Friedel-Crafts Alkylation

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  • Опубликовано: 1 янв 2025

Комментарии • 164

  • @roxx_ve
    @roxx_ve 6 лет назад +44

    Thank you so much! I'm a second semester organic chemistry student, and I've watched several of your videos to help me with homework and tests.

  • @Iklilledurhamster49
    @Iklilledurhamster49 8 лет назад +522

    all hail chemistry jesus

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 лет назад +325

      thank you, my son.

    • @hamedhosseini4938
      @hamedhosseini4938 8 лет назад +10

      HAAHAH so true :DDDD

    • @andriansmith3142
      @andriansmith3142 7 лет назад +9

      A miracle worker indeed. You saved 3 organic courses of mine :P (pun intended). You show the one true path to graduation :P

    • @elafm2344
      @elafm2344 7 лет назад +1

      F

    • @cpn6464
      @cpn6464 4 года назад +12

      Makes more sense to worship a worldly genius than a mythical sky god.

  • @TiedAlpaca00624
    @TiedAlpaca00624 2 месяца назад +4

    And thus, a legend was born. Destined to get yelled at by James Tour, take on many challenges such as flat earth, electric universe, young earth creationism, and having to repeat basic scientific observations 50 times only to get demonized.

  • @unslashed
    @unslashed 8 лет назад +12

    You are the real hero. I'm so glad that I discovered your channel before it was too late. (have the final on 16th of december and all the slides are in French, coz they just added organic chemistry to the program, polymer science master Strasbourg-Freiburg, and the only professor with terrible English teaches organic chemistry) you are my savior

  • @glendamacco4764
    @glendamacco4764 7 лет назад +77

    currently pulling an all nighter for an o chem test tmrw at 8 am. just started watching your channel, you're the bomb!

  • @Umbriel92
    @Umbriel92 Год назад +12

    A legend was born

  • @moribnd
    @moribnd 7 лет назад +12

    Thanks, Dave. Short and to-the-point.

  • @twinnerNet
    @twinnerNet Месяц назад

    It's neat to see your evolution over time. The science heavy teacher stuff is great. The no nonsense frank debunker stuff is great too. I look forward to another nine years and more of your lessons.

  • @shakatapuramshrividya1148
    @shakatapuramshrividya1148 10 лет назад +12

    woah,man,this is good. I told a coupla my friends already!

  • @massrdmdoer7348
    @massrdmdoer7348 11 месяцев назад

    man I love chemistry, my school teacher told me not skip ahead with material as to not overwhelm myself, but I simply enjoy the subject

  • @IsmailAhmed_Ishydadon
    @IsmailAhmed_Ishydadon 7 лет назад +16

    Not all heroes wear a cape. This is showing up on my exam next week and you just saved my ass. 👍 👍 👍

    • @melancall5960
      @melancall5960 3 года назад +1

      Pass the exam?

    • @IsmailAhmed_Ishydadon
      @IsmailAhmed_Ishydadon 3 года назад +3

      @@melancall5960 damn this was 4 years ago. I did pass and graduated almost 1.5 years ago 😂

    • @user-eh9lc4wp2c
      @user-eh9lc4wp2c Год назад +1

      ​@@IsmailAhmed_IshydadonHi pal, what are you pursuing now? I'm just curious

  • @brandonswritingservices7787
    @brandonswritingservices7787 6 месяцев назад +19

    Who is here in 2024?

  • @Kiky_MedPhysicist
    @Kiky_MedPhysicist 4 месяца назад +2

    So, this is how the legend was born 🫡

  • @AlecuBeldiman68420
    @AlecuBeldiman68420 2 года назад +7

    And so, a legend was born

  • @Riyuihein
    @Riyuihein 10 месяцев назад +2

    I ma here before my exams 😭 thank you so much sir

  • @Daniel-nu8uk
    @Daniel-nu8uk 10 лет назад +7

    Perfectly explained.Where have you been bro for all these years??

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  10 лет назад +33

      Teaching in the flesh! But now it's time to share the wealth with the people. Please spread the word!

