Coagulation Cascade - Easy Way To Remember Intrinsic vs Extrinsic Pathways | PT or PTT?

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  • Опубликовано: 21 дек 2024

Комментарии • 143

  • @PiyushKumar-lg9is
    @PiyushKumar-lg9is Год назад +65

    Play table tennis and play tennis, what an excellent way to remember diagnostic tests. Amazing clear and concise information

    • @RhesusMedicine
      @RhesusMedicine  11 месяцев назад +5

      Picked that one up in Medical School, has stayed with me!

  • @icymoorge
    @icymoorge 4 года назад +246

    This video is very good. Clear, gives good mnemonics, I feel like I remember everything, I will be back in a few months when I forget it all again

  • @yadums1448
    @yadums1448 Год назад +12

    This was about 2 hours of reading compressed to 6 minutes. All the needed points and mnemonics .tysm

  • @nilsboller4651
    @nilsboller4651 7 месяцев назад +15

    You can remember Via-K-Ant with the year 1972 (10,9,7,2)

  • @clieolada3601
    @clieolada3601 9 месяцев назад +8

    Calcium is not Plasma Factor V, but IV. plasma factor V is labile factor/proaccelerin

  • @JK-jd1ir
    @JK-jd1ir 3 года назад +41

    This helped me recap the coagulation cascade for post-graduate exams. I especially liked how you included the clinical side of things with the blood tests and medications. Keep it up!

  • @K1312-s8d
    @K1312-s8d Год назад +3

    As an emergency doctor, this is an excellent recap of the clotting pathway and the relevant drugs.

    • @RhesusMedicine
      @RhesusMedicine  11 месяцев назад

      Thank you, appreciate the feedback!

  • @dumisanzama3901
    @dumisanzama3901 7 месяцев назад +5

    Vitamin K dependant factors: "1972 was the disco era" (1=10) 9,7,2 and diSCo=protein S&C) this has worked for me instantly after I had tried and failed to memorise them. I would always confuse them and would sometimes mix up the numbers after some time.

  • @FishoeShoe_da_great
    @FishoeShoe_da_great 6 месяцев назад +5

    that tennis mnemonic is just beautiful

  • @chibzyt5699
    @chibzyt5699 Год назад +2

    BRILLIANT BRILLIANT BRILLIANT video. The effort and ease for everyone you considered is just heartwarming. Really love this video.

    • @RhesusMedicine
      @RhesusMedicine  Год назад +1

      Thank you for the feedback, and for watching! 😊

  • @RhesusMedicine
    @RhesusMedicine  4 года назад +6

    Buy Us A Coffee!: www.buymeacoffee.com/rhesusmedicine
    For more medicine videos consider subscribing (if you found any of the info useful!):
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    Video Timestamps:
    0:00 Intro
    00:27 Intrinsic vs Extrinsic Pathways
    00:57 Common Pathway
    1:37 Easy way to remember intrinsic vs extrinsic pathways
    2:08 What is the difference between PT and PTT?
    2:48 What are the Vitamin K dependent clotting factors?
    2:55 What causes a prolonged PTT?
    3:09 What causes a prolonged PT?
    3:30 What causes a prolonged PT and PTT?
    4:04 Where in the coagulation cascade do different anticoagulants work?
    5:45 What are the antidotes to anticoagulants?
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  • @gagagig2895
    @gagagig2895 3 года назад +5

    Awesome! I try to read this topic by myself for half a day and still confusing but u make it clear in 6 mins. Thank you so much.

  • @jamiuadebiyi6778
    @jamiuadebiyi6778 3 года назад +3

    This is the best video on clothing factors so far.Thank you

  • @krutika8656
    @krutika8656 3 года назад +13

    So beautifully explained!! And you guys have managed to cover everything, in such a short time!! Thank you so much for this video! :) :)

  • @abdu_jilani
    @abdu_jilani Месяц назад

    Greatest video on the coagulation cascade!

