if you look hard enough! This is why this series you're doing is so wonderful, you're giving basic and easily consumed explanations that allow non-biology majors to enjoy this show at its full artistic scale.
After this series, please do make a reaction to the show's spin-off manga, Cells at Work Black. It takes a dark (and quite morbid) turn where the cells are working in a very unhealthy body and face very harsh challenges in doing their jobs.
It's enough to put me off smoking and alcohol for at least another year. It's (quite literally) sickening what people do to themselves without considering the effects these substances can do when consumed in excess. Ughhh...
What's up Doc! I hope you've noticed easter eggs in this anime. Like when the red blood cells have no oxygen their red clothing is darker. There are other things, but I think it's best to let you find out on your own. lol As an MA myself, you being a doctor and reviewing this anime is the greatest thing. Haha
wait I never noticed that the red blood cells had darker clothes without oxygen >.> guess I need to rewatch it all and make sure I see everything kappa
@@biffnotsotannen1462 Yeah, watch for the little details. Like the fact that the platelets are kids. He did explain why they're kids last video. But if you actually know the details about platelets, you'll realize why you never see any teen/adult platelets ;-; again, the little details. Haha
The absolute input you have on this and the context you provide with not only medical information but how you can relate all of this with your own career and life choices that led you down this path is absolutely astonishing. Well done god sir, you have made me an avid fan
On the one hand, as a teacher, am pleased as punch that that so many biology classes are jumping on this series as a teaching tool to make learning more fun and engaging. On the other hand, as a MATH teacher, I'm a little perturbed that Biology is SUDDENLY everyone's favorite class now that they get to watch Anime for their freaking lecture. When are they gonna make an Algebra Anime, dangit!?
Cadet Grey oh daamn, yeah, you should study then xD I have around half a year until my final exams of college (I‘m always unsure if the german gymnasium is college in englisch but I think so?) xD that next week is just a „normal“ one xD
"I dont eant to make this an hour long" pLEASE MAKE IT AN HOUR LONG, THIS IS BETTER THAN MY CLASS LMAO. Hopefully you'll make a new vid reacting to this, take care!
I love the timing so much. Literally when Cells At Work finished airing I just started college. I go to a science college so literally everything here is important to my education XD. My favourite part is when the lecturer talked about how "Neutrophils would hunt down pathogens as if they have nothing else to do" then all the weebs in my class just started laughing like crazy... Then she told us that white blood cells often die while fighting an infection and we were like: Oh. ._.
The thing I like about this series is the fact that you don't stray from what your channel is about. You react and at the same time teach biology in simple terms. I have learned so much and remember it compared to taking a whole year of it in my sophomore year. I'm also glad you are enjoying it and not just milking this series.
I am a Japanese listener. I was impressed watching your videos. You might already know, in fact the color of the red blood cell jacket is slightly different when it is in the artery or in the vein! According to the official setting, the jacket seems to be reversible.There is a fine ingenuity. Please watch it carefully. Sorry for my bad English (T_T)
@@araragisenpai4088 I am so happy to be able to connect with people all over the world through Japanese animation. I expect the sequel of this video series. I'm a senior high school student,but I want to communicate with foreign people more,so I'll study English. Thanks for your comment !
I find the question of whether to treat the fever or not to be rather interesting. It's something I never thought about as one would typically see the fever as the problem instead of a side effect to your body trying to fix the actual problem.
Yeah, you don't often think about it that way. I kinda thought the fever was caused directly by the virus and not to fight it. Knowing that's what the fever's there for, I'd probably actually prefer to keep the fever. If you're an adult - and not someone with a weak health in general - it shouldn't be that hard to deal with a fever. After all, you turn in sick from work when you get the flu, so you just have to lie on your couch and make sure to drink a lot of water/tea/juice/etc. to keep hydrated. If it helps slow down the virus a fever might actually mean that you'll get back on your feet faster?
It's also kinda like when you have a fracture or injury and one of the body's first response is inflammation which promotes healing to the injured site. And it also has the interesting question on whether inflammation should be reduced by using medication and ice packs. I think that in very severe cases where inflammation may damage surrounding muscle and nerves is when I think medication should be used. So I think it's quite and interesting question. ^.^
Well please do longer! I prefer hearing your teachings. More in depth. Really enjoyable. I love biology and your explaination feels sort of first love all over again! I would turn on yours and just listen whilst sketching on my desk ❤❤❤
1:18 I think the shoe falling off is just showing how the white blood cell's ability to transmigrate. They can slip through even the narrowest cracks. That's why the shoe got stuck. It's so quirky.
Me watching educational videos then got recommended with the episode 1 of this series,... One hour later, I had watched three of them,... conclusion : Dr. Hope is the best internet / RUclips doctor. Good job doctor. p.s: subscribed, commented, and shared.
@@BmacSoundsLab anime is 2d animation therefore it is also cartoons. It's just a sub genre that can stand on its own enough that people can forget that fact.
More like cartoon is a sub genre of animation. Cartoons are typically associated with a very different distinct style that is more focused on the younger population. What you say is only true for Japan, outside Japan anime refers to a very specific style made by the Japanese.
