Ketamine and Depression: From Despair to Hope in Hours - Carlos Zarate, NIH Clinician Scientist
HTML-код
- Опубликовано: 20 сен 2024
- Read his story: www.irp.nih.gov...
Carlos Zarate, M.D., speeds up treatment for major depression at the National Institutes of Health (NIH) Intramural Research Program (IRP). Dr. Zarate is Chief of the Experimental Therapeutics & Pathophysiology Branch and the Section on the Neurobiology and Treatment of Mood Disorders at the National Institute of Mental Health (NIMH).
"Let's create a drug that works great for depression, but let's make it so expensive that only the rich can get it"
Hey, so find a place that couples it with psychiatric care, it's all about the billing. My insurance reimburses me bc part of the bill says psychiatric care, so I'm only paying like $150 per session versed the $250 he charges. And I use my FSA to pay for the rest of it. This is for my infusions... But I have a Dr. I can suggest if Youre interested, he gives troches (at home sublingual). I see him once a month ($125 for virtual visit) and I get a month's worth of troches to be taken every 3 days ($45 at my compounding pharmacy). It's affordable and absolutely worth it .
not true lol, i do k daily in my own home, lol
Ill refer you to this mate online you can purchase from
Mycodre7---¿
Hes on instegram
I want to try it. I'm 52 and have had depression/anxiety since I was 5. Nothing really helps. I've been hospitalized so many times
What’s the @?
Dr Zarate, your research saved my life. Thank you.
I am so grateful for this. It has saved my daughter.
I've had five courses of electroconvulsive therapy for severe, treatment-resistant depression as well as having tried nearly all the antidepressants on the market to no avail. Only ECT and ketamine truly helped with my depression, and I'd recommend that ketamine be more available to the severely depressed as it has helped me a lot.
How was your experience with ketamine.. was it helpful..has it any side effects.. plz let me know.. I am struggling with depression for two years
@lydialoud How about TMS , Trans Cranial Magnetic Therapy, brain is MRI'd and they locate the area of the brain by laser the area to be treated is aspecific point like PTSD or Chronic Pain, Depression etc, please look itup
Just had my first treatment, honestly I felt WORSE afterwards ans the next day...but by day 3 I had this bizarre clarity on everything...I was still very depressed but I all of sudden could easily verbalize and point to the things that were causing me to feel depressed, things I hadn't confronted or even thought about despite decades of severe depression...all of a sudden every the stressor became so much easier for me to verbalize what they were, where they came from...now, I do NOT feel any less depressed because these things still exist, but the fact I can see the roots of my feelings more clearly is a big step...many more treatments to come, I'm hopeful that a means of coming to terms with and attacking these issues will slowly become more apparent to me...this is tje most progress I've ever made tho
Congratulations! Thanks for telling me.
I had a similar experience . It was weeks and even months later that I felt the most benefit
@@markmasters9641how you doing now?
Updates?
Ketamine is a powerful dissociative with a potential for abuse & addiction. Psilocybin is far more safer & effective.
I just had a minimally invasive spine surgery and they gave me ketamine for pain instead of Opiates due to me being on Suboxone because of prior addiction issues, the Ketamine was given along with the anesthetic they used to put me under, after the surgery I felt amazing, had to fast before hand and in the recovery room they gave me animal crackers and coffee, it was the best meal I ever had ! I'd love to try this therapy because I deal with sadness and depression, but I'm sure it's very expensive and not approved by medicare insurance.
Approved by insurance now
There's absolutely no reason whatsoever this drug should be expensive
Repurposing an old scheduled veterinary drug like ketamine is great work.
Yep just like repurposing sodium fluoride which was a toxic waste now it's a water treatment From Municipal Water Systems and Gerber baby water
Wish I could try this. I was diagnosed with manic depression/bipolar disorder and panic disorder and have tried over 13 meds and now I am just struggling with no meds. It's a daily struggle to survive.
Hang in there
You’re not alone. You are loved and never forget that how you feel is so much more common thank you’d ever think. I myself fight a battle with panic disorder everyday. Bless you and have faith, one day at a time
Me too
pm me homie, i was in the same boat and i found k myself.
