Current Research on Keto as a Treatment for Mental Illness | with Dr. Bret Scher
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- Опубликовано: 5 мар 2024
- We got to sit down with Dr. Bret Scher again to discuss what the current landscape of research around using the ketogenic diet in the treatment of psychiatric disorders looks like. Dr. Scher is a metabolic health specialist and is also the Director of Metabolic Mind, a nonprofit transforming the study and treatment of mental disorders by exploring the connection between metabolism and brain health. He is also the host of Metabolic Mind's RUclips channel ( @metabolicmind ) where you can learn even more about metabolic health.
Thank you so much Dr. Scher for joining us!
ONGOING RESEARCH TO CHECK OUT:
Summary of completed clinical trials and active clinical trials examining a ketogenic diet in serious mental illness:
www.metabolicmind.org/research
Clinical trials underway examining the impact of the ketogenic diet on various psychiatric disorders:
clinicaltrials.gov/search?con...
Stanford Medicine Metabolic Psychiatry website:
www.metabolicpsychiatry.com/r...
New clinical trial looking at bipolar and keto:
www.psychiatry.pitt.edu/pitt-...
Some of the current evidence that has led to exploring clinical trials:
pubmed.ncbi.nlm.nih.gov/37066...
www.frontiersin.org/journals/...
MEDICAL KETO RESOURCES
You can learn more about medical keto for mental illnesses on the Metabolic Mind RUclips channel (@metabolicmind) and on their website www.metabolicmind.org/
You can also learn more about metabolic health and mental illness from the book 'Brain Energy' by Dr. Christopher Palmer - brainenergy.com/
You can find more about my keto coach Nicole Laurent and her work on her website:
www.mentalhealthketo.com/
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www.laurenkennedywest.com/
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#schizophrenia #schizoaffective #schizoaffectivedisorder #mentalhealth #mentalillness #metabolichealth #keto #metabolichealth #research #clinicaltrials
ONGOING RESEARCH TO CHECK OUT:
Summary of completed clinical trials and active clinical trials examining a ketogenic diet in serious mental illness:
www.metabolicmind.org/research
Clinical trials underway examining the impact of the ketogenic diet on various psychiatric disorders:
clinicaltrials.gov/search?cond=Psychiatric%20Disorder&intr=ketogenic%20diet
Stanford Medicine Metabolic Psychiatry website:
www.metabolicpsychiatry.com/research
New clinical trial looking at bipolar and keto:
www.psychiatry.pitt.edu/pitt-psychiatry-awarded-6m-baszucki-brain-research-fund-grant-study-therapeutic-effect-ketogenic
Some of the current evidence that has led to exploring clinical trials:
pubmed.ncbi.nlm.nih.gov/37066662/
www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1358578/full
Keep going.
@@GgeezuzzTake your meds and get offline.
To anyone out there struggling with medications side effects: do not be afraid to advocate for yourself and explore different options. As a scientist, I agree that there’s a spectrum of evidence one can draw from beyond randomized clinical trials. I myself asked my psychiatrist to try a different medication for my OCD (one with much lower levels of evidence) because of intolerable side effects. It worked and continues to work great.
thanks!
I agree that practicing self-advocacy is a good idea and I’m glad you found a med that works for you.
With that said, it can be somewhat harder for people with psychotic illnesses to be heard and believed by mental health practitioners, even when presenting a tight, well-reasoned argument.
That’s not to say it’s not possible to initiate change, but it’s an additional barrier when you’ve been labeled an unreliable narrator by the medical system.
12 weeks is not a long enough study for bipolar disorder.
@@W1gglewaffle I was talking about the 12 week study that the doctor mentioned. Not about Lauren. Though I agree that 12 weeks is not long enough either way.
It's not enough to prove it's a long term "cure" but it's enough to see if patients react in a positive way. But there are individuals who've been followed for as long as 3-5 years and were all doing great and in the 5 year case I read about the women stopped taking her prescription meds after 3 years, and 2 years later she told her doctors she was basically "cured" and didn't need check in with them any longer.
From what I've read the keto diet changes the gut microbiology. It basically feeds the good gut bugs and starves or kills off the bad ones. There are like millions of kinds of gut bugs, but one study I read said they found at least 5-6 specific bugs that all of those they tested who suffered with psychosis had in common and the keto diet got rid of those.