I studied Biomedical Science in University, and I loveeeee anime A LOT. So I can't say how much I LOVEEEE this anime! Watching your videos makes it even better! The things you went through were exactly the things I had learnt in University, but of cos, it's just on the surface. But nonetheless, it's an enjoyable and knowledgeable series! Really hope you can share more information 'cos I really love learning new facts or even just refreshing my memory about our body systems, and you make Biology looks even more interesting too! I love how you look so passionate when explaining all the information to us! Kinda motivates me even more! (x Keep up the good videos! (((:
I just realized that Macrophages wear a maid's uniform, colored white. Because they clean up dead things in the body, and carry a hatchet, a simple but effective weapon.
That shot of her from above is actually some really smart cinematography. Shot in the Dark but her dress seems to be her cytoplasm while her head is her nucleus. In comparison to other cells, macrophages have far more cytoplasm in comparison to their nucleus than their white blood cell cousins.
The Macrophage carries a hatchet, while other immune cells carry knives, because macrophages are large ("macro") enough to kill multiple pathogens at a time, while others are only able to kill one at a time.
2:39 omg that’s so funny! Literally last week (I’m a high school student btw) my biology teacher did a thing with us about viruses and about how their neither alive nor nonliving
"I didn't want to make this an hour long..." I'll be down for that. Possibly have one episode within the 20 minute mark and other be an extended version of that with uncut educational content. Sign me up
I made my mom watch Cells at Work! today, and for the first time in 20 years, she said that anime has finally done something beautiful and educational xD
I wish we had this anime and reactions from you 4 years ago during my virology and immunology classes 😢😢 I never understood transcription and translation....and just from this video and your explanations....I'm here screaming "I get it now!" 😅😅😅 thanks a lot doc! Another great video!
After you did the second episode I was already pretty much sure that you HAVE to do the entire anime, for a good reason! That's the most entertaining "react" series I have ever seen, simply because it's just not a guy watching at a screen overreacting to everything he sees without giving any other input, yours are educative and Fun to watch!
This is fantastic, especially for visual learners. I love how you break it down in between with drawings and rubber bands, bits and bobs. It really helps relate the mechanisms on the most basic level, instead of just reading words in a book.
Learning your body From book = Normal mind From education video = Wowing your mind From Cells at work =Amazed your mind Doctor react to Cells at work = Blow your mind
you could just watch 'em all at this point. the ongoing a-plot might interest you after all, even if you're too busy digging out medical facts instead of paying attention :p
Can't count how many times I went "OHHH, so that's why x happens to my body!" And after hearing how my cells work, I now feel my cells are smarter than me. T.T I've finished the anime season but it's fun to rewatch it with expert commentary. Thank you, Dr. H!
Cells At Work is already an educative series but you help elaborate it further, and I may not pursue medicine but I’m so fascinated and grateful by your breakdowns for each episode. I enjoy it so much. Thank you so much for helping us learn more.
More Cells at Work, more Dr. Hope, more learning! Yay~ 17:40 I would love to hear a one hour lecture and an extended explanation in detail to be honest
You need a doctor's degree and at least some work experience in order to have a final-tier position in the medical field. This particular field is notorious for being pricey, lengthy, and rigorous even before a doctorate's program. Thus, one should only major in it with genuine passion and interest, not merely on a whim. I believe Jonathan believed OP was thinking on a whim, which could prove to be a costly mistake in money and time. I took 3 years of medical in high school for EMT myself and decided to switch because memorizing 500 root words and other medical symbols/jargon as a "small warmup" of what's to come just wasn't worth it for me.
it's tough as you basically have to know everything. But it's fine if you love it. A piece of advice if you really want to pursue medical career, be strong and never give up. It can be stressful and busy and sometimes you'll be scolded (the doctors can be very strict to their students). You have lesser vacations too. But if you enjoy it, everything will be fine.
![BLACK BAG - Official Trailer [HD] - Only in Theaters March 14](http://i.ytimg.com/vi/Du0Xp8WX_7I/mqdefault.jpg)
THANK YOU everyone for all the support of this series. This was my favourite episode to date, in terms of medicine it was crazy how much stuff there was and was good immunology revision for me! Apologies for the audio at the start of this one, it does improve. Let me know your favourite episodes down so I know what I've subjects I've got to look forward to...
You earned it. It's fun seeing you watch this and how much you genuinely enjoy explaining things. You're such a nerd, haha.
Next: The allergy episode! 😁
Keep It Up, Doc! XD
Before you disappear someone told me about why Red Blood cell keeps getting lost! She's a sickle cell! Her hair is the clue.
I knew you would LOVE it -- the episode that made me really realize how brilliant this series is in terms of how it delivers it's story in the human body.
" I didn't want to make this video an hour long"
Why do you think I'm here? Are you implying that I wouldn't sit here for the whole ride if you did make a longer video?
Ikr!
Exactly!
Everyone hurry and like elevate07's comment so Dr. Hope can see how much we are all in agreement on this issue.
yeah..he should just make it AT LEAST 30minutes. the las part where antibody was coming also should be reviewed.
بالضبط ! I KNOW RIGHT AGH🔥💜
When Macrophage swings her knife and the aerial shot shows her skirt flowing in a circle, it makes her look like the actual cell. Just a nice detail I noticed.
the people of this anime are quite clever with their designs
I love her she looks like the next Disney badass princess !
She is also cleaning large amount of the virus/bacteria hehe why she looks like a maid :3 or at least that's what I thought was cute lol
Yea yea we noticed
Thats not a knife thats a Hachet
Like the hats all the red blood cells wear.
