Way better than wasting hours on textbooks .. i was really confused as i just entered med school and didnt know how to study and wrap up .. but ur channel was a guide and ur teaching a guidance for me ☝️💯
MAO stands for monoamine oxidase, which is an enzyme that uses Tyramine as its substrate. In other words, MAO functions to regulate Tyramine level. High level of Tyramine possibly leads to the increased systolic pressure, even a hypertensive crisis because Tyramine acts as a catecholamine releasing agent. When a patient is taking MAO inhibitors, means that MAO is inhibited, so the patient should restrict Tyramine-containing food, such as cheese and beverage with alcohol or beer included, to prevent excessive Tyramine.
I’m a medical student from Guatemala on my fifth year on the University, actually rotating on Pediatrics, right now we’re learning about vitamin deficiencies in children and so far this has been the most helpful video of all (which are all amazing!), I know you took a lot of time making this one because B6 has so many functions, thank you so so so much, you’re helping the future doctors to be better. You’re an amazing teacher!
I don't know If you do this on purpose but how fast (and in flow) you explain subjects kind of forces my brain to understand faster. I retain more information than say, reading a textbook slowly. Thank you.
What I love about this video is that I learned HOW to remember what b6 does (not just facts from FA for rote memorization). Also, the enzyme is our buddy, proline hydroxylase!!!
As a Grad Student always refreshing myself on Nutritional Biochemistry I really appreciate how you link the processes together to give a BIG PICTURE. I think student struggle when they only learn bits and pieces and are not shown the LINKAGE between the nutrient and all the "Pre" and "Post" factors involved leaving them to try and put it all together. The linking of the normal physiology to the dysfunctional physiology and the correction is a skill all teachers should master!!! Bravo!
Really well made and ORIGINAL type of video; for a ADD'er like me its heaven. The connections to other systems and different biochemical pathways highlighted is very good and impressively laid out.. ty for your time to make this
cheese contains tyramine which is converted to noradrenaline in neuronal cell on the other hand MAO inhibitors are inhibiting metabolism of noradrenaline further increasing noradrenaline concentration in synapse and cause crisis that's called chesse reaction thats the reason cheese is contraindicated with MAO inhibitors. it was question asked in the video so I couldn't avoid 😁 Btw great videos ..keep it up 😍👍
it is niemann pick disease which is due to deficiency in sphingomyelinase leading to accumulation of sphingomyelin in tissues >>>>>. from egypt and a great support for u ..... you have helped me alot to understand vitamins , pulmonology and alot of things
Medicosis Perfectionalis well currently as it stands I don't have anywhere to stay haha (I actually live in a hostel... but it ain't permanent) your videos have been legitimately a massive help for me... one with educating some of the other people in here and also my own mental health while under quarantine. Just wanted to say thanks for the knowledge. Things should get better in the next few months hah... I hope.
My favourite B vitamin which I have as P5P. Critical for absorption and utilization of Zinc, and Magnesium. Critical for bulk of Amino acid metabolism. Critical for a range of neurotransmitters and hormones. Critical for absorption and utilization of B12. Critical for biosynthesus of Cysteine. Critical for hemoglobin synthesis. Truly the most important B vitamin. Note: pyridoxine hcl is toxic, p5p is the natural bioavbl form.
Disease that has deficiency of the enzyme sphingomyelinase is Niemann-Pick Disease which is a lysosomal storage disease -> accumulation of sphingomyelin -> Hepatosplenomegaly + Cherry red macula
Pyridoxine and pyridoxamine are predominantly found in plant foods; pyridoxal is most commonly derived from animal foods. Meats, whole grains, vegetables, and nuts are the best sources. Cooking, food processing, and storage can reduce vitamin B6 availability by 10 to 50 percent
If you look closely on that label for the one-a-day type vitamin you will see B6. Its very small however. 3MG in the middle of the label on the left side. I had to look carefully to see it.
