Doctor Klaper, WFPB & Vegan Speaker: Interesting DHA Update March 2023
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- Опубликовано: 29 сен 2024
- Dr. Klaper shares his thoughts on a subject he previously spoke about & now has an update!
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Dr. Michael Klaper is an experienced physician, an internationally-recognized teacher, and sought-after speaker on health and wellness. He resolutely believes that proper nutrition - through a whole food plant based diet - and a balanced vegan lifestyle are essential for health. He offers health tips on vegan nutrition.
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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Klaper nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, exercise or other lifestyle program.
Do whatever keeps you healthy and able to keep helping so many people. We need your knowledge and compassion in this world.
Thanks for the update. The DHA/Oi3 blood level relaxation to physiological values for non-consumers of exogenous DHA is not surprising.
It is however known that DHA/EPA in the blood has strong anticoagulation "blood thinning" effect.
In that KORA study most (~70%) of that (very old) population had hypertension, also overweight - thus clogged up arteries, CHD risk factors.
Low-dose ASS blood thinnger also strongly reduces dementia risk in such context, e.g. recent study PMC9145441. Even stronger:
"low-dose ASA for 10 years or longer (who likely use it because they have CHD or a related diagnosis putting them at an increased risk for cardiovascular events) demonstrated a strong protective effect on all dementia outcomes, especially for VD (HR [95% CI]: 0.48 [0.42 to 0.56])"
Anticoagulation can easily and alone explain effects here - as far as the effects are real in certain contexts. And ASS may be more safe - for those (non-vegans) who really need it.
It should be also noted that the effect in the KORA study comes mainly from an age-adjustment effect. Because of high age differences in the Oi3 groups. That makes things very dubious. (The age group ORs are much higher than the calculated outcome effect). And as mentioned in the study the effects are not well confirmed in many other studies / other contexts.
Best RCT data for cancer & LCn3 supplement: The huge VITAL RCT PMC6392053 found borderline significant 13% risk increase within only 5 years (!) for total invasive cancer (HR 1.13 ; CI 1.00-1.28). And a prior huge meta analysis of RCTs on (LC)n-3 & cancer, Zhang 2014 PMID 24568238, confirms that with similar statistical power: HR 1.10 near significant. Combined meta analysis yields clearly significant cancer risk at some 0.005 p-value - which is a massive brick, unlikely to dissolve with future data.
For younger people with more years to go this is very serious, as cancers (usually) form over decades. And LCn-3 also suppresses the immune function, which is important to block cancer development.
The "blood thinning" of hyperphysiological blood LCn-3 / supplement also increases hemorrhagic stroke risk and other bleeding risk.
Interestingly Dr. Fuhrman, which pushes & sells LCn-3 supplements, explains (correct) in other context that whole-food vegans are at higher risk for that bleeding because their artery vessels are not "protected" by fatty cholesterol layers.
So LCn-3 supplement may even further raise that hemorrhagic stroke risk in such vegans while at the same time they don't need the anticoagulation w/o clogged arteries, but rather need the opposite effect, effective coagulation.
Plant-based diets are associated with lower risk for cognitive impairment: E.g. recent PMC9392533, odds ratio = 0.45, 95% CI: 0.39, 0.52
So there is no problem in the first place?
Wonder if unsubstantiated hysteria may cause, not solve problems here?
So far I am as reluctant as before regarding LCn3 supplementation - particularly at younger age.
Wow, that was a lot. It's clear you have read up on this topic and are more knowledgeable than the average person here. Can you dumb down your response/recommendation for the average Joe as to the Pros/Cons of DHA supplementation?
Very interesting points and comment you made here! Regarding health interventions it is always worth to ask the question for whom and when it makes sense.
I disagree with "Whole-food vegans are at higher risk for that bleeding because their artery vessels are not "protected" by fatty cholesterol layers."
More accurate to say, vegans have more hemorrhagic strokes because of vitamin-b12 deficiency.
Source: Dr. Greger's nutritionfacts video on vegetarians-and-stroke-risk-factors-vitamin-b12-homocysteine
Your other arguments are sound. Thank you for posting.
Really interesting info, thank you - We need more research!
So what are his levels after 1 year of supplemental omega 3 from algal oil?
Can there be something in the diet that inhibits absorption? Is there a mineral or something else that binds with Omega 3s and by eliminating that rather than adding more you numbers might go up. Also, so interesting to hear a doctor reflect on their own health.
Could blue light toxicity affect DHA levels?
Make up your mind doc 😮
Would you take the same decision if you had the same test results being 40 years old?
Thank you Dr. Klaper for this. I appreciate your work and your honesty on this supject. I hope you test again in one year and report back.
Thank you so much for your updated thoughts on this confusing subject.
