The Shape of Discovery: Ketamine for Treatment Resistant Depression

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  • Опубликовано: 12 июн 2024
  • Dennis S. Charney, M.D. the Icahn School of Medicine at Mount Sinai received the BBRF Colvin Prize for Outstanding Achievement in Mood Disorders Research and presented at the Brain & Behavior Research Foundation 2019 International Mental Health Research Symposium in New York City.
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Комментарии • 157

  • @scf7334
    @scf7334 3 года назад +60

    Ketamine has literally saved my life. I’ve been doing infusions for almost two years. I’d been on a million medications, tried transcranial magnetic stimulation, electroconvulsive treatments and went through years and years of therapy. Nothing has helped like ketamine. It pulled me from the very darkest place I’d ever been and did it quickly. I’ve been functioning at a more healthy level than I have in over 20 years. I’m so very grateful.

    • @jonnyw82
      @jonnyw82 3 года назад +5

      Congratulations! That’s so awesome. I’m going in next week for my first infusion🙏

    • @JohnSmith-ys4nl
      @JohnSmith-ys4nl 3 года назад +3

      That's great to hear. I have bipolar and wonder what the efficacy of ketamine is for that.

    • @jinkledinkle8423
      @jinkledinkle8423 3 года назад +1

      @@jonnyw82 How did it work out for you?

    • @jonnyw82
      @jonnyw82 3 года назад +8

      @@jinkledinkle8423 Ketamine indirectly decreased my depression symptoms by drastically reducing negative chatter in my head. I still have to be on guard and make sure I'm not dwelling on negative thoughts etc. but it's much easier now. My wife went with me on all my sessions and after the first one it opened me up emotionally so much that after the session I was crying asking my wife to forgive me for being such a shithead to her. But I didn't feel self conscious at all being so emotional, it felt good to be that open. It's a huge commitment bc you're supposed to have 6 sessions within 10 or 14 days and I was pretty wiped out each session bc of nausea and just feeling pretty spacey. So you basically have to set aside the 10-14 days because you can't go to work or even drive afterwards. I pray you will have great results if you plan on doing this, best of luck to you.

    • @jinkledinkle8423
      @jinkledinkle8423 3 года назад +2

      @@jonnyw82 Thanks for answering, hope it will help me too. Best of luck to you as well!

  • @icnohelp
    @icnohelp 3 года назад +14

    Thinking outside the box. That's how new discoveries are made.

    • @anhumblemessengerofthelawo3858
      @anhumblemessengerofthelawo3858 3 года назад

      _You would be pleased reading the groundbreaking book "The Structure of Scientific Revolutions"._
      _To wit -- ketamine itself ... was discovered accidentally (serendipitously!)_
      _Groundbreaking book_

    • @TheRusschannel
      @TheRusschannel 3 года назад

      yeah at $5,000/mth its amazing isnt it LOL

    • @EvLMusHroOoM
      @EvLMusHroOoM 2 года назад

      Amen 🙏

  • @sherrijensen3427
    @sherrijensen3427 2 года назад +5

    I have been on 3 now and it is wonerful worth the money.

    • @chrismcdevitt7814
      @chrismcdevitt7814 2 года назад

      I'm glad it's helping. Keep us informed, because this has been a 20 year battle for me with depression . I'm considering this.

    • @AGBolish
      @AGBolish 2 года назад +1

      @@chrismcdevitt7814 Hi Chris, I’m not sure if you’re still looking into it, but I just took the plunge into IV ketamine and it has changed my life already after just one dose. I was able to evaluate why I was so sad and it revealed a lot to me. Good luck!

    • @chrismcdevitt7814
      @chrismcdevitt7814 2 года назад

      @@AGBolish Thanks ! I still am. I'' m going through the clinics process as we speak.. I'm glad it helped. It gives me hope.

  • @jeremyncrm2012
    @jeremyncrm2012 4 года назад +25

    I’m grateful for this research, I suffered with treatment resistant depression for 15 years, and was suicidal when I learned about ketamine and found a clinic to receive it. I’ve been receiving treatments for almost 9 months and it has been life changing. My depression has lifted almost entirely, I define myself and my life differently, I have energy to engage in life, etc. it has been a miracle for me

    • @robbietucker9283
      @robbietucker9283 3 года назад +2

      I'm glad you found some relief. I'm checking into it for my clinical depression I've been battling for 30 years now. I'm hoping I can receive the therapy even though I'm currently on methadone maintenance for opiate addiction. I've been stabilized several years and am actually weaning off the medicine but I'm worried it might prevent me from being able to do it if I let them know.