  • @adamwalsh1977
    @adamwalsh1977 2 года назад +1

    Ur am you so much you make a complex algorithm more simple & REALLY liked the mnemonics. It’s the best way I learn & they defo stuck 👍🏻

  • @DrPBaptiste
    @DrPBaptiste 4 года назад +6

    Not an easy topic to cover but you've done it really well!

    • @RhesusMedicine
      @RhesusMedicine  4 года назад +1

      Thanks Dr Baptiste, I appreciate that! Hopefully provides an all in one video for people to come to for a refresher

    • @DrPBaptiste
      @DrPBaptiste 4 года назад

      Rhesus Medicine yes it was good for me!

  • @allisonsouter9589
    @allisonsouter9589 Год назад

    best video I have seen yet on this topic, thanks so much

  • @viona8897
    @viona8897 Год назад

    I just want to say a big big big thanks.
    I especially enjoyed the memory aids- really amazing!

  • @bakindeakindapo9618
    @bakindeakindapo9618 Год назад

    From the bottom of my heart, Thank you so much. I really really appreciate your explanation.

  • @rgvn5
    @rgvn5 2 года назад +27

    Ninja nerd taught me an easy way to remember: Intrisic pathway = 12 11 9 8, Extrinisic = 7 3, common pathway = 5 2 1
    Put 10 in the middle.
    Intristic pathway you count down except 10
    Extrinisic path way 7 + 3 = 10
    Common pathway 5 * 2 * 1 = 10
    Now you will never forget again

  • @wael9704
    @wael9704 10 месяцев назад

    Fantastic video! Love the clinical correlation and drug action mechanisms. Perfect for post-grad exams. V nicely done.

  • @rahulkumar-wf1dd
    @rahulkumar-wf1dd 3 года назад +3

    Been through a lot of videos, in search of this topic, it couldnt have been better 🙏
    Posting it at 3.45 a.m, my exam is in next 4 hours,
    Thank you

    • @RhesusMedicine
      @RhesusMedicine  3 года назад

      Thank you Rahul, the feedback means so much! Crush that exam- best of luck! 💪

    • @jaymorgan.
      @jaymorgan. 2 года назад +1

      Did you pass? This topic is still confusing to me. Lol

  • @arnavupadhyay5970
    @arnavupadhyay5970 4 года назад +3

    Really covered it all in so less! Great work!!

  • @JesúsEduardoPalaciosLópez
    @JesúsEduardoPalaciosLópez 2 месяца назад

    We should share this way of rememebering important topics

  • @theanonymouspotato1924
    @theanonymouspotato1924 10 месяцев назад

    i'm not being dramatic when i say this video probably saved my life

  • @razanabdullah1016
    @razanabdullah1016 3 года назад +3

    Clear, simple ,short and highly informative 👏🏼👏🏼👏🏼👏🏼 thanks

  • @zackabdihakim2737
    @zackabdihakim2737 Месяц назад

    Amazing lecture. Thank you very much.

  • @ICU_NERDSE
    @ICU_NERDSE Год назад +1

    you are so brilliant ! Thank you for this!!!

  • @lorifondren5583
    @lorifondren5583 Год назад +1

    This video is absolutely AMAZING! Thank you so very much for sharing it with us.

    • @RhesusMedicine
      @RhesusMedicine  Год назад

      Very glad it was helpful, thanks for watching :)

  • @OmnipotentO
    @OmnipotentO 8 месяцев назад

    Really nice "cheat sheet" style layout. Very useful

  • @seadimogladness2461
    @seadimogladness2461 5 месяцев назад

    Tennis mnemonic is really helpful. Thank you

  • @naveenkumar9215
    @naveenkumar9215 8 месяцев назад

    This video really helped me now! Thanks a lot for your contribution for medical education!

  • @dskim24
    @dskim24 Год назад +5

    That first sentence you open with; yup, hence I'm here.

  • @shadysid5570
    @shadysid5570 Год назад

    Wow, this video has every bit of information I needed

  • @MommaBearsCorner
    @MommaBearsCorner 7 дней назад

    tks for explaining this so well.

  • @wellermasong6984
    @wellermasong6984 2 года назад

    Thank you for this. Brief and concise. God bless!❤

  • @alexahmed2581
    @alexahmed2581 Год назад

    simplified and explained very well thank you!

