SOS Response and DNA Repair

The SOS response is a global response to DNA damage in which the cell cycle is arrested and DNA repair and mutagenesis are induced. The system involves the RecA protein.The RecA protein, stimulated by single-stranded DNA, is involved in the inactivation of the LexA thereby inducing the response. It is an error-prone repair system that is attributed to mutagenesis.
SOS genes include lexA, recA, uvrA, uvrB, and uvrD.
Source : en.wikipedia.o...

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such complicated topic explained in so less time and so efficiently, thankyou !

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Your diagrams are on point and great to see and learn quickly from them !

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[@kaurviyadav6016]

Bhai sos response ki aisi video koi or na hai u tube pr...... Itna accha to pathfinder ki life science ki books mai bhi na diya.... Thanks bro keep it up👍✌

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[@hussainbiology]

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simple way to express how its work .thank you so much

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thanks for appreciation

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thank youu. I am 3 days away from my exam and I was going to give up on undestanding this mecanism and move on. until I found this video ! short and effective tusm

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Thank you so so much for helping me to understand and learn so much quicker! Great Explanation!!

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you are such a blessing, thank you very much sir!

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your explanations are amazing. Very appreciated, thank your for the video

[@hussainbiology]

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Daigramatic representation is superb that makes topic understand very quickly .. Osm

[@hussainbiology]

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Thank you so much for this wonderful piece of work!.....always very helpful🥰

[@hussainbiology]

thanks for appreciation.. glad it helps ✌️

[@shrutisingh8842]

terrific and amazing explanation 😊you saved my time 😊

[@hussainbiology]

Glad it helped!

[@carlhouck4387]

Much more concise than Shomu's Biology. I like that you get right into it as opposed to taking forever to introduce a new topic.

[@hussainbiology]

Thanks Carl for appreciation....
I know this world has no time so , i always introduce topic as quickly as possible so that we learn what we have to....
Almost all my videos are around 5-6 mins.
Thanks again

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Thanks a lot.... U make me feel the concepts simple and easy

[@hussainbiology]

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[@champanmei5259]

A clear n short presentation ....much thankful👍💚

[@hussainbiology]

Glad it was helpful!

[@ahmedshadulla7463]

It is uvr ABC Excinuclease.....operates the NER mechanism...

[@asraaal_dolaemy6138]

Thank you very much,only now i understand theSOS repair. 💓💓big love .

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[@affra.b946]

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wonderful diagrams and informative session .....THANK U A LOT

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thanks for appreciation

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Your explanation is just soo perfect and simplified....thank you 😊

[@hussainbiology]

You're welcome 😊

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Really great sir , explained complicate topic in such a ease way 😍😍

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@brtseif]

Lifesaver. Final tomorrow, this explains the process perfectly.

[@hussainbiology]

Thanks Ethan for appreciation..Glad to know that it helps....
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[@hussainbiology]

All the best....

[@muzzammilb3437]

Thank you! Your video helped a lot.

[@rulebreakersofmusic6784]

Sir ur classes makes my score and knowledge a lot tq sir😁

[@hussainbiology]

thanks buddy

[@snehaltonde3436]

What an amazing explanation sir
Keep uploading more videos !

[@hussainbiology]

thanks for appreciation... Glad to know that it helps

[@Diogenesthedog0]

Shukriya Bhrata shri

[@affra.b946]

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[@hoorbhatti1108]

Wonderful.

[@divyarao9368]

sir can u explain the new concept of primpol mechansism in dsb repair, it would be of great help

[@muzffarali3880]

Awesome work

[@hussainbiology]

thanks for appreciation

[@IBTSaiyadaIqraKamil]

Thank you so much.

[@hussainbiology]

You are most welcome... ✌️

[@babitasaroha2426]

can you please make a video on homologous recombination

[@fedouaoumamar3658]

thank you for helping but next time please slow down when you are speaking wish you the best

[@Fran0Ran0]

Fantastic teaching style. Thanks.

[@hussainbiology]

Thank you so much for appreciation........Glad to know that it helps....

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Thank you so much sir 🙏 🙏🙏🙏🙏

[@hussainbiology]

Most welcome

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Wonderful explanation and animation 👏👏👏
Thank you sir ✨

[@hussainbiology]

thanks for appreciation

[@nehitasingh4106]

hi sir can you please make a video on recombinational dna repair ??