I trust your judgement on all things vegan,I am very grateful for your guidance.
Your thoughts about supplementing make sense,so I will follow your lead and start taking a DHA supplement also.
Thank you for everything you are doing for the Vegan community.
I would like to see you share an update of your levels after taking the supplement. I feel that it’s an important measure. Thank you.
Thank you, Dr. Klaper! Please make another update if future research makes you change your mind (again). 🙏
This is a man of integrity.
NOPE
The man isn't. Compare what he said 3 years ago to know.
@@daveforgot127He does explain why he has changed his mind, or is being pragmatic about it though. I think that is an indicator of an enquiring, scientific mind.
@@daveforgot127we all learn
@@daveforgot127 He literally admits he was wrong, that's what integrity is.
Best wishes, Doctor Klaper. Thank you for sharing this decision with us even though it was a personal one. Blessings to you.
Jeff Nelson just did a take-down of Dr. Klaper's video; I would like to see a response. ("Klaper's DHA Endorsement: What's the Evidence?" - VegSource on RUclips 4/12/2023)
ruclips.net/video/NEi4uYgkQpo/видео.html
Thanks SOOO much, Dr K! Will you consider reporting back to us with any subsequent test results after a period of 3-4 months (or longer) of supplementation? I truly value your integrity and honesty and the extensive research you have done on this. I deeply appreciate your passion for helping people to achieve optimal health so we can all be here for our family & friends and to live our lives' purpose!
God bless you dear Dr. Klapper… i started on DHA/EPA based on Dr. Fuhrman’s recommendation… we need your bright spirit around for a long long time! stay vibrant!
But those studies were not on vegans. So any fear based on that study seems irrelevant.
Maybe you should factor in your age as well.
It could be that our ability to synthesize DHA from ALA declines with age.
I encourage everyone who is mighty of the German language to read the book „Das erschöpfte Gehirn“ (= the tired brain) by Dr. Michael Nehls. Unfortunately, the book is not out in English yet. However, he explains his lifework which is Alzheimer research and explains a lot about algae omega 3 besides other important topics.
Thank you for sharing your insights, Dr. K! Better be safe than sorry! Stay healthy 🌱💚
So what did the book say about supplementation?
Thanks for the tip! Bought the audio book instantly with my remaining Audible credit.
Good to be part of those who are "mighty of the German language" :)
Any quick summary of the findings?
I'm in a parenting group for delayed speech. Many parents on there swear that their children started talking a lot more when they supplemented with DHA. I was curious if this was just timing, that their children started talking because they were ready, or if it was the supplement. Thanks for the video.
I absolutely believe it!
DHA definitely helps the brain.
can it help for stammers as well ?
My understanding is the omega 3 to omega 6 ratio is important. Having a higher ratio of omega 3 to omega 6 is helpful. One challenge for vegans is that many vegan foods contain a lot more omega 6, including sunflower seeds, tahini, soya beans and walnuts. Flax seeds are very beneficial for vegans because they have a high ratio of omega 3 to 6. This begs the question: if we reduce omega 6 intake and consume 2 tablespoons of ground flax seeds a day , is this sufficient or is omega 3 EPA/DHA supplementation still necessary?
Billion dollar question, and it doesn’t seem sustainable anyway. There’s omega-6 everywhere. I need pumpkin seeds for zinc. Well that’s bad news for omega-6. Sunflower seeds for vitamin E. Bad news again. Tahini for iron. You guessed it…
So now you're going to take a vegan supplement that gets it from seaweed you could have been eating? Why did you skip trying to get it from plants only to end up taking a supplement that gets it from plants? And how did you rationalize extrapolating from a study looking at non-vegans that are eating animals and therefore getting dietary DHA EPA, did that study get into their diet much? Perhaps I need to re-watch this and look into that study more I guess... But this would have been so much better if you would have taken the next step and tested yourself after eating nori and chlorella for a year. You skipped that very critical step. You did exactly what I was wanting to do except for that one step.
Please show us a study that says children need to supplement DHA EPA. The RDA is for infants, beyond that it is ALA. Rather than just say someone says children should supplement, this seems a bit like an appeal to authority without any science backing it up. As far as I know most vegans from conception don't supplement DHA EPA and don't have any evidence of problems with their sperm, retina or brain. It seems like if we want our children to adapt to eating plants properly then we would not push supplements on them that bypass the metabolic processes are body is engineered to do on its own.
This is a great Doctor and human being. It takes a wise soul to research facts and rectify opinions.
Saddens me to see someone, especially someone I admire so much, making decisions based upon fear. I have been Vegan for 38yrs and have NEVER taken and preformed EPA or DHA supplement. At 60yrs of age and nearly 4 decades without taking a DHA supplement, I would surely be showing signs of deficiency by now. I am not. This can and will be weaponized by non-vegans as "even Vegan doctors think a vegan diet is deficient in Omega 3" and potentially do more harm than good.