    • @jeremyncrm2012
      @jeremyncrm2012 3 года назад +1

      Robbie Tucker I think a lot of it has to do with the doctor or clinic that you go to, my doctor actually uses ketamine to not only treat depression but also to treat addictions, I know alcohol and cigarettes, I’ll ask about what he thinks about treating someone that has been coming off an opiate addiction and let you know what he says.

    • @robbietucker9283
      @robbietucker9283 3 года назад +3

      @@jeremyncrm2012 Thanks for the reply. I actually had my first infusion today. It was quite an experience. I can definitely tell already that my mood is lifted and there is less internal chatter going on in my head. I go back in two days for my next one. Looking forward to feeling better.

    • @jeremyncrm2012
      @jeremyncrm2012 3 года назад +2

      Robbie Tucker glad to hear it, I hope it went well, it is quite the experience.

    • @georgesmajerus3272
      @georgesmajerus3272 3 года назад +1

      @@jeremyncrm2012 hello, that is helping each other. Me self, in France, I have that problem of telling or not some information to doctors. I have 40 mg of oxycontin since my operation. So the good thing about ketamine is the pain relief and the lowering the morphine (oxycontin). I just survive with 40 mg. No feel good at all. But to make it more comfortable, I think the dosage will increase dramatically. Every waking up is horrible. I ask the question :is it the need for the drug that makes me getting out of sleep, or is it the metabolism change from sleep to awake? I have tried some tricks to find out.... Thanks for your attitude. Courage too all

  • @RealGirlLive
    @RealGirlLive 3 года назад +28

    Ketamine has been the only thing to work for me and I’ve been on celexa, Prozac, Wellbutrin, and Lamictal. The only problem is my ketamine prescription isn’t covered by insurance, so now I’m trying a tricyclic. It’s too bad that the medical industry is profitable. Health care should be a right.

    • @RealGirlLive
      @RealGirlLive 3 года назад +1

      @Ilir Cami the tricyclic had me feeling like a zombie so I’m back to paying $350 out of pocket for the intranasal ketamine prescription

    • @anthax908
      @anthax908 3 года назад +2

      @@RealGirlLive just buy it elsewhere

    • @TheRusschannel
      @TheRusschannel 3 года назад +1

      get it compounded (secret trick) legal and $5/dose

    • @ahmedfraz8324
      @ahmedfraz8324 2 года назад

      how was your experience with ketamine..was it helpful..has it any side effects.please let me know..i am struggling with depression for four years..how long it takes to cure depression

    • @franciscoruiz9824
      @franciscoruiz9824 2 года назад

      @@RealGirlLive q sensacio te causó la ketamina

  • @joseph8468
    @joseph8468 Год назад +1

    Thank you for this information.

    • @joseph8468
      @joseph8468 9 месяцев назад

      @@hopebeel8765 I hope that they work well for you. Best of luck.

  • @mtorres4445
    @mtorres4445 Год назад +1

    I pray that insurances figure out that they are spending all this money on medication when it is cheaper to just prescribe ketamene. They have paid more for my doctor visits, ssris, anti anxiety and off labeled medications like Prazison (PTSD flashbacks ) in money than they would iv ketamene which literally saved my life when I finding my 18 year old son dead just sent me into a mental crash and saved my life in 12 hours (from suicide). I have had to do more than the 6 to 8 treatments but I have far more trauma than just finding my 18 son dead. This is a new medical discovery but literally work within hours, especially for suicidal thoughts, PTSD and so much more and NOT ADDICTIVE.

  • @tbay1795
    @tbay1795 2 года назад +1

    I have my first treatment tomorrow.
    I hate to put too much hope I’m this since nothing has ever helped before but I guess that’s the nature of the beast.

    • @AlextheGill
      @AlextheGill 2 года назад

      Would love to hear how your first session went. My best friend is deciding whether or not to start hers soon.

  • @ramanathannarayanan4265
    @ramanathannarayanan4265 2 года назад +2

    Any clinic developed and giving Ketamine treatment in India?

  • @mwwhatever
    @mwwhatever Год назад +1

    I've tried probably 25 different antidepressants over my life, none of which have really done anything. I was told that I might be able to try S-Ketamine. I've waited over a year and seems like it's just not going to happen. I'm sick of trying

    • @jamesbryson9542
      @jamesbryson9542 Год назад +1

      Joyous Ketamine online is $129 a month.

    • @mwwhatever
      @mwwhatever 9 месяцев назад

      I ended doing a trial for Spravato (esketamine). It didn't do anything for me...

