Intrinsic vs. Extrinsic Coagulation pathways - Hemostasis - Bleeding and Coagulation

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  • Опубликовано: 21 дек 2024

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  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  5 лет назад +11

    💊Antibiotics Lectures: www.medicosisperfectionalis.com/

  • @jezelqueentaguinod4141
    @jezelqueentaguinod4141 5 лет назад +79

    You’re such a big help to me. Medschool is so stressing but you make it bearable. 😊

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +11

      Thanks a million, dear!
      I am glad you liked my videos.
      Can you please help me by sharing my videos with your friends?

  • @jlynnbolster
    @jlynnbolster 5 лет назад +45

    All of your videos are incredible. Thank you! Your dry humour makes learning these concepts too much fun

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +5

      Thanks again...You’re such a great, kind-hearted person...You made my day 😊

  • @سارةطارق-م2ي
    @سارةطارق-م2ي 3 года назад +20

    im a proud arab ! even though im not egyption but still bro all the middle east should be proud of u

  • @StevenMP1993
    @StevenMP1993 Год назад +3

    Wow! What my Hematology professor couldn't teach me in two classes, you taught me in 9 minutes. Thank you!

  • @sishabell8474
    @sishabell8474 Год назад +2

    If I get too bored with the medical lectures , because as you know they are too much 😓, watching your videos make me feel better,and I begin to study them again... Thank you... and keep going.

  • @hagarmabrouk5327
    @hagarmabrouk5327 5 лет назад +5

    I am an Egyptian . And study pharmacy
    Thank you for this vedio 💙. It is very interesting, but it is very brief. There is an absence of many enzymes and substances important for clotting😥

  • @rakafarjana244
    @rakafarjana244 3 месяца назад +1

    Thank you 😊 it's too effective
    From Bangladesh 🇧🇩

  • @geo.ies93
    @geo.ies93 4 года назад +4

    “Boom, boom, boom, boom, boom, boom, boom!” 😂😂😂
    Thanks a lot. You’re amazing. 🙌🏻👍🏻

  • @-journey-6527
    @-journey-6527 11 месяцев назад +1

    thank you for all your videos !! YOU ARE THE BEST !!

  • @drhussainspeaks7294
    @drhussainspeaks7294 Год назад +1

    10/10......deserve special credit

  • @SmsM-em4oy
    @SmsM-em4oy Год назад

    Im in love with medicine because of you 😂😂

  • @Maryjcorder
    @Maryjcorder 4 года назад +2

    Great explanation of pathophysiology on a cellular level

  • @miarania4079
    @miarania4079 4 года назад +5

    i always love all medicosis' videos. Lots of fun in studying medicine! Thank you so much ^.^

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +1

      My pleasure 😇
      Can you please help me by sharing?

    • @miarania4079
      @miarania4079 4 года назад

      @@MedicosisPerfectionalis absolutely, sure!

    • @sayehsayar2339
      @sayehsayar2339 4 года назад

      @@MedicosisPerfectionalis How can I have access to your cases you mention in videos?

  • @amnatariq8338
    @amnatariq8338 11 месяцев назад

    My pathology final saved omggg thankyouu

  • @gauravpawar1794
    @gauravpawar1794 5 лет назад +4

    Subscribed ur channel best thing I ever done in my life

  • @fa5774
    @fa5774 5 лет назад +4

    I can't stop laughing!!! The hashtags lol! Ur sense of humor is awesome. Thx for making life easier.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +1

      You’re very welcome 😉
      Thanks for your encouragement.
      Can you please help me by sharing?

    • @fa5774
      @fa5774 5 лет назад +1

      Medicosis Perfectionalis yup!! Sent it to a bunch of my med school friends! It’s helping so much!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад

      That’s awesome 👏
      Thanks, dear!
      Let me know if you have any questions.

  • @hannahrosa5485
    @hannahrosa5485 5 лет назад +2

    I love your sarcasm. You always make me laugh.

  • @Razannnxo
    @Razannnxo Год назад +2

    Doesn't extrinsic coagulation start from clotting factor III as opposed to VII? Thank you a lot for the video!

    • @Stubborn214
      @Stubborn214 Год назад +1

      Factor 3 is just tissue factor, so even my proff said that it starts with 7 although, factor 3 is the starter, but there’s nothing wrong with that.

  • @rishabhparakh5034
    @rishabhparakh5034 4 года назад +1

    In love with your explanation. Truly Out of the box!!😁

  • @kingfreefire1843
    @kingfreefire1843 2 года назад

    Good teacher I follow you from Syria thank you

  • @johnareyes8938
    @johnareyes8938 3 года назад +1

    This is such a big help! Thank u for rescuing my grades hahaha

  • @إيثارنظامالدينحافظعارف

    Your explanations are incredible .they enter my mind against my will 😂,could you tell me the programs you use in the video i'll appreciate it.