I think the toughest part of this treatment is getting patients to start and stick with the diet. That takes some effort on their part and sugar probably promotes the bad gut bugs, and that can be addictive.
Truth is, what we don't know about both psychosis and gut bugs far exceeds what we do know. But we now do know there is a connection between our gut bugs and our brain and psychosis. And that's a pretty huge leap ahead from where we were even just 5 years ago and the keto diet has proved that.
I'm doing the Keto diet and exercise for my Schizoaffective disorder. It has helped tremendously. The only issue I'm still having is my sleep. It's all over the place. I'm up late, have broken sleep and tend to have a hard time getting up in the morning hours. Other than that, I'm improving. Really grateful for doctors like Dr. Scher who are studying this treatment.
How long have you been on keto?
@xxxxzzzzz5943 Since Lauren started, about 2 1/2 months.
I’m starting keto too for my schizophrenia. I’ve noticed improvements too, but like you I feel it still takes me a while to wake up in the morning. Is it medication related? Once I wake up, I feel good the rest of the day.
@caitlinhoey841 I have always had sleep issues, even when not on meds. But they probably don't help. I was hoping that Keto would help with my sleep issues too.
Hi!! Could you share how you are facing the side effects of the medicine like being super hungry with the keto diet? That is one of the biggest issues I have with my sza partner. Do you also do intermittent fasting? I'm happy to hear you are much better.
Would be great to have a residence clinic that had all these practices in place where one could stay.
Especially for those mentally ill who are on the streets desperately ill or those who are not able to manage this therapy on their own.
And it would seem that would provide amazing data for research because it could be an in-house research project. All details followed carefully by medical professionals using this therapy.
I agree!
A doctor in France was able to do just that with 22 or 24 of his long-time, treatment resistant patients. High percentage of really nice improvement, including reducing dosage of meds and eliminating others. If you can’t handle keto right now, try going all carnivore. BBBE - Beef, Bacon, Butter and Eggs.
Hi Lauren, I use the Keto diet along with intermittent fasting (18/6) to control my epilepsy and I am 2 years seizure free. As I am still on meds I can't say for certain it's the diet, but at the same time, I can't see it being a coincidence that I am 2 years seizure free. I'm no doctor just my 2 cents. I hope you're good.
Thank you Lauren for staying on top of this research. Very complex subject, even if you exclude the general rule that humans are not particularly rational.
I really appreciate you delving deeply into this. My brain seems to feel better to me with protein and saturated fats, and, being elderly, I have to monitor my heart health numbers and artery/plaque conditions. Thank you for doing the work, and also for doing such a high quality of presentatation of it.
I would love to know more about markers for metabolic dysfunction that might let you know if keto will work for you or not and why. Thanks for the video! The more research the merrier.
These are the criteria for metabolic syndrome. Get these in order and you will be well on your way there. Keto is quite good for all of them:
Abdominal obesity. This means having a waist circumference of more than 35 inches for women and more than 40 inches for men. An increased waist circumference is the form of obesity most strongly tied to metabolic syndrome.
High blood pressure of 130/80 mm Hg (millimeters of mercury) or higher. Normal blood pressure is defined as less than 120 mm Hg for systolic pressure (the top number), and less than 80 mm Hg for diastolic pressure (the bottom number). High blood pressure is strongly tied to obesity. It is often found in people with insulin resistance.
Impaired fasting blood glucose. This means a level equal to or greater than 100 mg/dL
High triglyceride levels of more than 150 mg/dL. Triglycerides are a type of fat in the blood.
Low HDL (good) cholesterol. Less than 40 mg/dL for men and less than 50 mg/dL for women is considered low.
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Over 93% of Americans have at least one of the criteria for metabolic syndrome
Good question!. Here's a video we did about testing for insulin resistance. ruclips.net/video/W-lmYCqjtmg/видео.html Although one caveat is that many experts will say that ketosis can help some people even without obvious metabolic dysfunction. It's just that it may help whose with metabolic dysfunction even more. Hope that helps!
thank you for the detailed response!@@CashMoneyMoore
Great, thank you so much! I'm checking it out now!@@metabolicmind
When you say it may help people with metabolic dysfunction more than those without it, how so? Would it clear up more of their mental condition symptoms?@@metabolicmind
Thanks for this. The sort of epistemological clarification was particularly interesting to me.