1. ALA is the ONLY Essential Omega 3 Fatty Acid (EFA) in humans and other herbivores, EPA/DHA are not essential as humans and all herbivores can make their own.
a. EPA is the EFA for fish and carnivores, they do not produce enzymes to convert ALA like herbivores do.
b. ALA converts at greater efficiency in those on a plant pure diet (study 5)
2. ALA converts to all 5 other forms including DHA in sufficient amounts (study 1)
3. ALA conversion happens:
a. mostly in tissues not the bloodstream
b. as needed in real time to maintain optimal ratios (study 6)
c. are internally regulated by the microbiome and epigenetics (study 5)
4. The conversion is Unidirectional, meaning DHA cannot retro-convert to any other form (study 2)
5. ALA/SDA/ETA have health benefits not provided by EPA/DHA. (study 3)
a. ALA alone has benefits above and beyond other sources of Omega 3 including downstream EPA/DHA from fish & algae (study 4)
6. Consuming preformed EPA/DHA can downregulate conversion of much more prevalent ALA in Vegans' diets, leading to potentially less efficiency and lower levels. (study 5)
Study1: Is docosahexaenoic acid synthesis from a-linolenic acid sufficient to supply the adult brain?
Abstract Link: pubmed.ncbi.nlm.nih.gov/25920364/
Full Study link: www.sciencedirect.com/science/article/pii/S0163782715000223?via%3Dihub
Study2: “Compound-specific isotope analysis reveals no retro-conversion of DHA to EPA but substantial conversion of EPA to DHA following supplementation: a randomized control trial”
Link: academic.oup.com/ajcn/article/110/4/823/5519526
Study3: “Determinants of fluid intelligence in healthy aging: Omega-3 polyunsaturated fatty acid status and frontoparietal cortex structure”
Link: Determinants of fluid intelligence in healthy aging: Omega-3 polyunsaturated fatty acid status and frontoparietal cortex structure - PubMed (nih.gov)
Study4: Plant-based omega-3s may boost heart health, reduce risk of heart disease
Researchers found that consuming ALA that is found in plant-based foods like walnuts and flaxseeds was associated with a 10% lower risk of cardiovascular disease and a 20 percent reduced risk of fatal coronary heart disease.
"When people with low levels of omega-3s in their diet ate ALA, they saw a benefit in terms of cardiovascular health," Fleming said. "But when people with high levels of omega-3s from other sources ate more ALA, they also saw a benefit. It could be that ALA works synergistically with other omega-3s."
Link: www.sciencedaily.com/releases/2022/03/220322150838.htm#:~:text=2-,Plant%2Dbased%20omega%2D3s%20may%20boost%20heart%20health%2C,reduce%20risk%20of%20heart%20disease&text=Summary%3A,of%20fatal%20coronary%20heart%20disease.
Study5: Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the precursor-product ratio of α-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort
“…the precursor-product ration from plant-derived ALA to circulating long chain n-3 PUFAs was significantly greater in non-fish eaters than in those who ate fish,” wrote the researchers.”
“…results suggested that the best conversion rates are by individuals that don't consume (preformed) DHA…”
LINK: ajcn.nutrition.org/content/92/5/1040.full
Study6: “The ratio of eicosapentaenoic acid (EPA) to docosahexaenoic acid (DHA) as a modulator for the cardio-metabolic effects of omega-3 supplements: a meta-regression of randomized clinical trials”
Link:www.sciencedirect.com/science/article/pii/S0965229921000030?via%3Dihub
ALA to DHA Conversion is more than sufficient for Humans:
Study: Is docosahexaenoic acid synthesis from a-linolenic acid sufficient to supply the adult brain? Link: www.sciencedirect.com/science/article/pii/S0163782715000223?via%3Dihub
Conversion rates increase in those eating only plants via epigenetic changes increasing production of conversion enzymes:
Study: Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the precursor-product ratio of α-linolenic acid to long-chain n-3 polyunsaturated fatty acids: results from the EPIC-Norfolk cohort Link: ajcn.nutrition.org/content/92/5/1040.full “…the precursor-product ration from plant-derived ALA to circulating long chain n-3 PUFAs was significantly greater in non-fish eaters than in those who ate fish,” wrote the researchers.” “…results suggested that the best conversion rates are by individuals that don't consume (preformed) DHA…” Unidirectional Conversion from ALA>SDA>ETA>EPA>DPA>DHA:
Study: “Compound-specific isotope analysis reveals no retro-conversion of DHA to EPA but substantial conversion of EPA to DHA following supplementation: a randomized control trial” Link: academic.oup.com/ajcn/article/110/4/823/5519526
ALA/SDA/ETA are not available from Fish/Algae oil, yet they are vital to improve brain function and brain matter preservation:
Study: “Determinants of fluid intelligence in healthy aging: Omega-3 polyunsaturated fatty acid status and frontoparietal cortex structure” Link: Determinants of fluid intelligence in healthy aging: Omega-3 polyunsaturated fatty acid status and frontoparietal cortex structure - PubMed (nih.gov)
2003 article title: Achieving optimal essential fatty acid status in vegetarians: current knowledge and practical implications.