I dont understand anything about chemistry, but I watched 3 of your vídeos in a roll😄you are só smart , and I love to see the comments Someone said he has ADD and I have ADHD .I think this is the reason I felt in love with yoir teachings ..I love health videos , and I'm taking supplements for my adrenal fatigue . L tyrosine.b6 and b5. You have a short explanation on tyrosine. Thank you ! I'm try to think what you looks like 😁 show your face one day😊
When B6 is high in the blood and no supplement has been taking with vitamine B6? There is a high homocystein. MMA is normal. B12 serum is 450. Sportive middle age man.Has atherosclerosis. What is the main reason why B6 is high then? Bad liverfunction? Is he not activating pyridoxine tot P-5-P? Why? Low vitamine B2? Low magnesium? Thank you in advance
Outstanding video! Everyone in my family show high levels of B6 in our ordinary blood tests. Yet, we all have demonstrated the side effects of being deficient in B6. I had a MI at 46, daughter is having seizures, neuropathy, nerve issues, etc. Can high B6 testing also mean one is deficient by genetic pathways?
Time to NOT recommend Pyridoxine. Recommend Pyridoxal-5-Phosphate (P5P) instead. According to the studies I seen, Pyridoxine HCL an issue when: 1) one takes >200mg/day - some set the limit @ >1000mg/day 2) over months if not years 3) I've read a peer reviewed paper1, which explained why Pyridoxal-5-Phosphate (P5P) doesn’t cause harmful side effects/B6-toxicity like Pyridoxine HCL does. I've also watched medical videos, some of which were talks at medical institutes or schools, which said the same. Interestingly, all commecially available preparations for neuropathy pain which include B6, ONLY do so in the Pyridoxal-5-Phosphate (P5P) form. None do so as Pyridoxine HCL. 4) The value of Pyridoxal-5-Phosphate (P5P) has been shown by dozens of studies, that those who already have neuropathy experience reduced neuropathic discomfort with therapeutic dosages of Pyridoxal-5-Phosphate (P5P). Vrolijk MF, Opperhuizen A, Jansen EHJM, Hageman GJ, Bast A, Haenen GRMM. (2017) The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. Toxicol In Vitro. 2017 Oct;44:206-212. doi: 10.1016/j.tiv.2017.07.009. Epub 2017 Jul 14. PMID: 28716455. „In conclusion, the present study strongly indicates that the neuropathy observed after taking a relatively high dose of vitamin B6 supplements is due to the vitamer that is used in the supplements, namely pyridoxine. The inactive form pyridoxine competitively inhibits the active pyridoxal-phosphate. As a consequence, the paradox arises that the symptoms of vitamin B6 supplementation are similar to those of vitamin B6 deficiency. Vitamin B6 supplements are used by a large number of people. The safety of vitamin B6 is debated and recently EFSA has lowered the upper limit for vitamin B6. The question is whether lowering the safe dose for vitamin B6 is the solution. Remarkably, even at relatively low dose, vitamin B6 supplementation has given rise to complaints. Our study indicates that the toxicity of vitamin B6 is not only determined by the dose, but by the vitamer in which it is taken. Perhaps it might be better to replace pyridoxine by pyridoxal or pyridoxal-phosphate as vitamin B6 supplements, which are much less toxic. In this way, the vitamin B6 paradox may potentially be prevented.“ Carlos-Alberto Calderon-Ospina, Mauricio Orlando Nava-Mesa & Ana María Paez-Hurtado (2021) Update on Safety Profiles of Vitamins B1, B6, and B12: A Narrative Review, Therapeutics and Clinical Risk Management, 16:, 1275-1288, DOI: 10.2147/TCRM.S274122 www.tandfonline.com/doi/full/10.2147/TCRM.S274122 An excerpt: “Relevant original articles on neurotoxicity of vitamin B6 in humans obtained by our searches included seven case reports/series, one prospective study, and one case-control study (Table 1).Citation39-,Citation47 In half of them, neurotoxic side-effects of vitamin B6 were mostly due to very high doses and/or long-term treatment and resolved after treatment cessation.Citation39-Citation41 Specifically, reported clinical neuropathy cases occurred in a timeframe of 2-24 months depending on the administered dose: after 12 months or longer with doses of ≤2,000 mg/day, and after less than 12 months with doses >2,000 mg/day.Citation39-Citation46 The first clinical assessment study of pyridoxine-induced neurotoxicity in humans by Schaumburg et alCitation47 included seven patients with severe sensory neuropathy in the extremities after taking 2,000-6,000 mg/day pyridoxine for 2-40 months. Four of these individuals were not able to walk. All symptoms, assessed through objective neurological diagnosis, improved after medication discontinuation.Citation47 Another case series report by Parry and BredesenCitation46 studied 16 patients with neuropathy (all assessed by history and examination, seven electrophysiologically confirmed diagnoses, two sural nerve biopsies) after taking 100-5,000 mg/day pyridoxine for up to 72 months. Patients with doses ≤500 mg/day showed neuropathy after 23 months on average, while those taking 5,000 mg/day developed symptoms on average after around 3 months. In contrast, none of the patients taking 50 mg/day for 6 months).”