Drive to a clinic. It could save your life.
Best thing I ever did. I participated in this clinical trial and it changed my life. I had Dr. Zarate and his team and they were great!
If you are not acute suicidal waiting 6 weeks so that antidepressants kick in is ok. I have mdd for years but all the antidepressants do not work this is where Ketamin comes into play. Although I think other forms of depression should be treated with ketamin.
Amazing 10 years later and you ended up being right Ketamine is much more widly available for depression in the US than it used to be.
I worked for a Veterinarian and we had katamin sitting around everywhere, it was cheap. ($30/vial)
Is there a controlled environment to try mushrooms?
@DavidMcKenzie-xb5ny can you tell me what dosage please? Thank you 😊
Depends of the strains
With Cubensis 5g dried@@sadpatriot5199
Did it several times in Chicago at iv solutions and I can say it does nothing for my type of depression or anxiety but it did heal nerve pain so
Have my first infusion tomorrow, hopefully it helps 🙏
I have my first one this coming Friday. I am excited, scared, and reserved at the same time. I dont want to get my hopes up and end up being a patient that doesn't respond well to the treatment. I haven't responded at ally to any form of treatment for the last 5 years. 2 hospitalizations and daily SI. My wife came to me and told me she wanted to look into alternative treatments. This is our first one and I hope it goes well. I hope yours goes outstanding! If there is any way you could relate part of your experience I would greatly appreciate it. It doesn't have to be personal in nature but there are a lot of doubts and sleeplessness nay my wife and I until Friday. I hope for the best for you.
@@aaronhommel4615 I had the infusion. During the procedure I didn't feel a lot, like impaired, but after I found the heavy feeling in my chest slowly start to leave. My thoughts were and are clearer, I find myself caring more about my loved ones and their needs, and when I try to lapse into old thinking I feel the same urge, but I can choose to let it not control me. I also feel a general sense of "peace" and "wellbeing" I guess, and I feel like going out and doing things again(previously hated going outside and was a complete shut in). I have my next infusion in a few days, I'm excited. I really hope it helps you as well!!
How was your experience with ketamine.. was it helpful..has it any side effects.. plz let me know.. I am struggling with depression for two years
@@aaronhommel4615 How was your experience with ketamine.. was it helpful..has it any side effects.. plz let me know.. I am struggling with depression for two years
@@ahmedfraz8324 hello, thank you! It has been 2 months now and I've since had 10 infusions and it has helped immensely! It does makes very disoriented and I do get anxious when I have an infusion, but I've learned to handle it. I also usually feel a bit nauseous and maybe a little woozy when I'm done, like a feeling of being drunk, but no long term side effects and it's made my depression much easier to understand and deal with, I also have significantly less of it
going through those first weeks is horrifying...and then to find that it doesnt work... then the withdrawal process,and restart a new one....if someone comes up with a wonder drug...they will be v rich
Why add be very rich.? It should be their solomen duty to assist people.
This was 10 years ago. Where is the better treatment? I need it please.
I start my first treatment Friday. I pray that it works.
Please post an updat
Hey dude update? I've been fw dxm but stopped after overdose but want to try this because it was pure bliss before I over did it
I hope it did god bless
How is it going?
Ketamine did not work for me. Neither did ECT or antidepressants. Only thing that kinda works is just trying to be positive. I started reading again and that brought some joy but everyday is a struggle. I try to plan adventures with family and just think about things that use to bring me joy.
This is what infuriates me with the fda..this needs to be standard for treatment..but than pharmaceutical companies would lose so much money on pills.
Thanks to our for-profit healthcare, countless people suffer. It's a disgrace, to say the least.
I've suffered depression and anxiety for years. Also moody all the time. Been diagnosed with depression anxiety suicidal ideation and bipolar 2. All this has turned into despair for the last 5 years. I am to the point I don't care if I live or die. To me life is not worth the aggravation. And every time I want to try anything besides antidepressants or antipsychotics it's too expensive or my insurance doesn't cover it. I live on disability which is hell to live on so little. I even tried ECT which I regret. IAM hoping I can try the ketamine if they take my insurance. Otherwise I see my life ending sooner than later. Ive tried so many things and feel hopeless and helpless.