"Clinical studies suggest that tissue levels of long-chain n-3 fatty acids are depressed in vegetarians, particularly in vegans. n-3 Fatty acids have numerous physiologic benefits, including potent cardioprotective effects. These effects have been demonstrated for ALA as well as EPA and DHA, although the response is generally less for ALA than for EPA and DHA. Conversion of ALA by the body to the more active longer-chain metabolites is inefficient" Do you really want to make your body work so hard for a lifetime to convert and absorb this stuff?
Is conversion really inefficient or just biologically selective based on nutrient requirements at the time. Junk dna turns out not to be junk after all!
@@Jeffs60 You clearly do not know anything about human health and physiology. Heme iron is cancer causing. Vitamin A is hepatotoxic and Choline increases TMAO. The precursors prevent cancer formation, and allow the body to use step-process pathways to endogenous regulate our systems to keep them in balance and homeostasis.
@@geoffpalmer6717 There is no evidence of your opinion unless you show a study that Heme Iron, Retinol or Choline does anything but prevent all disease for humans. Sure if someone consumes way too much of any that could be a problem but you must show a study why all centenarians in Okinawa and around the world always consumed a decent amount of Vitamin A1, B12, K2, Heme, Choline, DHA and C15:0 without any access to synthetic vitamins, supplements or fortified foods and yet it caused no disease but prolonged life with superb health.
@@Jeffs60 Vegans don't require as much inflammation reducing anti-inflammatory Omega's because our bodies are simply not as diseased and inflammatory as those eating animal flesh, high in pro-inflammatory Arachidonic Acid.
Observation is not physiology. More is not necessarily better. Please understand the difference.
Our society believes the only way to get Omega 3 is from fish. But newsflash: fish get their Omega 3 from algae. Nothing wrong with people doing the same thing. Algae oil for the win!
Great video! Thank you for sharing your findings.
You are so welcome!
Thank you for the update! I like and have been taking the brand name DEVA OMEGA-3 DHA-EPA 500mg from Algae for years now. I get my fatty acids tested once a year and am always in optimal range. I take one softgel every other day. I eat Whole Foods Plant-Based also, 5 years.
Thank you for this comment, I haven't had mine tested but also take 1 capsule every other day...I do this because I am a smaller person and to save money. I've been wondering if it's enough. I know I don't get it from other things because I avoid fatty foods that have it.
@@straightedgeveganbel2453 I weigh 140lbs. I forgot to mention I also eat one or two walnuts with it moments before breakfast.
@@nozroc7312 ok good to know!
Good to know this dose of supplementation works well! I am vegan and take a algae DHA of 250 mg daily. I think I will change my subscription to algae EPA+DHA.
Can you pls share with us the omega 3 supplement link to know from where did you buy it .
@DoctorKlaper Now that it's been about 6 months, can you recommend a brand? How are your results?
This man never ceases to amaze!! Dr. Klapper's video " foods that kill" put me on my plant based journey and it's been incredible! Appreciation to all!!
Dr. Klaper, thank you so much for your video! We are raising 3 kids on a vegan diet (oldest 6), and we sort of think the same, better not to supplement if we don't have to. I've been following your thoughts on DHA and really appreciate this update. Clearly, there is absolutely no lacking in your cognitive ability, especially given your ability to keep us updated on your own self experiment (even if it didn't quite go as you maybe expected.) Thank you for looking at research and self-experimenting and teaching us what you learn. My husband's levels were low when we checked for the first time 6 months ago. And we are very high in walnuts/chia/hemp/flaxseeds daily, healthy lifestyle, no alcohol or coffee or smoking, exercising and sleeping well, and whole food plant-based 95% of the time, so decided that he start supplementing then. We never stopped supplementing with the kids or myself (since I am breastfeeding and pregnancies), and I now feel even better about that decision having received this update from you, Dr. Clapper. All the best to you. And thank you for your work.
Hi Mila, have your husband's levels increased in the past 4-5 months? Just wondering if he has done anymore testing. Cheers 😊
@MilaDanceSport
@@indiahereiam2051 Hi! We haven't retested but have been suplementing ever since. I imagine they would have by now :)
@@MilaDanceSport if you ever do retest, could you please report back! Apparently you need over 2000mg a day for a small to moderate amount of DHA to reach your brain. I saw a study where they used spinal taps to test.
