Peripheral T cell Tolerance - Clonal Deletion and Anergy (FL-Immuno/78)

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Easy to follow, I really thank god your channel is existed👌🏻👌🏻you’re the best.

[@FrankLectures]

Glad to know that these videos are such a help to you all. 😊 Thank you for your valuable feedback.

[@yilkalamlaku4414]

the most interesting and easily understood explanation, keep forward presenter.

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great explanation ....now I feel I can atleast write something in my exam....💞

[@FrankLectures]

Thanks

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I now understand better ❤️

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Perfect explanation ever!

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Thanks for saving my life.

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[@FrankLectures]

Thank you for appreciating these videos.

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[@FrankLectures]

Thank you for your feedback.

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This video is more than perfect
What if I did know this channel when I was a student

[@mahmoudahmed3468]

this kind of videos makes you want to know more

[@usmansaleem6135]

Very good explanation,
Kindly explain peripheral tolerance attained by CD8 cells specifically in separate video

[@martinasunflower4949]

Great explanation ! Thank you:)

[@FrankLectures]

Thank you for your feedback.

[@shwetapatel-bq4st]

All of ur videos are sooooo helpful... I request u to please please upload videos on different cell signalling and signal transduction pathways.... Please....

[@FrankLectures]

Cancer biology lecture series will be followed by Cell signalling lecture series. But it'll take time. Thanks.

[@shwetapatel-bq4st]

@@FrankLectures that's fine.. Thank u soo much...

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Best explanation ❤️

[@omegaphillip6863]

Nice explanation easy to follow

[@nadasaeed5422]

thank you so much . great , simple and conclusive

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Appreciated 💕💕💕 I understood it very well.😊

[@FrankLectures]

Thanks

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Excellent man

[@sahirajaafar1470]

Thank you and have a nice day sir! Xoxo

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Saved me

[@adamprabowo4556]

All was great! But one thing in minus, the voice shouldnt made by google translate or robotic :) Thaaaanks a lot

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such great videos...thank you :)

[@FrankLectures]

Thank you for appreciating these videos.

[@tanusreehalder3557]

Please make videos on post transcription and translation modifications..

[@saramorphy683]

thank you so freaking much

[@florramirez4521]

Really clear! thank you

[@Talal2430]

really good video

[@FrankLectures]

Thanks

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Helpful vedio
Thanks..

[@FrankLectures]

Thanks

[@vincentgogh2389]

Really well explained.

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Excellent 👌👌👌

[@FrankLectures]

Thanks

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Thanks from Indian occupied Kashmir

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thanks

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That was useful ..

[@noraahmed6135]

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[@AmritaPBB]

well explained

[@subinbyclema]

Central T cell Tolerance peripheral tolerance mechanism peripheral clonal deletion Anergy Treg prevent T cell activation control immune response maturation of DC danger signals (cytokines, complement, microbial products)

[@subinbyclema]

Peripheral tolerance Anergy Immune privilege prevent T cell activation control Immune responses maturation of DCS T cell activation

[@subinbyclema]

Co stimulatory molecule PRR, B7 (DCs)peptide-1. MHC complex- TCR lymph node- naive T cell(2. CD28) 3. cytokines auto reactive T cells self Ag source of self antigen no co-stimulatory molecule apoptosis apoptosis programmed cell death 1. peripheral clonal deletion 2. anergy(remain inactivated) prevent of auto reactive T cell activation.

[@subinbyclema]

Immune deviation previlege immunosuppressive cytokines TGF-B IL-10 blocks APCs, Treg

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[@wakylaugh]

💕💕💕

[@aliayad8444]

Nice

[@vikasraghuvanshi8551]

Nice.....

[@FrankLectures]

Thank you

[@mudassariqbal6874]

Aslam u alaikum Sir
Sir i need your help
Please guide me
I have read photorespiration from my book here there is a line that
(In most plants photorespiration reduces the amount of carbon fixed into carbohydrates by 25%)
The question is here that how 25% ???
How exect 25%???
Please help me
I have also searched from google but no satisfaction!!!!!

[@FrankLectures]

Waalaykumu assalam!
Answer to your question is little bit complicated. But let me try to explain.
In normal Calvin cycle all the carbons which enter the cycle as CO2 are fixed in the form of carbohydrates. So, amount of carbon fixed in Calvin cycle is 100%.
But if you have studied photorespiration in detail, you should know that when O2 is added to RuBP, two phosphoglcolate molecules are required to produce two glycine molecules. In a series of reaction one molecule of 3-phosphoglycerate (3PG) is produced which is fixed by Calvin cycle.
Net reaction is...
2 Phosphoglycolate (4C) + O2 -----> 3PG (3C) + CO2
Here, out of 4 carbons, only 3 are fixed in photorepiration. If you take out percentage of carbon fixed, that is, 3/4*100= 75%. So, 75% carbon is fixed. Remaining 25% is not fixed. It is released in the form of CO2.
So, "in most plants photorespiration reduces the amount of carbon fixed into carbohydrates by 25%".
You can study this concept in the book.....
" LIFE the science of biology, Sadava"
I hope it is helpful to you.
Thanks

[@mudassariqbal6874]

Frank Lectures
Thank you sir
Now my all concepts are clear
You are great sir
Love you❤❤❤

[@FrankLectures]

Glad to know this.

[@tammamzouihed3371]

If only the voices weren't google translate it would've been better , I was annoyed by them and couldn't concentrate

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