  • @hamdasn7291
    @hamdasn7291 3 года назад

    2:49 which Video is an explanation about "vasoconstriction" ?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      This one: Hemostasis Introduction:
      ruclips.net/video/1_-ZPbq-vDI/видео.html/

  • @Ghaffar_KH
    @Ghaffar_KH 4 года назад +3

    I know this is late, but thank you so much for the video!

  • @000-l9e2q
    @000-l9e2q 3 года назад +2

    I love you and I love the way you teaching 😍💖
    I appreciate the amount of hardship and effort you spend on these amazing videos. I will pray for you to reach a million followers and more on youtube.🙏🌹
    God bless you 🙏🙏keep going💐💐💐

  • @mohammadalbakheet57
    @mohammadalbakheet57 Год назад

    How can I find the cases ? Because I searched his page on Petreon but I see is videos

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад

      You can find them on my website: www.medicosisperfectionalis.com/
      If you have any questions, email me: medicosisperfectionalis@gmail.com

  • @sayehsayar2339
    @sayehsayar2339 4 года назад +1

    How can I have access to your cases you mention on videos?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад

      The 50 hematology cases: www.medicosisperfectionalis.com/products/50-hematology-cases/

  • @ceehaychh
    @ceehaychh Год назад

    Hello. Can you explain FXIa inhibition and how it compares to FXa

  • @snehavimal5772
    @snehavimal5772 5 лет назад +2

    Amazing video, within few minutes we can revise congulation cascade, thanks sir

  • @haider97majeed
    @haider97majeed 5 лет назад +1

    How do I communicate with you ?

  • @haider97majeed
    @haider97majeed 5 лет назад +3

    I am from Iraq 🇮🇶 😍😍😍

  • @fizzaiqbal8898
    @fizzaiqbal8898 4 года назад

    You made it so easy and precise. Thank You.

  • @estherssebbowa3043
    @estherssebbowa3043 4 года назад +2

    Thank you - yes making perfect sense for sure - well done

  • @snowdiamond5740
    @snowdiamond5740 5 лет назад +5

    You're the hero ♡ thank you

  • @islamshorman959
    @islamshorman959 5 месяцев назад

    Really incredible
    big love ❤❤

  • @piapiaibrahim4339
    @piapiaibrahim4339 2 года назад

    Is that L.A you guys are always showing at the beginning of the vid?

  • @shreesomeshchoudhary481
    @shreesomeshchoudhary481 Год назад

    incredible explanation and representation too......i have one doubt.....in the intrinsic pathway does leakage of blood out of the blood vessels occur? kindly respond

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад

      Any injury to the blood vessel (e.g. finger prick or paper cut) will lead to leakage of blood out of the vessel (whether it’s intrinsic, extrinsic, or both).

  • @fatmamohammed6924
    @fatmamohammed6924 3 года назад

    One question,isn't the tissue thromboplastin considered factor III ???!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад +1

      Correct!
      That was discussed in later videos.

    • @fatmamohammed6924
      @fatmamohammed6924 3 года назад

      @@MedicosisPerfectionalis oh my bad I've started the playlist recently.on a side note really enjoying your great work and recommending your channel to everybody👏👏👏👏

  • @lenethlopez6383
    @lenethlopez6383 3 года назад +1

    I should quit med school and enroll in Medicosis Perfectionalis. Hello from the Philippines

  • @abhinavrajiv986
    @abhinavrajiv986 Год назад

    Do both pathway run simultaneously...?? You said in extrensic means something we need from outside...why we need from outside.... clotting only occur when there is rupturing of blood vessels occur....

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад

      From the outside means: “from outside the vascular lumen itself” such as the tissue factor.

    • @abhinavrajiv986
      @abhinavrajiv986 Год назад

      @@MedicosisPerfectionalis but why we require from outside....?

  • @sahr366
    @sahr366 2 года назад

    A random question have you ever considered collaborating with/working for Osmosis?

  • @ahmedhany6203
    @ahmedhany6203 3 года назад +1

    man i just knew ur egyptian and I'm so proud, heads up I'm from Alex med

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад +1

    📝 Download my handwritten notes: www.medicosisperfectionalis.com/

  • @حجيطالب-ذ1د
    @حجيطالب-ذ1د 3 года назад

    لا أفهم معنى كلمات الأغنية ولكن الأحساس رائع😍😍❤

  • @tinyyy99
    @tinyyy99 5 лет назад +8

    I want him to be my prof 😆😄

  • @Tobias-uo7vo
    @Tobias-uo7vo 3 года назад

    Masterpiece for understanding!

