High CRP Causes (When Should You Start Antibiotics?)

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  • Опубликовано: 10 июл 2024
  • What level of CRP warrants treatment with antibiotics? Is elevated CRP (C-Reactive Protein) a reliable marker of bacterial infection? How high is CRP in bacterial infections (pneumonia, sepsis) versus viral infections (acute bronchitis, influenza, common cold)? What threshold is most reliable in differentiating between viral and bacterial infections? How can we use CRP to monitor the response to treatment? In this video, you'll learn how to get the most out of this widespread test and avoid the most common mistakes. If you use CRP in clinical practice, I also recommend you read the articles I included in the references.
    If you want to make sure that you don't miss a life-threatening diagnosis like sepsis or a CNS infection, this free online course is for you:
    A Clinical Approach to Serious Infections in Adults: What Every Physician Should Know:
    drviktorkotarski.podia.com/re...
    DISCLAIMER: Please, always keep in mind that my videos are intended for educational purposes only. The content of my videos is NOT medical advice. I do not practice medicine over the internet. If you are a patient and have any questions about your health, please talk to your doctor.
    CHAPTERS:
    00:00 Introduction
    00:55 Normal CRP levels , CRP levels in viral respiratory infections, CRP levels in pneumonia
    03:08 Different units of mesurement for CRP
    03:35 How fast does CRP increase?
    04:30 How CRP levels change over time in uncomplicated viral infections
    06:15 Non-bacterial and non-infectious causes of elevated CRP
    07:12 The use of CRP in monitoring the response to treatment
    REFERENCES & RECOMMENDED READING:
    1. Steurer J, Held U, Spaar A, Bausch B, Zoller M, Hunziker R, et al. A decision aid to rule out pneumonia and reduce unnecessary prescriptions of antibiotics in primary care patients with cough and fever. BMC Med. 2011 May 13;9:56.
    2. Ruiz-González A, Utrillo L, Bielsa S, Falguera M, Porcel JM. The Diagnostic Value of Serum C-Reactive Protein for Identifying Pneumonia in Hospitalized Patients with Acute Respiratory Symptoms. J Biomark. 2016;2016:2198745.
    3. Andreeva E, Melbye H. Usefulness of C-reactive protein testing in acute cough/respiratory tract infection: an open cluster-randomized clinical trial with C-reactive protein testing in the intervention group. BMC Fam Pract. 2014 May 2;15:80.
    4. Llor C, Plana-Ripoll O, Moragas A, Bayona C, Morros R, Pera H, et al. Is C-reactive protein testing useful to predict outcome in patients with acute bronchitis? Fam Pract. 2014 Oct;31(5):530-7.
    5. Melbye H, Hvidsten D, Holm A, Nordbø SA, Brox J. The course of C-reactive protein response in untreated upper respiratory tract infection. Br J Gen Pract. 2004 Sep;54(506):653-8.
    6. Fan SL, Miller NS, Lee J, Remick DG. Diagnosing Sepsis - The Role of Laboratory Medicine. Clin Chim Acta. 2016 Sep 1;460:203-10.

Комментарии • 75

  • @clinicaltips8926
    @clinicaltips8926  Год назад +7

    I want to remind everyone that my videos are for educational purposes only. Of course, everyone is welcome to watch, but the information I present is most useful for junior doctors, nurses, and students. As I stated in the description of every video and on my channel homepage, none of this is medical advice for patients. I don't practice medicine over the internet. If you are a patient and have any questions about your health, please get in touch with your doctor.

  • @adamtajti8419
    @adamtajti8419 6 месяцев назад

    Hey man, thanks for this video! It helped me to put the different values into perspective, while I wait for the next appointment. Other introductory texts on random articles did not give examples of ranges and their possible diagnoses and seriousness. Stay safe folks

  • @maril1379
    @maril1379 Год назад +3

    Easy to understand. Thank you so much! Thumbs up

  • @maril1379
    @maril1379 Год назад +2

    Excellent thumbs up.
    Easy to understand!

  • @shile3
    @shile3 7 месяцев назад

    Surfing through the entire web and found this super informative video that rid all of my question marks…Awesome!!!🎉

  • @anter881
    @anter881 Год назад +1

    Once again, great video!

  • @newyork4198
    @newyork4198 11 месяцев назад +7

    CRP of 205! Was dealing with bouts of urticaria for about 2 months (not sure if it’s related), then one day I noticed 5 bug bites on my right ankle. Fast forward a week and my legs were sore like I had a tough workout. A few days later I couldn’t walk without taking 800mg of ibuprofen several times a day. A few days after that my feet, calves, hands and forearms got swollen and stiff. A day or two after that the stiffness went to my jaw and I had a fever. Went to the hospital and got that CRP number there.
    Finally see my doctor as well as a rheumatologist and hematologist. Believing it was Lyme (even though I tested negative, and the bites didn’t look like tick bites) they put me on doxycycline for 6 weeks. After day 3 on antibiotics, my symptoms started subsiding.
    Thoughts? My doctors haven’t a clue. Rheumatologist thinks I have RA, but when you’re a hammer, everything is a nail.