Your eyes look absolutely bluetiful today! 💙
Wow people really are struggling with this keto trial I can’t believe how much the comments have turned negative or skeptical and how many less comments there are from people who have schizophrenia spectrum illnesses saying they feel supported by your videos. I hope people with schizophrenia that so valued this channel aren’t feeling alienated by the content. I feel like that but I thought it was just me it feels like Lauren has left us behind and gone off on a very unique and unreachable treatment method abd lifestyle for many of us right now in the midst of psychotic illness and it makes sense but it also sucks
Whyv s it unreachable? I don't think she's leaving people behind so much as trying our a non medical pathway - which is working for her.
It's always good to see you, lauren! Please keep posting often.
Glad to hear your doing well lauren.
Thank you for sharing information like this! Is very interesting to research and learn more about non pharmacological treatments for neuropsychiatric disorders.
The Keto diet causes me concern with my cholesterol. I already have high cholesterol but don’t take statins.
Would it be possible for you to talk to someone who doesn't have ties to keto to explore the possible risks and give a more balanced perspective? Whilst the experts you are speaking to are certainly well qualified, they are also biased as they have skin in the game. The studies you linked look promising, but the evidence is not strong enough yet to safely recommend this to viewers. I just worry about dogmatism in the keto-sphere. Thank you.
Agree they are all keto practitioners someone who isn’t studying or working for a ketogenic therapy clinic would be helpful and more balanced lots of doctors use the ketogenic diet for epilepsy and type 2 diabetes but not for everything so any doctor particularly a paediatrician as they use it more often just not for unproven “currently not yet approved reasons” those doctors aren’t anti keto they use it it’s well known not specialised but they also aren’t basing their whole career on it being a possible miracle cure either
According to a book I’m reading titled The Wisdom of Mental Illness, you are going through initiation of becoming a shaman. The book talks a lot about something called shamanic sickness and how that propels people like you onward towards enlightenment in health and helping to heal others through their experiences.
Even well funded drug trials take decades. KarXT, a potiential wonder medicine for Schitzophrenia and related disorders, has taken almost 20 years between concept and availability. Perhaps it will be available in 2025 or 2026.
What's good for the body is good for the mind and vice versa. I have been focusing on total body health more for a while now and it's had a great effect on my mental health as well.
Is there any chance this might work for treating PMDD?
Cool I'm on day two now. Not sure if i'm doing it right but I feel like I did a good job. My partner wasn't so supportive but he will cope. I have Psychosis NOS, and i take Abilify. My hope is to go off meds completely, which is possible.
Very interesting! Is there any information about this on the Internet or studies?
Lauren, what exact meds do you take?
I hope you see this. You are so beautiful, inside and out. Great work dearie!
Hi
How do I get onto this for my daughter ?
Any info or resources ?
I’d appreciate
Live in US’
Thank you
Talented interviewer
I happened to see two new books at the library that directly talk about diet as a treatment for mental illness. They are "Change Your Diet, Change Your Mind" by Georgia Ede, MD who is a metabolic psychiatrist and developed the first and only medically accredited Ketogenic Diets for Mental Health Clinician Training Program (seems like you would want to interview her), and "Calm Your Mind With Food" by Uma Naidoo which is more about anxiety and the gut-brain connection. I'm not sure if it talks much about keto.
In Studies include all social economic groups
so im 16 and living in wv and because of the healthcare problems in wv it was hard for me to get help for my schizoaffective disorder mainly because of my early age. and so ive been looking for new ways to improve my mental and physical wellbeing. what would you recommend for my age range regarding a ketogenic diet?
ps i am not self diagnosed/i do have medication, i just want to try something less invasive.
maybe explore more proteins, less white flour based foods at first & see how you feel after a week or two.