Followed all of this , but not a mention of the recommended daily dose of Vit B6.. and you should have mentioned to make sure if you use a supplement to find the correct Pyridoxine HC1 and not Pyridoxine HYD which contains dangerous elements that can cause future problems..
I had b6 blood test and my result was just a bit higher than normal range, but i had eaten some food before test and I didn't know that fasting us required for b6 test, any how I just want to know is my body absorbing vitamin b6 properly
Thankyou very much sir I m a homemaker and my 4 years child has a delay speech problem can I give him vitamin B6 ?plz reply sir I have seen first time such an informative video
Hi, I myself have researched this over the years. What is said is that usually in doses starting from 20 mg up to 50 mg, in normal people can cause some level of nerve damage. BUT those people who have like epilepsy, this dose is very good, it helps alleviate seizures. So this to me a bit of a paradox! The recommended does is like 1 mg per day, but based on the research I have found we need more like 3 mg per day and up to 10 mg is good. SO I hope the Medicosis guy in the video will reply to what I have written here, get his Opinion.
If someone has a hard time breaking down foods, protein powder (measured organic acids- needs more aminos- supplementing with betaine hcl etc, balancing gut flora) is there an amino acid supplement you recommend? I supplement with co factors but struggling
@@MedicosisPerfectionalis Well ! You were not very helpful to the student or patient 😯 You SHOULD NOW THESE THINGS if you are a teacher of medicine.. Not impressed !
Thanks for missing me. I've been researching for 10 hours a day about COVID 19, what is it, where did it originate, how are reliable testing procedures being formulated, the numbers, avoiding the main News broadcasts, listening to virologists, Bill Gates, and conspiracy theories. Otherwise, I'm OK. We are experiencing shortages in some pharmaceuticals here in Canada. I'm also looking into herbal substitutes. And how are you? I don't know anyone who has been ill with any kind of flu. And you?
I started B6 supplement to cure my morning sickness, but didn't need to add an antihistamine. in fact antihistamines make me dysphoric which leads me to believe I'm an overmethylator, but I'm not even sure that's a thing. the B6 has been great for me, it's helping me make GABA and it's stabilized my mood and I sleep great (nearly impossible when you're pregnant). I'm trying to figure out why B6 helps the morning sickness and why I was so deficient in it. 🤔
btw B6 supplementation for morning sickness has been prescribed since the 1940s. wish someone would figure this one out, but you know... women's health meme.
You are very funny. I was prescribed vitamin B6 without explanation except I was deficient. Also deficient in Vitamin b12 and D3 - my gall bladder was removed in2014 and I’m on qysemia and now victoza as of 2 weeks ago which I’m injecting myself. These vitamins should be very important to supplement don’t you agree? And will you make any comments regarding MRNA and your thoughts to take such injection please. Thank you.
You listen to this video yourself and evaluate how the video is audible. If you are avaiable in front of a listener, he will surely slap your face such that no one can recognize you again.
You are speaking for people to understand or singing for people to enjoy your melody. Why are you in a hurry with high speed in speech? If too busy, first finish your work and then speak with low speed for audience to understand what you want to say. If your intention is only to exhibit your capability to audience, it is up to you.
Are you avoiding Koronaviruz topics because you know something is off about it and anything you say may cause your videos to be flagged and ruin your reputation? Yes or no?
No! If that had been the case, I would have deleted the previous Coronavirus videos. The only issue is that I have nothing new to say. Also, I am trying to help students with their exams, that’s the main purpose of this channel. Thank you so much for your comment!