Thank you. (Edit: Jains are lacto vegetarian not vegan, although probably the largest percentage of vegetarian people in any religion are in Jainism, a survey reported on Wikipedia says 92%. Another 5% are vegetarian on certain days.) I have been following your videos on this subject, omega 3 supplements, and was looking forward to this video as you had said you would communicate your findings. My regards and good wishes.
The problem is that these tests are usually based on the average person, who probably eats meat or fish and maybe the SAD diet. So it's difficult to compare that with a long term vegan, who may require much less omega 3 than the average.
I recall going on a juice fast for a week and then having a blood test done. The GP said he was very concerned about my low white cell count, as it could be a sign of leukaemia. I got retested after a month of normal eating and my white cell count was normal! I also did a juice fast after I broke my elbow falling off a bike. I had an x-ray to see how it was doing 2 weeks after the fracture and the radiologist was shocked. He said he'd never seen such rapid bone healing in his life! So, we are so used to our 'normal' life that living either side of the bell curve just throws spanners in the works. I do hope that this experiment works and that we can all learn from it :)
I’ve closely watched you evolve on EPA and DHA supplements for vegans over the past few years. I am a vegan and an RD student studying nutrition in college myself. I did my main research paper for a nutrition class last semester on this exact topic. I personally supplement with algae oil to get preformed DHA/EPA and I also eat ground flax seeds/walnuts daily to get ALA through my diet.
I like how you talked about the Omega-3 index and explained the “ghosts” of red blood cells. I knew that index level was linked to brain health in research studies but I did not know how it was actually derived by breaking apart red blood cells so this video was educational for me even after studying the subject for a college class. Thanks for the update and information!
Do you recommend flaxseed oil for ALA?
@@morKraft Yes. Ground flax seeds are excellent for ALA. Only an adequate intake (AI) has been established for ALA and it is 1.6 grams for men or 1.1 grams for women. Two tablespoons of ground flaxseeds has exactly 1.6 grams of ALA. It has to be ground otherwise the whole seeds pass through largely undigested. I use a coffee grinder and make a small amount daily. Great on oatmeal.
Not sure about refined oil.
@@robertturner1308 I appreciate this info, thanks. What about flaxseed in oil form? How does it compare to ground flaxseed?
@@morKraft Flaxseed oil is very high in ALA. It has 7 grams per tablespoon. That is several times more than the AI of 1.6 grams per day of ALA for a man. If your goal is to get ALA flaxseed oil is excellent. It has more ALA than ground flaxseeds.
The issue is ALA from flaxseed oil still has to be converted in the body to EPA and DHA and for men they say that conversion rate is very low. So some people opt for algae oil as a way to ensure they are getting enough of the longer chain omega-3 fats since the algae have already done the conversion. That said, the only omega-3 fat with an AI set at all is ALA. There is not an AI for EPA or DHA at this time. Hard to press people to get a nutrient that has no agreed upon intake level even set.
It is just based on a few studies that people are pushing vegans to take EPA and DHA for brain health. I take EPA and DHA myself but totally understand others might prefer to rely on ALA rich foods. Dr. Klaper has gone back and forth on EPA and DHA supplements himself.
@@robertturner1308 Yes, I've been taking an algae oil supplement for a few years now as well. But I think maybe my dosage is too high (600mg DHA and 450mg EPA a day). Do you think it's too much? How much do you personally take?
Thank you for covering this currently hot topic. I was waiting for this sequel to your last post on this topic. God bless all your hard work and your ability to be so thorough in your efforts to reach your conclusion.
Thanks, fascinating. I might also get back to using DHA supplements. Would you please consider telling us about your levels in 12 months?
Thank you Dr Klaper, very informative video. We need your knowledge and wisdom on these issues.
I don't blame you and I hope it does all good things. Very curious about the 6 v 3 pathways and wondering if there hadn't been walnuts and hemp, just the flax and chia, if that wouldn't have allowed the 3s to flourish. I've been experimenting myself that way but haven't been tested yet, one tablespoon flax and seven of chia most days in my pitcher of very green smoothie in addition to my WFPBNSOS vegan high raw foods which for a while now have not included other nuts or seeds in order to see what happens. Appreciate your sharing
Most interesting. And for me a confirmation that I am doing the right thing and will continue taking an algae based Omega 3 supplement (250 mg DHA, 125 mg EPA) every day. Done that since being on a WFPB diet for the last three years. Thanx to Dr Klaper for being open minded and honest.
I am in the Philippines, 71 yrs old and on a pension. Any good brand that would not break my budget? I will have to order them via my daughter in Calif.