  • @mohammedkadir3437
    @mohammedkadir3437 Год назад

    amazing explanation!

  • @rekhachaudhary906
    @rekhachaudhary906 3 года назад

    U r so amazing 👏 u explain it in so simple and effective way....thank u so much

  • @medicalscience1528
    @medicalscience1528 2 года назад

    Hello, I thought that in intrinsic pathway injury occurs by something wrong within body while extrinsic is from outside like cutting finger with knife. But its not this , right?
    It is not based on how we get injured but how we get healed right ?
    Like healing factors are all from blood in intrinsic while factors can come from endothelial etc in extrinsic ? Kindly clear if I'm right here !!
    Thank you.

  • @Linkfan007
    @Linkfan007 3 года назад

    oh my god, this video was soooo good!!! thank you! you're awesome, love how you explain this!! :D

  • @muhammadaliaslam4023
    @muhammadaliaslam4023 3 года назад

    Sir can we say ADP dependent Expression of GPllb and GPllla is an example of Autocrine?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад +1

      Because ADP is secreted from the platelet and acts in the platelet (auto = self).

  • @rou9409
    @rou9409 5 лет назад

    is it necessary to follow each factor by its number? or just understand the way factors work?

  • @Choogaleh
    @Choogaleh 5 лет назад +3

    Amazing teaching!

  • @murukeshtimetvm4119
    @murukeshtimetvm4119 3 года назад +1

    Thank you sir 🙏

  • @leymer13
    @leymer13 4 года назад

    Hey Medicosis, I love your videos. Is there any chance that you might add blood bank videos.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад

      It’s a good idea!
      Where do you study from? 📖

    • @leymer13
      @leymer13 4 года назад

      Medicosis Perfectionalis thanks for replying. Are you asking from where in the US I study or from what book I study. If so I’m from NY and the book I study from is called Basic & Applied Concepts of Blood Banking and Transfusion Practices 3rd edition. I hope I was able to answer you question.

  • @hotothezey9620
    @hotothezey9620 5 лет назад +1

    Huge help! Thank you

  • @DrAdnan
    @DrAdnan 5 лет назад +3

    Warfarin vs heparin, ext vs intrinsic 💪

  • @diamondminor
    @diamondminor 3 года назад

    What's up dude, watching the vid, noticed how you pronounced "balance" with extra emphasis on the a's. where's your accent from? Germany?
    Thanks bro :)

  • @SakshiRanematriks
    @SakshiRanematriks 2 года назад

    How to remember that intrinsic pathway - PT and ext- aPTT

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад +1

      The shorter pathway (extrinsic) has a shorter word (PT) and vice versa.

    • @Stubborn214
      @Stubborn214 Год назад

      See, PT-play tennis(outside and ex mein outside although it occurs inside but just for the sake of learning) PT-play tennis(extrinsic)
      PTT(play table tennis-intrinsic) indoor

  • @nived8476
    @nived8476 4 года назад

    Doesn’t HMW kininogen (or prekallikrien) work with XIIa to activate XI?

  • @QassamAlaa
    @QassamAlaa 5 лет назад

    thanks alot .but there's missed point for me .. in our body do both work at the same time to prevent blood loss in the same injured tissue ? i mean do both work at same time and support each other.. if not then what makes body follow intrinsic or follow extrinsic?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +1

      Both happen at the same time.

    • @QassamAlaa
      @QassamAlaa 5 лет назад

      Medicosis Perfectionalis then we can live with one pathway😅

    • @QassamAlaa
      @QassamAlaa 5 лет назад

      Medicosis Perfectionalis then we can live with one pathway😅

  • @mahdersolomon2907
    @mahdersolomon2907 2 года назад

    Wowww empresses me God bless you

  • @samyak20
    @samyak20 5 лет назад +1

    You sir are just amazing.🤯😃

  • @rutabaarif1512
    @rutabaarif1512 5 лет назад +1

    I don't know whether to be happy or to be sad I've done blood module twice once in first year then in third and now in my final year only I've understood how intrinsic and extrinsic pathway starts

  • @user-uq3tb1qe1h
    @user-uq3tb1qe1h 3 года назад

    You are amazing!❤️🙏

  • @morenikeangel6948
    @morenikeangel6948 3 года назад

    Thank you😍😍

  • @DudeItsCzar
    @DudeItsCzar 5 лет назад +2

    You're Awesome!!!!!!! THANK YOUUUUU

  • @이정현-l9j
    @이정현-l9j 4 года назад

    Thanks for the nice video!! By the way, can you help me to find reference for effect of intrinsic pathway is stronger than extrinsic pathway?

