Haemostasis 2 - Coagulation Cascade

www.handwrittentutorials.com - This tutorial is the second in a series of three on the topic of Haemostasis. This video explores the Coagulation Cascade and all the Factors involved. For more entirely FREE tutorials and the accompanying PDFs visit www.handwrittentutorials.com

[@doctorkimcruises]

I cannot believe how simple it actually is but our presenters made such complicated annotations with confusing markings and an unwelcoming font. This was great!

[@ranatarek7909]

a

[@Shubham_9898]

you are right

[@mimiwitter]

All the years Iv been studying and scouring the internet for little bits of simply put explanations, this is one of the nicest and easiest videos to follow. I'm not one to usually comment on things, but I feel like this deserved a big thank you! Love the videos, please keep it up! :-)

[@FuseFrome]

I could not understand Coagulation Cascade for long time but your tutorials which is long just 4 mins can make me clearly understand and also I can remember it. Thank you so much.

[@miting9292]

Hello there! I'm back after 5 years. I used to watch your video and incorporate it whenever I study back in college. And all of them helped me a lot. Thank you so much. God bless! *i always fell asleep whenever I read the whole chapter of the book, so this video saved me from all the reading that usually don't get into my mind*

[@drjsm]

I saw this video 9 years , back then I had just entered med school..
Now in 2023, im watching it again for my MS exam...
Time flies...
Thank you

[@Maryam0961]

Simple, directly to the point... I love it
that's what's missing in our classes

[@wsheri11]

THANK YOU SO MUCH!!! People really make things harder than what it is! I saved so much time watching this video!

[@KatieDeGo]

I watched literally 2 hours of videos before I FINALLY FOUND ONE I UNDERSTOOD! THIS ONE! THANK YOU!

[@imtiaz518]

They are just wonderful and especially for the undergraduates and postgraduates as well, just keep it up and keep posting more and more ...thanks once agasin

[@ilaportiaC]

This is just perfect! Thank you for clearly explaining what my textbook couldn't do

[@bbmeesci5950]

I have watched countless videos trying to grasp this concept in time for my exam and this was by far the easiest to remember.

[@MizzRiverP]

This was wonderful! Thanks! You must continue the good work!

[@AnimeshMandal_]

Thank u .... This was simply Awesome..... Undesrstood the thing in just 4 mins !!

[@heinsuniverse]

Best tutorial I've seen so far! Thanks a lot!

[@tashamumu]

This is great. I need to present this in class and this video helped me a great lot in summarising all the info I read, much thanks :)

[@nesseraabdel-gadir9380]

Amazing explanation
Thank you for your help. I have a question
What is the role of calcium in coagulation

[@visionarykannada]

Very super explanation actually ur vedio is more effective than others

[@inyoface987]

you have the best tutorials online!

[@toobatoobasalamatali9315]

Thanks 😊.
I can't tell you
How much easy you make this for me :)

[@carlongski]

These are so useful and clear. Thank you very much!

[@luyanrayayang8498]

I appreciate your work! It is so so so clear~

[@priscillepolla]

👌🏾👌🏾👌🏾 you just made me understand this so easily. Thank you so much

[@xxxHotChocoLate]

can you tell me if you have a video about the antagonists and the agonists and about the different receptors like endogene agonists. thanks a lot for your helpful videos :)

[@ilaydak2418]

Very helpful thank you! I was struggling with my med class notes.

[@ryanwilliams6478]

Dude, you killed that. Well done

[@eric-sunnynatangwekambonde1340]

this is the best, short but brief. Thanks a lot

[@ravindranathkamath1577]

Your Tutorial was one way helpful but at the same time you have forgotten I think.. That Factor 7 in the extrinsic pathway and Factor 9 in the intrinsic pathway require Calcium ions as their cofactors for the activation of the respective factors in their respective pathways.. :) :)

[@Sky-rq2gx]

Ravindranath Kamath right it's written in my book , but really he is amazing in explaining

[@heehoney7147]

I was thinking the same thing the factor 7 was helped by factor 3 and Ca2+ so it converted into 7 a, well its okay tho he can forget about something

[@ahealingplace7350]

Thank you

[@hossamashraf2692]

it haa been a great vedio.. thank you alot
but unfortunately i have to know their names which is hard to remember

[@productive_soul......728]

Thank u sooo much for ur amazing explanations

[@maheedhararavi8145]

Great presentation for lay person like me. I heard that Ca++(IV) is not considered a special factor as it is abundantly available around. Please correct me if I were wrong. Regards

[@obaahemaacandy9082]

The best explanation so far

[@EEinstein100]

comprehensive. Awesome and really helpful. Thanks a bunch tutor

[@stephenprice3357]

don't know what any of this means, i just memorized the entire video 🙌💁

[@pratitimukherjee614]

thanks immensely for making it sooo simple!

[@lm59olk]

Please can you update to do new cell based model? Intrinsic and extrinsic aren't taught anymore...

[@asantefelicia-j8g]

You made it very simple for me, thanks

[@riyadatta2405]

Great tutorial sir...👍😃
of great help n I can even wrt it for 1st MBBS paper with other details. I love the wrtn part...its great.

[@evaatan]

this guy has the same voice as that curly haired chef tutorial guy on the food network. love it

[@abdulmajeedalshahrani7113]

Most useful video in coagulation cascade , thx very much

[@richardmshanga5270]

thank you. this was very helpful

[@sushreejena5568]

Very good video sir ....thank you sir....sir please send videos on all topics of biochemistry and physiology

[@warimyeon881]

Thank you!! that was so helpful

[@Ndn1011]

Love it, but you didn't include factor 13? and calcium

[@sarahd7449]

Thank you so much this helped me a lot 🙏.