  • @garysimone4977
    @garysimone4977 2 года назад

    This 50% successful I understand

  • @musluvmusic
    @musluvmusic Год назад

    Can you use some of that money and let me get the rest of the treatments I need and some esketamine for use at home. It really helps my migraines and all my surgery places and past wounds along with the ptsd and depression

    • @musluvmusic
      @musluvmusic Год назад

      @Douglas Wendy they are over priced greedy scammers

    • @musluvmusic
      @musluvmusic Год назад

      @Douglas Wendy they are all scammers

    • @musluvmusic
      @musluvmusic Год назад

      @Douglas Wendy All scammers

  • @fallon7616
    @fallon7616 2 года назад +3

    I agree ! I am suicidal! My Dr suggests Ketamine & my husband is unemployed and I am on Medicare. Wow. Talk about desperate

    • @healcptsd6467
      @healcptsd6467 2 года назад +1

      Move to Sweden Here you can get it for free 😊

    • @TheRusschannel
      @TheRusschannel 2 года назад +1

      Ketamine is GENERIC AND CHEAP, dont let them screw you!!!! COMPOUND IT guys !!! Use your brains..

    • @healcptsd6467
      @healcptsd6467 2 года назад

      @@TheRusschannel It is but in the US they still charge 300 per treatment....

    • @TheRusschannel
      @TheRusschannel 2 года назад

      @@healcptsd6467 Get an RX from your dr, Buy the medicine from a compound pharmacy for under $100 which gives you 120 doses at 25mg each... That will last you a month or 2... hardly $300 dear... Be smart, dont feed the greedy cash cows in the USA...

    • @Kthb80
      @Kthb80 2 года назад

      @@TheRusschannel 25 mg though that’s a tiny amount, I’m prescribed 200 mg three times a week. It costs me about $60 a month. The infusions were very expensive.

  • @TheRusschannel
    @TheRusschannel 2 года назад

    Ketamine is GENERIC AND CHEAP, dont let them screw you!!!! COMPOUND IT guys !!! Use your brains..

    • @SunscreenAndVitamins
      @SunscreenAndVitamins 2 года назад

      wtf does that even mean? get it compounded how?

    • @TheRusschannel
      @TheRusschannel 2 года назад

      @@SunscreenAndVitamins compound pharmacies make ketamine tabs for about $1 a dose

  • @mikesmith1702
    @mikesmith1702 2 года назад

    good job getting a patent on a generic drug the costs the same as bottled water to sell it for a10K mark up.

  • @guitarexpert2245
    @guitarexpert2245 2 года назад +2

    Does he mention it costs $400 per session and only lasts a few days? This treatment is for the rich only. It doesnt last more than a few days. What is the point of Ketamine? its just makes doctors money.

    • @TheRusschannel
      @TheRusschannel 2 года назад +2

      Ketamine is GENERIC AND CHEAP, dont let them screw you!!!! COMPOUND IT guys !!! Use your brains..

    • @guitarexpert2245
      @guitarexpert2245 2 года назад

      @@TheRusschannel I"ve done that already cost me $20

    • @kihntagious
      @kihntagious 2 года назад

      How did you do that and is it working?

    • @garysimone4977
      @garysimone4977 2 года назад

      @@kihntagious 20 bucks. I don't believe it

    • @garysimone4977
      @garysimone4977 2 года назад

      @@guitarexpert2245 20...no way

  • @Miss_Millie_
    @Miss_Millie_ 3 года назад +4

    It's addictive & you develop a tolerance quickly - the dosage is constantly needing to be titrated up - he fails to mention that. Oh, & the drug is super expensive + the regular shrink appointments. You'll start depressed & end up a broke addict!

    • @anthax908
      @anthax908 3 года назад

      The drug is quite cheap, but buying it from them is.

    • @Kthb80
      @Kthb80 3 года назад +2

      I’ve been on the lozenges for only two weeks, in that time I already need to take twice as much as I did two weeks ago for the same affect.

    • @guitarexpert2245
      @guitarexpert2245 2 года назад +2

      All these doctors are the same. It makes them money. However, at $400 a treatment that lasts just a few days. Most people cannot afford this. Does he meniton this? NO. Why, because hes a doctor and its bad for business.

    • @andrzejstrzelba9026
      @andrzejstrzelba9026 2 года назад +2

      @@guitarexpert2245 Fortunately, in my country it is for free. Poland, Gdańsk.

    • @healcptsd6467
      @healcptsd6467 2 года назад +2

      @@andrzejstrzelba9026 In Sweden as well 😊