Thank you Dr Klaper. Very much appreciated
The DHA supplements are crazy expensive. All the pills from every brand taste/smell rotten. There are no regulations on supplements so you can't trust any brand. I'm sure if we tested most brands they will be shown to be fake or have far less DHA than claimed, and are probably loaded with impurities like saturated fats and mercury. This is totally frustrating. Do you recommend we try to get a prescriction for Lovaza?
I just hate the idea that anyone levels diet-war attacks on you over this. Especially in the plant-based and Lifestyle Medicine community. You're a good doctor making considered decisions and are always transparent as an influencer and open-minded. Don't anticipate blow-back and pay it no mind, I say. Godspeed
Thanks for not doing a Miley Cyrus 😅
Well reasoned, Doc. We can’t wait around for rcts with samples of 10,000 and decades of follow up.
Anticipating a future follow up vid on EPA/DHA levels, post supplementing? Thx Dr. K!
I agree with the lengthy comment of @xcast 1. My take is that when a research project is looking for casual connections like this, consideration has to be made for the diet and health of the participants. If the people suffering memory problems have low DHA, but also eat Western meat and dairy diet, they also will have the disease risk that go with it. And that includes dementia. The independent research, both laboratory, controlled testing and population studies, find that the closer a person's diet approaches WFPB, the less their risk of dementia. This debate is like the soy debate. Some say the phytoestrogen in soy protects against cancer, some say it can cause cancer. Populations who use soy and are plant based have virtual no breast cancer. But so do plant based populations that do not use soy. So soy neither causes or protects against breast cancer. Based on everything I've heard and read, l believe dementia is more of a compromised circulation induced hypoxia problem. IMHO.
Check the work of Axel Montague PhD, who is an authority on blood brain barrier and impacts of various lifestyle factors. He concludes that higher O3 helps the brain via maintaining the BBB and thereby lower chance of dementia. As does a good diet and exercise. As a WFPB eater for 10 years, with nuts and lots of olives, and DHA/EPA supplements (~ 200 mg/d algae based), my O3 index was 7.8% last year. I'm 68 yo. Will test again this summer. I too, am concerned about brain health as well as heart health.
Dr. Klaper: Could you please clarify whether you had been supplementing with EPA/DHA prior to your first test in 2020?
Thank you for sharing your experience.
Didn't he say that prior to 2020 he didn't concern himself with eating omega rich food? That's why he began eating omega rich food, tested again and hadn't improved. If he wasn't even concerned about eating omega food before 2020, it seems logical he wasn't taking supplements either. Right?
@@robinchristian5907 Here is my attempt at a transcription of his words at 13 minutes 18 seconds...
Dr. Klaper says "I was taking DHA & EPA for years. I stopped doing that, stopped emphasizing omega-3 rich walnuts and flax seeds etc. in my diet for a year, rechecked my omega-3 level and found that my 4.46% had now dropped down to 3.73. Hmmm, of interest."
I believe this quote means that he was supplementing directly with DHA/EPA and also eating walnuts and flax seeds prior to 2020. I was just hoping for confirmation that he was taking supplements in addition to eating the ALA omega-3 foods.
@@greensmoothieparty So he says he "was" supplementing! Thanks for typing that out, I didn't want to rewatch it. Do you still think you need confirmation...he states in clearly. But now I'm wondering why he thinks taking DHA & EPA "again" will solve his super low number. It was only "4.46% which is lower than Fuhrman's advice to be above 5, and 8 is optimal. But I guess it's better than 3.73 and his more recent lower readings. I guess that's all one can do.
We need an update on this. The DHA supplement prices have only been skyrocketing and no reasonable evidence that any brand is real.
I wonder if Doctor Ellsworth Wareham took dha supps, he was sharp as a tack until the end after 50+ years vegan...I will probably start too as I noticed some slight decline in sight after 5 years wfpb, which could also be from normal aging.
Dr. Wareham was a regular lifetime consumer of fish and his wife cooked with dairy. The cafeteria people at the hospital said he sometimes would have egg and cheese omelette.
@@Jeffs60 uh no, ive heard him talk about being vegan since age 50, you're calling him a liar and without proof you're just wasting your time buddy
@@spliter227 You believe everything anyone says? Wikipedia states he has fish and other sources too, one interviewer he said he was vegetarian, another interviewer he said he was vegan for 30 years, another interviewer he said he was vegan for 50 years and all he had to do was take only a B12 pill. Well you are the one who is already skeptical since you asked about DHA and what about Retinol, K2, Heme, Iodine and C15:0 where did he get that? And if you believe when he said he was vegan for 50 years and only needed to take a B12 pill please tell me what brand and type of B12 pill was he taking since the late 1950's? Do you also believe Milli Vanilli sang their own songs and Jim Bakker was a nice honest minister?