A Doctor reviewing an Anime about Cells and the Human Body, who could have guessed this would be such an absolutely wonderful series? Thank you so much!
Bryce Mckenzie it's the kind of thing I didn't know I needed in my life, but now that I saw it I do
Cells At Work: *stuffs so many medical easter eggs into the background that you come to expect them*
Also Cells At Work: "I just thought it'd be funny for a badass to lose his shoe."
It happens because of migration into very small places
You gotta love the mix of medical education and hilarity in this XD
And they were right to!
Nobody:
Dr. Hope: dancing to the CaW intro
@@ruthsevere8128 just waiting till he cosplays 😆
We live in an age where the question "what's your favorite cell" has become incredibly commonplace.
Mine's Macrophage.
Mine too. Majestic and deadly.
Yandere mode
NK Cell is bae
Platelets...... im weird
(DONT ASK WHY)
Macrophage is best cell.
You know the video is going to be good when you have:
1:Anime;
2:Science;
3:A charismatic person who knows what he's talking about.
Awesome video as always! I'm waiting anxiously for the next one!
Yep!
Totally ^^
true
YASS
Agree👍
By stopping the video and breaking down the different medical terms in the show you create something amazingly entertaining and Unique. These visual break downs are really the highlights of each episode!!!!
I was going to say this same thing!!! I think it is so extremely helpful!!! I love getting to learn more in such a fun way!
Same. I usually hate when people pause the video to stop and talk on reaction videos but this is one exception to that.
I agree. Similar to how I love reading the manga because it’s harder to pause a stream to read than to read a caption over. Especially since there are captions they don’t really pause for.
T cell before: I am weak
T cell after: I am JOJO！Oraoraoraora！！！！
Killer T Cell is voiced by Daisuke Ono (Jotaro Kujo), and Effector T Cell is Voiced by Kenji Nomoura (Santana)
MUDAMUDAMUDAMUDAMUDAMUDAMUDA
Also Erwin Smith and Drole
Same studio.
Thought so too lol
*Looks at cell biology notes in my hand* I think i have a better idea, *opens up youtube and comes here* TEACH ME SENPAI!
TheWandering Ordeal I actually took on the anime lmao
Thats sensei not senpai weeb
@maki kuzu lol. The fact that you answered that, wouldn't that make you the weeb?
@@Kai-vo5zq Usually a weeb claims to know Japanese despite not knowing anything about the language at all, so that's probably why they were called one in the first place
@@Panpea ey, you right
mission "turn a doctor into an anime youtuber" shows great succes
BLUE SKULL Good work, comrade. *Applause surrounds all of us*
@@NightmareVixen12art may the jiggle physics be with you comrade
BLUE SKULL and to you too, comrade
@@NightmareVixen12art thanks comrade
Tbh, he's better than most anime RUclipsrs right now, quite a few of them have been dropping in quality drastically as of late.
When the naive T. cell matures it looks a Pokémon mega evolving
Especially since it turns back...
And evolves into a Jojo
@@Rupi1234ful To be fair, Santana is the Effector T Cell, just as the (Memory) Killer T is Jotaro and the Helper T is Rohan.
I looked at your pfp and understood completely
@@Rupi1234ful And does an ora rush.
13:26
"In reality, this would happen slightly differently".. Right, I imagine my dendritic cells would speak English, and not Japanese. I think it is still close though!
Right, I think our cells speak english than spreading chemicals to communicate
maybe it depend on someone body lol, if it is a dog system they will bark while communicate 😀
So good, seriously thank you for making more of this series.
Hahaha!
I would say they speak chemical.
You know you're a nerd when your favourite reaction series is a doctor reacting to an educational anime.
Edward Hahm No... A TRUE NERD like me
I mean, it’s cool that somebody is breaking down the episode while enjoying it, right??
Not really looking for reaction channels, but a professional doctor watching an anime I like and takes time to explain facts and other comments about the show is very nice
Banana Senpai either that of a med student (like me)
I CAN RELATE TO THIS SO MUCH HAHAHAHAH
Half the fun of these videos is watching someone who can pick up all the "in-jokes" with glee. It's a good show, and it's almost a shame that most of the attention to detail would be lost on the common viewer without some help.
On a separate note, how unlucky is this person to get infected with two strains of influenza one after the other?
What a great question! I’ve had a think for a few minutes and I can’t think of an example either way that would steer my guess... vast majority in bacterial infections we grow one main bug when we culture. So I’ll throw it open to the community!
Psychronia I myself was thinking: damn, this person gets ill a lot.
@@bromora989 weeell there IS a spin-off of Cells at Work! called "Cells at Work: Black" where in this spin-off its shows what kind of bacterias would infect us if we don't properly take care of our body and live in a unhealthy lifestyle
Also I liked the fact that the main casts are gender bent
+InfernoHomura wait i heard they show HIV or AIDS in that spinoff....am i right?
@@DrHopeSickNotes There is a spin-off of Cells at Work! called "Cells at Work: Black" where in this spin-off its shows what kind of bacterias would infect us if we don't properly take care of our body and live in a unhealthy lifestyle
Also I liked the fact that the main casts are gender bent
I don't know what I love more:
The doctor analyzing an anime, or just his sheer delight at it. This is super fun to watch and look forward to more of your reviews.