6:12 i still don’t get the “dehydrogenase” even if I watched “B1” video too 😢 Please, if you have the time, simplify it for me Thank you anticipated! 🫶🏻
Way better than wasting hours on textbooks .. i was really confused as i just entered med school and didnt know how to study and wrap up .. but ur channel was a guide and ur teaching a guidance for me ☝️💯
You're very welcome!
I’m obsessed with the way you teach. No doubt after your videos medicine makes perfect sense.
Glad you like them!
MAO stands for monoamine oxidase, which is an enzyme that uses Tyramine as its substrate. In other words, MAO functions to regulate Tyramine level. High level of Tyramine possibly leads to the increased systolic pressure, even a hypertensive crisis because Tyramine acts as a catecholamine releasing agent.
When a patient is taking MAO inhibitors, means that MAO is inhibited, so the patient should restrict Tyramine-containing food, such as cheese and beverage with alcohol or beer included, to prevent excessive Tyramine.
Omg! Thanks GOD for internet, such good content for free! Thanks!
My pleasure 😇
Thank you so much for watching!
medicine makes so much sense when you understand what the flip youre talking about
Exactly 👍
You helped me understand in less than 30 minutes what I spent hours today trying to wrap my head around in my textbook. Thank you soo much!
You’re very welcome 😊
I’m a medical student from Guatemala on my fifth year on the University, actually rotating on Pediatrics, right now we’re learning about vitamin deficiencies in children and so far this has been the most helpful video of all (which are all amazing!), I know you took a lot of time making this one because B6 has so many functions, thank you so so so much, you’re helping the future doctors to be better. You’re an amazing teacher!
Thank you so much, friend!
Good luck 🍀 to you!
Me Iam here after two years 5 year medical student for pediatric rotation and I have presentation about vitamins
me after watching your videos:
- I feel like there’s a chance I could be a good doctor. 😂😂
Yes 👏👏
I am literally preparing for my upcoming exams from your channel, and I have a strong feeling that i am gonna get an “A” 🙌🏽🙌🏽 god bless you😤💪🏽
when you become a doctor, treat me if you can!
I don't know If you do this on purpose but how fast (and in flow) you explain subjects kind of forces my brain to understand faster. I retain more information than say, reading a textbook slowly. Thank you.
You’re very welcome 😉
What I love about this video is that I learned HOW to remember what b6 does (not just facts from FA for rote memorization). Also, the enzyme is our buddy, proline hydroxylase!!!
Wow 🤩
You’re amazing!
As a Grad Student always refreshing myself on Nutritional Biochemistry I really appreciate how you link the processes together to give a BIG PICTURE. I think student struggle when they only learn bits and pieces and are not shown the LINKAGE between the nutrient and all the "Pre" and "Post" factors involved leaving them to try and put it all together. The linking of the normal physiology to the dysfunctional physiology and the correction is a skill all teachers should master!!! Bravo!
Thank you so much, Sir!
I am honored!
You've earned another subscriber!
IT MADE PERFECT SENSE. YAY!!!
Thank you so much 😊
You earned another one
I appreciate you!
Took me about 5 days to understand this video…this lecture is very informative, like a medi rapper…
Thank you 😊
Really well made and ORIGINAL type of video; for a ADD'er like me its heaven. The connections to other systems and different biochemical pathways highlighted is very good and impressively laid out.. ty for your time to make this
Wow 🤩
Thank you so much 😊
cheese contains tyramine which is converted to noradrenaline in neuronal cell on the other hand MAO inhibitors are inhibiting metabolism of noradrenaline further increasing noradrenaline concentration in synapse and cause crisis that's called chesse reaction thats the reason cheese is contraindicated with MAO inhibitors.
it was question asked in the video so I couldn't avoid 😁
Btw great videos ..keep it up 😍👍
it is niemann pick disease which is due to deficiency in sphingomyelinase leading to accumulation of sphingomyelin in tissues >>>>>. from egypt and a great support for u ..... you have helped me alot to understand vitamins , pulmonology and alot of things
Yup!
Thank you so much 😊
I've started watching your videos just as a coping mechanism lmao I don't know why but they chill me out... lol it's great.
Thank you so much 😊
Coping with what?