    • @GamingForeverEpic
      @GamingForeverEpic Год назад +2

      @@ProfessorDaveExplains your old

    • @RAJ_GADHAVI
      @RAJ_GADHAVI Год назад +2

      Bro you are the first commenter on this channel 😂

    • @TylerTMG
      @TylerTMG Год назад +1

      @@RAJ_GADHAVI no he's not it's way later
      Just because it's the first comment on the first video doesn't mean it's first

    • @blagoevski336
      @blagoevski336 11 месяцев назад +1

      ​@@TylerTMGnigga what

  • @Nikkunj
    @Nikkunj Год назад +2

    thank you very much sir,I am a class 11 student and this video really helped me

  • @LexoG33
    @LexoG33 8 лет назад +2

    That's a cool tattoo Professor Dave. Now I know how a parsec is defined!

  • @adeshvinod4748
    @adeshvinod4748 9 лет назад +9

    You sir are a savior!
    Extremely well done, Dont stop making more☺

  • @martinweiss5355
    @martinweiss5355 7 лет назад +1

    Realy helpful thx. I´m from germany and there was no problem understanding you. So well done !

    • @martinweiss5355
      @martinweiss5355 7 лет назад

      Anyone an idea about the +M - effect ? Its relevant for my Test tomorrow.

  • @sanjoosona
    @sanjoosona 4 года назад +7

    Sir now u have 1million subs
    🔥🔥🔥👍👍🙏
    Keep it down👍👍👍

    • @Garrettmoron
      @Garrettmoron 9 месяцев назад

      Yeah, because he can’t do anything apart from making yt vids.

  • @samlal3618
    @samlal3618 3 года назад

    Thank you so much you have NO idea how much your saving me right now

  • @therevprogamers
    @therevprogamers 6 лет назад +2

    Awesome explanation , thanks for it

  • @dubola5777
    @dubola5777 6 лет назад

    Short and to the point, i like it! Thank you!

  • @lovedavis7376
    @lovedavis7376 8 месяцев назад +2

    All hail chemistry Muhammad. Just discovered the channel.Im learning so many new things . Thank you for taking the time out to post

    • @knoobiez
      @knoobiez 7 месяцев назад

      Ur going to hell

  • @karenopt
    @karenopt 4 года назад +1

    Also, when is rearrangement needed for Electrophilic Aromatic Substitution?

  • @pleaseunsubscribeme8533
    @pleaseunsubscribeme8533 4 года назад +2

    Y amine doent undergo fridel craft alkylation? Is there any other compounds other than amine and phenol?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 года назад +5

      the group with a lone pair will interact with the lewis acid catalyst before the alkyl chloride has a chance to

  • @stickanimation9888
    @stickanimation9888 25 дней назад +4

    You are coming from the last video

  • @gehtdinixan1935
    @gehtdinixan1935 7 месяцев назад

    where does the H comes from at 2:45? that is also attached to the ring next to the alkyl fragment

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 месяцев назад +8

      every carbon in a benzene ring has one hydrogen, they are just implied unless needed for the mechanism

    • @gehtdinixan1935
      @gehtdinixan1935 7 месяцев назад

      Stupid me ugh, thanks!

  • @karenopt
    @karenopt 4 года назад

    Why do we restore aromaticity? What is the significance?

  • @ramashamyleh9431
    @ramashamyleh9431 5 лет назад +1

    Thanx prof.
    All respect for u

  • @mireamema162
    @mireamema162 5 лет назад +2

    Yor are reallly incredible and a lifesaver(THANK YOU) Although I do have a question: Does a multiple substitution happen here?

  • @rassimsimou1594
    @rassimsimou1594 10 месяцев назад +2

    Good

  • @medifectious
    @medifectious 9 лет назад

    You see how you said chlorine has 6 valence electrons and aluminium has 4 valence electrons should the chlorine not be negative because it has more electrons. If not why is that? It's at 1:15

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 лет назад

      Random Help In the catalytic complex, chlorine will have a formal positive charge because it's showing 6 electrons in the lewis dot structure, one per bond and two lone pairs, compared to its typical valence of 7. One fewer electrons means a positive charge. Aluminum shows 4 electrons, one per bond. Its typical valence is 3 so this has a formal negative charge.

    • @medifectious
      @medifectious 9 лет назад

      You mean one lone pair right or there would be 8 valence electrons 0-0

  • @a_nuraqilahbintikhairul1353
    @a_nuraqilahbintikhairul1353 4 года назад

    thank you professor Dave

  • @jeff-freehoke8012
    @jeff-freehoke8012 6 лет назад +7

    There was no music. wtf

  • @saintofchelseathomascarlyl5713
    @saintofchelseathomascarlyl5713 6 лет назад

    i love the new intro

  • @exoinvadedmymind1006
    @exoinvadedmymind1006 5 лет назад

    What's the limitations I don't get them do u have a video of them 😭😭 polyalkylation and carbocation rearrangement

  • @kuntalkoley3107
    @kuntalkoley3107 6 лет назад

    Sir, what you are discussing is Friedel craft alkylation. Have you made any vedio on acylation?