What I did notice is that th ALA stores are incredibly high, so your conversion rate of ALA to DHA EPA is inevitably going down. So you eventually need to supplement EPA DHA in your later years if you’re not going to eat fish unfortunately..
I wonder if dr. Klapper exercises? Many doctors say that exercise is the best remedy for cognitive decline. Weight- lifting especially. I really hope the supplements work!
what a superb analysis of risks and benefits and the science. You point out there is no perfect science. Even though over the years I've watched research related to Omega 3 index and am familiar with the tests, never did I understand their limitations. What an excellent, thorough and insightful discussion. You didn't comment on whether a fish based "clean" dha/EPA supplement could be acceptable. I'd be curious on that. Thanks.
Thank you Dr Klaper! We always learn so much valuable info from you and appreciate you so much. ❤
Thank you for your transparency and honesty Dr. Klaper. I am at a similar age to you and likely dealing with the same concerns.
very valuable info! Thank you for sharing. We are plant based eaters and as we get older we find we are absorbing fewer nutrients thru our plant based diets. It was recommended we take omega 3 supplements so I was very interested in your experience and I value your opinion.
Very good Dr. Klaper. Thanks for the honesty and transparency.
The problem with using walnuts and hemp for omega 3 is they're also high in omega 6 and the two omegas compete for the same enzyme. But age could be a factor as well I'm sure!
Thanks Doctor! I'm a big fan of yours and appreciate all your contributions to Vegans. I am curious to know if your numbers are better now that it is March 2024?
How does a regular person who is not a doctor know how much to take?
Thank you for this explanation, Dr Klaper.
Keep us posted on your levels, good luck appreciate your work.
Hmmmm, you have worked with Dr. Fuhrman who is a big proponent of supplementing with Omegas, maybe you were turned off by the fact that he sells it :)
I wonder how you keep your omega 6 to omega 3 ratio in balance with your vegetarian diet ? Also, 300 mg of DHA seems on the low end of what is potentially optimal. As a side note, cholesterol doesn’t cause heart disease, sugar / diabetes and inflammation cause it, as far as I know from recent studies.
19:45 In short, you probably should supplement with algae EPA/DHA. 👍🏻
You never fully address all your reservations regarding supplements. This is terrible and I think you know that. Not sure what made you change your mind?
I appreciate Dr. Klaper's sincerity and willingness to change his opinion based on research (as well as bloodwork)-- but this is not exactly based on new information. Dr. Fuhrman' has been a long-time ardent advocate of DHA supplementation based on years of solid research as well as his lifelong experience treating the vegan community. And he got ridiculed for this by several of the charismatic leaders in the vegan community. And , Yes, Dr. F sells his own DHA supplement but that's because he's passionate about their role in neurological health and he wants to provide the best to his patients. DHA/EPA supplements can easily go rancid if not properly manufactured or stored. It's Dr. Fuhrman who deserves thanks, (if not apologies from some!) or at the very least, recognition. Of course, Dr. Greger has advocated for supplementation of DHA for years as well.
@@markgarcia5845 The debate continues about whether the plant based or carnivore diet is healthier. The debate continues over climate change , over vaccinations, over a woman's right to choose over gun legislation, . And even over daylight saving's time. Debates will continue as long as people exist. I just hope the continue to exist into old age free of preventable neurological diseases. I'm going with Dr Fuhrman, Dr. Greger and neurologists, Team Sherzai, who keep up with current research. Oh yes, and PubMed.
Supplement with juggling. Ambidexterity is the best thing for your brain.
Thank you for your thoughts and thoroughness
Hope to hear updates with your omega 3 levels after the supplementation thank you
Are you going to post a follow-up video with your new Omega 3 Index number? Thanks
Why not just eat the foods you said humans were eating to get the correct health ? Is it just ethical for ? I’m looking for the diet best for health and I was told by all the plant based doctors it was vegan but now it self like there are dangers to our health without lots of supplements -dha zinc b12 choline selenium iodine b vitamins etc! Is it true if we eat animal foods we will get disease or not???
Ok, it’s been a year. Can you update your results after going on the supplements?
Clue: if you have significant earwax, you need more EPA/DHA
Do you have any links to information about this?
Thoughts on udos choice omega capsules ?thank you Dr klaper ❤
Great presentation Doctor. I will be curious to see where your DHA levels are one year from now.
"Those of you who have been following my work for a while". Well, yes indeed we have!! You rock!
I really look forward to your NEXT UPDATE of how your EPA/DHA is doing after taking supplements again. Thank you!!