Medicosis Perfectionalis well currently as it stands I don't have anywhere to stay haha (I actually live in a hostel... but it ain't permanent) your videos have been legitimately a massive help for me... one with educating some of the other people in here and also my own mental health while under quarantine. Just wanted to say thanks for the knowledge.
Things should get better in the next few months hah... I hope.
I hope 🤞
Take care, dear!
Thanks a million!
Medicosis Perfectionalis no problem :) hope to see more hah
Thanks 🙏
I wish I had you instead of Boars and Beyond. They're great - you're greater.
Thank you so much, my friend!
Awesome sir. You have no idea how much you have made this easy for me....🙌🏼🙌🏼🙌🏼👍🏽👍🏽👍🏽👍🏽
Thank you so much 😊
My favourite B vitamin which I have as P5P. Critical for absorption and utilization of Zinc, and Magnesium. Critical for bulk of Amino acid metabolism. Critical for a range of neurotransmitters and hormones. Critical for absorption and utilization of B12. Critical for biosynthesus of Cysteine. Critical for hemoglobin synthesis.
Truly the most important B vitamin.
Note: pyridoxine hcl is toxic, p5p is the natural bioavbl form.
Wow, this was great. Thank you so much for correlating everything!
You’re very welcome 😊
I wish I had a teacher like you growing up
Thank you ☺️
Disease that has deficiency of the enzyme sphingomyelinase is Niemann-Pick Disease which is a lysosomal storage disease -> accumulation of sphingomyelin -> Hepatosplenomegaly + Cherry red macula
two hours of detailed medical information, as told in 23 minutes.....
:)
Pyridoxine and pyridoxamine are predominantly found in plant foods; pyridoxal is most commonly derived from animal foods. Meats, whole grains, vegetables, and nuts are the best sources. Cooking, food processing, and storage can reduce vitamin B6 availability by 10 to 50 percent
For your question, did you wanna mention Niemann-Pick disease? 🤔
If you look closely on that label for the one-a-day type vitamin you will see B6. Its very small however. 3MG in the middle of the label on the left side. I had to look carefully to see it.
Thanks to GOD that we have you
Thank you so much 😊
I dont understand anything about chemistry, but I watched 3 of your vídeos in a roll😄you are só smart , and I love to see the comments Someone said he has ADD and I have ADHD .I think this is the reason I felt in love with yoir teachings ..I love health videos , and I'm taking supplements for my adrenal fatigue . L tyrosine.b6 and b5. You have a short explanation on tyrosine. Thank you !
I'm try to think what you looks like 😁 show your face one day😊
Thank you so much 😊
I appeared on 2 or 3 videos!
I swear his voice and way of lecturing stick to my mind even in my dreams when I sleep! HAHAHAHAHAHAHAHAHAHAHAHAH!
Thank you so much!
I don't know why other medical channels are more famous than you
Just wait a few years :)
When B6 is high in the blood and no supplement has been taking with vitamine B6? There is a high homocystein. MMA is normal. B12 serum is 450. Sportive middle age man.Has atherosclerosis. What is the main reason why B6 is high then? Bad liverfunction? Is he not activating pyridoxine tot P-5-P? Why? Low vitamine B2? Low magnesium? Thank you in advance
What a fantastic presentation.
Thank you 🙏
Difficency of sphingomyelinase enzyme cause Neiman pick disease
Outstanding video! Everyone in my family show high levels of B6 in our ordinary blood tests. Yet, we all have demonstrated the side effects of being deficient in B6. I had a MI at 46, daughter is having seizures, neuropathy, nerve issues, etc. Can high B6 testing also mean one is deficient by genetic pathways?
Try an organic acids test
The best video I've seen on the topic, amazing!
Thank you so much 😊
I'm speechless. But thank you.
Thank you so much 😊
Where have you been for the past few weeks?
Is everything ok?
this is a great vid
Thank you 🙏
Cures PMDD and PMS apparently. In high doses.
the chemistry slander
Love your teaching style. Can subclinical B6 deficiency be caused by malabsorption issues - crohn’s, coeliac etc ? 😊
May be!
I don’t know 🤷♂️
Yep
Time to NOT recommend Pyridoxine. Recommend Pyridoxal-5-Phosphate (P5P) instead.