  • @abd2002
    @abd2002 3 года назад +1

    First video? 😮

  • @fatimaalkwndy9673
    @fatimaalkwndy9673 Год назад +2

    but what is the difference between this and halogenation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  Год назад +4

      this is alkylation

    • @fatimaalkwndy9673
      @fatimaalkwndy9673 Год назад

      like if I had a question on the test that says to explain the mechanism of the reaction with the same catalytic complex that we used in the halogenation how would I know its not Friedle reaction? I know my question is kinda stupid but I have a test tomorrow and I am soooo nervous

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  Год назад +4

      @@fatimaalkwndy9673 alkylation will require an alkyl chloride, so R-Cl + AlCl3 you know it is alkylation

    • @fatimaalkwndy9673
      @fatimaalkwndy9673 Год назад +3

      thank u sssso much sir you're life savior

  • @anshumaanshukla7443
    @anshumaanshukla7443 5 лет назад +1

    sir, do u have any videos that might help me with understanding the +m effect?

  • @MiddleTN_Cubaris
    @MiddleTN_Cubaris 6 лет назад

    You are clutch, my good sir

  • @hamedhosseini4938
    @hamedhosseini4938 8 лет назад

    Professor is a big lad.

  • @krishnapanigrahi2235
    @krishnapanigrahi2235 7 лет назад +1

    thank you so much

  • @rygalindo
    @rygalindo 7 лет назад

    If the benzene ring already has a substit. group on the ring that does not prevent the reaction, I'v been told that it adds to the meta position, is this correct?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад +1

      the regioselectivity of an electrophilic aromatic substitution reaction on a monosubstituted ring depends on the identity of the substituent, check out my clip on o/m/p directors!

  • @Aadi129
    @Aadi129 Год назад

    What are hybrid orbitals of phenol amine tetra di phosphate ????

  • @Shugenjya
    @Shugenjya 8 лет назад

    Thanks for the explanation, But i have a question. Why does the chloroalkene wants do bond with the AlCl3?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 лет назад +2

      just a Lewis acid-base reaction! chlorine's got lone pairs, aluminum is electron-deficient.

    • @ashutoshdash5965
      @ashutoshdash5965 Год назад

      What are you doing now brother

  • @abdulbasitkhan2589
    @abdulbasitkhan2589 8 лет назад +1

    can we use Iodine in this

  • @tiannamurray792
    @tiannamurray792 6 лет назад

    Hello Do you have a video for Friedel-Craft Acylation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  6 лет назад +3

      nope but it's essentially the same reaction just with an acid chloride instead of an alkyl chloride!

  • @songohan393
    @songohan393 5 лет назад

    Thank you

  • @bryannabueno2064
    @bryannabueno2064 3 года назад +2

    why am I payin all this money for school and learn nothing but RUclips is free

  • @Jorge-sv6pk
    @Jorge-sv6pk 8 лет назад +1

    you're the man

  • @sulafaalsammarraie9681
    @sulafaalsammarraie9681 5 лет назад +1

    You are the besttttt love you my lifesaverrrrr

  • @mohammadasifkhan3087
    @mohammadasifkhan3087 9 лет назад

    why hydroxylation take place at the end of Friedel craft acylation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 лет назад

      +Asif Khan Mohammad no hydroxylation, there's a carbonyl group that was already present in the acyl chloride.

  • @julianlidberg7590
    @julianlidberg7590 4 года назад +1

    I´m writing my exam from home while watching this xd

  • @namanemo5591
    @namanemo5591 5 лет назад

    Love you prof ❤️

  • @muramasa7537
    @muramasa7537 6 лет назад

    Nice ! My book had only 1 line n the figures n didnt understand but now after watching this i do !

  • @abhishekchunduri8285
    @abhishekchunduri8285 8 лет назад

    Sir, and why can't Vinyl halides and Aryl halides undergo Friedel Crafts Alkylation..whereas...a double bond involving molecule like Acyl group..undergo Fridel Craft Acylation..??