But it is true, i think most of my illness comes from the meds (for epilepsy) i still scare to let completly my medicaments because i really can d!e😅 because my seizures are unconsious and very short but strong and that deteriores my brain everytime i have a seizure. I only have 3 seizures from adult time, with what i got diagnosed and my brain is very bad😅. One of the 3 seizures i had came from trying to stop taking my medication. And with a strong medication like for epilepsy and i am sure for schizo too, the others medications don't help at all, like CBD, even clonazepam do nothing to my sleep😅 only ezopiclone but this drug is very strong and deteriorate the brain also (from experience). I think the worse symptoms you could have in general, comes from lack of sleep. And i mean you for all of us😅. Sicnce 4 years i can not sleep and i have a lot of health problems now, maybe all started with meds but it got stronger with the sleepless nights.
Thank you for providing this information!
2x 0.5g vitamin C daily significantly improved insulin resistance in type 2. It didn't change a1c, I guess that still depends on carb intake. But on a keto diet, you don't have that problem so vit c might do as well on insulin resistance as metformin.
EDIT: well scurvy in guinea pigs causes low glucose tolerance and very low insulin secretion, so maybe quite a bit of type 2 is vitamin C deficiency?
That's interesting, I believe Dr. Richard Johnson has spoken about this that vit c blocks fructose metabolism. Vit c and water around carb consumption could be a good idea. Another interesting treatment is Allulose. Allulose blocks the absorption of glucose so if you take it right before a sweet potato or something your glucose will be much lower than if you hadn't taken it. He's an expert on insulin resistance and recommends the keto diet as a treatment as well
I'd think sticking strictly to nationally recommended food guides for healthy eating would be just as beneficial.
You will lose fat, but the thing to watch out for is losing muscle. I lost 50 pounds in a few months before I realized a lot was muscle. I wish you the best of luck.
I wish there was a way to get more research funding into nutritional and other therapies besides pharmaceutical ones. Wouldn't insurance companies benefit from prescribing patients exercise and better nutrition than paying loads of money on prescribing psychiatric drugs? Why don't they fund these types of studies?
What if you have mental illness and diabetes type 2? I worry I'll get ketoacidosis if I try this diet.
The other issue is who would ever be covered by insurance to supervise me if I did try this keto diet?
keto is great treatment for type 2 diabetes. American diabetic association says keto/low carb diets are legitimate tools to treat T2D
Here's some research: did you know that going off or reducing your medication is known to cause your medication to not work at all. Is this Dr. an expert on Psychosis-related illnesses?
Laurea!!!! Thank You for sharing your experience and Metabolic Mind! SUGAR is a poison for some of us with mental issues… from Cutting out sugar all the way to Carnivore almost EVERYONE improves in some way… even if it helps with antipsychotic medication weight gain… some may binge on fruit and are reversed doing a high fat keto diet. Thank you for sharing!!!!
My comment may have come out wrong…. What I mean is the spectrum from cutting out added sugar to paleo low carb medical keto and carnivore… even if all symptoms are not completely gone it still helps when you get rid of the sugar… unfortunately the psych ward feeds processed fruit cups and sugary milk. I don’t see how any of that is controversial? Hope that clears that up ❤
I am not on full keto diet, but on part, and thanks to you, i have tried it and i feel a lot better. More I think of my psychosis, the more I think I was possessed by demons. Honestly, I cant find different explanation.
If you are possessed by demons then an exorcism would work better than psychiatric medicines. But psychiatric medicines work better. That is why most churches won't do exorcisms any more.
Don't know why I can't reply on your comments which you reply me on last video
God bless you always and I will pray for you. I did not miss the medicine even once in 15 months. My doctor did not tell me about this mental illness in the beginning. So I searched medicine and saw that I have schizophrenia.Many Md psychiat tell schizophrenia treatment is 2-3 years??? I started from 9 mg and Now I'm on 5mg,I was also take 4mg but only 10 days which makes me feel much better. after 10 days I shifted on 5 mg which doctor prescribed
The association between metabolic dysfunction and mental health is really strong. There was a study of children at age 10 who if they were insulin resistant were 5 times more likely to have been diagnosed with or at high risk for Schizophrenia by age 18.
We should not be allowing our kids to be metabolically unhealthy we are putting them and our selves at risk!
I read a study somewhere that omega 3 can prevent or migiate psychosis is this true or a myth.
There’s also an association between insulin resistance and childhood trauma. I understand your line of thinking and am open to the idea of metabolic intervention, but I also don’t want us to be locating the entirety of the problem within the biology of the child when we should also be looking to relational stressors in their environments.