This takes "anime reviews' to a whole new level, AND it's educational!
What I enjoy, besides both of those things you mentioned, is how Dr. Hope segues into a simple biology lesson. Like HOW a virus is able to enter a cell and all the things that happen after. I feel it's easier to learn when both teachers and students are both enthusiastic about the topic.
@@madpinoy5683 Exactly. It's not that I dislike a subject. I just absolutely despise the way people are unenthusiastic or teach in the most boring way possible and expect me to be invested.
Hello, I am a Japanese student.
Many Japanese feel joy in his introducing a Japanese animation with a smile such happily.
I want him to enjoy animation of Japan from now on.
ソラ... I am 40 years old, American male. I discovered the wonder of Japanese animation and manga, at the age of 8 years old. My first was "Nausicaä of the Valley of the Wind" played in theaters (sub titled) in 1985. It was the true version and not the modified for Americans version. From then on, I have enjoyed the amazing work from so many wonderful artists.
Thanks from a silly "old" American for sharing such beautiful, enjoyable, and entertaining work with the rest of the world. I for one say this world would be far worse off with out it.
I am a perfect human
Many english-speakers love Japanese Animation, and I'm among those, count us in!
FUCKING WEEEEEEBS! (ha jk I rather enjoy anime and have also read plenty of manga's and a few light novels here and there)
We are still so disconnected from the eastern part of the world
Hi from Chile!
"This is pretty much what it's like when you start your life as a junior doctor" LMAO
Exam Question: How does the immune system fights off viruses?
Answer: A hot macrophage slaughters the viruses with an axe. Then the macrophage rips out the antigen with her bare hands and reports it HQ.
Dont forget the smile which indicates a true passion for the job that the Macrophage was charged to do 👍
Well, it's not so fatch off. The difference is that the macrophage EATS the viruses and then shows the antigen to HQ (which is called helper T-cell). Then the helper T-cell calls off T-killers and B-cells, as well as more macrophages and neutrophiles.
They eat them in later episodes
Oh my god 🤣
Podemos URSS
Macrophages, Neutrophils, Monocytes and Eosinophils do EAT the germs and virus as phagocytosis in the show. They cook them in pot, made them into stew and then eat them. If they cannot finish them, they use enzymes to dissolve it
The Japanese word for Dendritic cell actually means "tree-appearance cell" too and it's fitting they have his office thing shaped like a tree. I'm guessing you'll be doing more in the future.
Wow 🤩 i like how this anime is so accurate
I googled it and found that dendrites actually means "tree-like" derived from the greek word dendros "tree"
I mean... thats what dendritic means too... so...
Nice note
And that’s why in Genshin Impact Dendro users often summon green flowers basically any nature themed attacks excluding the traveler
I really wouldn't mind getting a biology lecture for this show in 1 hr tbh... I love the whole "how influenzas/viruses infects ordinary cells" education. I thank you for that. 👏🙌
Suddenly it makes so much sense why the Dendritic cell lives in a tree.
I noticed that right away. Then again, I love puns.
Of course, that implies that the Dendritic cell we see is actually a single activator and its actual body is the entire tree.
Also if you look at the symbol on his cap it is similarly shaped. Just love this anime and the attention to detail.
Being a biology major in college, this anime and these videos are actually really neat to watch. I always loved learning about these types of things, and being someone who really enjoys anime as well makes these videos a nice way to learn about our immune system and how it really works. Keep up the good work man, both as a doctor and with these videos! Can't wait to see more of your work.
Same! I was a bio major (intending to go to vet school, but the physics component knocked me out x_x) I love these breakdowns. It's like RUclips Magic Schoolbus
Am also a bio major. I first watched the series during my Term 2 and it helped me quite a bit, but now that I'm rewatching it at Term 4 I'm beginning to understand more and more of the references and Dr Hope's explanations. It's amazing!
"But I didn't want to make this video an hour long."
I would watch. The entire. Hour.
Twice?
@@ZenoDLC Thrice!
I. Wouldn’t. Even. Notice
Oh yes I would too!
i've watched longer ones before
Nice we turned a doctor into a weeb
Lmao
"Hello this is Dr Hope... I say that even knowing I've gained 400 lbs, a neckbeard, and dropped out of medical school, but here is my analysis on episode 642 of One Piece"
but he only does medical related videos so he probably would dont even care about the anime thats not about medical science
Yesss lol
HAAHAA
"This is what it's like when you start life as a Junior Doctor"
Just now envisioning a ward full of killer consultants and physicians ganging up on you Doc 😂
Am I the only one who's excited for the Cancer Cell episode?😁
Mar Nitsuga No, u r not the only one. Haha
Same! I'm really hoping he makes a long episode for it too.
30 minutes or more would be great!
Mar Nitsuga cancer cell is kinda depressing
I WISH IF THEY COULD MAKE ONE TO HIV TOO
One detail I love is how, any time the problem is one of the body's own cells gone bad, Neutrophil U-1146 is shown doing a Shinto prayer for the dead.
Doc, I'm actually cool with you making a separate video where you can do an in-depth explanation about all the things that you're holding back in this ep! I'm really interested if you can do one!
Me too!! I would be interested!!
Same
Same!
Please do make vid of it too!!