  • @rjworldvlog2024
    @rjworldvlog2024 Год назад +2

    Thanks a lot!

  • @mltlecturesacademy
    @mltlecturesacademy Год назад

    nice information

  • @Berley_1234
    @Berley_1234 5 месяцев назад +1

    my hsCRP is almost 30 !! i am in line for a total hip replacement and praying hte CRP will lower when that hip is gone.

  • @murarirajagopalan3771
    @murarirajagopalan3771 8 месяцев назад +1

    How about CRP s along with CBC and ESR ?

  • @yahyakhan9448
    @yahyakhan9448 6 месяцев назад +1

    Is high crp cause left hand arm chest pain also on right side sometimes and left leg

  • @surjitsingh8575
    @surjitsingh8575 Год назад +1

    Hello Dr
    Whats the normal CRP in One year old baby ?

  • @free2bkittenforever
    @free2bkittenforever 8 месяцев назад +1

    what about 86 2 months after recovering from infection?

  • @parminderkaur9902
    @parminderkaur9902 Год назад

    Sir my crp value is 67,I was hyperthyroid patient

  • @machietheapachie7214
    @machietheapachie7214 Месяц назад +1

    I've just done a 3-4 month carnivore diet and my C Reactive Protein has leapt from 0.6 mg/L to 10.
    That said, everything else from thyroid to lipids improved.
    What do you make of that? 🤔

  • @shahidulrehman574
    @shahidulrehman574 6 месяцев назад +1

    My crp test shows 16.3 what can i do

  • @juttudevaki5471
    @juttudevaki5471 Год назад

    My CRP is 48 in my first trisemister.. how to reduce risk to my baby

  • @parminderkaur9902
    @parminderkaur9902 Год назад

    Sir please something suggest me I am hyperthyroid patient and I am under weight ,iam 38 yrs old and weight is 49

  • @melanalponsu
    @melanalponsu 6 месяцев назад +1

    Hi Doctor my daughter got influenza just recently and now she is having high CRP which is 117 and after the antibiotics treatment it went for 6 but after 4 days agin it went for 49 she was ok for few days but now agin she is getting fever every 12 hours . Now doctors are giving another antibiotics so far it’s remain 40 didn’t come down . Is there anything that holding this ? It’s been 5 days with the new antibiotics. . Thanks for your help to the world . Just wanna check if this kind of situation what we should do

    • @makemeglow5091
      @makemeglow5091 6 месяцев назад

      hey how is your daughter?...my daughter who is 6 years ,got unexplained fever and after 3 days they started antibiotic injection...Her crp and wbc was high...and mild infection on tonsil ...now she seems ok but i am worried that it will come back like as you said

  • @ullasv
    @ullasv Год назад +3

    So CRP below < 20, is viral or bacterial infection?

    • @003halmr
      @003halmr 9 месяцев назад

      Its impossible to say. CRP only indicates that there is inflammation (or another trigger of IL-6 such as cancer). It tells you that something is going on, not what is going on. The doctor in this video suggest a high CRP (such as >100 mg/L) is more likley to be bacterial than viral but still there are many caveats. A severe virus or even cancer and blood clot or even something like rheumatoid arthritis can increase the CRP. Important take away is CRP ONLY tells us there is something going on, not what is going on. CRP is part of the picture but you will need a doctor to interpret all that is going on.

  • @jadeedgrouptaxdepartment8042
    @jadeedgrouptaxdepartment8042 Год назад +3

    My CRP is 48, dr suggest me cefexime antibiotics

  • @padraig9445
    @padraig9445 Год назад +3

    Can CRP >50 be a sign of STI

  • @muslimdiary4698
    @muslimdiary4698 11 месяцев назад

    Sit my crp is 87mg/l and Tlp is 47.first i use ciprofloxacin for 3 days but not doing will not i am using azithromycin 500mg two dose used till not but still temperature episode continues.pls advice me

    • @sohailshaikh4495
      @sohailshaikh4495 9 месяцев назад

      Hiie .. how are you now ... Is you fine now ?

    • @sohailshaikh4495
      @sohailshaikh4495 9 месяцев назад

      What you did .. ?

    • @9doyouknow09
      @9doyouknow09 20 дней назад

      Are cured completely? My sister also got 87 crp ...She also has continuous fever..when you get cured?

  • @mad_medico11
    @mad_medico11 Месяц назад

    16

  • @tusharambuskar3200
    @tusharambuskar3200 2 месяца назад

    My 4.5 year old son CRP count is 89 and he is admitted to hospital and he is facing recurrent fever of 101 to 103* degree on second day also the antibiotic treatment is goin on but no satisfactory results yet please suggest what i can do

    • @9doyouknow09
      @9doyouknow09 25 дней назад

      Hello sis..how is your son health is now? My sister also facing the same issue..is he cure? How many days it takes? Pls reply

    • @9doyouknow09
      @9doyouknow09 20 дней назад

      Any update?