According to the studies I seen, Pyridoxine HCL an issue when:
1) one takes >200mg/day - some set the limit @ >1000mg/day
2) over months if not years
3) I've read a peer reviewed paper1, which explained why Pyridoxal-5-Phosphate (P5P) doesn’t cause harmful side effects/B6-toxicity like Pyridoxine HCL does. I've also watched medical videos, some of which were talks at medical institutes or schools, which said the same. Interestingly, all commecially available preparations for neuropathy pain which include B6, ONLY do so in the Pyridoxal-5-Phosphate (P5P) form. None do so as Pyridoxine HCL.
4) The value of Pyridoxal-5-Phosphate (P5P) has been shown by dozens of studies, that those who already have neuropathy experience reduced neuropathic discomfort with therapeutic dosages of Pyridoxal-5-Phosphate (P5P).
Vrolijk MF, Opperhuizen A, Jansen EHJM, Hageman GJ, Bast A, Haenen GRMM. (2017) The vitamin B6 paradox: Supplementation with high concentrations of pyridoxine leads to decreased vitamin B6 function. Toxicol In Vitro. 2017 Oct;44:206-212. doi: 10.1016/j.tiv.2017.07.009. Epub 2017 Jul 14. PMID: 28716455.
„In conclusion, the present study strongly indicates that the neuropathy observed after taking a relatively high dose of vitamin B6 supplements is due to the vitamer that is used in the supplements, namely pyridoxine. The inactive form pyridoxine competitively inhibits the active pyridoxal-phosphate. As a consequence, the paradox arises that the symptoms of vitamin B6 supplementation are similar to those of vitamin B6 deficiency. Vitamin B6 supplements are used by a large number of people. The safety of vitamin B6 is debated and recently EFSA has lowered the upper limit for vitamin B6. The question is whether lowering the safe dose for vitamin B6 is the solution. Remarkably, even at relatively low dose, vitamin B6 supplementation has given rise to complaints. Our study indicates that the toxicity of vitamin B6 is not only determined by the dose, but by the vitamer in which it is taken. Perhaps it might be better to replace pyridoxine by pyridoxal or pyridoxal-phosphate as vitamin B6 supplements, which are much less toxic. In this way, the vitamin B6 paradox may potentially be prevented.“
Carlos-Alberto Calderon-Ospina, Mauricio Orlando Nava-Mesa & Ana María Paez-Hurtado (2021) Update on Safety Profiles of Vitamins B1, B6, and B12: A Narrative Review, Therapeutics and Clinical Risk Management, 16:, 1275-1288, DOI: 10.2147/TCRM.S274122 www.tandfonline.com/doi/full/10.2147/TCRM.S274122
An excerpt:
“Relevant original articles on neurotoxicity of vitamin B6 in humans obtained by our searches included seven case reports/series, one prospective study, and one case-control study (Table 1).Citation39-,Citation47 In half of them, neurotoxic side-effects of vitamin B6 were mostly due to very high doses and/or long-term treatment and resolved after treatment cessation.Citation39-Citation41 Specifically, reported clinical neuropathy cases occurred in a timeframe of 2-24 months depending on the administered dose: after 12 months or longer with doses of ≤2,000 mg/day, and after less than 12 months with doses >2,000 mg/day.Citation39-Citation46 The first clinical assessment study of pyridoxine-induced neurotoxicity in humans by Schaumburg et alCitation47 included seven patients with severe sensory neuropathy in the extremities after taking 2,000-6,000 mg/day pyridoxine for 2-40 months. Four of these individuals were not able to walk. All symptoms, assessed through objective neurological diagnosis, improved after medication discontinuation.Citation47 Another case series report by Parry and BredesenCitation46 studied 16 patients with neuropathy (all assessed by history and examination, seven electrophysiologically confirmed diagnoses, two sural nerve biopsies) after taking 100-5,000 mg/day pyridoxine for up to 72 months. Patients with doses ≤500 mg/day showed neuropathy after 23 months on average, while those taking 5,000 mg/day developed symptoms on average after around 3 months. In contrast, none of the patients taking 50 mg/day for 6 months).”
So Profound Dr ! Amazingly.
Followed all of this , but not a mention of the recommended daily dose of Vit B6.. and you should have mentioned to make sure if you use a supplement to find the correct Pyridoxine HC1 and not Pyridoxine HYD which contains dangerous elements that can cause future problems..