Been here since Episode 1's reaction video, what a great series. Even though I'm an IT undergrad myself, I love the way you explain the bio stuff in the show. This is the best rewatch of Cells at Work I could've ever hoped for lol.
i know right I keep smiling and laughing and
"IT undergrad", lol, *highfive
Hello! I am Japanese. I have seen all this story with this animation, but indeed I was really interested in what kind of reaction the doctor actually would show this animation. As a result, I found a video that translated your movie into Japanese. When I looked at it quickly, I saw your figure that explained my doubts very easily. I looked for your channel soon and registered. I do not quite understand English, but I am happy watching your videos. Please keep doing a good job.
Can you share where the video translation to Japanese is? Is it on ニコニコ動画? I always hear about it but I don't know where to look.
xeshirem try searching for sm33980216
Narumo LuckyCarrot Thank you. I understood the meaning of the question with your comment. I think that you can search ニコニコ動画 for IDs in his comments.
Glad I could help :)
Narumo LuckyCarrot
I am a Japanese who likes cells that work. Your video is clear and amazing. In Japan, it was fun because there was no movie explained like you.
Slight correction. "It is fun because there was no movie explained like you in Japan."
Yipi Yayo
No it isn't.
In the beginning of that sentence "In Japan, it was fun because there was no movie explained like you."
So, if you were add Japan again, it would be grammatically inaccurate.
He is a movie
@@zeenalyounsi8844 yeah, it's actually "it was fun because there was no movie explained like you did" or similar
This video is in hot ranking 16 in Japan now!
You are so popular all over the world!!
wow
I've never enjoyed a biology class before. Now i do
Same, it's really informative
Indeed
Yep. Dreaded bio when I was in school, but this doctor seems to make it extremely interesting
same. this guy should've been my teacher. school would've been way more interesting that way
If my HS Biology teacher was not so boring I would of never skipped her class
*Viral Infections* are one of the most interesting concepts in Biology to me. It's like a very tactical war; Invasion and sending in double agents (Cells infected by viruses) to destroy from the inside. It's so damn cool and smart considering Viruses don't have a brain or anything, yet seem so tactical.
Love your vids as always! :)
Genetic molecules are mind-boggling.
It's not that surprising, evolution creates things that work, so with the length of time viruses and cells have ben going at each other it makes sense that what has developed gives the appearance of intelligent tactics, because intelligent creatures also develop tactics that work. Still cool though.
Stupid question: does a virus, bacteria, or fungi have DNA? I've read somewhere that DNA has instructions in it that cells follow in order to do what they do. So maybe what they have is like... instinct? Virtual Intelligence?
@@rolandaustria7926 Viruses are kinda like machines. They have a set of genetic instructions and they follow it. Its that simple.
if I remember correctly I think there's some thought or evidence that viruses were developed by bacteria ages ago as a weapon but since viruses are imperfect replicators they are subject to the process of evolution.
Fun fact: the reason why mammals carry their young inside is because our line was infected with a retro-virus that prevented our eggs from being laid.. so we evolved a way around the issue.
Imagine being the first person to see microorganisms. "I'm not 100% sure what I'm looking at, but this shit is wild!"
You should check out the RUclips channel Journey to the Microcosmos if you have any interest in stuff like that. It’s absolutely brilliant. Imagine Bob Ross meets BBC nature documentaries, but about microorganisms 🦠
TheSleepysleep I would like to do that. My focus however, is Elementary Education- so I sincerely wish I can program young minds. Somebody, a teacher NEEDS TO REACT to Anime Teachers doing their jobs!
@@Tinyvalkyrie410 ooohhhh! Thanks for the recommendation!
TheSleepysleep if you do end up checking it out I would love to hear your opinion. It’s currently my favorite channel on RUclips
Oh my god. The Dendritic Cell's Base of Operations is a treehouse...
Its a nice and cute reference to the 'branched' shape
AHAHAHAHAH you are everywhere
Welcome back mustacho
Just Some Guy with a Mustache basically you pop up where ever anime comes up, even if it is boring science 😆
kita!
Well that explains Dendritic Cell's hat medallion and why it lives in a tree, and even that sprig in the buckle. This anime has such meticulous details but doesn't overwhelm the main points of the story with them. Simply adds to the World if you look hard enough!
This is why this series you're doing is so wonderful, you're giving basic and easily consumed explanations that allow non-biology majors to enjoy this show at its full artistic scale.
Watched Cells at work, and now I'm watching this guy watch cells at work
same lol
After this series, please do make a reaction to the show's spin-off manga, Cells at Work Black. It takes a dark (and quite morbid) turn where the cells are working in a very unhealthy body and face very harsh challenges in doing their jobs.
It was so dark and depressing but it became so good.
as someone with chronic health issues, sign me the f up for THAT one
It's enough to put me off smoking and alcohol for at least another year. It's (quite literally) sickening what people do to themselves without considering the effects these substances can do when consumed in excess. Ughhh...
Farhan Rizal Anime adaptation
@@marcy1949 Boy am I so excited to watch it!