Of course, but there are metabolic treatments that can be effective even if the damage is coming from something like trauma. Just because diet can treat metabolic damage doesn't mean that the previous diet caused it. Same for exercise, you might be metabolically and exercise can correct that, but it wasn't necessarily the case that not exercising is what made you sick. If that makes sense@@80islandia
This is fascinating! Thank you!
Lambert demonstrated the effectiveness of valproic acid in France in 1968, this study that lead to its widespread use in France to treat bipolar. What has been forgotten and lost to history is that Lambert's patients had "epileptic insanity".
For some reason almost all mood stabilizers are antiepileptics.
@@Catlily5 Yes, although lithium is thought to be slightly proconvulsant depending on the brain region.
But yes, for the most part there is a clear link.People don't seem to be able to see the significance of the connection. In the 1990s the second messenger effects of anticonvulsants were all the rage and anything with the slightest effect on epilepsy was tried out. Now it's true that most of these agents didn't work but many probably did do a little bit of good, just not enough to pass RCT.
The theory is sound enough, although it's not nearly enough evidence to say something works. It is however enough to bring something like keto well and truly out of the fad diet realm. If we took all these other anticonvulsants seriously, why shouldn't we take keto seriously?
@@replaceablehead It will be interesting to see what happens with Keto.
It's not new, Kraepelin wrote about it: "autointoxication".
I loved the video!! It is so great to here that more of these studies are going on, and that most of them are having such positive outcomes. I know I have only been following your channel for a short time. and that I don't normally comment. but I did want to point out a correlation that I was seeing in Your Blinking during the video. You only seem to blink a lot when you are Listening. or auditorily processing information. When you are talking, or verbally processing information. your blinking REALLY slows down. You know the old trick where you sit in a chair. pat your head, rub your tummy, and make a circle with your foot. and one of them normally goes the wrong way. But if you are listening to music, it activates other connections in the neurons and most people can do it then. Well I am just wondering if it would work the same. that if you had music going in the background. or headphones on quietly. WHILE listening to someone else talk. if you would blink less. I did this years ago. As my father would always call me a Sissy for blinking all the time. before I was diagnosed. and it seemed to help. Just a thought. Thank you for all of your hard work. and videos. and for being our Ginny Pig. HAHA in this process. I am looking at changing to the Keto diet myself. and admittedly, selfishly, have been waiting to see how you are doing with it. but now i think I am defiantly going to try it. My brother went to school for sports medicine, and dietary health. so I will defiantly have some support. Thanks, again. Tom in ND.
please show keetogenic diet food.
I always say to my son that it really seems to mainly be a sleep problem. Like he's dreaming when he's awake.
Sleep is definitely a part of it.
@@Catlily5I got him a Smartwatch and he's been sleeping a lot better than I thought he was.
To much to soon I find is a factor in the process of the decline of my mental symptoms do you think the diet can help
Thanks!
The worst is being given antipsychotics when you don't have schizophrenia. This happened to me and destroyed my mind and my body.
Hope you're also taking your physical health into consideration while on the keto diet. Theres lots of information on the downfalls of this diet
Did you tried magnesium chloride? Its good for epilepsy and a lot of things more❤
Talk about your medications.
Well the drugs companies would not exist if a a diet solved mental health.
From what I hear this diet is hard to stick with so they probably still would have business.
The drug companies would be a lot poorer if people stopped being lazy and fat. Literally scienced.
Thank you. Of course what you feed your body will affect it.
🎉🎉🎉🕸️🕸️
I have schizophrenia
KarXT
Hi, just wondering if you have ever tried parasite cleansing and what were the results if so? Or have you heard of it or thought about doing it? My husband has schizophrenia and we are interested in doing this.
What scientific evidence supports this?
