Biochemistry of Starvation : Metabolism during Starvation || Metabolic changes during Starvation

This video is about :
Metabolism during Starvation
Biochemistry of starvation
How human body adapts to metabolic changes during starvation
During starvation, the body undergoes several metabolic changes as a result of the prolonged absence of food intake. These changes are adaptive mechanisms that help the body conserve energy and maintain essential functions. Here are some of the key metabolic changes that occur during starvation:
1. Glycogen depletion: Initially, the body relies on its stored form of glucose called glycogen, which is primarily stored in the liver and muscles. During the early stages of starvation, glycogen stores are rapidly depleted to provide glucose for energy.
2. Gluconeogenesis: Once glycogen stores are depleted, the body initiates gluconeogenesis, a process in which non-carbohydrate sources such as amino acids from muscle proteins and glycerol from adipose tissue are converted into glucose. Gluconeogenesis helps maintain blood glucose levels, which is crucial for providing energy to the brain and other glucose-dependent tissues.
3. Ketosis: As the body continues to be deprived of carbohydrates, it shifts its fuel source from glucose to fats. In a process known as ketogenesis, fatty acids are broken down in the liver to produce ketone bodies, including acetoacetate, beta-hydroxybutyrate, and acetone. These ketone bodies serve as an alternative energy source, particularly for the brain, to preserve glucose for essential functions.
4. Increased fat utilization: During starvation, the body becomes highly efficient at utilizing stored fats as an energy source. Fatty acids are released from adipose tissue and transported to the liver, where they undergo beta-oxidation to produce acetyl-CoA, which can enter the citric acid cycle (Krebs cycle) to generate ATP.
5. Muscle protein breakdown: In prolonged starvation, the body starts breaking down muscle protein to release amino acids for gluconeogenesis. This process helps preserve glucose for the brain but can result in muscle wasting and loss of lean body mass over time.
6. Reduced metabolic rate: To conserve energy during starvation, the body reduces its metabolic rate. This decrease in metabolic rate helps slow down the rate of energy expenditure, conserving the body's limited energy resources.
Overall, these metabolic changes during starvation are adaptive responses aimed at maintaining essential functions and preserving energy stores. However, prolonged starvation can lead to significant physiological and nutritional deficiencies, resulting in severe complications and potential organ failure.
Thank you for watching .If you like it,like share and subscribe to my channel 👍❤️🙏
#biochemistry
#biology
#fasting
#starvation
#metabolism
#biochem
#neet
#adaptation
#metabolichealth
#carbohydratemetabolism
#hormones
#carbohydrates
#proteinmetabolism
#lipidmetabolism
#fats
#protein
#brainfacts
#whathappensinfasting
#metabolicintegration
#mbbs
#bds
#physiotherapy
#nutrition
#dieting
#fastingfacts
#metabolicintegration
#

[@mishraji9871]

Tq sir ...nice explain 🙏

[@biochemistryconcepts]

Thank you so much for your feedback 👍😊💐

[@ahimsayamoah7696]

Hello can I get ppt on biochemistry of vision and immunity?

[@biochemistryconcepts]

Have you checked here :t.me/biochemistryconceptss
Check Here,if not available ,let me know,I will try

[@ahimsayamoah7696]

I have checked into detail and didn’t find it. Hope you can help

[@biochemistryconcepts]

Ok
I will try my best 👍

[@biochemistryconcepts]

Immune system uploaded.Check in telegram

[@ahimsayamoah7696]

Saw it immediately. Thank you