What's up Doc! I hope you've noticed easter eggs in this anime. Like when the red blood cells have no oxygen their red clothing is darker. There are other things, but I think it's best to let you find out on your own. lol
As an MA myself, you being a doctor and reviewing this anime is the greatest thing. Haha
I'm gonna try and find them all!
wait I never noticed that the red blood cells had darker clothes without oxygen >.> guess I need to rewatch it all and make sure I see everything kappa
@@biffnotsotannen1462 Yeah, watch for the little details. Like the fact that the platelets are kids. He did explain why they're kids last video. But if you actually know the details about platelets, you'll realize why you never see any teen/adult platelets ;-; again, the little details. Haha
Dr Hope's Sick Notes have fun and keep your eyes peeled. And keep tiny details in mind. Never know when that lost boot will come into play later.
It's technically not that their clothes turns darker (in the context of the show at least). Their jackets are reversible.
Can't wait til you get to the Cancer episode doc! My favorite of all and I think you'll love it as well.
Same that's episode 6 maybe
That one episode is cool and dramatic.
Everyone says they want the cancer episode reviewed... i cant wait for the parasite and the alllergy
Yea i'm so hyped for the allergy one xD it was the funniest to me
isaiascancino The allergy one nearly had me crying in laughter. Love it!
Definitely looking forward to the allergy episode review and breakdown but the parasite episode is a runner up for sure.
Achoo
I'm waiting for the final episode...
When Macrophage spinned, she resembled her real Cell Body
Reminds me of a certain female hand,mallet fighter in Mega Diemention Neptune.
Am I the one who imagined the Macrophage as a giant Pac-man eating everything prior to this episode?
like the one in "once upon a time... life"??
Nah, that's always how I had pictured the macrophage - at least until I watched this. XD
If you pay close attention to hemorrhagic shock part 1 and 2 you'll notice the macrophages cooking antigens
The absolute input you have on this and the context you provide with not only medical information but how you can relate all of this with your own career and life choices that led you down this path is absolutely astonishing. Well done god sir, you have made me an avid fan
LMFAO WHEN HE STARTED SINGING ALONG TO THE OPENING SONG😂😂😂🙏🏻🙏🏻🙏🏻👌🏻👌🏻👌🏻👌🏻
road ON Don't we all do that tho? 😆😆😆
On the one hand, as a teacher, am pleased as punch that that so many biology classes are jumping on this series as a teaching tool to make learning more fun and engaging.
On the other hand, as a MATH teacher, I'm a little perturbed that Biology is SUDDENLY everyone's favorite class now that they get to watch Anime for their freaking lecture.
When are they gonna make an Algebra Anime, dangit!?
Oh god no please 😭😭😭 algebra scares me
Ah yes, I want to see X cheating on Y and their relationship won't function, then when Y cheats on X, they still function.
You could easily make hour-long episodes. We would still watch them!
Hell yeah!
Patiently waiting for the Cancer cell episode.
Saaaame
Christopher K Nice Bro
Dont spoil it for him
SAME
The manga had a sequel to that episode. Maybe they'll make it?
i'm procrastinating on biology by...learning biology.....but these videos make me real happy so mehh
Cadet Grey you just made me remember I have a test in biology next week... xD
V1G4M1 mate you have it easy, its end of year exams for us down in new zealand... id better study or im not getting into uni
Cadet Grey oh daamn, yeah, you should study then xD I have around half a year until my final exams of college (I‘m always unsure if the german gymnasium is college in englisch but I think so?) xD that next week is just a „normal“ one xD
I feel you... I also have externals at the end of the year...
Basically the infected cells are saying "I've been infected, kill me." and that's just sad
Sometimes sacrifices are needed:(
Oh god, it reminds me of the screaming and howling of head crab zombies in halflife
"I dont eant to make this an hour long" pLEASE MAKE IT AN HOUR LONG, THIS IS BETTER THAN MY CLASS LMAO. Hopefully you'll make a new vid reacting to this, take care!
I'm so mad your channel didn't exist while I was still in school! I could of passed my science classes a LOT easier with you!
Katie Leffler too bad, this anime just debuted last Summer (in Japan) of this year.. 😥
Well, the anime too, of course. But I was referencing to Dr. Hope in general because all of his videos are neat
I love the timing so much. Literally when Cells At Work finished airing I just started college. I go to a science college so literally everything here is important to my education XD.
My favourite part is when the lecturer talked about how "Neutrophils would hunt down pathogens as if they have nothing else to do" then all the weebs in my class just started laughing like crazy...
Then she told us that white blood cells often die while fighting an infection and we were like:
Oh. ._.
But I already know platelets die in less than ten days so my broken heart can't be damaged any further T.T
Those poor children...
Me: *watches Hetalia* this is good *passes social studies*
Me: *watches cells at work* this is good *passes science*
Anime is a valid source
Hetalia gay. No homo, plz.
We need an animé about financial literacy and investing in stocks
Ham and Burr YES WE DO
Ham and Burr wolf and spice are about economy.
Need: Real pornstars react to hentai
I love that he is using game pieces from the Pandemic Board Game. Z-man games needs to get in touch with this guy!
I had to scroll a lot to find a reference to the Pandemic game!
The thing I like about this series is the fact that you don't stray from what your channel is about. You react and at the same time teach biology in simple terms. I have learned so much and remember it compared to taking a whole year of it in my sophomore year. I'm also glad you are enjoying it and not just milking this series.