You’re so cool, Dr. Klaper. Thank you for all you do. You are appreciated!!! 😊
I have leukemia, LGL and follicular lymphoma. WFPB. You just helped me decide to go on supplementation. I think the web diet is helping with q of life, btw.
I really admire that you used evidenced based science and are willing to change your mind. This is important and the mark of a good scientist and doctor.
Thank you so much for this update information! I will start to follow the suggestions. It's really valuable
Thank you Dr. Klaper for your data-driven analysis of DHA/EPA supplementation based on currently available literature and your personal test results.
It might be that at your age omega 3 index is lowering no matter what you do. We need another test from you after you have been supplementing to see that this is not the case.
Hecis the absolute angel of the plant based and whole food plant based community!!!
Thanks Dr Klaper. Very helpful!
Thanks so much for these updates!!! So helpful
please give us an update, we are out here listening!
Almost meet u in Santa RosaTHANK U💜
" Jes-Se- Out-&-Into- The- Real "
" Jes-Se- R- U- I- Z 👁"
" Jesse Ruiz "
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" Jes-Se- Out-&-Into- The- Real "
" Jes-Se- R- U- I- Z 👁"
" Jesse Ruiz "
I read that the conversion of ALA to DHA decreases with age.
How’s your book coming along Dr. K?
Thank you
I value your information and will do the same.😊
Wait, are you recommending vegan children supplement this instead of metabolically adapting to getting it from plants?
DID YOU TRY NORI AND CHLORELLA? It would have been a great test if you would have done this for at least a year and then tested.
Have you watched Dr. Peter Rogers' RUclips lecture on using supplements? He explores in depth the biochemistry of Omega 3. He himself is a Plant exclusive SOS free MD. Please watch and see if your conclusions still seem sound. He is definitely the last word on any plant-based discussion for me at this point; and I have watched and read books by all the leaders in this movement to educate myself so as to make informed health decisions.
I like Dr. Rogers but his weakness is that he has no clinical experience with patients eating a plant based diet. He is definitely an expert on brain scans and the evidence they provide regarding the dangers of the standard American diet. Cheers!
So what does he say?
@@greensmoothieparty I don't think clinical experience is as definitive as the biochemistry of the human body. Clinical experience is a one-off each time because the lifestyle of each individual is different so no solid conclusions only inferences can be drawn. The chemical activity in the human body though is the same to one degree or another each time two, or more elements interact. The end result may also differ as to degree. But if you follow the chemistry, then you know how your body is being affected by the choices you make. Something else about using flax seeds is that they have a powerful estrogenic effect and I am not aware that men need that. And the oils in the seeds can be rancid and therefore somewhat toxic as any oily foods can be. And there is no easy way to determine that for the average person.
@@lana7422 Please note that Dr. Rogers recommends that one would ideally choose a physician that has a few decades of clinical experience. I agree with him. Wouldn't it be great if all the well known plant based physicians (men & women) shared their omega-3 index along with their protocols for ALA and EPA/DHA. We might get to a better understanding more quickly. I am grateful that Dr. Klaper was willing to do so.
Peter Rogers is not a RD, chemist or Cardiologist. The answer is to have 2 cans of skinless and boneless sardines in olive oil per week and you will get all the proper absorbable complete protein, Vitamin A1, B12, D, K2, Omega 3, Selenium, CoQ10, Lysine, Iodine, Choline, Phosphorus, and Oleocanthal.
How did I grow my brain as baby? I got formula from day one which in the 1980s did not contain DHA/EPA. If I could grow my brain at an age of rapid brain growth, clearly my body can make enough of it. At least, I had enough DHA to become a PhD later in life.
All this contradictory information is driving my anxiety and depression up.
One minute I think that getting enough ALA from chia etc., the next there some contradictory info that makes me want to just drop all of this mess and introduce fish in my diet.
@@mayamorabito1669 If it drives you nuts, by all means, do it. (Maybe eggs would be a morally better/easier way to get DHA/EPA. There‘s also algae oil, but it’s expensive and spoils quickly.) I personally am not too worried, but I totally understand if other people are. Veganism is not a religion. It‘s about doing as little harm as possible. In case of DHA/EPA there seems to be no clear boundary. You have to take some care of yourself, too. Whatever you decide, it will be okay. All the best from Vienna!
Thank you for sharing!
Thank you Dr K.
According to (Nichols JAMA 2020) taking high high-dose fish oil supplementation increases the risk of atrial fibrillation. Even lower does 930mg EPA & 660mg DHA showed a trend towards increased incidence of atrial fibrillation. But does fish oil equate to omega 3 supplementation?
I supplement with Omega 3 daily as I have dry eye disease and when I take it my symptoms go away. Also keeps my joints pain free. I use Cod Liver Oil 1 tsp daily. I use Carlsen’s Lemon flavor which works well.