You need a friend?
I know you're pain...
It's a miserable existence.
Same thing.
My depression isn't aggravation. I'm completely disabled.
I've tried EVERYTHING - medications, TMS, TBS, ECT, Ketamine Infusions (low dose) and nothing has helped me...
It's like living with black concrete in my head, and a black garbage bag over my head and suffocating me...
It's ungodly to experience....
I'm praying that God forgives of all my sins while I've been living with depression, as I haven't even known what is real and what's only my world...
I pray Jesus keeps His promise to me when I have been disobedient myself, due mostly by simply meditating my treatment resistant depression.
I wanna experience God, and experience happiness and joy, every lasting...
google 'American Society of Ketamine Physicians', infusion cost range from 350-1000, insurance may cover a portion or will in future
@Karicat Watts infusions are 1/20th dose of recreational, are done after a thorough medical history and in clinician's office to monitor.... and do not cause hallucinations etc. It's not getting high or euphoria, it's helping rebuild synapses and restore healthy brain pathways which is the opposite of the recreational effects
@@thesummerland6165 I am areliable ketamine supleir bothliquid and powder. Hit me up if interested in getting some.
Wickr...pillsmethpack
Whatsapp....+14062909815
Telegram......+14062909815
FYI: There are websites where you can talk to a doctor online and get a ketamine nasal spray in about a week for a total of $450. including doctor visit and web site fee. I have tried the nasal spray twice experimentally (one spray in one nostral once and one spray in both nostrils another time) and not noticed any shift but they recommend two sprays in each nostril and I have not tried that yet. This is vastly cheaper than an in-clinic appointment of $1,200. and supplies more ketamine so it may help others.
@danerose575
It's quite true...
I got a ket nasal spray online from
Dennis_allen_01..
I live in Ohio...👌
He is on Instagram..
Quite cheap and affordable.
When I say “ketamine” - the sound comes out of my mouth and it hits the other person’s ear, travels through this byzantine conduit in their brain, through their memories of ketamine or lack of ketamine, and they register what I'm saying... and they say yes they understand, but how do I know? Because words are inert. They’re just symbols.
I am starting ketamine therapy this Monday. Extremely anxious and suicidal, I'm at my last stop. Have done ECTs, on/off roughly 20 meds, on/off benzos (still dealing with some withdrawals). Even been in-patient 5 times over last year and half. Only thing I haven't done is TMS. I wake up every night in a panic, only getting 2-3 hrs of sleep on avg.
How is the ketamine therapy going for you? hope you can get some Release of it
I hope you are doing better now! ( I know this pain all too well..really want to try this.)
@@tusharchaudhari1429 i start mine this monday for depression. how is it working for you?
Dave Blasko, your describing the debilitating benzo withdrawal symptoms or Benzo Tolerance Withdrawals (from taking prescribed dosage.)They can last for years you know. Why hasn't any Doctor told you that. Your going to allow the Doctors to kill you if you continue with all these 'treatments'. They're not treatments, their neurotoxic drugs/poisions, ECT's murder part of your brain. A very, very slow taper off ALL the shit you're on and you'll find a human being under there. One that isn't suffering endlessly & needlessly anymore. You're allowing Psychiatry to literally torture you to death.
@@tusharchaudhari1429 I don't mean to laugh here, because we know you're trying to help...
Although homeopathy is like shooting a pellet at an armored tank, when talking about his level of depression and anxiety, etc.
This looks great hope it doesn't turn out to be the great revolution that the SSRI's were supposed to be !!
I am positive that with future research we will eventually find a medication that works !
A couple of years I need them now
+Paddy Brady: Depending on where you live, there are clinics that are offering this treatment. Unfortunately, because these treatments have not been officially approved by the F.D.A., I think the clinics only take cash or credit cards. Medicare and Medicaid won't cover treatments and that sucks for someone like me who relies on Medicare. OR, you could get into a study somewhere. Try looking at ClinicalTrials.gov to maybe find something in your area.