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 лет назад +1

      it's because friedel-crafts alkylation involves the formation of a carbocation on the alkyl fragment as an intermediate in the mechanism, and carbocations are highly unlikely to form on sp2 carbons.

    • @abhishekchunduri8285
      @abhishekchunduri8285 8 лет назад

      Thanks

  • @lauravaranasi6911
    @lauravaranasi6911 3 года назад +1

    helpful!

  • @Smaileymaile
    @Smaileymaile 6 лет назад

    What's the difference of alkylation and aceylation

  • @broccoli1020
    @broccoli1020 5 лет назад +1

    the question is how much should AlCl3 be used in this reaction?

  • @rayyvon18
    @rayyvon18 8 лет назад +2

    Can you make a video on acetylation?

  • @MuhammadHamza-fl7rn
    @MuhammadHamza-fl7rn 7 лет назад +1

    please use full representation its hard to understand those I'm not saying I don't know that but its easy the other way

  • @ankushvasireddy8871
    @ankushvasireddy8871 4 года назад +5

    This day marks the birth of Jesus

  • @abhishekchunduri8285
    @abhishekchunduri8285 8 лет назад

    Sir, can u please do a video on Friedel Crafts Acylation??..it really is confusing ...only u can explain it in a crystal clear way...

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 лет назад +3

      it's very similar to the alkylation! you can google the mechanism and email me if you have any questions.

  • @chem.chemistry1122
    @chem.chemistry1122 4 месяца назад +2

    🎉

  • @saptarshisahoo5075
    @saptarshisahoo5075 9 лет назад

    Can anybody explain me mechanism of Blanc chloromethylation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 лет назад +1

      +Uzumaki Saptarshi the oxygen interacts with the zinc atom to form an oxonium species, which is highly electronegative. this intermediate is what the arene reacts with.

  • @lauravaranasi6911
    @lauravaranasi6911 3 года назад

    very helpful**

  • @tastethejace
    @tastethejace 10 месяцев назад

    God this makes law school seem so easy in comparison lol

  • @ballights445
    @ballights445 3 года назад

    5 years later...

  • @bw6329
    @bw6329 4 года назад +2

    May Allah bless u

  • @SchizoaffectedGamer2112
    @SchizoaffectedGamer2112 4 года назад +1

    What ?

  • @pri173
    @pri173 10 месяцев назад +2

    I think he looking like ranveer kapoor😅

  • @nishalgoud2286
    @nishalgoud2286 9 лет назад

    how to study organic chemistry for jee mains

  • @dallincarroll
    @dallincarroll 8 лет назад +1

    Dude, you look like Said from Lost.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 лет назад +3

      never saw it! i hope he is handsome.

    • @TheSaddestCodPlayer
      @TheSaddestCodPlayer 8 лет назад +2

      He's gorgeous, definitely a close second to Dave. Unfortunately, Said just doesn't know enough Ochem to keep me watching him everyday. Dave doesn't have that problem; he's too busy solving mine!

    • @hamedhosseini4938
      @hamedhosseini4938 8 лет назад

      Haha nah professor is Italian origin, said is Indian origin.

  • @arnoldstephen5668
    @arnoldstephen5668 5 лет назад +4

    anybody 2019

  • @nirapsingh9773
    @nirapsingh9773 2 года назад +1

    Professor please seach this vieo up and explain this , type quantm computer and jinn demons in youtube .

  • @Khademaljawaden
    @Khademaljawaden 8 дней назад

    مستنصرية مرَّ من هنا

  • @Eric-sq4hd
    @Eric-sq4hd 4 года назад

    don't you mean chlroine is contributing 6?
    therefore has a +1
    well done. only video on this done in 3 min.

  • @MeganWatson-qg7oh
    @MeganWatson-qg7oh Год назад

    ilyyyyyyyy

  • @juanananth
    @juanananth 6 месяцев назад +2

    Jesus?

  • @elyaazmi8863
    @elyaazmi8863 4 года назад

    Sir, Can you just translate to indonesian, im not be able to speak english well

  • @aabhamahawar770
    @aabhamahawar770 6 лет назад

    Pure Indian lgta h

  • @microman_mathtiiaasrosen
    @microman_mathtiiaasrosen Год назад +1

    close this channel

  • @9691ark
    @9691ark 4 месяца назад

    I'll bet this whatever it us can't even change a tire!😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂

  • @avelandara3823
    @avelandara3823 Год назад +1

    thank you