  • @maisaaabuwasel6040
    @maisaaabuwasel6040 8 месяцев назад

    what an amazing video! great explanation and very helpful memorizing tools!

  • @monicag918
    @monicag918 2 месяца назад

    This video is amazing!!! Thank you so much

  • @bivoist
    @bivoist 8 месяцев назад

    Thank you so much. This nice explanation helped me alot.

  • @FelixNgoge
    @FelixNgoge 11 месяцев назад

    Thanks am from long holiday this context has really recaped. My mind

  • @gabrielehiraoka4853
    @gabrielehiraoka4853 Год назад

    Thank you for this video! Studying for hematology for my lab tech exam and this video really helped

  • @alexandradelliou
    @alexandradelliou 6 месяцев назад

    This is your first video that I watched. SUBSCRIBING!

  • @angrygunther2569
    @angrygunther2569 3 года назад

    Excellent video! I really love these mnemonics.

  • @ReyShen-tv3xj
    @ReyShen-tv3xj Год назад

    hello, I thought LMWH didn’t really have a reversal agent, which is why heparin is preferred in critical care situations

  • @jazzygirl160
    @jazzygirl160 2 года назад

    thank you this helped me differentiate between all 3

  • @DrAmmanuel
    @DrAmmanuel 2 года назад

    Very helpful , especially the tenis mnemonic

  • @elpedro812
    @elpedro812 3 года назад +2

    It's very helpful and very well explained! TY

  • @ritikasrivastava4084
    @ritikasrivastava4084 9 месяцев назад

    U r best all in one helps 🙏🙏🙏

  • @rebbekandahuma2173
    @rebbekandahuma2173 Год назад

    Awesome! Thank you❤️

  • @lammeesakc867
    @lammeesakc867 Год назад

    Thankyou for these❤

  • @hanisofiamazlan794
    @hanisofiamazlan794 Год назад

    Love it, thank you so much

  • @wajeehashah7103
    @wajeehashah7103 3 года назад

    Awesome video thanks dudes

  • @tejasmahajan1557
    @tejasmahajan1557 6 месяцев назад

    Nice explanation

  • @ortaekvator
    @ortaekvator 9 месяцев назад

    Harikaa çok teşekkür ederim. Kanalın ilerleyiş biçimini de çok beğendim emoji kullanmanız odaklanmayı kolaylaştırıyor. Arkadaşlarıma önereceğim inşallah❤

  • @michellegordon3319
    @michellegordon3319 3 года назад

    Informative, thorough and to the point. Thank you 🙏

    • @RhesusMedicine
      @RhesusMedicine  3 года назад

      Glad it helped, thanks for watching 😁

  • @dr.leelaram
    @dr.leelaram Год назад

    Great lecture❤

  • @АлександрМуравский-з3ю

    Omg. Thx very much ❤

  • @stevebradford3939
    @stevebradford3939 Год назад +1

    its very easy to forget.

  • @dumindasamarawickrama3795
    @dumindasamarawickrama3795 8 месяцев назад

    Great work

  • @shinigglory3689
    @shinigglory3689 3 года назад

    Thanks for this informational ❤️❤️

  • @sheliceallen68
    @sheliceallen68 3 года назад

    Can you give an example of injuries that would release contact activation or cause tissue factor to be released?

    • @RhesusMedicine
      @RhesusMedicine  3 года назад +1

      Hi Shelice! Generally speaking, we'd mainly be looking at trauma- which is of course a situation where coagulation would be a physiological attempt to reduce blood loss.
      There are of course others, but there are technical differences. Endothelial dysfunction, for example, may result from many causes including smoking, hypertension, diabetes mellitus, dyslipidemia etc. Endothelial dysfunction has been shown to contribute to the pathogenesis of thrombosis, but this is more of a pathological process rather than a physiological process seen in response to trauma!
      Hope that helps somewhat. Thanks for watching!