Do you make videos about Pyridoxine HCl and the difference between that and the natural form?
I really like your videos... Please make a video on vitamin E as well...
Ok 👍
@@MedicosisPerfectionalis thank you... u r a great teacher.. u have got the excellent teaching skills✨
This is amazing
Thank you so much!
Dude! I freaking love you!
Love your frikken videos
Thanks 😊
I had b6 blood test and my result was just a bit higher than normal range, but i had eaten some food before test and I didn't know that fasting us required for b6 test, any how I just want to know is my body absorbing vitamin b6 properly
Is pyridoxal 5 phosphate the best type of b6 to supplement with ?
MAOI + Fermented foods = HBP?
Can you advise me how can I remember the whole enzymes and other components in this video???
Read a lot, and practice active recall.
Rinse and repeat!
So helpful💫👌
Thank you so much 😊
as usual great video and content ! which source or book do you use to get your data ? love u from Egypt
I use a lot of textbooks for biochemistry, like Lippincott’s, MN Chatterjea textbook of Biochemistry, Goljan biochemistry and others.
@@MedicosisPerfectionalis great.. I appreciate your work♥️
Thanks 🙏
Would excess ALT and AST means more gluconeogenesis happens in the liver ? Thx for the video
It means that there’s is a lot of transamination happening.
@@MedicosisPerfectionalis and is a lot of transamination bad? Do you maybe have a video on this?
16:25 Answer: DBH
I know because I have an issue on this enzyme..
My Dr. did give me to Take Vit B 6 because a have vertigo but After a Take even a half of it , i geht so slepy , idkw ...
Thankyou very much sir I m a homemaker and my 4 years child has a delay speech problem can I give him vitamin B6 ?plz reply sir I have seen first time such an informative video
I am not a doctor. I just teach!
Please don’t take any advice from anyone who hasn’t personally seen and examined your child.
Would you say that 25mg of pyridoxine hcl or 25mg of P5P is too much to cause nerve damage?
Hi, I myself have researched this over the years. What is said is that usually in doses starting from 20 mg up to 50 mg, in normal people can cause some level of nerve damage. BUT those people who have like epilepsy, this dose is very good, it helps alleviate seizures. So this to me a bit of a paradox! The recommended does is like 1 mg per day, but based on the research I have found we need more like 3 mg per day and up to 10 mg is good. SO I hope the Medicosis guy in the video will reply to what I have written here, get his Opinion.
SUPERB!!!
Thank you 🙏
When you get a change could you do one of these on hydroxychloroquine
Ok 👍
Also, I have talked about it before in my lectures on "Rheumatoid Arthritis Management"
@@MedicosisPerfectionalis will check it out
Thank you so much 😊
It’s in my “Rheumatology” playlist.
any connection to Duprin's contracture?
if u give monoamine oxidase inhibitors with tyramine that will cause hypertensive crisis .
Yup
Thank you and it is great!
My pleasure 😇
Niemman pick?
Sphingomyelinase deficiency is seen Neiman pick
"Pyridoxine bby!"
I- lol XD
Thank you Sir
Whoa my brain! Maybe if I watch 10 more time I’ll learn something 🤔
You’re good!
can u recommend vitamins for acne, scars, folliculitus ? and hairfall and white hair at one side of the head ? ;/
Why do you think that these problems are caused by vitamin deficiency? That’s an open question rather than a foregone conclusion.
Medicosis Perfectionalis because i have seen people taken various vitamins for severe acne and it works for them eg pantothenic acid.
If someone has a hard time breaking down foods, protein powder (measured organic acids- needs more aminos- supplementing with betaine hcl etc, balancing gut flora) is there an amino acid supplement you recommend? I supplement with co factors but struggling
I don’t know 🤷♂️
@@MedicosisPerfectionalis Well ! You were not very helpful to the student or patient 😯 You SHOULD NOW THESE THINGS if you are a teacher of medicine.. Not impressed !
NOW = KNOW Correction.. " You should KNOW " OR explain to the poor guy why you don't know...