[@pragyasharma3412]

Urr method of teaching is very unique...thanks a lot to clear my basic concept🙏🏻🌸🌸🙌🏻..can you plzz make a video on recombination and deletion mapping...plzz it will gonna soo helpful for me if uhh make this as soon as possible... please😇😇

[@hussainbiology]

Surely.... thanks

[@santhosh.c.rkutti2354]

Super sir

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Beautifully explained!!

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Thanks for appreciation.....and glad to know that it helps......
Keep supporting

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Saved at alot of time. Thanks

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Best explained

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Superb n excellent sir it is very clear now thank you so much. It helped me a lot

[@hussainbiology]

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Thanks

[@ifra2468]

This is amazing!!! 👏Thnks sir for such helpful videos..

[@hussainbiology]

thanks Ifra for appreciation.
Glad it helps

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Wonderful

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@blockchainguru1379]

Very nice explanation, but pls go little slow, and sound is not so clear.

[@hussainbiology]

thanks for appreciation..... and i will definitely be slow in future videos

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What a good video! Thank you!

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You are really awesome 🎓🎓🎓🎓

[@hussainbiology]

thanks for appreciation

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Thank you explaining in deep!

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[@swatisangwan4925]

Hussain Biology
Sir pls make a video lacture on expression of lac operon in merozygotes. all that constitutive and inducible phentotype.
Please, I will be so thankful to you.

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Thank u soooo much 🙏

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Thank you so much 🥰 sir... For good understand

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Awesome, ultimate explanation,

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super clear and helpful

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Woho thank you, I have my exame in 4 days, this was helpfull

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All the best

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Brilliant👍

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Thank you so much

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Good and easy explanation👏👏👏

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@@hussainbiology l used some of ur points in my lecture....thanks

[@shrutishetty8837]

Great video. It really helped me alot. I request you to upload a video on DNA repair photoreversal please.

[@hussainbiology]

Thanks Shruti for appreciation...
And the Photoreactivation video is here:
ruclips.net/video/CwuXOmtl_zI/видео.html

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Thank you so much for quick reply. Your videos are really helpful for me. Keep going❤

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thank you

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Thanku so much in short many knowledge 😍

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great video. easy to understand you!

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Thanks dear for appreciation..Glad to know that it helps..

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Thank you!

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Great work..........!

[@hussainbiology]

thanks buddy for appreciation...Keep sharing and supporting

[@arpankundu4982]

Lecture is very precious but pronunciation is not very clear...should not imitate foreign style ...otherwise very good

[@hussainbiology]

Thanks buddy....I will stick to real accent.

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I am fluent in English language, but I understand every work he says…maybe you are too dumb for this lol🤷🏻‍♀️

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Thank you sir

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Thank you sir ❤

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great! thank you

[@hussainbiology]

Most welcome

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@@hussainbiology i hope it will be video about the lab experimnet please.

[@affra.b946]

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[@virendrapatel550]

nice. I have a question. Can you tell me how the cell regulates the preparation of uvrC and uvrD proteins and uvrA protein as they all come under the same promoter?

[@hussainbiology]

I have not read any specific regulation for uvrC ,D, and A proteins but i can say the majority of gene expression is controlled via DNA methylation and for these genes to be regulated it must be the CpG islands present on the genes that on/off the expression of any gene by Methylation of CpG islands.

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Well explained!

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Thank you sir.

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You are welcome

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Well explained 👍

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thanks for appreciation..
Glad to know that it helps ✌️

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well explained

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Mashallah bhai bht acche

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Thank you, Sir.

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Thank you sir,
It really helped me

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wow!! awesome video thank u sooo much

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Glad to know that it helps.....

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thank you so much... it helps a lot

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🙏🙏🙏🙏🙏🙏🙏 dhanyawad sir ji

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[@Kmar26]

really helpful thanks

[@hussainbiology]

thanks for appreciation....Glad to know that it helps

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Ma Sha Allah

[@hussainbiology]

✌️

[@nehakumari-rj1qx]

Nice video sir...

[@hussainbiology]

Thanks Neha..... Glad to know that it helps.....

[@amishasingh6213]

nice explain

[@hussainbiology]

Thanks for appreciation...Glad to know that it helps..

[@affra.b946]

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[@rohanavinashphatak2747]

Live 100. Not much, but the most n absolute explanation than shomu

[@hussainbiology]

Thanks buddy for appreciation....