  • @curelord
    @curelord Месяц назад

    very good 👍

  • @ameliamorton1686
    @ameliamorton1686 Год назад

    Thank you God bless

  • @EJTDB
    @EJTDB 2 года назад

    You are magnificent! I will never forget this!

  • @macsuip2
    @macsuip2 Год назад

    Good job

  • @alangoomez
    @alangoomez 9 месяцев назад

    Thank you ❤

  • @timothywiebe4714
    @timothywiebe4714 2 года назад

    Great one! TY

  • @A.2.0.2.4-5
    @A.2.0.2.4-5 3 года назад

    WONDERFUL.

  • @nagatsatti8426
    @nagatsatti8426 3 года назад

    Thank you very much doctor

  • @swatimishra697
    @swatimishra697 4 месяца назад

    THANK YOU :)

  • @nonyeonochie3250
    @nonyeonochie3250 Год назад

    Perfect!!

  • @sabaamjad632
    @sabaamjad632 Год назад

    why i saw this so late ALSO please mention heparin monitoring is done by APTT n why?

  • @kenp2396
    @kenp2396 2 года назад

    Is platelet factor 3 the same as tissue factor/factor 3?

  • @marine-se2vl
    @marine-se2vl 10 месяцев назад

    great video

  • @janaadham9011
    @janaadham9011 Месяц назад

    Brilliant

  • @aamirmuhammad7962
    @aamirmuhammad7962 3 года назад

    Wow amazing 🤩

  • @reagananesthetist-ss4bh9wr9
    @reagananesthetist-ss4bh9wr9 Год назад

    Fantastic

  • @JzQ21
    @JzQ21 4 года назад

    Thank you so much!

  • @bryanamante7532
    @bryanamante7532 4 года назад

    👏 Amazing. Thanks!

  • @jacquelineparadzayi5859
    @jacquelineparadzayi5859 3 года назад

    Amazing 👌simply amazing

  • @hk6474
    @hk6474 2 года назад

    Good sheet

  • @stacymethvin3426
    @stacymethvin3426 3 года назад

    Thank you ! I needed this for my exam tomorrow and yes....I will be back as well, but the calcium Ion is Factor IV, not V. Just so you can make the change.

    • @RhesusMedicine
      @RhesusMedicine  3 года назад +1

      Hi Stacy! Thank you! (Also for the coffee!! 😁). I'm so glad it helped - as for the Factor V, you are absolutely correct that Factor IV is a calcium ion, in the video I say that Factor V is needed alongside a Calcium Ion, I can see however how it could cause confusion as they're listed together- I should have made it clearer! Thank you again for your support, it really means a lot. All the best with your exam :)

  • @sohanirahman720
    @sohanirahman720 10 месяцев назад

    Tissue factor II is inhibited by heparin

  • @ephraimjosephfalcunit5768
    @ephraimjosephfalcunit5768 3 года назад

    damn, that was good! thank you!

  • @09ch03
    @09ch03 3 года назад +1

    hey the calcium is factor IV
    na

  • @kenp2396
    @kenp2396 2 года назад

    My professor says run(one) to(two) the five and ten store.

  • @gem270
    @gem270 4 года назад

    Thanks. It’s starting to click

  • @jamalazmat9617
    @jamalazmat9617 13 дней назад

    Tennis excellent

  • @switchblade8028
    @switchblade8028 3 месяца назад

    Just wow

  • @andycheng2191
    @andycheng2191 3 месяца назад

    SN0T makes your Vit (K)LOT. Seven, Nine, 10, Two (SNOT)

  • @zux1153
    @zux1153 4 года назад +1

    👏👏👏👏👏

  • @samjones1320
    @samjones1320 7 месяцев назад

    I love you

  • @dianneloma9047
    @dianneloma9047 Год назад

    idracizumab or idarucizumab?

  • @zahidhussain_8
    @zahidhussain_8 Год назад

    Rhesus monkey😎

  • @JiminFanx
    @JiminFanx 2 месяца назад

    Thank you 💘💘

  • @wiamalbouzidi7778
    @wiamalbouzidi7778 2 года назад

    Thank you so much !

  • @tonythomas55
    @tonythomas55 2 месяца назад

    Good job