Your voice is kinda funny😂
btw video is great 👌 really helpful❣️
Thanks for missing me. I've been researching for 10 hours a day about COVID 19, what is it, where did it originate, how are reliable testing procedures being formulated, the numbers, avoiding the main News broadcasts, listening to virologists, Bill Gates, and conspiracy theories. Otherwise, I'm OK. We are experiencing shortages in some pharmaceuticals here in Canada. I'm also looking into herbal substitutes. And how are you? I don't know anyone who has been ill with any kind of flu. And you?
Take care, dear!
Stay safe and happy!
@@MedicosisPerfectionalis THANK YOU AND YOU AS WELL.
Thanks 😊
gates is a puppet of the chinese and they use him to spread propaganda onto the unsuspecting , low iq public
Because cheese and wine have a lot of histamine?
I started B6 supplement to cure my morning sickness, but didn't need to add an antihistamine. in fact antihistamines make me dysphoric which leads me to believe I'm an overmethylator, but I'm not even sure that's a thing.
the B6 has been great for me, it's helping me make GABA and it's stabilized my mood and I sleep great (nearly impossible when you're pregnant).
I'm trying to figure out why B6 helps the morning sickness and why I was so deficient in it. 🤔
Take care of Vitamin B6 supplements, higher dose than recommended daily value can cause toxicity and many neurological problems.
B6 boosts creativity, i believe a good dream is a good sleep
Because oxidation cause lost b6 and zinc from urine
btw B6 supplementation for morning sickness has been prescribed since the 1940s. wish someone would figure this one out, but you know... women's health meme.
@@mroxannevh Hi. Really like your answer. Please can you tell the resources that you have found about B6 from 1940's.Thanks
How can I get pdf of lecture ¿😍
Available on my website: www.medicosisperfectionalis.com/
Is it good for deppression and anxiety?
I don’t know 🤷♂️
very very helpful:-)
I like the explanation because it is quick, informative, and fun.
If the patient is consuming MAOI along with tyramine containing food it may leads to hypertensive crisis yeahhhhhh... 🎉
he's such a sassy teacher
Hehe 🙃
Is it just me but the voice is so similiar wit Otis Milburn Voice's lol
Has a cure to Corona virus been discovered?
Not yet
15:45 someone pls make this an actual song
You are very funny. I was prescribed vitamin B6 without explanation except I was deficient. Also deficient in Vitamin b12 and D3 - my gall bladder was removed in2014 and I’m on qysemia and now victoza as of 2 weeks ago which I’m injecting myself. These vitamins should be very important to supplement don’t you agree? And will you make any comments regarding MRNA and your thoughts to take such injection please. Thank you.
You listen to this video yourself and evaluate how the video is audible. If you are avaiable in front of a listener, he will surely slap your face such that no one can recognize you again.
بدي اصير زيك
:)
Subscribing thanks so much
My pleasure 😇
a regular motor-mouth
Nieman pick disease
Pyridoxine
???
Isn't that found in the Sphincter 😂😂
Hi
Hello
You are speaking for people to understand or singing for people to enjoy your melody.
Why are you in a hurry with high speed in speech? If too busy, first finish your work and then speak with low speed for audience to understand what you want to say. If your intention is only to exhibit your capability to audience, it is up to you.
Here here.. I quire agree.. most unprofessional..
Are you avoiding Koronaviruz topics because you know something is off about it and anything you say may cause your videos to be flagged and ruin your reputation?
Yes or no?
No!
If that had been the case, I would have deleted the previous Coronavirus videos.
The only issue is that I have nothing new to say.
Also, I am trying to help students with their exams, that’s the main purpose of this channel.
Thank you so much for your comment!
Medicosis Perfectionalis That makes sense! Keep up the good work! My gf loves your videos!
LOL this is such a weird question
EXCUSE ME excuse me! 🤪
@@Uncensoredtruth777 Who's this idiot ? Nothing to do with the video..
you talk a little too fast.
Far too fast for students to take in.. Not good.
Too much information to take it would be simplier having shorter video to learn easily . I got adhd and nooppe i aint watching this
So did I and he left out some important information regarding which form of Pyridoxine supplement should be taken and the daily dosage..
6:12 i still don’t get the “dehydrogenase” even if I watched “B1” video too 😢
Please, if you have the time, simplify it for me
Thank you anticipated! 🫶🏻