[@kavinraj3969]

is there any factor 13 ah??

[@hudatahera6399]

Thank you for this!📚

[@juliuslee2307]

you made it very simple. thanks!

[@shaikhaaldossari7122]

Very informative. Thanks a ton!

[@thusharikandamby4436]

Thank you so much. This clarified my doubts :)

[@maywryshan]

OMG!! So it was easy like this! thank you soooo much 🥺❤️‍🩹

[@StrangerInAuckland]

excellent tutorial! very helpful indeed

[@ibrahims.8074]

thank you
it really makes it too much easier

[@divyalovesyou9007]

Woooow thank you sooo much!!! Very helpful! So clear and well explained! Love yooou!! XD

[@JoeB-mv7pg]

Such a good tutorial!!

[@abishakdasgupta1454]

Where is the factor 4 used (ca++)

[@Pixydust143]

You didn't mention that the thrombin produced in the extrinsic pathway is not enough to activate conversion of fibrinogen to fibrin. The extrinsic pathway only enables the activation of intrinsic pathway from which you can generate enough thrombin to produce fibrin. Pretty important step to mention 😬
I do really like the style of the videos though :)

[@39himanshuzilka62]

Well explained.. 🎉 thanks..

[@hogueguy]

Does tissue factor activate VII? If not, what activates VII?

[@ME-xh5zq]

Yes

[@NabaaYousif0_1]

Excellent explanation thank you☺️

[@marymelsayed8279]

This was great!

[@sonofinternet]

can anyone explain how do scientists identify all these

[@alleycat4409]

Thank you, thank you soooo much 😭😭

[@Sky-rq2gx]

Thank you thank youuuu i was suffering from it 😂
Tomorrow is my practical exam wish me luck i don't know shit about hematology 🔥💔

[@bi0lizard1]

Basically it rains down Roman numerals until Prothrombin get converted to Thrombin. Then fibrinogen converts to Fibrin mesh (which all the platelets and crap stick to). Got it. Ty.

[@rittenbrake1613]

Simple, clear , effective

[@bravething2011]

thank you very much
that was helpful .

[@annahylten-cavallius1518]

This is great, thanks a lot!!

[@julianmilek4758]

JUST AWESOME. THANK YOU.

[@Imraan53]

You're amazing😘😘 thank you so much 😍😍😘😘

[@Imraan53]

I can't thank you enough!

[@enaskhazaleh6045]

That was helpful. Thanks!

[@colleencampbell6718]

thank you!!

[@LameesKH]

YOU SIR ARE AWESOME!

[@mariams8844]

amazing video, thanks

[@MrRafie93]

you forgot to include the factors that requires calcium ions to get activated. that's pretty much important though! so, in this case; i would add calcium with factor VIIIa to activate factor X, and would add it as well with factor Va to transform prothrombin to thrombin. In addition, i guess that u miss that VIIa in the extrinsic pathway can activate IX to IXa. Otherwise i like ur simplicity.

[@mortorque]

This is the Most important comment I was replicating my teachers work and was missing that

[@Tika422]

Nice presentation

[@somcana]

What initiated factor 12? Is it in active form always? Thanks

[@matthewvargas7177]

HMWK & Prekallikrein

[@priyankabhandari3192]

Wow its so amazing thank u so much

[@crissyr8132]

Great video. Thanks!

[@HafizahHoshni]

This is amazingggggggggg ! Thanks you helped me a lot !! XD

[@reemalhazza4868]

Thank you so much

[@xHaniffax]

Whose amazing idea was it to denote this cascade using roman numerals? /sarcasm

[@irone93]

Yeah, it's like it could not be anymore convoluted if you tried really, really hard.

[@Minshooga]

pretentious scientists probably lol

[@jdeleon724]

...Probably to differentiate it from the complement cascade that uses Arabic numerals?

[@msers541]

How stupid are you that you can't read Roman numerals?

[@heehoney7147]

My professors did the thing too probably to differentiate it and so it'd help you when you're actually try to remember the scheme

[@Yranjana]

It is OK but u have not discussed about calcium ion

[@user-hd2ms4ll4h]

Thank you very much !!

[@siddlingatthar1326]

Superrrrrrb sir so helpful

[@sugarchowchow]

Excuse me but you forgot to add factor IX which is needed for stabilizing the fibrin clot and it was activated also by thrombin :)

[@muhammadbilal7582]

ooooo... time saver ....thank you.

[@rii9535]

After watching this vid it's easier for me to understand now and I realized that our teacher made mistake about the the extrinsic and intrinsic pathway's😬

[@adolflichtfusz6213]

Thank you man

[@soumyakizhakedath474]

excellent one

[@Kojogh]

Omg I love this guy #nohomo ..... I have a final tomorow , this is my intervention 💯

[@safesoundequine8511]

My hero

[@al_akseer2087]

God bless you ❤️

[@nuhamahmoud7682]

so interesting thanks ❤

[@minicat2743]

thank you so so much

[@maryamthamer9007]

the best!

[@vinitasolanki3627]

Thank you...

[@brownspicyrice]

thank you!

[@olaseindefavour966]

This is nice

[@user-kp1lo7qh7y]

Thank so much