+Paddy Brady I live in Birmingham, Al and I will be starting my first Ketamine treatment in 2 weeks at The Univ. of Al at B'ham under Dr. Shelton via one of the six Ketamine studies he is conducting at this time! I pray you too can find such a program, if not try the one at UAB that I am doing if you can! God Bless and good luck!
Call doctor Hannah at Florida spine institute. They are cheap they charge I believe 250 for depression per infusion.
Got ketamine available both liquid and powder pm me if you interested in getting some.
Wickr.. pillsmethpack
Whatsapp....+14062909815
Onlineshopchemicalss.com
It is good to taste /ketamine 500mg/ visit our website:Buymedshoper.com
I wonder if Ketamine is available on the NHS now. I have tried every antidepressant over the years and none of them work for me.
Darling antidepressants is more like a preparatory drugs for suicide, antidepressants cost alot of damages on my friend and we are spending more on ketamine infusion.
But someone advised we try psilocybin capsules and is a miracle to us!
You can as well give it a try.
I would suggest you reach out to Dr. charles popularly known as charlesmyco_
On instagram.
It is no measure of health to be well adjusted to a sick society...........Krishnamurdi
Why not just buy an acid tablet? What the hell is the difference? Legality?
Now its not so bad as far as price and it truly works.
There are alot of medicine with acute anti depression effects , unfortunately those are always drug of abuse like opioides .
Does medicaid pay for this? If not, what private insurances cover the cost? I am in NYC and the cheapest I can afford is blue cross/shield which is $480 monthly. Anyways, it doesn't help me feel better anymore knowing that there is help out here. I was very enthusiastic and happy about getting help during my young adult years but my depression has gotten so bad as I got older I seriously need this treatment. Can anyone else agree that their depression has gotten worse as they were aging? Anyways, just knowing we have new treatments options being developed is what's helping to keep me alive. I just wish I could feel hopeful knowing this but as I said, my depression has gotten so severe I have to force myself to feel this way and I can't even make sense anymore so I apologize if this post sounds dumb.
for me depression has also def got worse with age so far
Sawyer Rice Sorry to hear you are going through this shit. But weare strong. Don't ever give up
yes we are
of course they dont.
I am actually thinking about getting this by other means and figuring out the dosage that way
I'm supposed to start ketamine troches soon (Really low dose). I have bad dizziness most of the time and, wondering if anyone noticed if ketamine has helped with that? I have TRD / GAD and, some SSRI meds would take away almost all of my dizziness. (For me, it's definitely related to anxiety). The effects don't last but a month and, I'm back to feeling really dizzy. What I'm hoping is if I start out slow, the dizziness will go away. From there, I'd be able to handle to take higher doses.
Has anyone else had issues with that and it made them less dizzy? That's what I'm most worried about. It's hard to find someone with those specific issues. I'm running out of treatment options. (Tried meds/TMS/therapy)
@akengozi4430Uhhhhh, No thanks. I'll pass on something like that. I decided on an actual clinic that can do the treatments and, not troches. I want to do it the proper / legal way. I may not figure out the dizziness issue but, they said I could try a smaller dose, and go from there.
With the smoking of opium, all my depressive symptoms disappeared. But it's addictive and I have to take it every day.
Who won the world gives you opium to smoke every day. I can’t even get a doctor to prescribe anything for my pain
Yeah… I find that a little crack cocaine can be helpful in treating my mood swings. I’m often lethargic or depressed. The hard white really wipes the cobwebs away and makes life bearable.
Where can i get it?
Here is to hoping
Some large foundation and or the government ought to fund a huge human trial study with Ketamine for depression. Ideally,a more affordable ways of precisely administering the medicine can be developed. May a special nasal spray apparatus. Ok. My "on the cheap" treatment would now costs me less than $5 a session. But I would happily pay for a something like a precisely measure throat mist. Or a sublingual pill with the exact dosage for my weight.
Cary Costner Great ideas!
Fernando Peña 'ketamine din,t work for me
Passed out during a treatment
This comment aged very well. Seems this guy was a genius. Nasal spray? Exactly.
please help... I have been depressed and frequently suicidal for more than 10yrs.
