Peripheral tolerance | clonal anergy | Negative co-stimulation | peripheral deletion | USMLE step1

[@bili4591]

Yes but how these auto reactive cells are recognized ?
And apart from that
how « sur-stimulation » can be dangerous for the host when it is impossible to a cell to recognize host to be a « danger » ?
they all passed the test to don’t attack the host so ... why ?

[@Rowe_Ti]

Does a similar mechanism works for allergen tolerance as well?

[@animatedbiologywitharpan]

Nope