Same! I like how the reactions, while part of the show, isn't the part that takes the most focus ♡
More like doctor explains cells at work lol
I am a Japanese listener. I was impressed watching your videos. You might already know, in fact the color of the red blood cell jacket is slightly different when it is in the artery or in the vein! According to the official setting, the jacket seems to be reversible.There is a fine ingenuity. Please watch it carefully. Sorry for my bad English (T_T)
Your english is great! Thanks for the information, it's great Japanese people watch these videos! >w
@@araragisenpai4088 I am so happy to be able to connect with people all over the world through Japanese animation. I expect the sequel of this video series.
I'm a senior high school student,but I want to communicate with foreign people more,so I'll study English.
Thanks for your comment !
Your English is amazing pal, keep it up 😁
@@eric_gz Thank you very much(^o^)
Hi ! Yes, she does!
Light red color when she is carrying oxygen
Dark red color when she is carrying CO2
You bobbing your head to the rythm of the opening was unexpectedly cute haha
The director for this episode, its also the director of Jojo's Bizarre Adventures, so all the similarities are completly on purpose
I found it cute when he sang along with the opening song! Hahaha.
Ikr TT💜🙈🙈🙈🙈
HE'S BEEN CONVERTED
I find the question of whether to treat the fever or not to be rather interesting. It's something I never thought about as one would typically see the fever as the problem instead of a side effect to your body trying to fix the actual problem.
Yeah, you don't often think about it that way. I kinda thought the fever was caused directly by the virus and not to fight it.
Knowing that's what the fever's there for, I'd probably actually prefer to keep the fever. If you're an adult - and not someone with a weak health in general - it shouldn't be that hard to deal with a fever. After all, you turn in sick from work when you get the flu, so you just have to lie on your couch and make sure to drink a lot of water/tea/juice/etc. to keep hydrated. If it helps slow down the virus a fever might actually mean that you'll get back on your feet faster?
It's also kinda like when you have a fracture or injury and one of the body's first response is inflammation which promotes healing to the injured site. And it also has the interesting question on whether inflammation should be reduced by using medication and ice packs. I think that in very severe cases where inflammation may damage surrounding muscle and nerves is when I think medication should be used. So I think it's quite and interesting question. ^.^
Well please do longer! I prefer hearing your teachings. More in depth. Really enjoyable. I love biology and your explaination feels sort of first love all over again! I would turn on yours and just listen whilst sketching on my desk ❤❤❤
1:18 I think the shoe falling off is just showing how the white blood cell's ability to transmigrate. They can slip through even the narrowest cracks. That's why the shoe got stuck. It's so quirky.
Me watching educational videos then got recommended with the episode 1 of this series,...
One hour later, I had watched three of them,...
conclusion : Dr. Hope is the best internet / RUclips doctor.
Good job doctor.
p.s: subscribed, commented, and shared.
My aunt 15 years ago "cartoons will never teach you anything" Me: ha
tec5x5 channel True... but it’s not a cartoon... it’s an anime lol
Anime is basically Japanese cartoon
@@BmacSoundsLab anime is 2d animation therefore it is also cartoons. It's just a sub genre that can stand on its own enough that people can forget that fact.
Even cartoons can teach you anything. Remember Dora the Explorer? it help me learn Spanish better back when I was 5 years old. LOL
More like cartoon is a sub genre of animation. Cartoons are typically associated with a very different distinct style that is more focused on the younger population. What you say is only true for Japan, outside Japan anime refers to a very specific style made by the Japanese.
Macrophages deadly force: *SIGNIFICANTLY POTENT*
I studied Biomedical Science in University, and I loveeeee anime A LOT. So I can't say how much I LOVEEEE this anime! Watching your videos makes it even better! The things you went through were exactly the things I had learnt in University, but of cos, it's just on the surface. But nonetheless, it's an enjoyable and knowledgeable series! Really hope you can share more information 'cos I really love learning new facts or even just refreshing my memory about our body systems, and you make Biology looks even more interesting too! I love how you look so passionate when explaining all the information to us! Kinda motivates me even more! (x
Keep up the good videos! (((:
Eyyy
-hifives-
I just realized that Macrophages wear a maid's uniform, colored white. Because they clean up dead things in the body, and carry a hatchet, a simple but effective weapon.
They carry different weapons, there was even one weilding a pink suitcase
That shot of her from above is actually some really smart cinematography. Shot in the Dark but her dress seems to be her cytoplasm while her head is her nucleus. In comparison to other cells, macrophages have far more cytoplasm in comparison to their nucleus than their white blood cell cousins.
The Macrophage carries a hatchet, while other immune cells carry knives, because macrophages are large ("macro") enough to kill multiple pathogens at a time, while others are only able to kill one at a time.
I would be completely okay with the video being longer than the actual episode.
GamerGodLink honestly same. I love how much insight the Doctor gives the series. It’s fascinating!
I don't mind an hour of lecturing if he's my teacher lol
Same.
I agree.
15:13 I didn't get all the medical refrences when i was watching the series... BUT AT LEAST I GOT THE JOJO REFRENCE!
Ur boy 15:13 i also got this jojo reference,
Wait I’m retarded why did I put 11:15 it was 15:13 I just edited it
This was made by David Productions, so I am very willing to believe that this is indeed a jojo reference.
JOJO Is so bad compared to other anime
LMAO
i just realised
there’s no ads on this
omg
Yea
I'm okay with an hour long video lol
Me too!
Yes yes yes
Well, dr hope's not okay, is he? You gotta be considerate for him, man.