[@sinthy8447]

A bit slowly... Would be better! Thanks anyway!!!

[@alibehfarnia4782]

Deep Accent. When one has accent, at least, s/he tries to reduce her/his speed or put subtitle to let others understand what's going on.

[@affra.b946]

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[@debanjankar1109]

Can you please refer a book for this particular topic ?

[@saja4887]

Great Job :)

[@ramchandrasuthar2848]

Very nice analysis bhai ji

[@hussainbiology]

thanks bro

[@sravaninaraboina1216]

nuvvu

[@anushkasupakar3305]

So how does it make SOS repair a direct reversal repair mechanism? Since it is the last resort for the cell to repair extensive damages.

[@hussainbiology]

this happens to occur in bacteria as a global response mechanism.

[@anushkasupakar3305]

@@hussainbiology Okay so all the direct reversal mechanism occur only in prokaryotes right?

[@hussainbiology]

@@anushkasupakar3305 Na na....It occurs in Mammmals too.
Like Photolyases have vast diversity found within bacteria , fungi, plants and in animals too.
Furthermore direct reversals in mammals by MGMT protein
✓ AlKb mediated direct reversal in E.Coli.

[@anushkasupakar3305]

@@hussainbiology thank you for the clarification! Thanks a lot. Take care!

[@hussainbiology]

@@anushkasupakar3305 you are welcome...Keep sharing and supporting

[@haseenabegum7760]

Thanks sir

[@hussainbiology]

You are welcome...Keep sharing and supporting

[@kashfafiroz3758]

vry nice

[@hussainbiology]

Thanks Kashfa for appreciation...

[@nazishamin2548]

It will be nice to hear from you sir if you are from kashmir .

[@hussainbiology]

Yes Nazish , i am from Kashmir.. Greetings....😊

[@nazishamin2548]

Yes i am also from kashmir , the accent of your speaking made me recognise that you are a kashmiri too 😊.

[@nazishamin2548]

Nothing like that its my exam tomorrow and i am from srinagar brother.

[@hussainbiology]

@@nazishamin2548 All the best dear...

[@arivinmech4391]

What is sos genes

[@hussainbiology]

Any genes which help at the time of urgency

[@suriyaayob2895]

Nice

[@hussainbiology]

Thanks for appreciation....Keep supporting

[@priyasultania8943]

Best ❤️

[@poupouill21]

That's not an operon it is a regulon since it's not on the same gene

[@hussainbiology]

It is a type of Regulon , which falls under the group of operons........ i hope this makes sense

[@hussainbiology]

It is a type of Regulon , which falls under the group of operons........ i hope this makes sense

[@user-mn7yy3me1n]

Thank youu 😍.. now I understand.

[@hussainbiology]

thanks for appreciation...Glad to know that it helps

[@affra.b946]

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[@RehanKhanNISER]

thora shi se bolta ye nakli foreign accent boht ganda lgta hai...by the way video was nice and helpfull
i have exam in an hour.

[@hussainbiology]

Apologies........Will stick towards my real accent.

[@RehanKhanNISER]

@@mominayasmin6941 I don't even remember I commented this 😂😂

[@varshajetty1131]

Is it "Translesion " or "translation" DNA synthesis?

[@hussainbiology]

at 2:54 It is Translesion synthesis
The Translesion synthesis is a DNA damage tolerance process that allows the DNA replication machinery to replicate past DNA lesions such as thymine dimers or AP sites.It involves switching out regular DNA polymerases for specialized translesion polymerases (i.e. DNA polymerase IV or V, from the Y Polymerase family), often with larger active sites that can facilitate the insertion of bases opposite damaged nucleotides.

[@affra.b946]

ruclips.net/video/cXJLfSFm5oQ/видео.html

[@vijayalakshmi-wx7yg]

SOS full from enti sir

[@hussainbiology]

save our souls... an emergency signal used in Morse Code during emergency

[@vijayalakshmi-wx7yg]

@@hussainbiology thank you sir

[@hussainbiology]

@@vijayalakshmi-wx7yg you are welcome

[@renutailors4634]

Sir kya ye topic jo aap upload krte ho csir net ke liye h

[@hussainbiology]

G Poonam , all are for CSIR NET

[@jagan2058]

EXCELLENTTTTTT

[@hussainbiology]

Thanks for appreciation....keep supporting

[@affra.b946]

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