  • @noorhamed4690
    @noorhamed4690 5 лет назад +2

    Very good ,

  • @sathakamara1324
    @sathakamara1324 2 года назад

    Where is factor 3?

  • @chiamakaeze6456
    @chiamakaeze6456 5 лет назад +2

    Thank u very much😊.

  • @Mimi-lf7tq
    @Mimi-lf7tq 4 года назад

    This helped a lot 🥰

  • @ss3603
    @ss3603 2 года назад

    Brilliant!!

  • @jasminemh5664
    @jasminemh5664 4 года назад

    Ohhh so helpful translated to Arabic 😍🤗

  • @rawnakfardeen2330
    @rawnakfardeen2330 2 года назад +1

    Great ❤

  • @swathiraja875
    @swathiraja875 4 года назад

    Can you please tell me why ptt for intrinsic and PT for extrinsic?? And ur videos are excellent!! 😍

  • @farahhashim2590
    @farahhashim2590 4 года назад

    Thank you👍

  • @mariya5605
    @mariya5605 5 лет назад +1

    Thanks alot

  • @aliahmedqasim9324
    @aliahmedqasim9324 2 года назад

    forgot to say the mighty intro

  • @cg2158
    @cg2158 4 года назад +2

    studying this during a global pandemic because nursing school is NOT cancelled

  • @ayaeid136
    @ayaeid136 3 года назад

    Thank u ❤️

  • @charizardmcqueen6259
    @charizardmcqueen6259 5 лет назад +1

    You make it so easy compared to Guyton and Hall. HAHA

  • @salwaahmed3553
    @salwaahmed3553 2 года назад

    مافيش مترجم للفهم اكثر

  • @urbanproductions5584
    @urbanproductions5584 4 года назад +2

    Why do u sound like me when my math teacher scolds me up for getting 3 out of 100 in each and every test 😔

  • @viraltiktokviraltiktok1524
    @viraltiktokviraltiktok1524 4 года назад +1

    NICE TEACHING.... YOU REALLY ARE FUNNY!

  • @dragutte3742
    @dragutte3742 4 года назад

    and where is VI? :)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +1

      Doesn’t exist!
      It was named after a protein that was later discovered to have no relation to coagulation.

    • @dragutte3742
      @dragutte3742 4 года назад

      Oh Oke thanks, our Hematology prof had no idea about it, I always wondered why they did skip VI :)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +1

      Haha 😂
      Professors drive me crazy 😜
      Thank you so much for watching my videos...It means a lot to me!
      Good luck 🍀

    • @dragutte3742
      @dragutte3742 4 года назад

      They drive me crazy as well, always want us to memorize stuff and tell it like a parrot, prolly they dont read best textbooks idk, but Medicine makes sense man as you said. I think 90% of Medicine is logical, rest 10% we dont know the logic behind it 'yet' 😛 Keep up the good work man, you are doing great.

  • @leilam7891
    @leilam7891 5 лет назад +2

    Thank you

  • @MBBSLOVER786
    @MBBSLOVER786 Год назад

    Tysm

  • @amber8285
    @amber8285 5 лет назад +3

    you always make me laugh with ur sarcastic comments :')

  • @louisedingle9949
    @louisedingle9949 3 года назад

    thankyou.

  • @m2rwah
    @m2rwah 4 года назад

    don't tell me to study hard, i get anxiety!

  • @stephen5709
    @stephen5709 9 месяцев назад

    thank u

  • @EylulTurksever
    @EylulTurksever Год назад

    Medicosis, Why do you hate alpha globulins so much? You always mention the beta and the gamma globulins but never tell the function of the alphas :(
    2 of them are even related to the hemostasis: alpha-2-antiplasmin and protein C

  • @aryan2065
    @aryan2065 5 лет назад +2

    u r awesome

  • @oats4454
    @oats4454 Год назад +1

    Really deeep😂😂

  • @alishapaudel8332
    @alishapaudel8332 5 лет назад

    You sound like Shawn Mendes😁

  • @aliahmedqasim9324
    @aliahmedqasim9324 2 года назад +1

    you should have predicted me being here
    oh believe me iam typing this comment even before watching the video
    at one point you wont have anything else to do only to answer my comments 😈😈😈😈

  • @gothicangel160
    @gothicangel160 5 лет назад

    #gravity

  • @juliamoore542
    @juliamoore542 3 года назад

    Hello, veterinary medical school student here. Just wanted to let you know that the pointer finger of your hand drawing has an extra knuckle in it. (Maybe this is normal for humans, I wouldn’t know, I just study every other mammal and reptile in the world) P.S. love your videos ❤️