Went here to comment the exact same thing. I'd still watch it all.
I wouldn't mind either...
2:39 omg that’s so funny! Literally last week (I’m a high school student btw) my biology teacher did a thing with us about viruses and about how their neither alive nor nonliving
Haha no way?! Must be a question they love asking
Schrödingers virus
"I didn't want to make this an hour long..."
I'll be down for that. Possibly have one episode within the 20 minute mark and other be an extended version of that with uncut educational content. Sign me up
watching with dad:
dad: anime is bad for you
me: its medical come and watch
dad: stared,speechless and leave
I made my mom watch Cells at Work! today, and for the first time in 20 years, she said that anime has finally done something beautiful and educational xD
That's make sense, because anime that aired on television is about a bunch of fighting guys, magical girls, or daily life drama. So boring.
@@verifeli and fanservice
verifeli they dont show masterpieces like violet evergarden
if the video is longer than 30 min i whould not have any problem at all... becoause i will learn more about it
I wish we had this anime and reactions from you 4 years ago during my virology and immunology classes 😢😢 I never understood transcription and translation....and just from this video and your explanations....I'm here screaming "I get it now!" 😅😅😅 thanks a lot doc! Another great video!
Love how he's using Pandemic game pieces in his cell model.
Yeah, especially that coronavirus has got one.
After you did the second episode I was already pretty much sure that you HAVE to do the entire anime, for a good reason! That's the most entertaining "react" series I have ever seen, simply because it's just not a guy watching at a screen overreacting to everything he sees without giving any other input, yours are educative and Fun to watch!
I'm so happy this wasn't a one time thing, definitely look forward to these every week.
1, 2, 3 4, we are cells at work!~ 😋
Edit: Omg I got a heart and a reply!
🎵 singing along 🎵
we are はたらく!
Even the doctor sings along 😂
WOOOOOOOOOO
HATARAKU
This is fantastic, especially for visual learners. I love how you break it down in between with drawings and rubber bands, bits and bobs. It really helps relate the mechanisms on the most basic level, instead of just reading words in a book.
Learning your body
From book = Normal mind
From education video = Wowing your mind
From Cells at work =Amazed your mind
Doctor react to Cells at work = Blow your mind
you could just watch 'em all at this point. the ongoing a-plot might interest you after all, even if you're too busy digging out medical facts instead of paying attention :p
MoonAir N I actually like watching his first reaction though.
@@kristineconstante9060 Of course. It is his most sincere, after all.
Don't matter at the end you ain't the ONE!
Can't count how many times I went "OHHH, so that's why x happens to my body!" And after hearing how my cells work, I now feel my cells are smarter than me. T.T
I've finished the anime season but it's fun to rewatch it with expert commentary. Thank you, Dr. H!
Those colored cubes look familiar... Someone been playing Pandemic? :)
Cells At Work is already an educative series but you help elaborate it further, and I may not pursue medicine but I’m so fascinated and grateful by your breakdowns for each episode. I enjoy it so much. Thank you so much for helping us learn more.
the official Hataraku Saibou developers made some extra material, which is free on their official website for educational purposes.
How to make a doctor an anime fan
Show this anime
2:23 He’s giving in!
More Cells at Work, more Dr. Hope, more learning! Yay~
17:40 I would love to hear a one hour lecture and an extended explanation in detail to be honest
Minor spoilers, but there's an episode further ahead that's all about the T cells! Super cool.
dont give spoilers i already watched the anime but with the dotors comments i enjoy it in another way, you could even say ...... its educational O_O
what? even story about our body has a spoiler?
there are no spoilers. just read some information or knowledge about our body..
I think I learned something!
*skips the educational parts*
No point reading it all when you already know it xD
@daviddare100 same
pfffft
hahahahaha I'm guilty of doing this a little!
I'm a proud person that can say that I listened to it all!
Small fact. Virgin T-Cell was renamed "Naive" T-Cell due obvious teen sex innuendo puns and references. :)
I like the use of the pandemic cubes
In an episode about a virus!
I came here to say this! I was like "are they what I think they are?"
What are those?
@@albertoandrade9807 those plastic beads I think. I would guess they are from that game...
Anime + education = MUST LEARN!
These videos are encouraging me to pursue a medical career. I love how fascinating and entertaining these videos trun out! Truly thank you!❤
No, don't XD
What the hell do you mean no don't? Don't stop someone from pursuing their dreams.
You need a doctor's degree and at least some work experience in order to have a final-tier position in the medical field. This particular field is notorious for being pricey, lengthy, and rigorous even before a doctorate's program. Thus, one should only major in it with genuine passion and interest, not merely on a whim. I believe Jonathan believed OP was thinking on a whim, which could prove to be a costly mistake in money and time. I took 3 years of medical in high school for EMT myself and decided to switch because memorizing 500 root words and other medical symbols/jargon as a "small warmup" of what's to come just wasn't worth it for me.
it's tough as you basically have to know everything. But it's fine if you love it. A piece of advice if you really want to pursue medical career, be strong and never give up. It can be stressful and busy and sometimes you'll be scolded (the doctors can be very strict to their students). You have lesser vacations too. But if you enjoy it, everything will be fine.
@@cardinal3353 Ah, yes. I'm sure some random person on the internet will stop him from pursuing his dream.
I guess that for a doctor, this is like watching "Marvel cameos" in every scene