Unless you have $3000 no such luck.
fees range from 350-1000 per infusion and some do not charge for an intake. If you google 'American Society of Ketamine Physicians' you can find. Insurance may cover at least a portion in the future as it works for many.
@@toddstarks226Depends in which country u live in! I believe this ketamine therapy is free in Canada in some clinics!
“A handful of hospitals ( in Canada) have begun setting up grant-funded programs that are free to patients, but the waiting lists can be months long. “
Otherwise, it says, it’s $4,700 Can for the weeks-long treatment! The prices may vary somewhat from a clinic to clinic!
One has to come back for a follow-up ‘top up’!
It is best to go to the professional official medical clinics in the hospital not just any ‘fly-by-night’ mall ‘clinic’, no matter how many ‘positive reviews’! I just read an article about someone going to one of these casual ‘wellness’ clinics , being traumatized by the experience! It seems he was given too much ketamine and was left unsupervised in a room!
Ketamine did the opposite for me. I had to stop. Not doing that again.
Hopefully for the public & ‘affordable’
I do purchase mine from this doc online..
Mycodre7---¿
Hes on instegram,
No chance they're going to just start handing out quick acting antiquated anaesthetics any time soon .they put a stop to benzos and shit years ago .
@Digitaldischarge2331
Too bad benzoz are quite unaccessible to the public...I still get mine from an online store..
Dennis_allen_01
He sells and ship discreetly too👌
He is on Instagram
circumstance. And IV ketamine did nothing for me.
Damn auto correct
Spravato is what I meant
Then you need the help of a professional Psychedelic administrator..
Dennis_allen_01 helped break free from addiction 2 years ago, using Psychedelics..
He is on insta💯👌👌
People please eat healthy, exercise and go to church.
OK! All good and basic! And then..?? Doing these things will not cure the debilitating chronic depression! A friendly church might help with isolation and loneliness! At the same time, many severely depressed people would find it difficult to attend any function, to leave the house!
I know u mean well! Yet, u are showing a complete lack of understanding the nature of a clinical depression!
Not everyone depressed is clinically depressed! There are situational depressions, such as a death of a loved one or living through a traumatic event, etc!
The clinical depressive disorder is an illness that is often chronic or regular episodes with some normal periods in between!
One does not cure the MS or a genetic heart condition by going to church or eating healthy! Eating healthy is important and helps some, but won’t help the depressed people function!
Please, do try to educate yourself on the topic! Many articles and books out there to help u understand! Also, talk to people that have this illness!
#MentalHealthAwarenessMonth: Watch #NIH IRP #researcher Carlos Zarate, M.D., explain how he and his team are developing faster treatments for #depression. bit.ly/1GjvnvO
its too expensive though.
There are hospital clinics that give free treatment in Canada! They are run by Grants! Longer waiting time, though!
@@jbeachboy100Some medical hospital clinics are run by Grants, give free Ketamine therapy treatments! In Canada! Maybe also in the US?
Monosodium Glutamate (MSG) They put it in your food, its a drug!
There is probably a ketamine clinic within 20 miles of your home.
Didnt work for me
I'd appreciate your comment
I bought some psychedelic product from a drugstore online they're very reliable ship discreet
They're on INSTAGRAM
@@kennedygary9031This is so dangerous when not done under the medical and professional supervision, without any pre, during and post- infusion Ketamine counseling, preparation and therapy!!
Some people were traumatized when they took or were given a wrong Ketamine dosage or took mushrooms, without the experienced professional and medical support!
well that was short and sweet...👎..be very very careful with what you put in your body....this treatment is not for the fainthearted..gruelling..distressing..and with an uncertain outcome..prob only for drug resistant sufferers..
Is this treatment available in India?
ranjit misal yes NIMHANS Banglur .
Hope the make new drugs
Hope god demolishes all
All drugs all pain that we failed to defeat the one who lives to close
All for the money so hard for the money STAY AWAY FROM DRS
Ketamone works great.
I'd appreciate your comment.
trippy_psyche01¿.
They're on INSTAGRAM
How many treatment in total
SPONGEBOB ME BOI, I HAVE OVERDOSED ON KETAMINE AND AM GOING TO DIE
ARGHHAGHAGHAGHAGH