Have you researched MTHFR?!?!? U can add supplements if u have this and 10-20% of Americans have it
Please read this I turned my TV on to go onto RUclips and your 9 months old video popped up when you were at a psych ward Hospital and I just don't understand how people say that you are sick you are not sick you are under attack and I don't know what you believe but I just feel in my heart like I have to say this I have been dealing with demonic presence since I was a child I have studied myself for 29 years and I have everything is that a doctor can diagnose the truth is that schizophrenia sadly is looked at the person and not spiritual it breaks my heart for you because I don't think you understand that life is so much more than what doctors know or could ever understand I still to this day deal with the worst possible attacks I have had a horrible horrible month and I hope that I'm not offending you in any way shape or form I just want you to know that I don't know anything about you I just right now came across that video I looked you up on my phone I don't I know if anybody has told you that this is the devil attacking you but it's very true demons attack in many ways shapes and forms and I'm so sorry you're going through this I just want you to know that you're not alone I don't know if you believe in God I'm barely trying to figure everything out myself but something is telling me to tell you this it was put on my heart to write you on your newest video right now I'm going through a lot and I cannot watch any updates but there is so much more to schizophrenia than people could ever truly understand I hope you are doing well I'm sorry if this all seems super blunt I just don't have any life in me to explain things in great detail at the moment because I am being attacked myself but I will keep watching as soon as I can oh and by the way in the video you said you were getting two doses of Haldol a day and I remember when I got that and I am so severely allergic to it it's mind-blowing
Im really concerned with the risk of diabetes with keto. I saw my BG go up the entire 2 months I was doing keto. And elevated glucose increases glycation end products. Its definitely not the most healthy diet and has risks for many. But I understand the use for specific conditions.
Are you sure you were doing keto? Blood glucose in all the RCTs are very stable and drop to low healthy levels. Even the American Diabetes association now recognizes low carb and keto diets as an effective way to treat diabetes
There are literally hundreds of thousands of people on ketogenic diet to specifically lower their blood sugar (myself and my wife included). I'm not sure under what mechanism your blood glucose would rise when eating so few carbs.
@@reinerschafer1708how long have you been on it?
@@TammiJayneBodenhamComing up to 5 years now.
:)
Can you please make a video on lsd and schizophrenia it would mean the world to me. Ever since I took that drug once I have had schizophrenia and I just want some answers. Thank you!
It’s like enough talking about it of course it works! There just need to be more effective treatments in psychiatry targeting mitochondria. Psychiatry is so behind in doing much of anything. Jogging is great for negative symptoms but if you want to go out and have a life, a career it takes up time And energy on the patients behalf. I mean, develop more effective treatments! Move the needle for god sakes
i know right. psychiatry has become so obsessed with "do no harm" (which they absolutely did do historically) that they've basically paralyzed themselves and their patients
@@davethepantsI don't think so. They put people on strong medicines every day.
Dear Lauren Please Make Sure Your Experience Is Personal Not Health Care Provider Even With Doctor's Speaking It Could Cause Some To Stop There Meds Peace Warmly Chris
If anyone listens to her videos, she has not stopped her meds and doesn’t condone that at all.
Better off on the Mediterranean diet for longevity
Association does not equal causation, and if you experience symptom relief with keto but not Mediterranean which one are you going to pick
@@CashMoneyMoore Mediterranean every time- Keto will put you in an early grave if you to keep it up 🪦
What if it gives someone a life they feel is actually worth living?
Another keto video?
Why do you constantly blink your eyes while listening to someone talk?
Because she is having tarditive dyskinesia 😊 this comes from antipsychotics. i really hate this channel since december 2023 - it is all about the keto diet, which is complete nonsense.
For me personally, my body runs on carbohydrates - I have done a gene test. I tried keto/low carb with 0 effect. I just had sleepless nights. I also tried to eat high protein, also with 0 effect.
Guess what, the dna gene test suggests, that I personally need:
- 54 % carbohydrates
- 28 % fat
- 18 % protein
I am gonna stick with that. Beware that the carbohydrates have to be complex and not like sugar, white bread etc.
If you don‘t want joy in your life, start with the keto diet. 🎉
Your brain had been destroyed by those drugs
Gut Check, by Dr. Steven Gundry...run circles this presentation...
Gundry is an opportunist.
Stop to promoting psych meds
why this disorder cause can someone explain me plsss?
Partly genetics, partly environment. But they don't know the exact cause.
Has the carnivore diet been tried? My son refuses to take his meds. He was taking in too much sugar. Now that that has been greatly reduced, he's finally sleeping better and lost 20 pounds the first month.