    • @tusharambuskar3200
      @tusharambuskar3200 18 дней назад

      @@9doyouknow09 it took him 6 days to recover

  • @MrAbdulmech
    @MrAbdulmech Год назад +1

    My CRP IS 127 Mg/dl I suppose it’s really bad what could be cause

  • @maryb732
    @maryb732 Год назад +3

    My CRP has been 4 mg/L. The lab flagged it each time over the last 9 months as having a High probability of cardiac event or stroke. I AM A VERY HEALTHY, ACTIVE 60 y/o FEMALE. The thing is, I have NO heart issues, low BP, low cholesterol, etc. All lab results normal except Crp any thoughts?

    • @HeatherF99
      @HeatherF99 Год назад +3

      The vaccine?? Just a thought 🌞

    • @johnow7
      @johnow7 9 месяцев назад

      Was it High Sensitivity (HS) CRP or just a CRP?

  • @Deanpeach
    @Deanpeach Год назад +1

    Over New Year I had a fever, sickness and cough. I was given antisickness medication, pain relief and antibiotics through IV and my CRP marker was 342 when I was admitted to hospital and given antibiotics... They said it was a viral infection and were concerned about sepsis, is this a legitimate concern??

    • @Sickshitmofaka
      @Sickshitmofaka Год назад

      How are you today? My wife has the same situation

    • @Deanpeach
      @Deanpeach Год назад

      @@Sickshitmofaka I’m sorry to hear that! I hope she recovers quickly!
      I have since recovered fully, they couldn’t tell me what the infection was but after doing a small amount of research it seems I was lucky to have gone to hospital when I did!
      Is she being taken care of? She may need antibiotics

    • @sohailshaikh4495
      @sohailshaikh4495 9 месяцев назад

      Now how are you ?

    • @Deanpeach
      @Deanpeach 9 месяцев назад

      @@sohailshaikh4495 I'm fit and well thank you!

    • @ujjwalgupta2944
      @ujjwalgupta2944 8 месяцев назад

      My doctor told me the same ...that viral infection is the reason for my high crp level...fever was continuos for 10 days ...are u fine now ?

  • @mokalify
    @mokalify 10 месяцев назад

    my crp is 8.3 mg/L is that bad ?? since they highlighted it as high

    • @003halmr
      @003halmr 9 месяцев назад

      No thats not bad. The upper limit in many countries is 8.0 mg/L. See a doctor if concerned.

    • @misfitm1457
      @misfitm1457 Месяц назад

      Normal but to get a result you must have a Dr who would contact you if it wasn't?

  • @marwan2367
    @marwan2367 Год назад +4

    my Baby crp level 20 4 days old,What should I do,plz

    • @kishanamoli9710
      @kishanamoli9710 Год назад +1

      How's your baby now

    • @marwan2367
      @marwan2367 Год назад +1

      @@kishanamoli9710 Thank God, he is healthy

    • @kishanamoli9710
      @kishanamoli9710 Год назад +1

      Marwan may i know symptoms and treatment what doctor gave him

  • @kishanamoli9710
    @kishanamoli9710 Год назад

    Dear sir, my baby 4 years old, having fever almost from 10 days, after test crp was 19 doctor gave Amoxicillin Antibiotics syrup and perecetmol syrup and one medicine for infection.
    But medicine no more work, fever coming and going only gap of 2 hour's.

    • @EesaShahzaib
      @EesaShahzaib 6 месяцев назад +1

      After how long your baby recover?? Please reply

    • @kishanamoli9710
      @kishanamoli9710 6 месяцев назад

      @@EesaShahzaib take take some days but medicine was continue 10 days.
      Go to child spacalist....never go to any other doctor if kids are sick.
      Cox only a babies doctor can decide dose of medicine and perfect treatment for kids

    • @velusamypothiraj2300
      @velusamypothiraj2300 6 месяцев назад

      Any update mam

    • @EesaShahzaib
      @EesaShahzaib 5 месяцев назад

      @@velusamypothiraj2300 he was hospitalised for some days now he is doing good

    • @9doyouknow09
      @9doyouknow09 25 дней назад

      Why no one is replying?

  • @jharnadasukil2550
    @jharnadasukil2550 Месяц назад

    My babies crp 34 age 3month why should do I plz

    • @misfitm1457
      @misfitm1457 Месяц назад

      Contact the babies Dr of course, but as they did the test they should already have said what, if anything, to do

  • @AbdulWahab-hk8up
    @AbdulWahab-hk8up 10 месяцев назад

    My CRP is 6.56

  • @benberkovic
    @benberkovic 5 месяцев назад +2

    I just got my blood tests back, after a continuing 4 days of high fever and right abdominal pain, and my CRP is at 103.
    My GP told me to go the infectious hospital to see what it might be, but she says she suspects it's covid.
    I've also had a gray stool, and from all the other symptoms and my not best lifestyle, is it possible this is not covid, but liver damage? I tested negative for covid 4 days ago.

    • @9doyouknow09
      @9doyouknow09 25 дней назад

      Was it cure? My sister also high fever and crp and abdominal pain..